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List of works by Samir El Andaloussi

A CRISPR-Cas9-based reporter system for single-cell detection of extracellular vesicle-mediated functional transfer of RNA

scientific article published on 28 February 2020

A stearylated CPP for delivery of splice correcting oligonucleotides using a non-covalent co-incubation strategy

scientific article published on 6 December 2008

Advances in therapeutic applications of extracellular vesicles

scientific article published on 01 May 2019

Applying extracellular vesicles based therapeutics in clinical trials - an ISEV position paper.

scientific article

Assessing the delivery efficacy and internalization route of cell-penetrating peptides

scientific article published on January 2007

Assessing the uptake kinetics and internalization mechanisms of cell-penetrating peptides using a quenched fluorescence assay

scientific article

Autologous Peripheral Blood Mononuclear Cells as Treatment in Refractory Acute Respiratory Distress Syndrome.

scientific article published on 28 November 2015

C9orf72 and RAB7L1 regulate vesicle trafficking in amyotrophic lateral sclerosis and frontotemporal dementia

scientific article

Cell-penetrating peptides-based strategies for the delivery of splice redirecting antisense oligonucleotides

scientific article

Cells release subpopulations of exosomes with distinct molecular and biological properties

scientific article published on 2 March 2016

Cellular internalization kinetics of (luciferin-)cell-penetrating peptide conjugates

scientific article published on 01 September 2010

Chemically modified cell-penetrating peptides for the delivery of nucleic acids

scientific article

Comprehensive RNA-Sequencing Analysis in Serum and Muscle Reveals Novel Small RNA Signatures with Biomarker Potential for DMD

scientific article published on 17 August 2018

Considerations and Implications in the Purification of Extracellular Vesicles - A Cautionary Tale

scientific article published on 18 October 2019

Correction to: Isolation and Characterization of Extracellular Vesicles from Keratinocyte Cultures

scientific article published on 01 January 2020

Delivery is key: lessons learnt from developing splice-switching antisense therapies

scientific article

Delivery of nucleic acids with a stearylated (RxR)4 peptide using a non-covalent co-incubation strategy

scientific article

Design and application of bispecific splice-switching oligonucleotides

scientific article published on February 2014

Development of bis-locked nucleic acid (bisLNA) oligonucleotides for efficient invasion of supercoiled duplex DNA.

scientific article published on 23 January 2013

Diaminopropionic acid lipopeptides: characterization studies of polyplexes aimed at pDNA delivery.

scientific article

Disentangling the Amyloid Pathways: A Mechanistic Approach to Etiology

scientific article published on 21 April 2020

Elucidating cell-penetrating peptide mechanisms of action for membrane interaction, cellular uptake, and translocation utilizing the hydrophobic counter-anion pyrenebutyrate

scientific article published on 29 September 2009

Engineered extracellular vesicle decoy receptor-mediated modulation of the IL6 trans-signalling pathway in muscle

scientific article published on 05 October 2020

Evidence-Based Clinical Use of Nanoscale Extracellular Vesicles in Nanomedicine

scientific article

Exosomes for targeted siRNA delivery across biological barriers.

scientific article published on 18 August 2012

Expression Analysis in Multiple Muscle Groups and Serum Reveals Complexity in the MicroRNA Transcriptome of the mdx Mouse with Implications for Therapy ⬇️

scientific article published on August 14, 2012

Extracellular vesicle in vivo biodistribution is determined by cell source, route of administration and targeting.

scientific article published on 20 April 2015

Extracellular vesicles in neurodegenerative disease - pathogenesis to biomarkers.

scientific article published on 13 May 2016

Four Novel Splice-Switch Reporter Cell Lines: Distinct Impact of Oligonucleotide Chemistry and Delivery Vector on Biological Activity.

scientific article

From gut to brain: bioencapsulated therapeutic protein reduces amyloid load upon oral delivery

scientific article published on March 2014

Functional Delivery of Lipid-Conjugated siRNA by Extracellular Vesicles.

scientific article published on 6 April 2017

Functional correction in mouse models of muscular dystrophy using exon-skipping tricyclo-DNA oligomers.

scientific article published on 2 February 2015

Functional extracellular vesicles aplenty

scientific article published on 01 January 2020

GAPDH controls extracellular vesicle biogenesis and enhances the therapeutic potential of EV mediated siRNA delivery to the brain

scientific article published on 18 November 2021

Heterogeneity and interplay of the extracellular vesicle small RNA transcriptome and proteome

scientific article published in Scientific Reports

How much dystrophin is enough: the physiological consequences of different levels of dystrophin in the mdx mouse

scientific article published in May 2015

In Vivo Effects of Mesenchymal Stromal Cells in Two Patients With Severe Acute Respiratory Distress Syndrome

scholarly article published in Stem Cells Translational Medicine

In Vivo Effects of Mesenchymal Stromal Cells in Two Patients With Severe Acute Respiratory Distress Syndrome.

scientific article

Insights into the cellular trafficking of splice redirecting oligonucleotides complexed with chemically modified cell-penetrating peptides

scientific article published on 20 April 2011

Isolation and Characterization of Extracellular Vesicles from Keratinocyte Cultures

scientific article published on 01 January 2020

Isolation of Exosomes from Blood Plasma: Qualitative and Quantitative Comparison of Ultracentrifugation and Size Exclusion Chromatography Methods

scientific article published on 21 December 2015

Label-Free Surface Protein Profiling of Extracellular Vesicles by an Electrokinetic Sensor

scientific article published on 07 May 2019

Lipid-based Transfection Reagents Exhibit Cryo-induced Increase in Transfection Efficiency.

scientific article

Micro-minicircle Gene Therapy: Implications of Size on Fermentation, Complexation, Shearing Resistance, and Expression.

scientific article published on 07 January 2014

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

scientific article published on 23 November 2018

Modulating Anti-MicroRNA-21 Activity and Specificity Using Oligonucleotide Derivatives and Length Optimization

scientific article published on 7 February 2012

Multi-level omics analysis in a murine model of dystrophin loss and therapeutic restoration.

scientific article

Mutation-independent proteomic signatures of pathological progression in murine models of Duchenne muscular dystrophy

scientific article published on 29 September 2020

Natural Antisense Makes Sense for Gene-specific Activation in Brain.

scientific article published on 15 May 2012

Novel Peptide-dendrimer/Lipid/Oligonucleotide Ternary Complexes for Efficient Cellular Uptake and Improved Splice-Switching Activity

scientific article published on 04 September 2018

Novel endosomolytic compounds enable highly potent delivery of antisense oligonucleotides

scientific article published on 01 March 2022

Novel viral vectors utilizing intron splice-switching to activate genome rescue, expression and replication in targeted cells

scientific article

Peptide nanoparticle delivery of charge-neutral splice-switching morpholino oligonucleotides.

scientific article published on 16 January 2015

Peptide-based matrices as drug delivery vehicles

scientific article published on January 2010

Peptide-mediated Cell and In Vivo Delivery of Antisense Oligonucleotides and siRNA.

scientific article published on 12 June 2012

Peptides for nucleic acid delivery

scientific article

Publisher Correction: A CRISPR-Cas9-based reporter system for single-cell detection of extracellular vesicle-mediated functional transfer of RNA

scientific article published on 31 March 2020

Quantification of extracellular vesicles in vitro and in vivo using sensitive bioluminescence imaging

scientific article published on 21 August 2020

Reproducible and scalable purification of extracellular vesicles using combined bind-elute and size exclusion chromatography.

scientific article published on 14 September 2017

Salivary extracellular vesicles inhibit Zika virus but not SARS-CoV-2 infection

scientific article published on 24 August 2020

Selective release of muscle-specific, extracellular microRNAs during myogenic differentiation

scientific article (publication date: 15 September 2016)

Serum-free culture alters the quantity and protein composition of neuroblastoma-derived extracellular vesicles

scientific article

Size matters: Functional differences of small extracellular vesicle subpopulations in cardiac repair responses

scientific article published in 2024

Smad‑binding decoy reduces extracellular matrix expression in human hypertrophic scar fibroblasts

scientific article published on 29 September 2020

Small RNA-Mediated Epigenetic Myostatin Silencing.

scientific article published on 15 May 2012

Solid formulation of cell-penetrating peptide nanocomplexes with siRNA and their stability in simulated gastric conditions.

scientific article

Splice-correcting oligonucleotides restore BTK function in X-linked agammaglobulinemia model

scientific article

Splice-correction strategies for treatment of X-linked agammaglobulinemia.

scientific article

Splice-switching efficiency and specificity for oligonucleotides with locked nucleic acid monomers

scientific article published on 01 June 2008

Sugar and Polymer Excipients Enhance Uptake and Splice-Switching Activity of Peptide-Dendrimer/Lipid/Oligonucleotide Formulations

scientific article published on 09 December 2019

Synthetic SiRNA Delivery: Progress and Prospects

scientific article published on January 2016

Systematic Methodological Evaluation of a Multiplex Bead-Based Flow Cytometry Assay for Detection of Extracellular Vesicle Surface Signatures.

scientific article

Systematic characterization of extracellular vesicle sorting domains and quantification at the single molecule - single vesicle level by fluorescence correlation spectroscopy and single particle imaging

scientific article published on 18 September 2019

Tangential Flow Filtration with or Without Subsequent Bind-Elute Size Exclusion Chromatography for Purification of Extracellular Vesicles

scientific article published on 01 January 2019

The biogenesis and characterization of mammalian microRNAs of mirtron origin.

scientific article published on 13 September 2011

The viral protein corona directs viral pathogenesis and amyloid aggregation

scientific article published on 27 May 2019

Translocation-generated ITK-FER and ITK-SYK fusions induce STAT3 phosphorylation and CD69 expression

scientific article published on 11 September 2018

UFLC-derived CSF extracellular vesicle origin and proteome

scientific article published on 10 December 2018

Ultrafiltration with size-exclusion liquid chromatography for high yield isolation of extracellular vesicles preserving intact biophysical and functional properties

scientific article published on 4 February 2015

mRNA and microRNA transcriptomics analyses in a murine model of dystrophin loss and therapeutic restoration.

scientific article published on 02 December 2015

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