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List of works by Marina A Zenkova

'Dual' peptidyl-oligonucleotide conjugates: Role of conformational flexibility in catalytic cleavage of RNA.

scientific article published on 3 October 2016

2'-O-methyl-modified anti-MDR1 fork-siRNA duplexes exhibiting high nuclease resistance and prolonged silencing activity

scientific article published on 28 October 2010

42- and 63-bp anti-MDR1-siRNAs bearing 2'-OMe modifications in nuclease-sensitive sites induce specific and potent gene silencing

scientific article published on 20 February 2014

82 Structural aspects of non-enzymatic recombination in viral RNA.

scientific article published on May 2015

A novel expression cassette delivers efficient production of exclusively tetrameric human butyrylcholinesterase with improved pharmacokinetics for protection against organophosphate poisoning.

scientific article published on 31 July 2015

Affinity modification of 80S ribosomes from human placenta with mRNA analogs--derivatives of oligouridylates with alkylating groups at the 3'-end

scientific article published on 01 July 1992

Alteration of the exDNA profile in blood serum of LLC-bearing mice under the decrease of tumour invasion potential by bovine pancreatic DNase I treatment

scientific article

Animal model of drug-resistant tumor progression

scientific article published on 01 December 2006

Antitumor and Antimetastatic Effect of Small Immunostimulatory RNA against B16 Melanoma in Mice

scientific article

Antitumour Activity of the Ribonuclease Binase from Bacillus pumilus in the RLS40 Tumour Model Is Associated with the Reorganisation of the miRNA Network and Reversion of Cancer-Related Cascades to Normal Functioning

scientific article published on 02 November 2020

Artificial ribonucleases inactivate a wide range of viruses using their ribonuclease, membranolytic, and chaotropic-like activities.

scientific article published on 27 July 2016

Asthma and Post-Asthmatic Fibrosis: A Search for New Promising Molecular Markers of Transition from Acute Inflammation to Pulmonary Fibrosis

scientific article published on 28 April 2022

Autocrine-based selection of ligands for personalized CAR-T therapy of lymphoma

scientific article published on 14 November 2018

Carrier-free cellular uptake and the gene-silencing activity of the lipophilic siRNAs is strongly affected by the length of the linker between siRNA and lipophilic group

scientific article published on 10 November 2011

Catalytic Knockdown of miR-21 by Artificial Ribonuclease: Biological Performance in Tumor Model

scientific article published on 08 August 2019

Chemical modification of siRNA.

scientific article published on April 2010

Cholesterol-Containing Nuclease-Resistant siRNA Accumulates in Tumors in a Carrier-free Mode and Silences MDR1 Gene.

scientific article published on 03 January 2017

Comparison of behaviour in different liquids and in cells of gold nanorods and spherical nanoparticles modified by linear polyethyleneimine and bovine serum albumin

scientific article published on July 2014

Correction to Peptidyl-Oligonucleotide Conjugates Demonstrate Efficient Cleavage of RNA in a Sequence-Specific Manner

scientific article

Covalently attached oligodeoxyribonucleotides induce RNase activity of a short peptide and modulate its base specificity.

scientific article

Cyano Enone-Bearing Triterpenoid Soloxolone Methyl Inhibits Epithelial-Mesenchymal Transition of Human Lung Adenocarcinoma Cells In Vitro and Metastasis of Murine Melanoma In Vivo

scientific article published on 14 December 2020

Cytochalasin-B-Inducible Nanovesicle Mimics of Natural Extracellular Vesicles That Are Capable of Nucleic Acid Transfer

scientific article published on 01 November 2019

Deep insights into the response of human cervical carcinoma cells to a new cyano enone-bearing triterpenoid soloxolone methyl: a transcriptome analysis

scientific article published on 03 September 2019

Design of nuclease-resistant fork-like small interfering RNA (fsiRNA).

scientific article published in January 2013

Design, RNA cleavage and antiviral activity of new artificial ribonucleases derived from mono-, di- and tripeptides connected by linkers of different hydrophobicity

scientific article

Design, synthesis and transfection efficiency of a novel redox-sensitive polycationic amphiphile

scientific article published on 2 November 2016

Downregulation of PGY1/MDR1 mRNA level in human KB cells by antisense oligonucleotide conjugates. RNA accessibility in vitro and intracellular antisense activity.

scientific article

Dual Effect of Soloxolone Methyl on LPS-Induced Inflammation In Vitro and In Vivo

scientific article published on 23 October 2020

Dual miRNases for Triple Incision of miRNA Target: Design Concept and Catalytic Performance

scientific article published on 25 May 2020

Effective cleavage of structured RNAs by tandems of 10-23 DNAzymes with 3'-modified oligo(2'-O-methylribonucleotide)-effectors.

scientific article

Enhanced RNA cleavage within bulge-loops by an artificial ribonuclease

scientific article

Enhanced cellular binding of concatemeric oligonucleotide complexes

scientific article published on March 2006

Erratum to: Oncolytic virus efficiency inhibited growth of tumour cells with multiple drug resistant phenotype in vivo and in vitro.

scientific article published on 27 September 2016

Female scent signals enhance the resistance of male mice to influenza

scientific article

Fluorophore Labeling Affects the Cellular Accumulation and Gene Silencing Activity of Cholesterol-Modified siRNAs In Vitro

scientific article published on 18 December 2018

Functional topography of human ribosomes as studied by affinity labeling with reactive mRNA analogs ⬇️

scientific article published on 01 April 1992

G-specific RNA-cleaving conjugates of short peptides and oligodeoxyribonucleotides.

scientific article

Human Recombinant DNase I (Pulmozyme®) Inhibits Lung Metastases in Murine Metastatic B16 Melanoma Model That Correlates with Restoration of the DNase Activity and the Decrease SINE/LINE and c-Myc Fragments in Blood Cell-Free DNA

scientific article published on 09 November 2021

Hybridization of antisense oligonucleotides with alpha-sarcin loop region of Escherichia coli 23S rRNA.

scientific article

Identification of Novel Core Genes Involved in Malignant Transformation of Inflamed Colon Tissue Using a Computational Biology Approach and Verification in Murine Models

scientific article published in 2023

Immunostimulating RNA Delivered by P1500 PEGylated Cationic Liposomes Limits Influenza Infection in C57Bl/6 Mice

scientific article published on 14 September 2020

Immunotherapy of hepatocellular carcinoma with small double-stranded RNA.

scientific article

Inactivation of a non-enveloped RNA virus by artificial ribonucleases: honey bees and acute bee paralysis virus as a new experimental model for in vivo antiviral activity assessment.

scientific article published on 22 June 2011

Inactivation of the tick-borne encephalitis virus by RNA-cleaving compounds

scientific article published on 31 December 2011

Influenza virus inactivated by artificial ribonucleases as a prospective killed virus vaccine

scientific article published on 2 March 2012

Inhibition of metastasis development by daily administration of ultralow doses of RNase A and DNase I.

scientific article

Isolation of ribosomal subunits containing intact rRNA from human placenta: Estimation of functional activity of 80S ribosomes ⬇️

scientific article published on 01 November 1991

Mesyl phosphoramidate backbone modified antisense oligonucleotides targeting miR-21 with enhanced in vivo therapeutic potency

scientific article published on 07 December 2020

MicroRNA drop in the bloodstream and microRNA boost in the tumour caused by treatment with ribonuclease A leads to an attenuation of tumour malignancy

scientific article

Modified siRNA effectively silence inducible immunoproteasome subunits in NSO cells

scientific article published on March 2016

Modulation of Tumour-Related Signaling Pathways by Natural Pentacyclic Triterpenoids and their Semisynthetic Derivatives

scientific article published on 12 January 2017

Molecular Mechanism of the Antiproliferative Activity of Short Immunostimulating dsRNA

scientific article published on 20 December 2019

Morphologic Changes in the Tumor and Liver in Mice with Transplanted RLS40 Lymphosarcoma during Increase of Its Drug Resistance ⬇️

scientific article published on 01 August 2010

Multicomponent mannose-containing liposomes efficiently deliver RNA in murine immature dendritic cells and provide productive anti-tumour response in murine melanoma model

scientific article

Non-enzymatic recombination of RNA: Ligation in loops.

scientific article

Non-enzymatic template-directed recombination of RNAs.

scientific article published on 21 April 2009

Nonenzymatic recombination of RNA: possible mechanism for the formation of novel sequences

scientific article published on 01 April 2007

Novel 3'-Substituted-1',2',4'-Oxadiazole Derivatives of 18βH-Glycyrrhetinic Acid and Their O-Acylated Amidoximes: Synthesis and Evaluation of Antitumor and Anti-Inflammatory Potential In Vitro and In Vivo ⬇️

scientific article published on 15 May 2020

Novel 5'-Norcarbocyclic Derivatives of Bicyclic Pyrrolo- and Furano[2,3-d]Pyrimidine Nucleosides

scientific article published on 16 October 2018

Novel Derivatives of Deoxycholic Acid Bearing Linear Aliphatic Diamine and Aminoalcohol Moieties and their Cyclic Analogs at the C3 Position: Synthesis and Evaluation of Their In Vitro Antitumor Potential

scientific article published on 21 July 2019

Novel PEGylated Liposomes Enhance Immunostimulating Activity of isRNA

scientific article published on 27 November 2018

Novel cationic liposomes provide highly efficient delivery of DNA and RNA into dendritic cell progenitors and their immature offsets

scientific article

Novel cholesterol spermine conjugates provide efficient cellular delivery of plasmid DNA and small interfering RNA.

scientific article published on 25 November 2011

Novel cholesterol-based cationic lipids for gene delivery.

scientific article published on November 2009

Novel derivatives of deoxycholic acid bearing aliphatic or cyclic diamine moieties at the C-3 position: Synthesis and evaluation of anti-proliferative activity

scientific article

Novel multifunctional hybrids of single-walled carbon nanotubes with nucleic acids: synthesis and interactions with living cells

scientific article published on 14 January 2014

Nuclease-resistant 63-bp trimeric siRNAs simultaneously silence three different genes in tumor cells.

scientific article published on 2 December 2017

Oncolytic virus efficiency inhibited growth of tumour cells with multiple drug resistant phenotype in vivo and in vitro

scientific article published on 18 August 2016

Peptidyl-oligonucleotide conjugates demonstrate efficient cleavage of RNA in a sequence-specific manner

scientific article published on 21 May 2015

Prophylactic Dendritic Cell-Based Vaccines Efficiently Inhibit Metastases in Murine Metastatic Melanoma

scientific article published on September 2015

RNA knockdown by synthetic peptidyl-oligonucleotide ribonucleases: behavior of recognition and cleavage elements under physiological conditions

scientific article published on 06 April 2020

RNA-hydrolyzing activity of human serum albumin and its recombinant analogue.

scientific article published on 4 January 2010

Ribonuclease binase inhibits primary tumor growth and metastases via apoptosis induction in tumor cells

scientific article published on 10 June 2013

Selective protection of nuclease-sensitive sites in siRNA prolongs silencing effect

scientific article published on June 2009

Selectivity of the sequence specific alkylation of high molecular weight RNA ⬇️

scientific article published on January 1, 1991

Sequence-specific artificial ribonucleases. I. Bis-imidazole-containing oligonucleotide conjugates prepared using precursor-based strategy

scientific article

Short double-stranded RNA with immunostimulatory activity: sequence dependence

scientific article

Silencing activity of 2′-O-methyl modified anti-MDR1 siRNAs with mismatches in the central part of the duplexes

scientific article published on 23 June 2011

Silencing of Inducible Immunoproteasome Subunit Expression by Chemically Modified siRNA and shRNA.

scientific article published on 28 June 2016

Site-selective artificial ribonucleases: oligonucleotide conjugates containing multiple imidazole residues in the catalytic domain.

scientific article published on 25 September 2011

Soloxolone methyl inhibits influenza virus replication and reduces virus-induced lung inflammation

scientific article published on 25 October 2017

Spacer structure and hydrophobicity influences transfection activity of novel polycationic gemini amphiphiles.

scientific article published on 10 June 2017

Specifically activated dendritic cells—Cell-based vaccine against lymphosarcoma exhibiting multiple drug resistance phenotype ⬇️

scientific article published on September 1, 2009

Strict conformational demands of RNA cleavage in bulge-loops created by peptidyl-oligonucleotide conjugates

scientific article published on 03 October 2020

Structure-transfection activity relationships in a series of novel cationic lipids with heterocyclic head-groups

scientific article published on November 2013

Synthesis and biological activity of novel deoxycholic acid derivatives

scientific article published on 13 May 2015

Synthesis and delivery activity of new cationic cholesteryl glucosides.

scientific article published on 17 September 2010

Synthesis and evaluation of antitumor, anti-inflammatory and analgesic activity of novel deoxycholic acid derivatives bearing aryl- or hetarylsulfanyl moieties at the C-3 position

scientific article published on 5 September 2017

Synthesis and pro-apoptotic activity of novel glycyrrhetinic acid derivatives.

scientific article published on 15 February 2011

Synthesis of novel 2-cyano substituted glycyrrhetinic acid derivatives as inhibitors of cancer cells growth and NO production in LPS-activated J-774 cells.

scientific article

Targeted delivery of nucleic acids into xenograft tumors mediated by novel folate-equipped liposomes

scientific article published on 18 November 2017

Targeting Circulating SINEs and LINEs with DNase I Provides Metastases Inhibition in Experimental Tumor Models

scientific article published on 08 February 2020

The Toxic Effects of Polychemotherapy onto the Liver Are Accelerated by the Upregulated MDR of Lymphosarcoma.

scientific article published on 29 November 2012

The siRNA targeted to mdr1b and mdr1a mRNAs in vivo sensitizes murine lymphosarcoma to chemotherapy

scientific article

The systemic tumor response to RNase A treatment affects the expression of genes involved in maintaining cell malignancy

scientific article published on 12 August 2017

Transfection efficiency of 25-kDa PEI-cholesterol conjugates with different levels of modification

scientific article

Transport Oligonucleotides-A Novel System for Intracellular Delivery of Antisense Therapeutics

scientific article published on 11 August 2020

Trioxolone Methyl, a Novel Cyano Enone-Bearing 18βH-Glycyrrhetinic Acid Derivative, Ameliorates Dextran Sulphate Sodium-Induced Colitis in Mice

scientific article published on 21 May 2020

Virtual screening, synthesis and biological evaluation of DNA intercalating antiviral agents

scientific article published on 13 June 2017

[Complementary addressed alkylation of 16S rRNA of Escherichia coli by 2',3'-O-[4-N-methyl-N-(2-chloroethyl)-amino]benzylidene derivatives of oligodeoxyribonucleotides. V. Study of the factors affecting selectivity of modification]

scientific article published on 01 April 1991

miRNases: Novel peptide-oligonucleotide bioconjugates that silence miR-21 in lymphosarcoma cells.

scientific article published on 13 January 2017

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