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List of works by Meredith M Regan

8q24 prostate, breast, and colon cancer risk loci show tissue-specific long-range interaction with MYC.

scientific article

A risk score based on histopathological features predicts higher risk of distant recurrence in premenopausal patients with lymph node-negative endocrine-responsive breast cancer

scientific article published on 29 June 2012

Absence of relationship between steroid hormone levels and prostate cancer tumor grade

scientific article published on 26 November 2008

Absolute Benefit of Adjuvant Endocrine Therapies for Premenopausal Women With Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Early Breast Cancer: TEXT and SOFT Trials.

scientific article published on 04 April 2016

Absolute Improvements in Freedom From Distant Recurrence to Tailor Adjuvant Endocrine Therapies for Premenopausal Women: Results From TEXT and SOFT

scientific article published on 16 October 2019

Adjuvant Ovarian Suppression in Premenopausal Breast Cancer

scientific article published on 01 April 2015

Adjuvant Systemic Treatment of Premenopausal Women With Hormone Receptor-Positive Early Breast Cancer: Lights and Shadows

scientific article published on 27 February 2019

Adjuvant Tamoxifen Plus Ovarian Function Suppression Versus Tamoxifen Alone in Premenopausal Women With Early Breast Cancer: Patient-Reported Outcomes in the Suppression of Ovarian Function Trial.

scientific article published on 28 March 2016

Adjuvant exemestane with ovarian suppression in premenopausal breast cancer

scientific article

Adjuvant letrozole versus tamoxifen according to centrally-assessed ERBB2 status for postmenopausal women with endocrine-responsive early breast cancer: supplementary results from the BIG 1-98 randomised trial.

scientific article

Adjuvant ovarian function suppression and cognitive function in women with breast cancer.

scientific article published on 19 April 2016

Adjuvant ovarian suppression in premenopausal breast cancer

scientific article

Adjuvant treatment of premenopausal women with endocrine-responsive early breast cancer: design of the TEXT and SOFT trials.

scientific article published on 02 October 2013

Analysis of the 10q11 cancer risk locus implicates MSMB and NCOA4 in human prostate tumorigenesis

scientific article

Apatorsen plus docetaxel versus docetaxel alone in platinum-resistant metastatic urothelial carcinoma (Borealis-2).

scientific article published on 16 May 2018

Are SOFT and TEXT results practice changing and how?

scientific article

Assessing health-related quality of life in patients with breast cancer: a reply to Maratia et al.

scientific article published on 5 September 2017

Association Between Combined TMPRSS2:ERG and PCA3 RNA Urinary Testing and Detection of Aggressive Prostate Cancer.

scientific article

Axillary dissection versus no axillary dissection in patients with sentinel-node micrometastases (IBCSG 23-01): a phase 3 randomised controlled trial

scientific article published on 11 March 2013

CYP19A1 polymorphisms and clinical outcomes in postmenopausal women with hormone receptor-positive breast cancer in the BIG 1-98 trial

scientific article published on 3 May 2015

CYP2D6 genotype and tamoxifen response in postmenopausal women with endocrine-responsive breast cancer: the breast international group 1-98 trial

scientific article published on 6 March 2012

Carbonic anhydrase IX as a predictive biomarker of response to kidney cancer therapy

scientific article published on June 2008

Carbonic anhydrase IX expression predicts outcome of interleukin 2 therapy for renal cancer

scientific article published in May 2005

Cell kinetic studies fail to identify sequentially proliferating progenitors as the major source of epithelial renewal in the adult murine prostate

scientific article published on 29 May 2015

Chemoendocrine compared with endocrine adjuvant therapies for node-negative breast cancer: predictive value of centrally reviewed expression of estrogen and progesterone receptors--International Breast Cancer Study Group.

scientific article

Cholesterol, Cholesterol-Lowering Medication Use, and Breast Cancer Outcome in the BIG 1-98 Study

scientific article published on 13 February 2017

Clinical Trial Design and Endpoints for Stage IV Melanoma in the Modern Era.

scientific article published in January 2017

Clinical and analytical validation of Ki-67 in 9069 patients from IBCSG VIII + IX, BIG1-98 and GeparTrio trial: systematic modulation of interobserver variance in a comprehensive in silico ring trial

scientific article published on 07 May 2019

Clinical and economic outcomes of treatment sequences for intermediate- to poor-risk advanced renal cell carcinoma

scientific article published on 29 January 2020

Clinical behavior of recurrent hormone receptor-positive breast cancer by adjuvant endocrine therapy within the Breast International Group 1-98 clinical trial

scientific article published on 08 December 2020

Combination of radiofrequency ablation with antiangiogenic therapy for tumor ablation efficacy: study in mice

scientific article published on 01 August 2007

Comparative effectiveness study of patient-reported outcomes after proton therapy or intensity-modulated radiotherapy for prostate cancer

scientific article

Correction: Quality of life under extended continuous versus intermittent adjuvant letrozole in lymph node-positive, early breast cancer patients: the SOLE randomised phase 3 trial

scientific article published on 01 March 2020

Cumulative incidence of cardiovascular events under tamoxifen and letrozole alone and in sequence: a report from the BIG 1-98 trial

scientific article published on 07 November 2020

Cytochrome P-450 2D6 (CYP2D6) Genotype and Breast Cancer Recurrence in Tamoxifen-Treated Patients: Evaluating the Importance of Loss of Heterozygosity

scientific article published on 17 December 2016

DNA derived from archival tumor specimens can be used for germline pharmacogenetic analyses

scientific article published on 29 July 2020

Digital quantification of gene expression in sequential breast cancer biopsies reveals activation of an immune response

scientific article

Distinct prognostic role of prostate-specific antigen doubling time and velocity at emergence of androgen independence in patients treated with chemotherapy

scientific article published on September 2007

Docetaxel, estramustine, and 15-month androgen deprivation for men with prostate-specific antigen progression after definitive local therapy for prostate cancer

scientific article published on 01 December 2006

Does arterial spin-labeling MR imaging-measured tumor perfusion correlate with renal cell cancer response to antiangiogenic therapy in a mouse model?

scientific article published on June 2009

Dual Blockade of c-MET and the Androgen Receptor in Metastatic Castration-Resistant Prostate Cancer: A Phase 1 Study of Concurrent Enzalutamide and Crizotinib

scientific article published on 17 September 2020

Duration of Androgen Deprivation Therapy for High-Risk Prostate Cancer: Application of Randomized Trial Data in a Tertiary Referral Cancer Center

scientific article

ESR1 and ESR2 polymorphisms in the BIG 1-98 trial comparing adjuvant letrozole versus tamoxifen or their sequence for early breast cancer

scientific article published on 21 November 2015

Efficacy of Chemotherapy for ER-Negative and ER-Positive Isolated Locoregional Recurrence of Breast Cancer: Final Analysis of the CALOR Trial.

scientific article published on 14 February 2018

Efficacy of androgen deprivation therapy (ADT) in patients with advanced prostate cancer

article

Efficacy of nilutamide as secondary hormonal therapy in androgen-independent prostate cancer

scientific article

Estimation of historical control rate for a single arm de-escalation study - Application to the POSITIVE trial

scientific article published on 02 June 2020

Estrogen and Progesterone Receptor Testing in Breast Cancer: ASCO/CAP Guideline Update

scientific article published on 13 January 2020

Estrogen and Progesterone Receptor Testing in Breast Cancer: American Society of Clinical Oncology/College of American Pathologists Guideline Update

scientific article published on 13 January 2020

Evaluation of the 8q24 prostate cancer risk locus and MYC expression.

scientific article

Event-Free Survival, a Prostate-Specific Antigen-Based Composite End Point, Is Not a Surrogate for Overall Survival in Men With Localized Prostate Cancer Treated With Radiation

scientific article published on 18 June 2020

Exemestane with Ovarian Suppression in Premenopausal Breast Cancer

scientific article published on 01 October 2014

Expanded Prostate Cancer Index Composite-26 (EPIC-26) Online: Validation of an Internet-Based Instrument for Assessment of Health-Related Quality of Life After Treatment for Localized Prostate Cancer

scientific article published on 18 February 2019

Extended adjuvant intermittent letrozole versus continuous letrozole in postmenopausal women with breast cancer (SOLE): a multicentre, open-label, randomised, phase 3 trial

scientific article published on 17 November 2017

Gene expression profile of mouse prostate tumors reveals dysregulations in major biological processes and identifies potential murine targets for preclinical development of human prostate cancer therapy.

scientific article

Genomic aberrations and late recurrence in postmenopausal women with hormone receptor-positive early breast cancer: Results from the SOLE Trial

scientific article published on 20 October 2020

Genotyping concordance in DNA extracted from formalin-fixed paraffin embedded (FFPE) breast tumor and whole blood for pharmacogenetic analyses

scientific article

HER2 status predicts for upfront AI benefit: A TRANS-AIOG meta-analysis of 12,129 patients from ATAC, BIG 1-98 and TEAM with centrally determined HER2.

scientific article published on 08 May 2017

High Expression of FGD3, a Putative Regulator of Cell Morphology and Motility, Is Prognostic of Favorable Outcome in Multiple Cancers

scientific article published on 13 October 2017

Higher prostate-specific antigen levels predict improved survival in patients with hormone-refractory prostate cancer who have skeletal metastases and normal serum alkaline phosphatase

scientific article published on 01 December 2007

Impact of CYP19A1 and ESR1 variants on early-onset side effects during combined endocrine therapy in the TEXT trial

scientific article published on 8 November 2016

Improved adjuvant endocrine therapy for premenopausal women with endocrine responsive disease

scientific article published on 9 June 2015

Improved tumor destruction with arsenic trioxide and radiofrequency ablation in three animal models

scientific article published on 23 May 2006

Independent Validation of EarlyR Gene Signature in BIG 1-98: A Randomized, Double-Blind, Phase III Trial Comparing Letrozole and Tamoxifen as Adjuvant Endocrine Therapy for Postmenopausal Women With Hormone Receptor-Positive, Early Breast Cancer

scientific article published on 16 August 2019

Inherited variation in the androgen pathway is associated with the efficacy of androgen-deprivation therapy in men with prostate cancer

scientific article

Interleukin-2 therapy of metastatic renal cell carcinoma: update of phase III trials

scientific article published on September 2006

Low age adjusted free testosterone levels correlate with poorly differentiated prostate cancer

scientific article published in April 2006

Low-Dose Oral Cyclophosphamide and Methotrexate Maintenance for Hormone Receptor-Negative Early Breast Cancer: International Breast Cancer Study Group Trial 22-00.

scientific article

Metastasis-Free Survival Is a Strong Surrogate of Overall Survival in Localized Prostate Cancer

scientific article published on 10 August 2017

Minimal effect of a low-fat/high soy diet for asymptomatic, hormonally naive prostate cancer patients.

scientific article published in August 2003

Mutational analysis of triple-negative breast cancers within the International Breast Cancer Study Group (IBCSG) Trial 22-00.

scientific article published on 27 March 2018

PI-08 COMBINING URINE PCA3 AND TMPRSS2: ERG TESTS TO REFINE PROSTATE CANCER DETECTION – VALIDATION STUDY AND HEALTH ECONOMIC ANALYSIS

article

Patient-reported outcomes with adjuvant exemestane versus tamoxifen in premenopausal women with early breast cancer undergoing ovarian suppression (TEXT and SOFT): a combined analysis of two phase 3 randomised trials.

scientific article

Pembrolizumab plus trastuzumab in trastuzumab-resistant, advanced, HER2-positive breast cancer (PANACEA): a single-arm, multicentre, phase 1b-2 trial

scientific article published on 11 February 2019

Percent of cores positive for cancer is a better preoperative predictor of cancer recurrence after radical prostatectomy than prostate specific antigen

scientific article

Physician attitudes toward cytotoxic chemotherapy use in patients with advanced prostate carcinoma

scientific article published in May 2003

Physicians' experiences with BRCA1/2 testing in community settings

scientific article

Poor Prognosis After Second Locoregional Recurrences in the CALOR Trial.

scientific article published on 23 September 2016

Potential histologic and molecular predictors of response to temsirolimus in patients with advanced renal cell carcinoma

scientific article published in September 2007

Predicting erectile function following external beam radiation therapy or brachytherapy for prostate cancer using EPIC-CP

scientific article published on 14 April 2018

Predicting response to systemic treatments: learning from the past to plan for the future

scientific article

Predictive value and clinical utility of centrally assessed ER, PgR, and Ki-67 to select adjuvant endocrine therapy for premenopausal women with hormone receptor-positive, HER2-negative early breast cancer: TEXT and SOFT trials.

scientific article published on 22 October 2015

Predictive value of tumor Ki-67 expression in two randomized trials of adjuvant chemoendocrine therapy for node-negative breast cancer.

scientific article published on 29 January 2008

Prevalence of germline variants in inflammatory breast cancer

scientific article published on 01 April 2019

Prognostic and predictive impact of central necrosis and fibrosis in early breast cancer: results from two International Breast Cancer Study Group randomized trials of chemoendocrine adjuvant therapy.

scientific article published on 12 March 2009

Prognostic and predictive value of androgen receptor expression in postmenopausal women with estrogen receptor-positive breast cancer: results from the Breast International Group Trial 1-98

Prognostic and predictive value of centrally reviewed Ki-67 labeling index in postmenopausal women with endocrine-responsive breast cancer: results from Breast International Group Trial 1-98 comparing adjuvant tamoxifen with letrozole

scientific article

Prognostic and predictive value of centrally reviewed expression of estrogen and progesterone receptors in a randomized trial comparing letrozole and tamoxifen adjuvant therapy for postmenopausal early breast cancer: BIG 1-98.

scientific article published on 6 August 2007

Prognostic interaction between expression of p53 and estrogen receptor in patients with node-negative breast cancer: results from IBCSG Trials VIII and IX ⬇️

scientific article published on November 5, 2012

Prostate Specific Antigen Working Group guidelines on prostate specific antigen doubling time

scientific article published on 18 April 2008

Prostate specific antigen doubling time calculation: not as easy as 1, 2, 4.

scientific article published on November 2006

Quality of life under extended continuous versus intermittent adjuvant letrozole in lymph node-positive, early breast cancer patients: the SOLE randomised phase 3 trial

scientific article published on 10 April 2019

Radical prostatectomy lowers plasma vascular endothelial growth factor levels in patients with prostate cancer

scientific article published in February 2004

Re-evaluating adjuvant breast cancer trials: assessing hormone receptor status by immunohistochemical versus extraction assays.

scientific article published in November 2006

Re: Loss of heterozygosity at the CYP2D6 locus in breast cancer: implications for germline pharmacogenetic studies

scientific article published on 26 March 2015

Relationship between serum adiponectin and prostate cancer grade.

scientific article

Relative Effectiveness of Letrozole Compared With Tamoxifen for Patients With Lobular Carcinoma in the BIG 1-98 Trial

scientific article

Reply to F. Tomao et al.

scientific article

Reply to K.-D. Yu et al

scientific article published on 29 April 2019

Reply to L. Moscetti

scientific article published on 17 January 2017

Reply to Y. Zhu et al

scientific article published on 21 December 2017

Response

scientific article published on 03 April 2014

Response to docetaxel/carboplatin-based chemotherapy as first- and second-line therapy in patients with metastatic hormone-refractory prostate cancer

scientific article

Response to low-dose ketoconazole and subsequent dose escalation to high-dose ketoconazole in patients with androgen-independent prostate cancer

scientific article published on 01 September 2006

Response to vinorelbine with or without estramustine as second-line chemotherapy in patients with hormone-refractory prostate cancer

scientific article published on 01 March 2007

Retrospective analysis of the safety and efficacy of interleukin-2 after prior VEGF-targeted therapy in patients with advanced renal cell carcinoma

scientific article published in February 2009

Road Map to Safe and Well-Designed De-escalation Trials of Systemic Adjuvant Therapy for Solid Tumors

scientific article published on 14 October 2020

Serum levels of insulin-like growth factor-1 and insulin-like growth factor-1 binding proteins after radical prostatectomy

scientific article published on 01 November 2002

TOP2A protein by quantitative immunofluorescence as a predictor of response to epirubicin in the neoadjuvant treatment of breast cancer

scientific article

Tailoring Adjuvant Endocrine Therapy for Premenopausal Breast Cancer

scientific article published on 04 June 2018

The Development of Intermediate Clinical Endpoints in Cancer of the Prostate (ICECaP).

scientific article published on 25 September 2015

The Genomic Grade Assay Compared With Ki67 to Determine Risk of Distant Breast Cancer Recurrence

scientific article published on 03 December 2015

The role of mammalian target of rapamycin inhibitors in the treatment of advanced renal cancer

scientific article published on January 2007

Time to prostate-specific antigen nadir independently predicts overall survival in patients who have metastatic hormone-sensitive prostate cancer treated with androgen-deprivation therapy

scientific article published on March 2009

Treatment Efficacy, Adherence, and Quality of Life Among Women Younger Than 35 Years in the International Breast Cancer Study Group TEXT and SOFT Adjuvant Endocrine Therapy Trials

scientific article

Treatment selection for patients with metastatic renal cell carcinoma

scientific article published on May 2009

Treatment-Free Survival: A Novel Outcome Measure of the Effects of Immune Checkpoint Inhibition-A Pooled Analysis of Patients With Advanced Melanoma

scientific article published on 09 September 2019

Treatment-induced symptoms, depression and age as predictors of sexual problems in premenopausal women with early breast cancer receiving adjuvant endocrine therapy

scientific article published on 09 April 2020

Tumor-infiltrating lymphocytes (TILs) are a powerful prognostic marker in patients with triple-negative breast cancer enrolled in the IBCSG phase III randomized clinical trial 22-00.

scientific article published on 02 July 2016

Twelve-Month Estrogen Levels in Premenopausal Women With Hormone Receptor-Positive Breast Cancer Receiving Adjuvant Triptorelin Plus Exemestane or Tamoxifen in the Suppression of Ovarian Function Trial (SOFT): The SOFT-EST Substudy

scientific article published on 4 January 2016

Update on the role of interleukin 2 and other cytokines in the treatment of patients with stage IV renal carcinoma

scientific article published in September 2004

Using clinical trial data to tailor adjuvant treatments for individual patients

scientific article

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