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List of works by Marije Oosting

A Functional Genomics Approach to Understand Variation in Cytokine Production in Humans.

scientific article published on November 2016

A Genome-Wide Functional Genomics Approach Identifies Susceptibility Pathways to Fungal Bloodstream Infection in Humans

scientific article published on 01 July 2019

A role for TLR1, TLR2 and NOD2 in cytokine induction by Bacteroides fragilis.

scientific article

ADAMTS13 deficiency with elevated levels of ultra-large and active von Willebrand factor in P. falciparum and P. vivax malaria.

scientific article

Activation of innate host defense mechanisms by Borrelia

scientific article published on March 2010

An integrative genomics approach identifies novel pathways that influence candidaemia susceptibility

scientific article

Antibody neutralization of microbiota-derived circulating peptidoglycan dampens inflammation and ameliorates autoimmunity

scientific article published on 04 March 2019

Association of NF-κB polymorphisms with clinical outcome of non-medullary thyroid carcinoma

scientific article published on 20 April 2017

Autophagy controls BCG-induced trained immunity and the response to intravesical BCG therapy for bladder cancer

scientific article

Autophagy modulates Borrelia burgdorferi-induced production of interleukin-1β (IL-1β)

scientific article published on 5 February 2013

Autophagy modulates the Mycobacterium tuberculosis-induced cytokine response.

scientific article

Autophagy suppresses host adaptive immune responses toward Borrelia burgdorferi

scientific article published on 21 April 2016

BCG Vaccination Protects against Experimental Viral Infection in Humans through the Induction of Cytokines Associated with Trained Immunity

scientific article published in January 2018

BCG Vaccination in Humans Elicits Trained Immunity via the Hematopoietic Progenitor Compartment

scientific article published on 09 June 2020

Borrelia species induce inflammasome activation and IL-17 production through a caspase-1-dependent mechanism

scientific article published on 09 December 2010

Borrelia-induced cytokine production is mediated by spleen tyrosine kinase (Syk) but is Dectin-1 and Dectin-2 independent.

scientific article published on 18 August 2015

Causal relationships among the gut microbiome, short-chain fatty acids and metabolic diseases

scientific article published on 18 February 2019

Convergent evolution in European and Rroma populations reveals pressure exerted by plague on Toll-like receptors

scientific article published on 03 February 2014

Correction to: Rewiring of glucose metabolism defines trained immunity induced by oxidized low-density lipoprotein

scientific article published on 11 June 2020

Crohn's disease-associated ATG16L1 polymorphism modulates pro-inflammatory cytokine responses selectively upon activation of NOD2

scientific article published on 15 March 2011

Cytokine gene polymorphisms and the outcome of invasive candidiasis: a prospective cohort study

scientific article published on 5 December 2011

Differential Effects of Environmental and Genetic Factors on T and B Cell Immune Traits

scientific article

Effective collaboration between marginal metallophilic macrophages and CD8+ dendritic cells in the generation of cytotoxic T cells

scientific article

Engagement of fatty acids with Toll-like receptor 2 drives interleukin-1β production via the ASC/caspase 1 pathway in monosodium urate monohydrate crystal-induced gouty arthritis

scientific article

Erratum: Corrigendum: Inter-individual variability and genetic influences on cytokine responses to bacteria and fungi

article

Evolutionary and functional analysis of celiac risk loci reveals SH2B3 as a protective factor against bacterial infection

scientific article

Functional and Genomic Architecture of Borrelia burgdorferi-Induced Cytokine Responses in Humans.

scientific article published on November 2016

Functional genomics identifies type I interferon pathway as central for host defense against Candida albicans

scientific article published on January 2013

Gene polymorphisms in pattern recognition receptors and susceptibility to idiopathic recurrent vulvovaginal candidiasis

scientific article

Genetic Variation in TLR10, an Inhibitory Toll-Like Receptor, Influences Susceptibility to Complicated Skin and Skin Structure Infections

scientific article

Genetic deficiency of NOD2 confers resistance to invasive aspergillosis.

scientific article published on 6 July 2018

Genetic diversity of lactase persistence in East African populations.

scientific article published on 4 January 2016

Genetic variation in TLR10 is not associated with chronic Q fever, despite the inhibitory effect of TLR10 on Coxiella burnetii-induced cytokines in vitro.

scientific article published on 10 September 2015

Genetic variation in the dectin-1/CARD9 recognition pathway and susceptibility to candidemia

scientific article

Genetic variation in Interleukin-32 influence the immune response against New World Leishmania species and susceptibility to American Tegumentary Leishmaniasis

scientific article published on 05 February 2020

Gut Microbial Associations to Plasma Metabolites Linked to Cardiovascular Phenotypes and Risk

scientific article published on 11 April 2019

Gut microbial co-abundance networks show specificity in inflammatory bowel disease and obesity

scientific article published on 11 August 2020

High variability of TLR4 gene in different ethnic groups in Iran

scientific article published on 12 October 2011

Host and Environmental Factors Influencing Individual Human Cytokine Responses

scientific article published on November 2016

Human TLR10 is an anti-inflammatory pattern-recognition receptor

scientific article

Immunometabolic Pathways in BCG-Induced Trained Immunity

scientific article published on December 2016

Increased proteinase 3 and neutrophil elastase plasma concentrations are associated with non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes

scientific article published on 02 May 2019

Innate Immune Recognition of Mycobacterium tuberculosis

scientific article published on 07 April 2011

Innate immunity networks during infection with Borrelia burgdorferi

scientific article

Integrated Genomics of Crohn's Disease Risk Variant Identifies a Role for CLEC12A in Antibacterial Autophagy

scientific article published on 18 June 2015

Integration of multi-omics data and deep phenotyping enables prediction of cytokine responses

scientific article published on 21 May 2018

Inter-individual variability and genetic influences on cytokine responses to bacteria and fungi

scientific article published on 4 July 2016

Linking the Human Gut Microbiome to Inflammatory Cytokine Production Capacity

scientific article

Linking the Human Gut Microbiome to Inflammatory Cytokine Production Capacity

scientific article published on 01 December 2016

Murine Borrelia arthritis is highly dependent on ASC and caspase-1, but independent of NLRP3.

scientific article published on 13 November 2012

Platelet Integrin αIIbβ3 Activation is Associated with 25-Hydroxyvitamin D Concentrations in Healthy Adults

scientific article published on 05 May 2020

Polymorphisms in autophagy genes and susceptibility to tuberculosis

scientific article

Predicting bacterial infection outcomes using single cell RNA-sequencing analysis of human immune cells

scientific article published on 22 July 2019

Protective host defense against disseminated candidiasis is impaired in mice expressing human interleukin-37.

scientific article

Recognition of Borrelia burgdorferi by NOD2 is central for the induction of an inflammatory reaction

scientific article

Recognition of Coxiella burnetii by toll-like receptors and nucleotide-binding oligomerization domain-like receptors

scientific article published on 22 September 2014

Respiratory syncytial virus infection augments NOD2 signaling in an IFN‐β‐dependent manner in human primary cells

scientific article published on August 20, 2012

Rewiring of glucose metabolism defines trained immunity induced by oxidized low-density lipoprotein

scientific article published on 30 April 2020

Role of Dectin-2 for host defense against systemic infection with Candida glabrata.

scientific article published on 16 December 2013

Role of Glutamine Metabolism in Host Defense Against Mycobacterium tuberculosis Infection

scientific article published on 01 April 2019

Role of autophagy genetic variants for the risk of Candida infections.

scientific article

Role of glutathione metabolism in host defense against Borrelia burgdorferi infection

scientific article published on 14 February 2018

Role of interleukin-23 (IL-23) receptor signaling for IL-17 responses in human Lyme disease

scientific article published on 6 September 2011

Safety and COVID-19 Symptoms in Individuals Recently Vaccinated with BCG: a Retrospective Cohort Study

scientific article published on 05 August 2020

Soluble uric acid primes TLR-induced proinflammatory cytokine production by human primary cells via inhibition of IL-1Ra

scientific article published on 03 February 2015

TLR1, TLR2, and TLR6 gene polymorphisms are associated with increased susceptibility to complicated skin and skin structure infections.

scientific article published on 6 February 2014

TLR1/TLR2 Heterodimers Play an Important Role in the Recognition of Borrelia Spirochetes

scientific article published on October 5, 2011

The Itaconate Pathway Is a Central Regulatory Node Linking Innate Immune Tolerance and Trained Immunity

scientific article published on 04 October 2018

The NOD2 receptor is crucial for immune responses towards New World Leishmania species

scientific article published on 9 November 2017

The RIG-I-like helicase receptor MDA5 (IFIH1) is involved in the host defense against Candida infections

scientific article published on 13 January 2015

The Set7 Lysine Methyltransferase Regulates Plasticity in Oxidative Phosphorylation Necessary for Trained Immunity Induced by β-Glucan

scientific article published on 01 April 2020

The effect of host genetics on the gut microbiome

scientific article published on 03 October 2016

The role of Toll-like receptor 10 in modulation of trained immunity

scientific article published on 26 November 2019

The role of host immune cells and Borrelia burgdorferi antigens in the etiology of Lyme disease

scientific article

Tissue metabolic changes drive cytokine responses to Mycobacterium tuberculosis.

scientific article published on 3 April 2018

Toll-like receptor 1 polymorphisms increase susceptibility to candidemia.

scientific article published on February 2012

Understanding human immune function using the resources from the Human Functional Genomics Project

scientific article published on August 2016

Vitamin D3 down-regulates proinflammatory cytokine response to Mycobacterium tuberculosis through pattern recognition receptors while inducing protective cathelicidin production

scientific article published on May 17, 2011

Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming.

scientific article published in January 2018

β-Glucan-Induced Trained Immunity Protects against Leishmania braziliensis Infection: a Crucial Role for IL-32

scientific article published on 01 September 2019