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List of works by Bruce William Stillman

A common telomeric gene silencing assay is affected by nucleotide metabolism

scientific article published on April 2011

A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication

scientific article

A human protein related to yeast Cdc6p

scientific article

A proposal for a coordinated effort for the determination of brainwide neuroanatomical connectivity in model organisms at a mesoscopic scale

scientific article (publication date: March 2009)

ABF1-binding sites promote efficient global genome nucleotide excision repair

scientific article published on 6 November 2008

ATP-dependent assembly of the human origin recognition complex

scientific article

ATPase-dependent cooperative binding of ORC and Cdc6 to origin DNA.

scientific article

Acquired dependence of acute myeloid leukemia on the DEAD-box RNA helicase DDX5.

scientific article

An analysis of CAF-1-interacting proteins reveals dynamic and direct interactions with the KU complex and 14-3-3 proteins.

scientific article

Anatomy of a DNA replication fork revealed by reconstitution of SV40 DNA replication in vitro

scientific article

Assembly of a complex containing Cdc45p, replication protein A, and Mcm2p at replication origins controlled by S-phase cyclin-dependent kinases and Cdc7p-Dbf4p kinase

scientific article

Bacterially derived 400 nm particles for encapsulation and cancer cell targeting of chemotherapeutics

scientific article published on May 2007

Binding of cyclin-dependent kinases to ORC and Cdc6p regulates the chromosome replication cycle

scientific article

Biochemical characterization of DNA damage checkpoint complexes: clamp loader and clamp complexes with specificity for 5' recessed DNA

scientific article

Break-induced replication requires all essential DNA replication factors except those specific for pre-RC assembly. ⬇️

scientific article

Cdc6 is regulated by E2F and is essential for DNA replication in mammalian cells ⬇️

scientific article published on March 31, 1998

Cdc6-induced conformational changes in ORC bound to origin DNA revealed by cryo-electron microscopy

scientific article published in March 2012

Cdc7-Dbf4 phosphorylates MCM proteins via a docking site-mediated mechanism to promote S phase progression

scientific article

Cell cycle control of DNA replication.

scientific article

Chromatin assembly coupled to DNA repair: a new role for chromatin assembly factor I.

scientific article published on September 1996

Chromatin assembly factor 1 is essential and couples chromatin assembly to DNA replication in vivo ⬇️

scientific article published on September 30, 2003

Chromatin association of human origin recognition complex, cdc6, and minichromosome maintenance proteins during the cell cycle: assembly of prereplication complexes in late mitosis

scientific article

Constitutively high dNTP concentration inhibits cell cycle progression and the DNA damage checkpoint in yeast Saccharomyces cerevisiae.

scholarly article

Cryo-EM structure of Mcm2-7 double hexamer on DNA suggests a lagging-strand DNA extrusion model.

scientific article published on 25 October 2017

Cryo-EM structure of a helicase loading intermediate containing ORC-Cdc6-Cdt1-MCM2-7 bound to DNA.

scientific article published on 14 July 2013

DDX5 regulates DNA replication and is required for cell proliferation in a subset of breast cancer cells

scientific article

DNA polymerases at the replication fork in eukaryotes

scientific article published on May 2008

DNA replication. Replicator renaissance.

scientific article published in December 1993

Deciphering protein kinase specificity through large-scale analysis of yeast phosphorylation site motifs

scientific article

Deoxynucleoside triphosphate (dNTP) synthesis and destruction regulate the replication of both cell and virus genomes.

scientific article published on 14 August 2013

Deregulation of cyclin E in human cells interferes with prereplication complex assembly

scientific article

Differential effects by the p21 CDK inhibitor on PCNA-dependent DNA replication and repair.

scientific article published on October 1994

Domain within the helicase subunit Mcm4 integrates multiple kinase signals to control DNA replication initiation and fork progression

scientific article

Dynamics of pre-replication complex proteins during the cell division cycle

scientific article

Evolution of DNA replication origin specification and gene silencing mechanisms

scientific article published on 14 October 2020

FASCIATA genes for chromatin assembly factor-1 in arabidopsis maintain the cellular organization of apical meristems

scientific article

Formation of a Preinitiation Complex by S-phase Cyclin CDK-Dependent Loading of Cdc45p onto Chromatin ⬇️

scientific article published on April 24, 1998

Functions of sensor 1 and sensor 2 regions of Saccharomyces cerevisiae Cdc6p in vivo and in vitro

scientific article published on 4 February 2002

Heterochromatin Dynamics in Mouse Cells

scientific article (publication date: October 1999)

Histone acetyltransferase HBO1 interacts with the ORC1 subunit of the human initiator protein

scientific journal article

Human Orc2 localizes to centrosomes, centromeres and heterochromatin during chromosome inheritance

scientific article

Human Orc2 localizes to centrosomes, centromeres and heterochromatin during chromosome inheritance

Human origin recognition complex is essential for HP1 binding to chromatin and heterochromatin organization.

scientific article

Human origin recognition complex large subunit is degraded by ubiquitin-mediated proteolysis after initiation of DNA replication

scientific article

Human-Saccharomyces cerevisiae proliferating cell nuclear antigen hybrids: oligomeric structure and functional characterization using in vitro DNA replication

scientific article published on 27 November 2000

Identification of eukaryotic DNA replication proteins using simian virus 40 in vitro replication system

scientific article published in January 1995

Immunoblotting histones from yeast whole-cell protein extracts

scientific article

Interaction of a nuclear factor with the polyomavirus enhancer region.

scientific article

Joseph F. Sambrook (1939-2019)

scientific article published on 01 October 2019

Meier-Gorlin syndrome mutations disrupt an Orc1 CDK inhibitory domain and cause centrosome reduplication

scientific article

Nucleosome assembly by a complex of CAF-1 and acetylated histones H3/H4

scientific article

Opening of the clamp: an intimate view of an ATP-driven biological machine.

scientific article

Opposing roles for DNA replication initiator proteins ORC1 and CDC6 in control of Cyclin E gene transcription

scientific article published on 26 July 2016

Orc1 controls centriole and centrosome copy number in human cells

scientific article published in February 2009

Orc6 involved in DNA replication, chromosome segregation, and cytokinesis.

scientific article

Origin recognition and the chromosome cycle

scientific article

PCNA connects DNA replication to epigenetic inheritance in yeast.

scientific article

Partial MCM4 deficiency in patients with growth retardation, adrenal insufficiency, and natural killer cell deficiency

scientific article published on 22 February 2012

Perpetuating the double helix: molecular machines at eukaryotic DNA replication origins

scientific article published on December 2003

Phosphorylation of H4 Ser 47 promotes HIRA-mediated nucleosome assembly.

scientific article

Principles and concepts of DNA replication in bacteria, archaea, and eukarya

scientific article published on July 2013

Reconstitution of recombinant human replication factor C (RFC) and identification of an RFC subcomplex possessing DNA-dependent ATPase activity

scientific article

Replication-coupled chromatin assembly generates a neuronal bilateral asymmetry in C. elegans

scientific article published on 15 December 2011

Reversible suppression of an essential gene in adult mice using transgenic RNA interference

scientific journal article

Sequential treatment of drug-resistant tumors with targeted minicells containing siRNA or a cytotoxic drug

scientific article

Simian virus 40 large T antigen binds to topoisomerase I.

scientific article published on August 1996

Smart machines at the DNA replication fork.

scientific article published on September 1994

Structural basis for origin recognition complex 1 protein-silence information regulator 1 protein interaction in epigenetic silencing

scientific article

Structural basis of Mcm2-7 replicative helicase loading by ORC-Cdc6 and Cdt1.

scientific article published on 13 February 2017

Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6

scientific article published on 15 July 2020

Structure and function of the BAH-containing domain of Orc1p in epigenetic silencing

scientific article

Structure of the active form of human origin recognition complex and its ATPase motor module

scientific article published on 23 January 2017

The DNA replication fork in eukaryotic cells.

scientific article

The Dbf4-Cdc7 kinase promotes S phase by alleviating an inhibitory activity in Mcm4

scientific article

The N-terminal domains of histones H3 and H4 are not necessary for chromatin assembly factor-1- mediated nucleosome assembly onto replicated DNA in vitro.

scientific article published in July 2000

The architecture of the DNA replication origin recognition complex in Saccharomyces cerevisiae

scholarly article

The dNTP triphosphohydrolase activity of SAMHD1 persists during S-phase when the enzyme is phosphorylated at T592

scientific article published on 24 July 2018

The elongator complex interacts with PCNA and modulates transcriptional silencing and sensitivity to DNA damage agents.

scientific article

The initiation of chromosomal DNA replication in eukaryotes

scientific article published on December 1990

The knockout mouse project

scientific article

The origin recognition complex: a biochemical and structural view

scientific article published on January 2012

The p150 and p60 subunits of chromatin assembly factor I: a molecular link between newly synthesized histones and DNA replication

scientific article

The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA

scientific article (publication date: 16 June 1994)

Yeast autonomously replicating sequence binding factor is involved in nucleotide excision repair.

scientific article

Yph1p, an ORC-interacting protein: potential links between cell proliferation control, DNA replication, and ribosome biogenesis.

scientific article

p62(dok): a constitutively tyrosine-phosphorylated, GAP-associated protein in chronic myelogenous leukemia progenitor cells

scientific article

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