List of works - Bruce William Stillman

The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA

scientific article (publication date: 16 June 1994)

Chromatin association of human origin recognition complex, cdc6, and minichromosome maintenance proteins during the cell cycle: assembly of prereplication complexes in late mitosis

scientific article

The DNA replication fork in eukaryotic cells.

scientific article

Nucleosome assembly by a complex of CAF-1 and acetylated histones H3/H4

scientific article

Differential effects by the p21 CDK inhibitor on PCNA-dependent DNA replication and repair.

scientific article published on October 1994

Anatomy of a DNA replication fork revealed by reconstitution of SV40 DNA replication in vitro

scientific article

A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication

scientific article

The knockout mouse project

scientific article

Cell cycle control of DNA replication.

scientific article

FASCIATA genes for chromatin assembly factor-1 in arabidopsis maintain the cellular organization of apical meristems

scientific article

p62(dok): a constitutively tyrosine-phosphorylated, GAP-associated protein in chronic myelogenous leukemia progenitor cells

scientific article

Formation of a Preinitiation Complex by S-phase Cyclin CDK-Dependent Loading of Cdc45p onto Chromatin

scientific article published on April 24, 1998

The p150 and p60 subunits of chromatin assembly factor I: a molecular link between newly synthesized histones and DNA replication

scientific article

Assembly of a complex containing Cdc45p, replication protein A, and Mcm2p at replication origins controlled by S-phase cyclin-dependent kinases and Cdc7p-Dbf4p kinase

scientific article

Deciphering protein kinase specificity through large-scale analysis of yeast phosphorylation site motifs

scientific article

Chromatin assembly coupled to DNA repair: a new role for chromatin assembly factor I.

scientific article published on September 1996

Heterochromatin Dynamics in Mouse Cells

scientific article (publication date: October 1999)

Biochemical characterization of DNA damage checkpoint complexes: clamp loader and clamp complexes with specificity for 5' recessed DNA

scientific article

Cdc7-Dbf4 phosphorylates MCM proteins via a docking site-mediated mechanism to promote S phase progression

scientific article

Human origin recognition complex large subunit is degraded by ubiquitin-mediated proteolysis after initiation of DNA replication

scientific article

Histone acetyltransferase HBO1 interacts with the ORC1 subunit of the human initiator protein

scientific journal article

Human Orc2 localizes to centrosomes, centromeres and heterochromatin during chromosome inheritance

scientific article

Chromatin assembly factor 1 is essential and couples chromatin assembly to DNA replication in vivo

scientific article published on September 30, 2003

Deregulation of cyclin E in human cells interferes with prereplication complex assembly

scientific article

PCNA connects DNA replication to epigenetic inheritance in yeast.

scientific article

Cdc6 is regulated by E2F and is essential for DNA replication in mammalian cells

scientific article published on March 31, 1998

Smart machines at the DNA replication fork.

scientific article published on September 1994

The Dbf4-Cdc7 kinase promotes S phase by alleviating an inhibitory activity in Mcm4

scientific article

A proposal for a coordinated effort for the determination of brainwide neuroanatomical connectivity in model organisms at a mesoscopic scale

scientific article (publication date: March 2009)

Perpetuating the double helix: molecular machines at eukaryotic DNA replication origins

scientific article published on December 2003

Principles and Concepts of DNA Replication in Bacteria, Archaea, and Eukarya

scientific article published on July 1, 2013

Orc6 involved in DNA replication, chromosome segregation, and cytokinesis.

scientific article

Break-induced replication requires all essential DNA replication factors except those specific for pre-RC assembly.

scientific article

Partial MCM4 deficiency in patients with growth retardation, adrenal insufficiency, and natural killer cell deficiency

scientific article published on 22 February 2012

Yph1p, an ORC-interacting protein: potential links between cell proliferation control, DNA replication, and ribosome biogenesis.

scientific article

ATPase-dependent cooperative binding of ORC and Cdc6 to origin DNA.

scientific article

Origin recognition and the chromosome cycle

scientific article

Orc1 controls centriole and centrosome copy number in human cells

scientific article published in February 2009

Cryo-EM structure of a helicase loading intermediate containing ORC-Cdc6-Cdt1-MCM2-7 bound to DNA.

scientific article published on 14 July 2013

A human protein related to yeast Cdc6p

scientific article

Sequential treatment of drug-resistant tumors with targeted minicells containing siRNA or a cytotoxic drug

scientific article

Constitutively high dNTP concentration inhibits cell cycle progression and the DNA damage checkpoint in yeast Saccharomyces cerevisiae.

scholarly article

Bacterially derived 400 nm particles for encapsulation and cancer cell targeting of chemotherapeutics

scientific article published on May 2007

Structure and function of the BAH-containing domain of Orc1p in epigenetic silencing

scientific article

Human origin recognition complex is essential for HP1 binding to chromatin and heterochromatin organization.

scientific article

The elongator complex interacts with PCNA and modulates transcriptional silencing and sensitivity to DNA damage agents.

scientific article

Replication-coupled chromatin assembly generates a neuronal bilateral asymmetry in C. elegans

scientific article published on 15 December 2011

ATP-dependent assembly of the human origin recognition complex

scientific article

The architecture of the DNA replication origin recognition complex in Saccharomyces cerevisiae

scholarly article

Simian virus 40 large T antigen binds to topoisomerase I.

scientific article published on August 1996

List of works by Bruce William Stillman

The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA

Chromatin association of human origin recognition complex, cdc6, and minichromosome maintenance proteins during the cell cycle: assembly of prereplication complexes in late mitosis

The DNA replication fork in eukaryotic cells.

Nucleosome assembly by a complex of CAF-1 and acetylated histones H3/H4

Differential effects by the p21 CDK inhibitor on PCNA-dependent DNA replication and repair.

Anatomy of a DNA replication fork revealed by reconstitution of SV40 DNA replication in vitro

A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication

The knockout mouse project

Cell cycle control of DNA replication.

FASCIATA genes for chromatin assembly factor-1 in arabidopsis maintain the cellular organization of apical meristems

p62(dok): a constitutively tyrosine-phosphorylated, GAP-associated protein in chronic myelogenous leukemia progenitor cells

Formation of a Preinitiation Complex by S-phase Cyclin CDK-Dependent Loading of Cdc45p onto Chromatin

The p150 and p60 subunits of chromatin assembly factor I: a molecular link between newly synthesized histones and DNA replication

Assembly of a complex containing Cdc45p, replication protein A, and Mcm2p at replication origins controlled by S-phase cyclin-dependent kinases and Cdc7p-Dbf4p kinase

Deciphering protein kinase specificity through large-scale analysis of yeast phosphorylation site motifs

Chromatin assembly coupled to DNA repair: a new role for chromatin assembly factor I.

Heterochromatin Dynamics in Mouse Cells

Biochemical characterization of DNA damage checkpoint complexes: clamp loader and clamp complexes with specificity for 5' recessed DNA

Cdc7-Dbf4 phosphorylates MCM proteins via a docking site-mediated mechanism to promote S phase progression

Human origin recognition complex large subunit is degraded by ubiquitin-mediated proteolysis after initiation of DNA replication

Histone acetyltransferase HBO1 interacts with the ORC1 subunit of the human initiator protein

Human Orc2 localizes to centrosomes, centromeres and heterochromatin during chromosome inheritance

Chromatin assembly factor 1 is essential and couples chromatin assembly to DNA replication in vivo

Deregulation of cyclin E in human cells interferes with prereplication complex assembly

PCNA connects DNA replication to epigenetic inheritance in yeast.

Cdc6 is regulated by E2F and is essential for DNA replication in mammalian cells

Smart machines at the DNA replication fork.

The Dbf4-Cdc7 kinase promotes S phase by alleviating an inhibitory activity in Mcm4

A proposal for a coordinated effort for the determination of brainwide neuroanatomical connectivity in model organisms at a mesoscopic scale

Perpetuating the double helix: molecular machines at eukaryotic DNA replication origins

Principles and Concepts of DNA Replication in Bacteria, Archaea, and Eukarya

Orc6 involved in DNA replication, chromosome segregation, and cytokinesis.

Break-induced replication requires all essential DNA replication factors except those specific for pre-RC assembly.

Partial MCM4 deficiency in patients with growth retardation, adrenal insufficiency, and natural killer cell deficiency

Yph1p, an ORC-interacting protein: potential links between cell proliferation control, DNA replication, and ribosome biogenesis.

ATPase-dependent cooperative binding of ORC and Cdc6 to origin DNA.

Origin recognition and the chromosome cycle

Orc1 controls centriole and centrosome copy number in human cells

Cryo-EM structure of a helicase loading intermediate containing ORC-Cdc6-Cdt1-MCM2-7 bound to DNA.

A human protein related to yeast Cdc6p

Sequential treatment of drug-resistant tumors with targeted minicells containing siRNA or a cytotoxic drug

Constitutively high dNTP concentration inhibits cell cycle progression and the DNA damage checkpoint in yeast Saccharomyces cerevisiae.

Bacterially derived 400 nm particles for encapsulation and cancer cell targeting of chemotherapeutics

Structure and function of the BAH-containing domain of Orc1p in epigenetic silencing

Human origin recognition complex is essential for HP1 binding to chromatin and heterochromatin organization.

The elongator complex interacts with PCNA and modulates transcriptional silencing and sensitivity to DNA damage agents.

Replication-coupled chromatin assembly generates a neuronal bilateral asymmetry in C. elegans

ATP-dependent assembly of the human origin recognition complex

The architecture of the DNA replication origin recognition complex in Saccharomyces cerevisiae

Simian virus 40 large T antigen binds to topoisomerase I.