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List of works by Faramarz Ismail-Beigi

"Register-shift" insulin analogs uncover constraints of proteotoxicity in protein evolution

scientific article published on 31 January 2020

6-Fluoro-6-deoxy-D-glucose as a tracer of glucose transport

scientific article published on 3 April 2007

A View Beyond HbA1c: Role of Continuous Glucose Monitoring.

scientific article published on 29 April 2019

A controlled trial of CPAP therapy on metabolic control in individuals with impaired glucose tolerance and sleep apnea

scientific article published in May 2012

A new Michaelis–Menten‐based kinetic model for transport and phosphorylation of glucose and its analogs in skeletal muscle ⬇️

scientific article published on August 1, 2011

Action to Control Cardiovascular Risk in Diabetes (ACCORD) Trial—Clinical Implications ⬇️

scientific article published on October 25, 2010

Adverse Effects of Glycemia-Lowering Medications in Type 2 Diabetes

scientific article published on 20 November 2019

American Association of Clinical Endocrinologists Medical Guidelines for Clinical Practice for Developing a Diabetes Mellitus Comprehensive Care Plan ⬇️

scientific article published on 01 March 2011

American Association of Clinical Endocrinologists Medical Guidelines for Clinical Practice for Developing a Diabetes Mellitus Comprehensive Care Plan: Executive Summary ⬇️

scientific article published on 01 March 2011

American Association of Clinical Endocrinologists and American Diabetes Association consensus statement on inpatient glycemic control

scientific article published on 08 May 2009

American Association of Clinical Endocrinologists and American Diabetes Association consensus statement on inpatient glycemic control.

scientific article

An Achilles' heel in an amyloidogenic protein and its repair: insulin fibrillation and therapeutic design

scientific article

An ultra-stable single-chain insulin analog resists thermal inactivation and exhibits biological signaling duration equivalent to the native protein

scientific article published on 7 November 2017

Analysis of metabolism of 6FDG: a PET glucose transport tracer ⬇️

scientific article published on March 3, 2011

Antidepressant response associated with pioglitazone: support for an overlapping pathophysiology between major depression and metabolic syndrome

scientific article published on May 2009

Aromatic anchor at an invariant hormone-receptor interface: function of insulin residue B24 with application to protein design.

scientific article

Association of Fenofibrate Therapy With Long-term Cardiovascular Risk in Statin-Treated Patients With Type 2 Diabetes

scientific article published on 28 December 2016

Association of Urinary Biomarkers of Inflammation, Injury, and Fibrosis with Renal Function Decline: The ACCORD Trial.

scientific article published on 17 May 2016

Biophysical optimization of a therapeutic protein by nonstandard mutagenesis: studies of an iodo-insulin derivative

scientific article

Challenging Issues in the Management of Cardiovascular Risk Factors in Diabetes During the COVID-19 Pandemic: A Review of Current Literature

scientific article published on 06 July 2020

Clinical practice. Glycemic management of type 2 diabetes mellitus

scientific article published on April 2012

Combined intensive blood pressure and glycemic control does not produce an additive benefit on microvascular outcomes in type 2 diabetic patients.

scientific article

Comparisons of different insulin infusion protocols: a review of recent literature

scientific article published on March 2010

Connecting Rodent and Human Pharmacokinetic Models for the Design and Translation of Glucose-Responsive Insulin

scientific article published on 09 March 2020

Control of Glut1 promoter activity under basal conditions and in response to hyperosmolarity: role of Sp1.

scientific article published on 14 September 2005

Control of Na+-K+-ATPase beta 1-subunit expression: role of 3'-untranslated region

scientific article published on 01 March 2004

Critical role of 5'-AMP-activated protein kinase in the stimulation of glucose transport in response to inhibition of oxidative phosphorylation

scientific article published on 30 August 2006

DEXAMETHASONE STRESS TEST: A PILOT CLINICAL STUDY FOR IDENTIFICATION OF INDIVIDUALS HIGHLY PRONE TO DEVELOP TYPE 2 DIABETES

scientific article published on 07 August 2018

Depressive symptoms and diabetes

scientific article published on November 2008

Design of an Insulin Analog with Enhanced Receptor Binding Selectivity: RATIONALE, STRUCTURE, AND THERAPEUTIC IMPLICATIONS

scientific article

Determinants of glycemic control: Phase 2 analysis from nationwide diabetes report of National Program for Prevention and Control of Diabetes (NPPCD-2018)

scientific article published on 08 August 2019

Determinants of successful glycemic control among participants in the BARI 2D trial: a post-hoc analysis

scientific article

Determinants of weight gain in the action to control cardiovascular risk in diabetes trial

scientific article published on 14 February 2013

Dexamethasone-induced insulin resistance: kinetic modeling using novel PET radiopharmaceutical 6-deoxy-6-[(18)F]fluoro-D-glucose

scientific article

Diabetes in Iran: Prospective Analysis from First Nationwide Diabetes Report of National Program for Prevention and Control of Diabetes (NPPCD-2016).

scientific article published on 18 October 2017

Diabetic retinopathy, its progression, and incident cardiovascular events in the ACCORD trial

scientific article

Differential accumulation of Glut1 in the non-DRM domain of the plasma membrane in response to the inhibition of oxidative phosphorylation

scientific article published in November 2004

Distribution of Glut1 in detergent-resistant membranes (DRMs) and non-DRM domains: effect of treatment with azide

scientific article published on 9 April 2003

Disturbances in Insulin-Glucose Metabolism in Patients With Advanced Renal Disease With and Without Diabetes

scientific article published on 01 November 2019

Durable change in glycaemic control following intensive management of type 2 diabetes in the ACCORD clinical trial

scientific article

Effect of Dexamethasone on Glucose Homeostasis In Normal and Prediabetic Subjects With A First-Degree Relative With Type 2 Diabetes Mellitus ⬇️

scientific article published on November 1, 2012

Effect of dexamethasone on insulin secretion: examination of underlying mechanisms

scientific article published in September 2010

Effect of dexamethasone on oral glucose tolerance in healthy adults

scientific article published in September 2010

Effect of hypoglycemia on brain structure in people with type 2 diabetes: epidemiological analysis of the ACCORD-MIND MRI trial

scientific article

Effect of intensive compared with standard glycemia treatment strategies on mortality by baseline subgroup characteristics: the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial

scientific article

Effect of intensive treatment of hyperglycaemia on microvascular outcomes in type 2 diabetes: an analysis of the ACCORD randomised trial

scientific article

Effect of thiazolidinediones and insulin on cognitive outcomes in ACCORD-MIND.

scientific article published on 13 May 2013

Effect of thyroid hormone on the distribution and activity of Na, K-ATPase in ventricular myocardium

scientific article published on 22 April 2008

Effect of thyroid hormone on uncoupling protein-3 mRNA expression in rat heart and skeletal muscle

scientific article published in March 2004

Effects of combination lipid therapy in type 2 diabetes mellitus

scientific article

Effects of intensive blood-pressure control in type 2 diabetes mellitus

scientific article

Effects of intensive glycaemic control on ischaemic heart disease: analysis of data from the randomised, controlled ACCORD trial

scientific article

Efficacy of high-fiber diets in the management of type 2 diabetes mellitus

scientific article published on January 2011

Endothelin-1 Increases Collagen Accumulation in Renal Mesangial Cells by Stimulating a Chemokine and Cytokine Autocrine Signaling Loop ⬇️

scientific article published on December 17, 2010

Exposure to azide markedly decreases the abundance of mRNAs encoding cholesterol synthetic enzymes and inhibits cholesterol synthesis

scientific article published on March 2007

Factors Leading to High Morbidity and Mortality of COVID-19 in Patients with Type 2 Diabetes

scientific article published on 16 July 2020

Glucocorticoid-Induced Fatty Liver Disease

scientific article published on 16 April 2020

Glucose uptake and lactate production in cells exposed to CoCl(2) and in cells overexpressing the Glut-1 glucose transporter

scientific article published on March 2002

Glycemia management and cardiovascular risk in type 2 diabetes: an evolving perspective

scientific article published on July 2008

Glycemia treatment strategies in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial

scientific article published on 19 April 2007

Glycemia-lowering effect of cobalt chloride in the diabetic rat: role of decreased gluconeogenesis ⬇️

scientific article published on June 1, 1998

Human radiation dosimetry of 6-[18F]FDG predicted from preclinical studies

scientific article published on March 2014

Hyperglycemia-induced stimulation of glucose transport in skeletal muscle measured by PET-[18F]6FDG and [18F]2FDG.

scientific article

Hypoglycemia: minimizing its impact in type 2 diabetes

scientific article published on May 2013

Impact of quality mentorship on achievements of Shiraz Medical School in the 1970s and the role of Professors Khosrow Nasr and Asghar Rastegar

scientific article published in April 2013

Impaired fasting glucose and major adverse cardiovascular events by hypertension and dyslipidemia status: the Golestan cohort study

scientific article published on 05 March 2020

Individualizing Glycemic Targets in Type 2 Diabetes Mellitus: Implications of Recent Clinical Trials ⬇️

scientific article published on April 19, 2011

Insulin Dose and Cardiovascular Mortality in the ACCORD Trial

scientific article published on 13 October 2015

Insulin Fibrillation and Protein Design: Topological Resistance of Single-Chain Analogs to Thermal Degradation with Application to a Pump Reservoir ⬇️

scientific article published on March 1, 2012

Intermittent Fasting and "Metabolic Switch": Effects on Metabolic Syndrome, Pre-diabetes and Type 2 Diabetes Mellitus

scientific article published on 06 May 2020

Long-Term Effects of Intensive Glucose Lowering on Cardiovascular Outcomes ⬇️

scientific article published on March 3, 2011

Long-Term Effects of Intensive Glycemic and Blood Pressure Control and Fenofibrate Use on Kidney Outcomes

scientific article published on 25 October 2018

Metabolic programming: fetal origins of obesity and metabolic syndrome in the adult

scientific article

Near-Normalization of Glucose and Microvascular Diabetes Complications: Data from ACCORD and ADVANCE.

scientific article

PPAR-γ agonism as a modulator of mood: proof-of-concept for pioglitazone in bipolar depression

scientific article

PS2-27: Near-Normalization of Glucose and Microvascular Diabetes Complications: Data from ACCORD and ADVANCE.

scientific article

Paradoxical reduction in HDL-C with fenofibrate and thiazolidinedione therapy in type 2 diabetes: the ACCORD Lipid Trial.

scientific article published on 02 December 2013

Pathogenesis and glycemic management of type 2 diabetes mellitus: a physiological approach

scientific article published on April 1, 2012

Pioglitazone Prevents Diabetes in Patients With Insulin Resistance and Cerebrovascular Disease

scientific article published on 27 July 2016

Poor cognitive function and risk of severe hypoglycemia in type 2 diabetes: post hoc epidemiologic analysis of the ACCORD trial

scientific article published on 28 February 2012

Predictive and explanatory factors of cardiovascular disease in people with adequately controlled type 2 diabetes

scientific article published on 27 April 2017

Preservation of Beta-Cell Function in Type 2 Diabetes ⬇️

scientific article published on November 1, 2010

Prolonged Exposure to Insulin Inactivates Akt and Erk1/2 and Increases Pancreatic Islet and INS1E β-Cell Apoptosis.

scientific article published in November 2018

Protective hinge in insulin opens to enable its receptor engagement

scientific article

Reassessment of an Innovative Insulin Analogue Excludes Protracted Action yet Highlights the Distinction between External and Internal Diselenide Bridges

scientific article published on 18 March 2020

Recommendations for management of diabetes during Ramadan

scientific article

Reduction of Insulin Resistance and Plasma Glucose Level by Salsalate Treatment in Persons With Prediabetes ⬇️

scientific article published on November 1, 2012

Relationships between cerebral structure and cognitive function in African Americans with type 2 diabetes

scientific article published on 29 May 2018

Response to Comment on Inzucchi et al. Pioglitazone Prevents Diabetes in Patients With Insulin Resistance and Cerebrovascular Disease. Diabetes Care 2016;39:1684-1692.

scientific article

Risk of insulin accumulation (stacking) with use of novel ultralong-acting insulin formulations

scientific article published in September 2014

Role of 5'-AMP-activated protein kinase in stimulation of glucose transport in response to inhibition of oxidative phosphorylation

scientific article published on 14 September 2005

Role of intensive glucose control in development of renal end points in type 2 diabetes mellitus: systematic review and meta-analysis intensive glucose control in type 2 diabetes

scientific article

SGLT-2 inhibitors as promising therapeutics for non-alcoholic fatty liver disease: pathophysiology, clinical outcomes, and future directions

scientific article published on 03 July 2019

Salsalate improves glycemic control in patients with newly diagnosed type 2 diabetes.

scientific article

Severe hypoglycemia symptoms, antecedent behaviors, immediate consequences and association with glycemia medication usage: Secondary analysis of the ACCORD clinical trial data ⬇️

scientific article published on May 30, 2012

Shifting Paradigms in the Medical Management of Type 2 Diabetes: Reflections on Recent Cardiovascular Outcome Trials

scientific article published on 26 May 2017

Smoking and Diabetes Control in Adults With Type 1 and Type 2 Diabetes: A Nationwide Study From the 2018 National Program for Prevention and Control of Diabetes of Iran

scientific article published on 12 July 2019

Solution structure of an ultra-stable single-chain insulin analog connects protein dynamics to a novel mechanism of receptor binding

scientific article published on 7 November 2017

Stimulation of Glucose Transport by Hypoxia: Signals and Mechanisms

scientific article published on 01 June 1999

Stimulation of glucose transport in response to activation of distinct AMPK signaling pathways

scientific article published on 13 August 2008

Structure-based stabilization of insulin as a therapeutic protein assembly via enhanced aromatic-aromatic interactions

scientific article published on 07 June 2018

Supramolecular Protein Engineering: DESIGN OF ZINC-STAPLED INSULIN HEXAMERS AS A LONG ACTING DEPOT

scientific article

The Relationship Between the Score on a Simple Measure of Cognitive Function and Incident CVD in People With Diabetes: A Post Hoc Epidemiological Analysis From the ACCORD-MIND Study

scientific article published on June 2017

The association between symptomatic, severe hypoglycaemia and mortality in type 2 diabetes: retrospective epidemiological analysis of the ACCORD study

scientific article

The degree of retinopathy is equally predictive for renal and macrovascular outcomes in the ACCORD Trial

scientific article

The effects of medical management on the progression of diabetic retinopathy in persons with type 2 diabetes: the Action to Control Cardiovascular Risk in Diabetes (ACCORD) Eye Study

scientific article

The renal transcriptome of db/db mice identifies putative urinary biomarker proteins in patients with type 2 diabetes: a pilot study ⬇️

scientific article published on December 28, 2011

Thyroid hormone regulation of cardiac bioenergetics: role of intracellular creatine

scientific article published in December 2002

Triglyceride High-Density Lipoprotein Ratios Predict Glycemia-Lowering in Response to Insulin Sensitizing Drugs in Type 2 Diabetes: A Post Hoc Analysis of the BARI 2D.

scientific article

Uptake of 18F-labeled 6-fluoro-6-deoxy-D-glucose by skeletal muscle is responsive to insulin stimulation

scientific article published on 14 May 2009

Use of insulin sensitizers for the treatment of major depressive disorder: A pilot study of pioglitazone for major depression accompanied by abdominal obesity ⬇️

scientific article published on July 22, 2011

Using 2H2O to study the influence of feeding on protein synthesis: effect of isotope equilibration in vivo vs. in cell culture.

scientific article published on 25 January 2005

α-Helical element at the hormone-binding surface of the insulin receptor functions as a signaling element to activate its tyrosine kinase

scientific article

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