List of works - Anne P Beigneux

A disordered acidic domain in GPIHBP1 harboring a sulfated tyrosine regulates lipoprotein lipase

scientific article published on 13 June 2018

AGPAT6 is a novel microsomal glycerol-3-phosphate acyltransferase

scientific article

ATP-citrate lyase deficiency in the mouse

scientific article

Abnormal patterns of lipoprotein lipase release into the plasma in GPIHBP1-deficient mice.

scientific article published on 8 October 2008

Agpat6 deficiency causes subdermal lipodystrophy and resistance to obesity

scientific journal article

Agpat6--a novel lipid biosynthetic gene required for triacylglycerol production in mammary epithelium

scientific journal article

An ELISA for quantifying GPIHBP1 autoantibodies and making a diagnosis of the GPIHBP1 autoantibody syndrome

scientific article published on 01 October 2018

An LPL-specific monoclonal antibody, 88B8, that abolishes the binding of LPL to GPIHBP1.

scientific article published on 5 August 2016

An enzyme-linked immunosorbent assay for measuring GPIHBP1 levels in human plasma or serum.

scientific article published in November 2017

An upstream enhancer regulates Gpihbp1 expression in a tissue-specific manner

scientific article published on 31 December 2018

Angiopoietin-like 4 promotes intracellular degradation of lipoprotein lipase in adipocytes

scientific article published on 31 March 2016

Apolipoprotein C-III inhibits triglyceride hydrolysis by GPIHBP1-bound LPL.

scientific article

Assembly of lipoprotein particles containing apolipoprotein-B: structural model for the nascent lipoprotein particle

scientific article

Assessing mechanisms of GPIHBP1 and lipoprotein lipase movement across endothelial cells.

scientific article

Assessing the role of the glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 (GPIHBP1) three-finger domain in binding lipoprotein lipase

scientific article

Binding preferences for GPIHBP1, a glycosylphosphatidylinositol-anchored protein of capillary endothelial cells

scientific article

Blocking protein farnesyltransferase improves nuclear shape in fibroblasts from humans with progeroid syndromes

scientific article

Cholesterol intake modulates plasma triglyceride levels in glycosylphosphatidylinositol HDL-binding protein 1-deficient mice

scientific article

Chylomicronemia From GPIHBP1 Autoantibodies Successfully Treated With Rituximab: A Case Report

scientific article published on 11 August 2020

Chylomicronemia elicits atherosclerosis in mice--brief report

scientific article published on 08 October 2009

Chylomicronemia from GPIHBP1 autoantibodies

scientific article published on 18 September 2020

Chylomicronemia mutations yield new insights into interactions between lipoprotein lipase and GPIHBP1

scientific article

Chylomicronemia with a mutant GPIHBP1 (Q115P) that cannot bind lipoprotein lipase

scientific article

Chylomicronemia with low postheparin lipoprotein lipase levels in the setting of GPIHBP1 defects

scientific article

D-aspartate regulates melanocortin formation and function: behavioral alterations in D-aspartate oxidase-deficient mice

scientific journal article

Disruption of the phosphatidylserine decarboxylase gene in mice causes embryonic lethality and mitochondrial defects

scientific article

ESCRT-III dysfunction causes autophagosome accumulation and neurodegeneration

scientific journal article

Equivalent binding of wild-type lipoprotein lipase (LPL) and S447X-LPL to GPIHBP1, the endothelial cell LPL transporter

scientific article

GPIHBP1 and Plasma Triglyceride Metabolism

scientific article published on 14 May 2016

GPIHBP1 and lipolysis: an update

scientific article

GPIHBP1 and the processing of triglyceride-rich lipoproteins

scientific article

GPIHBP1 autoantibodies in a patient with unexplained chylomicronemia.

scientific article published on 13 June 2017

GPIHBP1 autoantibody syndrome during interferon β1a treatment

scientific article published on 24 October 2018

GPIHBP1 expression in gliomas promotes utilization of lipoprotein-derived nutrients.

scientific article published on 6 June 2019

GPIHBP1 is responsible for the entry of lipoprotein lipase into capillaries

scientific article

GPIHBP1 missense mutations often cause multimerization of GPIHBP1 and thereby prevent lipoprotein lipase binding.

scientific article published on 11 November 2014

GPIHBP1, a GPI-anchored protein required for the lipolytic processing of triglyceride-rich lipoproteins

scientific article published on 14 October 2008

GPIHBP1, an endothelial cell transporter for lipoprotein lipase

scientific article

GPIHBP1: an endothelial cell molecule important for the lipolytic processing of chylomicrons

scientific article

Glycosylation of Asn-76 in mouse GPIHBP1 is critical for its appearance on the cell surface and the binding of chylomicrons and lipoprotein lipase

scientific article

Glycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1 plays a critical role in the lipolytic processing of chylomicrons

scientific article

High-resolution imaging of dietary lipids in cells and tissues by NanoSIMS analysis.

scientific article

Highly conserved cysteines within the Ly6 domain of GPIHBP1 are crucial for the binding of lipoprotein lipase.

scientific article published on 02 September 2009

Human CYP7A1 deficiency: progress and enigmas

scientific article

Impaired thermogenesis and sharp increases in plasma triglyceride levels in GPIHBP1-deficient mice during cold exposure

scientific article published on 15 February 2018

Inactivation of Icmt inhibits transformation by oncogenic K-Ras and B-Raf

scientific article

Lipoprotein size and susceptibility to atherosclerosis--insights from genetically modified mouse models

scientific article

Monoclonal antibodies that bind to the Ly6 domain of GPIHBP1 abolish the binding of LPL.

scientific article published on 15 November 2016

Multimerization of glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 (GPIHBP1) and familial chylomicronemia from a serine-to-cysteine substitution in GPIHBP1 Ly6 domain

scientific article

Mutating a conserved cysteine in GPIHBP1 reduces amounts of GPIHBP1 in capillaries and abolishes LPL binding.

scientific article published on 5 May 2017

Mutation of conserved cysteines in the Ly6 domain of GPIHBP1 in familial chylomicronemia

scientific article

Mutations in lipoprotein lipase that block binding to the endothelial cell transporter GPIHBP1

scientific article

NanoSIMS Analysis of Intravascular Lipolysis and Lipid Movement across Capillaries and into Cardiomyocytes

New wrinkles in lipoprotein lipase biology.

scientific article

Normal binding of lipoprotein lipase, chylomicrons, and apo-AV to GPIHBP1 containing a G56R amino acid substitution

scientific article published in December 2007

Palmoplantar Keratoderma in Slurp2-Deficient Mice

scientific article

Palmoplantar keratoderma along with neuromuscular and metabolic phenotypes in Slurp1-deficient mice

scientific article

Prenylcysteine lyase deficiency in mice results in the accumulation of farnesylcysteine and geranylgeranylcysteine in brain and liver

scientific journal article

Reciprocal metabolic perturbations in the adipose tissue and liver of GPIHBP1-deficient mice.

scientific article published on 15 December 2011

Regulation of prelamin A but not lamin C by miR-9, a brain-specific microRNA.

scientific article published on 30 January 2012

Structure of the lipoprotein lipase-GPIHBP1 complex that mediates plasma triglyceride hydrolysis

scientific article published on 17 December 2018

The GPIHBP1-LPL complex is responsible for the margination of triglyceride-rich lipoproteins in capillaries

scientific article published on 10 April 2014

The acidic domain of GPIHBP1 is important for the binding of lipoprotein lipase and chylomicrons

scientific article

The acidic domain of the endothelial membrane protein GPIHBP1 stabilizes lipoprotein lipase activity by preventing unfolding of its catalytic domain.

scientific article published on 3 January 2016

The expression of GPIHBP1, an endothelial cell binding site for lipoprotein lipase and chylomicrons, is induced by peroxisome proliferator-activated receptor-gamma

scientific article published on 11 September 2008

Unexpected expression pattern for glycosylphosphatidylinositol-anchored HDL-binding protein 1 (GPIHBP1) in mouse tissues revealed by positron emission tomography scanning.

scientific article

List of works by Anne P Beigneux

A disordered acidic domain in GPIHBP1 harboring a sulfated tyrosine regulates lipoprotein lipase

AGPAT6 is a novel microsomal glycerol-3-phosphate acyltransferase

ATP-citrate lyase deficiency in the mouse

Abnormal patterns of lipoprotein lipase release into the plasma in GPIHBP1-deficient mice.

Agpat6 deficiency causes subdermal lipodystrophy and resistance to obesity

Agpat6--a novel lipid biosynthetic gene required for triacylglycerol production in mammary epithelium

An ELISA for quantifying GPIHBP1 autoantibodies and making a diagnosis of the GPIHBP1 autoantibody syndrome

An LPL-specific monoclonal antibody, 88B8, that abolishes the binding of LPL to GPIHBP1.

An enzyme-linked immunosorbent assay for measuring GPIHBP1 levels in human plasma or serum.

An upstream enhancer regulates Gpihbp1 expression in a tissue-specific manner

Angiopoietin-like 4 promotes intracellular degradation of lipoprotein lipase in adipocytes

Apolipoprotein C-III inhibits triglyceride hydrolysis by GPIHBP1-bound LPL.

Assembly of lipoprotein particles containing apolipoprotein-B: structural model for the nascent lipoprotein particle

Assessing mechanisms of GPIHBP1 and lipoprotein lipase movement across endothelial cells.

Assessing the role of the glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 (GPIHBP1) three-finger domain in binding lipoprotein lipase

Binding preferences for GPIHBP1, a glycosylphosphatidylinositol-anchored protein of capillary endothelial cells

Blocking protein farnesyltransferase improves nuclear shape in fibroblasts from humans with progeroid syndromes

Cholesterol intake modulates plasma triglyceride levels in glycosylphosphatidylinositol HDL-binding protein 1-deficient mice

Chylomicronemia From GPIHBP1 Autoantibodies Successfully Treated With Rituximab: A Case Report

Chylomicronemia elicits atherosclerosis in mice--brief report

Chylomicronemia from GPIHBP1 autoantibodies

Chylomicronemia mutations yield new insights into interactions between lipoprotein lipase and GPIHBP1

Chylomicronemia with a mutant GPIHBP1 (Q115P) that cannot bind lipoprotein lipase

Chylomicronemia with low postheparin lipoprotein lipase levels in the setting of GPIHBP1 defects

D-aspartate regulates melanocortin formation and function: behavioral alterations in D-aspartate oxidase-deficient mice

Disruption of the phosphatidylserine decarboxylase gene in mice causes embryonic lethality and mitochondrial defects

ESCRT-III dysfunction causes autophagosome accumulation and neurodegeneration

Equivalent binding of wild-type lipoprotein lipase (LPL) and S447X-LPL to GPIHBP1, the endothelial cell LPL transporter

GPIHBP1 and Plasma Triglyceride Metabolism

GPIHBP1 and lipolysis: an update

GPIHBP1 and the processing of triglyceride-rich lipoproteins

GPIHBP1 autoantibodies in a patient with unexplained chylomicronemia.

GPIHBP1 autoantibody syndrome during interferon β1a treatment

GPIHBP1 expression in gliomas promotes utilization of lipoprotein-derived nutrients.

GPIHBP1 is responsible for the entry of lipoprotein lipase into capillaries

GPIHBP1 missense mutations often cause multimerization of GPIHBP1 and thereby prevent lipoprotein lipase binding.

GPIHBP1, a GPI-anchored protein required for the lipolytic processing of triglyceride-rich lipoproteins

GPIHBP1, an endothelial cell transporter for lipoprotein lipase

GPIHBP1: an endothelial cell molecule important for the lipolytic processing of chylomicrons

Glycosylation of Asn-76 in mouse GPIHBP1 is critical for its appearance on the cell surface and the binding of chylomicrons and lipoprotein lipase

Glycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1 plays a critical role in the lipolytic processing of chylomicrons

High-resolution imaging of dietary lipids in cells and tissues by NanoSIMS analysis.

Highly conserved cysteines within the Ly6 domain of GPIHBP1 are crucial for the binding of lipoprotein lipase.

Human CYP7A1 deficiency: progress and enigmas

Impaired thermogenesis and sharp increases in plasma triglyceride levels in GPIHBP1-deficient mice during cold exposure

Inactivation of Icmt inhibits transformation by oncogenic K-Ras and B-Raf

Lipoprotein size and susceptibility to atherosclerosis--insights from genetically modified mouse models

Monoclonal antibodies that bind to the Ly6 domain of GPIHBP1 abolish the binding of LPL.

Multimerization of glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 (GPIHBP1) and familial chylomicronemia from a serine-to-cysteine substitution in GPIHBP1 Ly6 domain

Mutating a conserved cysteine in GPIHBP1 reduces amounts of GPIHBP1 in capillaries and abolishes LPL binding.

Mutation of conserved cysteines in the Ly6 domain of GPIHBP1 in familial chylomicronemia

Mutations in lipoprotein lipase that block binding to the endothelial cell transporter GPIHBP1

NanoSIMS Analysis of Intravascular Lipolysis and Lipid Movement across Capillaries and into Cardiomyocytes

New wrinkles in lipoprotein lipase biology.

Normal binding of lipoprotein lipase, chylomicrons, and apo-AV to GPIHBP1 containing a G56R amino acid substitution

Palmoplantar Keratoderma in Slurp2-Deficient Mice

Palmoplantar keratoderma along with neuromuscular and metabolic phenotypes in Slurp1-deficient mice

Prenylcysteine lyase deficiency in mice results in the accumulation of farnesylcysteine and geranylgeranylcysteine in brain and liver

Reciprocal metabolic perturbations in the adipose tissue and liver of GPIHBP1-deficient mice.

Regulation of prelamin A but not lamin C by miR-9, a brain-specific microRNA.

Structure of the lipoprotein lipase-GPIHBP1 complex that mediates plasma triglyceride hydrolysis

The GPIHBP1-LPL complex is responsible for the margination of triglyceride-rich lipoproteins in capillaries

The acidic domain of GPIHBP1 is important for the binding of lipoprotein lipase and chylomicrons

The acidic domain of the endothelial membrane protein GPIHBP1 stabilizes lipoprotein lipase activity by preventing unfolding of its catalytic domain.

The expression of GPIHBP1, an endothelial cell binding site for lipoprotein lipase and chylomicrons, is induced by peroxisome proliferator-activated receptor-gamma

Unexpected expression pattern for glycosylphosphatidylinositol-anchored HDL-binding protein 1 (GPIHBP1) in mouse tissues revealed by positron emission tomography scanning.