List of works - Yoshio Koyanagi

A Naturally Occurring Domestic Cat APOBEC3 Variant Confers Resistance to Feline Immunodeficiency Virus Infection.

scientific article published on 21 October 2015

A conflict of interest: the evolutionary arms race between mammalian APOBEC3 and lentiviral Vif.

scientific article

A duodenally absorbable CXC chemokine receptor 4 antagonist, KRH-1636, exhibits a potent and selective anti-HIV-1 activity

scholarly article

A high excision potential of TALENs for integrated DNA of HIV-based lentiviral vector

scientific article published on 17 March 2015

A lentiviral cDNA library employing lambda recombination used to clone an inhibitor of human immunodeficiency virus type 1-induced cell death

scientific article

A naturally occurring bovine APOBEC3 confers resistance to bovine lentiviruses: implication for the co-evolution of bovids and their lentiviruses

scientific article

A novel animal model of Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis in humanized mice

scientific article

A novel protective MHC-I haplotype not associated with dominant Gag-specific CD8+ T-cell responses in SIVmac239 infection of Burmese rhesus macaques

scientific article

A role for gorilla APOBEC3G in shaping lentivirus evolution including transmission to humans

scientific article published on 10 September 2020

APOBEC1-mediated editing and attenuation of herpes simplex virus 1 DNA indicate that neurons have an antiviral role during herpes simplex encephalitis

scientific article

APOBEC3D and APOBEC3F potently promote HIV-1 diversification and evolution in humanized mouse model

scientific article

Anti-V3 humanized antibody KD-247 effectively suppresses ex vivo generation of human immunodeficiency virus type 1 and affords sterile protection of monkeys against a heterologous simian/human immunodeficiency virus infection

scientific article

Antithetic effect of interferon-α on cell-free and cell-to-cell HIV-1 infection

scientific article published on 25 April 2022

Characterization of RyDEN (C19orf66) as an Interferon-Stimulated Cellular Inhibitor against Dengue Virus Replication

scientific journal article

Characterization of red-capped mangabey tetherin: implication for the co-evolution of primates and their lentiviruses

scientific article

Coevolutionary dynamics between tribe Cercopithecini tetherins and their lentiviruses.

scientific article

Correction: HIV-1 competition experiments in humanized mice show that APOBEC3H imposes selective pressure and promotes virus adaptation

scientific article published on 7 September 2017

Death ligand-mediated apoptosis in HIV infection

scientific article

Development of human Graafian follicles following transplantation of human ovarian tissue into NOD/SCID/gammac null mice

scientific article published on 01 December 2008

Different effects of two mutations on the infectivity of Ebola virus glycoprotein in nine mammalian species

scientific article published on 4 January 2018

Down-modulation of primate lentiviral receptors by Nef proteins of simian immunodeficiency virus (SIV) of chimpanzees (SIVcpz) and related SIVs: implication for the evolutionary event at the emergence of SIVcpz

scientific article published on 3 June 2015

Experimental evaluation of the zoonotic infection potency of simian retrovirus type 4 using humanized mouse model.

scientific article

Feline Immunodeficiency Virus Evolutionarily Acquires Two Proteins, Vif and Protease, Capable of Antagonizing Feline APOBEC3

scientific article

Functional disruption of the moloney murine leukemia virus preintegration complex by vaccinia-related kinases

scientific article

Functional mutations in spike glycoprotein of Zaire ebolavirus associated with an increase in infection efficiency

scientific article published on 13 January 2017

HIV-1 Vpr accelerates viral replication during acute infection by exploitation of proliferating CD4+ T cells in vivo

scientific article

HIV-1 competition experiments in humanized mice show that APOBEC3H imposes selective pressure and promotes virus adaptation

scientific article

HIV-1 tracing method of systemic viremia in vivo using an artificially mutated virus pool

scientific article published on 24 November 2020

HIV-1 viral infectivity factor interacts with TP53 to induce G2 cell cycle arrest and positively regulate viral replication.

scientific article published on 11 November 2010

Harnessing the CRISPR/Cas9 system to disrupt latent HIV-1 provirus

scientific article

Host factor SAMHD1 restricts DNA viruses in non-dividing myeloid cells

scientific article

Human-Specific Adaptations in Vpu Conferring Anti-tetherin Activity Are Critical for Efficient Early HIV-1 Replication In Vivo

scientific article published in January 2018

Identification of Amino Acids in the Human Tetherin Transmembrane Domain Responsible for HIV-1 Vpu Interaction and Susceptibility ⬇️

scientific article published on November 10, 2010

Identification of the P-TEFb complex-interacting domain of Brd4 as an inhibitor of HIV-1 replication by functional cDNA library screening in MT-4 cells

scientific article

Immunohistochemical localization of steroidogenic enzymes in human follicle following xenotransplantation of the human ovarian cortex into NOD-SCID mice

scientific article published in May 2003

Impacts of humanized mouse models on the investigation of HIV-1 infection: illuminating the roles of viral accessory proteins in vivo

scientific article

Improving the estimation of the death rate of infected cells from time course data during the acute phase of virus infections: application to acute HIV-1 infection in a humanized mouse model.

scientific article

Lack of association between intact/deletion polymorphisms of the APOBEC3B gene and HIV-1 risk

scientific article

NOD/SCID/gamma(c)(null) mouse: an excellent recipient mouse model for engraftment of human cells

scientific article (publication date: November 2002)

Pandemic HIV-1 Vpu overcomes intrinsic herd immunity mediated by tetherin.

scientific article

Phosphorylation of herpes simplex virus 1 dUTPase regulates viral virulence and genome integrity by compensating for low cellular dUTPase activity in the central nervous system

scientific article

Potent anti-R5 human immunodeficiency virus type 1 effects of a CCR5 antagonist, AK602/ONO4128/GW873140, in a novel human peripheral blood mononuclear cell nonobese diabetic-SCID, interleukin-2 receptor gamma-chain-knocked-out AIDS mouse model.

scientific article

Quantification of deaminase activity-dependent and -independent restriction of HIV-1 replication mediated by APOBEC3F and APOBEC3G through experimental-mathematical investigation

scientific article

Rapid Tumor Formation of Human T-Cell Leukemia Virus Type 1-Infected Cell Lines in Novel NOD-SCID/γcnullMice: Suppression by an Inhibitor against NF-κB ⬇️

scientific article published on May 1, 2003

Remarkable lethal G-to-A mutations in vif-proficient HIV-1 provirus by individual APOBEC3 proteins in humanized mice

scientific article

Reproduction of menstrual changes in transplanted human endometrial tissue in immunodeficient mice

scientific article

Small intestine CD4+ cell reduction and enteropathy in simian/human immunodeficiency virus KS661-infected rhesus macaques in the presence of low viral load

scientific article

Small ruminant lentiviral Vif proteins commonly utilize cyclophilin A, an evolutionarily and structurally conserved protein, to degrade ovine and caprine APOBEC3 proteins

scientific article published on 19 May 2016

Solution RNA structures of the HIV-1 dimerization initiation site in the kissing-loop and extended-duplex dimers

scientific article

Species-specific differences in the ability of feline lentiviral Vif to degrade feline APOBEC3 proteins

scientific article published on 03 March 2016

Spirodiketopiperazine-based CCR5 inhibitor which preserves CC-chemokine/CCR5 interactions and exerts potent activity against R5 human immunodeficiency virus type 1 in vitro

scientific article

T cell-based functional cDNA library screening identified SEC14-like 1a carboxy-terminal domain as a negative regulator of human immunodeficiency virus replication

scientific article

The hematopoietic cell-specific Rho GTPase inhibitor ARHGDIB/D4GDI limits HIV type 1 replication

scientific article

Tumor necrosis factor-related apoptosis-inducing ligand induces neuronal death in a murine model of HIV central nervous system infection

scientific article

Various plus unique: Viral protein U as a plurifunctional protein for HIV-1 replication

scientific article published on January 2017

Vif determines the requirement for CBF-β in APOBEC3 degradation

scientific article

Vpu Augments the Initial Burst Phase of HIV-1 Propagation and Downregulates BST2 and CD4 in Humanized Mice ⬇️

scientific article published on February 22, 2012

Vpu and BST2: Still Not There Yet? ⬇️

scientific article published on April 9, 2012

List of works by Yoshio Koyanagi

A Naturally Occurring Domestic Cat APOBEC3 Variant Confers Resistance to Feline Immunodeficiency Virus Infection.

A conflict of interest: the evolutionary arms race between mammalian APOBEC3 and lentiviral Vif.

A duodenally absorbable CXC chemokine receptor 4 antagonist, KRH-1636, exhibits a potent and selective anti-HIV-1 activity

A high excision potential of TALENs for integrated DNA of HIV-based lentiviral vector

A lentiviral cDNA library employing lambda recombination used to clone an inhibitor of human immunodeficiency virus type 1-induced cell death

A naturally occurring bovine APOBEC3 confers resistance to bovine lentiviruses: implication for the co-evolution of bovids and their lentiviruses

A novel animal model of Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis in humanized mice

A novel protective MHC-I haplotype not associated with dominant Gag-specific CD8+ T-cell responses in SIVmac239 infection of Burmese rhesus macaques

A role for gorilla APOBEC3G in shaping lentivirus evolution including transmission to humans

APOBEC1-mediated editing and attenuation of herpes simplex virus 1 DNA indicate that neurons have an antiviral role during herpes simplex encephalitis

APOBEC3D and APOBEC3F potently promote HIV-1 diversification and evolution in humanized mouse model

Anti-V3 humanized antibody KD-247 effectively suppresses ex vivo generation of human immunodeficiency virus type 1 and affords sterile protection of monkeys against a heterologous simian/human immunodeficiency virus infection

Antithetic effect of interferon-α on cell-free and cell-to-cell HIV-1 infection

Characterization of RyDEN (C19orf66) as an Interferon-Stimulated Cellular Inhibitor against Dengue Virus Replication

Characterization of red-capped mangabey tetherin: implication for the co-evolution of primates and their lentiviruses

Coevolutionary dynamics between tribe Cercopithecini tetherins and their lentiviruses.

Correction: HIV-1 competition experiments in humanized mice show that APOBEC3H imposes selective pressure and promotes virus adaptation

Death ligand-mediated apoptosis in HIV infection

Development of human Graafian follicles following transplantation of human ovarian tissue into NOD/SCID/gammac null mice

Different effects of two mutations on the infectivity of Ebola virus glycoprotein in nine mammalian species

Down-modulation of primate lentiviral receptors by Nef proteins of simian immunodeficiency virus (SIV) of chimpanzees (SIVcpz) and related SIVs: implication for the evolutionary event at the emergence of SIVcpz

Experimental evaluation of the zoonotic infection potency of simian retrovirus type 4 using humanized mouse model.

Feline Immunodeficiency Virus Evolutionarily Acquires Two Proteins, Vif and Protease, Capable of Antagonizing Feline APOBEC3

Functional disruption of the moloney murine leukemia virus preintegration complex by vaccinia-related kinases

Functional mutations in spike glycoprotein of Zaire ebolavirus associated with an increase in infection efficiency

HIV-1 Vpr accelerates viral replication during acute infection by exploitation of proliferating CD4+ T cells in vivo

HIV-1 competition experiments in humanized mice show that APOBEC3H imposes selective pressure and promotes virus adaptation

HIV-1 tracing method of systemic viremia in vivo using an artificially mutated virus pool

HIV-1 viral infectivity factor interacts with TP53 to induce G2 cell cycle arrest and positively regulate viral replication.

Harnessing the CRISPR/Cas9 system to disrupt latent HIV-1 provirus

Host factor SAMHD1 restricts DNA viruses in non-dividing myeloid cells

Human-Specific Adaptations in Vpu Conferring Anti-tetherin Activity Are Critical for Efficient Early HIV-1 Replication In Vivo

Identification of Amino Acids in the Human Tetherin Transmembrane Domain Responsible for HIV-1 Vpu Interaction and Susceptibility ⬇️

Identification of the P-TEFb complex-interacting domain of Brd4 as an inhibitor of HIV-1 replication by functional cDNA library screening in MT-4 cells

Immunohistochemical localization of steroidogenic enzymes in human follicle following xenotransplantation of the human ovarian cortex into NOD-SCID mice

Impacts of humanized mouse models on the investigation of HIV-1 infection: illuminating the roles of viral accessory proteins in vivo

Improving the estimation of the death rate of infected cells from time course data during the acute phase of virus infections: application to acute HIV-1 infection in a humanized mouse model.

Lack of association between intact/deletion polymorphisms of the APOBEC3B gene and HIV-1 risk

NOD/SCID/gamma(c)(null) mouse: an excellent recipient mouse model for engraftment of human cells

Pandemic HIV-1 Vpu overcomes intrinsic herd immunity mediated by tetherin.

Phosphorylation of herpes simplex virus 1 dUTPase regulates viral virulence and genome integrity by compensating for low cellular dUTPase activity in the central nervous system

Potent anti-R5 human immunodeficiency virus type 1 effects of a CCR5 antagonist, AK602/ONO4128/GW873140, in a novel human peripheral blood mononuclear cell nonobese diabetic-SCID, interleukin-2 receptor gamma-chain-knocked-out AIDS mouse model.

Quantification of deaminase activity-dependent and -independent restriction of HIV-1 replication mediated by APOBEC3F and APOBEC3G through experimental-mathematical investigation

Rapid Tumor Formation of Human T-Cell Leukemia Virus Type 1-Infected Cell Lines in Novel NOD-SCID/γcnullMice: Suppression by an Inhibitor against NF-κB ⬇️

Remarkable lethal G-to-A mutations in vif-proficient HIV-1 provirus by individual APOBEC3 proteins in humanized mice

Reproduction of menstrual changes in transplanted human endometrial tissue in immunodeficient mice

Small intestine CD4+ cell reduction and enteropathy in simian/human immunodeficiency virus KS661-infected rhesus macaques in the presence of low viral load

Small ruminant lentiviral Vif proteins commonly utilize cyclophilin A, an evolutionarily and structurally conserved protein, to degrade ovine and caprine APOBEC3 proteins

Solution RNA structures of the HIV-1 dimerization initiation site in the kissing-loop and extended-duplex dimers

Species-specific differences in the ability of feline lentiviral Vif to degrade feline APOBEC3 proteins

Spirodiketopiperazine-based CCR5 inhibitor which preserves CC-chemokine/CCR5 interactions and exerts potent activity against R5 human immunodeficiency virus type 1 in vitro

T cell-based functional cDNA library screening identified SEC14-like 1a carboxy-terminal domain as a negative regulator of human immunodeficiency virus replication

The hematopoietic cell-specific Rho GTPase inhibitor ARHGDIB/D4GDI limits HIV type 1 replication

Tumor necrosis factor-related apoptosis-inducing ligand induces neuronal death in a murine model of HIV central nervous system infection

Various plus unique: Viral protein U as a plurifunctional protein for HIV-1 replication

Vif determines the requirement for CBF-β in APOBEC3 degradation

Vpu Augments the Initial Burst Phase of HIV-1 Propagation and Downregulates BST2 and CD4 in Humanized Mice ⬇️

Vpu and BST2: Still Not There Yet? ⬇️