List of works by Gerhard A. Coetzee

4C-seq revealed long-range interactions of a functional enhancer at the 8q24 prostate cancer risk locus

scientific article published on 03 March 2016

5-Methylcytosine as an Endogenous Mutagen in the Human LDL Receptor and p53 Genes ⬇️

scientific article published on September 14, 1990

5-Methylcytosine as an endogenous mutagen in the p53 tumor suppressor gene

scientific article published on 01 January 1991

5-bromo-2'-deoxyuridine-stimulated calcium ion- or magnesium ion-dependent ecto-(adenosine triphosphatase) activity of cultured hamster cardiac cells ⬇️

scientific article published on June 15, 1977

8q24 prostate, breast, and colon cancer risk loci show tissue-specific long-range interaction with MYC.

scientific article

A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry

scientific article

A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer

scientific article published on 14 September 2014

A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11.

scientific article

A noncoding RNA antisense to moesin at 5p14.1 in autism

scientific article

A nonsense mutation in the LDL receptor gene leads to familial hypercholesterolemia in the Druze sect ⬇️

scientific article published on February 1, 1992

A polymorphism in intron 6 of the CYP17 gene ⬇️

scientific article published on July 1, 1997

A rare variant, which destroys a FoxA1 site at 8q24, is associated with prostate cancer risk

scientific article published on 15 January 2012

A systematic approach to understand the functional consequences of non-protein coding risk regions

scientific article published on 23 January 2010

An enhancer from the 8q24 prostate cancer risk region is sufficient to direct reporter gene expression to a subset of prostate stem-like epithelial cells in transgenic mice

scientific article published on 25 January 2012

Androgen receptor responsive enhancers are flanked by consistently-positioned H3-acetylated nucleosomes.

scientific article

Ascorbate increases the number of low density lipoprotein receptors in cultured arterial smooth muscle cells ⬇️

scientific article published on 01 May 1983

Biological implications and regulatory mechanisms of long-range chromosomal interactions.

scientific article published on 18 June 2013

Cardiac myofibrillar phosphorylation and adenosine triphosphatase activity

scientific article published on November 24, 1979

Carotenoids/vitamin C and smoking-related bladder cancer

scientific article published in June 2004

Cell-type-specific enrichment of risk-associated regulatory elements at ovarian cancer susceptibility loci

scientific article published on 24 March 2015

Chromatin accessibility reveals insights into androgen receptor activation and transcriptional specificity

scientific article

Common variants at the CHEK2 gene locus and risk of epithelial ovarian cancer

scientific article

Comprehensive functional annotation of 77 prostate cancer risk loci

scientific article published on 30 January 2014

Comprehensive functional annotation of seventy-one breast cancer risk Loci

scientific article

Corepressor effect on androgen receptor activity varies with the length of the CAG encoded polyglutamine repeat and is dependent on receptor/corepressor ratio in prostate cancer cells.

scientific article published in June 2011

Corrigendum: genome-wide association study of colorectal cancer identifies six new susceptibility loci

scientific article published on 26 October 2015

Cytochrome P450c17alpha gene (CYP17) polymorphism is associated with serum estrogen and progesterone concentrations.

scientific article published in February 1998

Dynamic nucleosome-depleted regions at androgen receptor enhancers in the absence of ligand in prostate cancer cells

scientific article published on 3 October 2011

Effects of 5-bromo-2'-deoxyuridine on beating heart cell cultures from neonatal hamsters ⬇️

scientific article published on June 15, 1977

Enrichment of risk SNPs in regulatory regions implicate diverse tissues in Parkinson's disease etiology

scientific article published on 27 July 2016

Epigenomic analysis of Parkinson's disease neurons identifies Tet2 loss as neuroprotective

scientific article published on 17 August 2020

Evidence of an X-linked or recessive genetic component to prostate cancer risk ⬇️

scientific article published on August 1, 1995

Evidence that recycling of low density lipoprotein receptors does not depend on delivery of receptors to lysosomes ⬇️

scientific article published on August 31, 1982

Expression and functional role of orphan receptor GPR158 in prostate cancer growth and progression

scientific article

FunciSNP: an R/bioconductor tool integrating functional non-coding data sets with genetic association studies to identify candidate regulatory SNPs

scientific article

GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer

scientific article published on April 2013

Genetic determinants in the metabolism of bladder carcinogens in relation to risk of bladder cancer

scientific article published on 09 June 2008

Genetically engineered stem cell-derived neurons can be rendered resistant to alpha-synuclein aggregate pathology

scientific article published on 20 January 2019

Genome-wide Runx2 occupancy in prostate cancer cells suggests a role in regulating secretion

scientific article published on 19 December 2011

Genome-wide association studies identify four ER negative-specific breast cancer risk loci

scientific article published in April 2013

Genome-wide association study of colorectal cancer identifies six new susceptibility loci

scientific article published on 07 July 2015

Heterogenous effect of androgen receptor CAG tract length on testicular germ cell tumor risk: shorter repeats associated with seminoma but not other histologic types

scientific article

Hypertension, diuretics and antihypertensives in relation to bladder cancer

scientific article

Identification and characterization of functional risk variants for colorectal cancer mapping to chromosome 11q23.1.

scientific article

Identification and functional annotation of GWAS risk SNPs.

scientific article published in December 2011

Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31.

scientific article published on January 2013

Identification and properties of the proline664-leucine mutant LDL receptor in South Africans of Indian origin ⬇️

scientific article published on November 1, 1992

Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis

scientific article published on 22 December 2012

Identification of a Novel Mucin Gene HCG22 Associated With Steroid-Induced Ocular Hypertension

scientific article published on April 2015

Identification of three isoform patterns of human serum amyloid A protein ⬇️

scientific article published on February 15, 1988

In vitro metabolism of LDL labeled with a nondegradable cholesteryl ester analogue ⬇️

scientific article published on May 1, 1984

Integration of multiethnic fine-mapping and genomic annotation to prioritize candidate functional SNPs at prostate cancer susceptibility regions

scientific article

Knockdown of the cochaperone SGTA results in the suppression of androgen and PI3K/Akt signaling and inhibition of prostate cancer cell proliferation.

scientific article published on 6 July 2013

Low density lipoprotein receptor mutations in South African homozygous familial hypercholesterolemic patients ⬇️

scientific article published on May 1, 1984

Low-density lipoprotein receptor point mutation results in expression of both active and inactive surface forms of the same mutant receptor

scientific article published on December 29, 1992

Metabolism of cytoplasmic triacylglycerol in cultured aortic smooth muscle cells ⬇️

scientific article published on August 1, 1981

Modulation by sodium ascorbate of the effect of chloroquine on low density lipoprotein retention and degradation in cultured human skin fibroblasts ⬇️

scientific article published on March 1, 1979

Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans

scientific article published on 29 May 2015

Myosin in primary cultures of hamster heart cells ⬇️

scientific article published on March 1, 1978

Novel Common Genetic Susceptibility Loci for Colorectal Cancer

scientific article published on 01 February 2019

Parkinson's disease genetic risk in a midbrain neuronal cell line

scientific article published on 24 February 2018

Parkinson's disease-associated genetic variation is linked to quantitative expression of inflammatory genes

scientific article

Permanent hair dyes and bladder cancer: risk modification by cytochrome P4501A2 and N-acetyltransferases 1 and 2.

scientific article published in March 2003

Post-GWAS knowledge gap: the how, where, and when

scientific article published on 09 September 2020

Principles for the post-GWAS functional characterization of cancer risk loci

scientific article published in June 2011

Prostate Cancer Susceptibility in Men of African Ancestry at 8q24

scientific article published on 27 January 2016

Reducing GWAS Complexity

scientific article

Regulation of adult bone turnover by sex steroids

scientific article

Scavenger lipoprotein receptors are more effective in ligand internalization than low density lipoprotein receptors in human monocyte-macrophages ⬇️

scientific article published on October 31, 1983

Shorter androgen receptor CAG repeat lengths associated with cryptorchidism risk among Hispanic white boys.

scientific article published on 21 December 2011

Subdomain structure of the co-chaperone SGTA and activity of its androgen receptor client

scholarly article by Andrew P Trotta published in June 2012

TPL2/COT/MAP3K8 (TPL2) activation promotes androgen depletion-independent (ADI) prostate cancer growth

scientific article

The Androgen Receptor CAG Repeat and Prostate Cancer Risk

scientific article published on January 1, 2003

The Five Dimensions of Parkinson's Disease Genetic Risk

scientific article published on 15 December 2017

The usefulness of prostate cancer genome-wide association studies.

scientific article

Understanding Non-Mendelian Genetic Risk

scientific article published on 01 August 2019

Uptake and degradation of low density lipoproteins (LDL) by confluent, contact-inhibited bovine and human endothelial cells exposed to physiological concentrations of LDL ⬇️

scientific article published on August 1, 1979

motifbreakR: an R/Bioconductor package for predicting variant effects at transcription factor binding sites

scientific article

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