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List of works by Kazuyoshi Saito

5-year remission rate after the discontinuation of adalimumab in patients with rheumatoid arthritis: Long-term follow-up results of the HONOR study

scientific article published on 15 January 2020

A case of Paragonimiasis westermanii complicated with migrating subcutaneous induration and multiple involvements in the liver

scientific article published on August 2002

A case of blue rubber bleb nevus syndrome treated by etidronate

scientific article published on 26 February 2007

A case of catastrophic antiphospholipid antibody syndrome complicated with systemic lupus erythematosus, double positive for anti-cardiolipin/β2 glycoprotein I and anti-phosphatidylserine/prothrombin autoantibodies

scientific article published on November 29, 2011

A case of life-threatening refractory polychondritis successfully treated with combined intensive immunosuppressive therapy with methotrexate

scientific article published on 20 April 2007

A genome-wide association study identified AFF1 as a susceptibility locus for systemic lupus eyrthematosus in Japanese

scientific journal article

A merged presentation of clinical and radiographic data using probability plots in a clinical trial, the JESMR study

scientific article

A multi-biomarker disease activity score tracks clinical response consistently in patients with rheumatoid arthritis treated with different anti-tumor necrosis factor therapies: A retrospective observational study

scientific article published on 8 October 2014

A multicenter phase I/II trial of rituximab for refractory systemic lupus erythematosus

article

Abatacept inhibits radiographic progression in patients with rheumatoid arthritis: a retrospective analysis of 6 months of abatacept treatment in routine clinical practice. The ALTAIR study

scientific article published on 01 January 2014

Abatacept therapy reduces CD28+CXCR5+ follicular helper-like T cells in patients with rheumatoid arthritis

scientific article published on 27 April 2017

Abnormal intracellular distribution of NFAT1 in T lymphocytes from patients with systemic lupus erythematosus and characteristic clinical features

scientific article published on 28 February 2006

Activation of Syk in peripheral blood B cells in patients with rheumatoid arthritis: a potential target for abatacept therapy.

scientific article published in January 2015

Activation signal transduction by beta1 integrin in T cells from patients with systemic lupus erythematosus

scientific article published on 01 May 2007

Active arthritis due to cryoglobulinemia based on HCV infection in a patient with RA improvement of arthritis with IFN-alpha

scientific article published in February 2004

Alendronate protects premenopausal women from bone loss and fracture associated with high-dose glucocorticoid therapy

scientific article published in November 2008

Analysis of bone metabolism during early stage and clinical benefits of early intervention with alendronate in patients with systemic rheumatic diseases treated with high-dose glucocorticoid: Early DIagnosis and Treatment of OsteopoRosis in Japan (E

scientific article published on 26 August 2015

Association of the multi-biomarker disease activity score with joint destruction in patients with rheumatoid arthritis receiving tumor necrosis factor-alpha inhibitor treatment in clinical practice

scientific article published on 30 March 2016

B cell or T cell-dominant recurrence after rituximab therapy in patients with SLE

scientific article published on May 14, 2012

Beta1 integrin/focal adhesion kinase-mediated signaling induces intercellular adhesion molecule 1 and receptor activator of nuclear factor kappaB ligand on osteoblasts and osteoclast maturation

scientific article published on 3 September 2003

Blood autoantibody and cytokine profiles predict response to anti-tumor necrosis factor therapy in rheumatoid arthritis

scientific article published on 21 May 2009

C5a promotes migration, proliferation, and vessel formation in endothelial cells

scientific article published on 9 March 2010

Case of pulmonary infection with Mycobacterium chelonae in healthy breast-feeding woman

scientific article published in October 2007

Case of severe liver damage after the induction of tocilizumab therapy for rheumatoid vasculitis

scientific article published on March 21, 2011

Clinical images: Takayasu arteritis diagnosed by positron emission tomography

scientific article published on 01 July 2007

Clinical implication of cyclosporin for systemic autoimmune diseases: relevance to multidrug resistance

scientific article published in February 2002

Clinical relevance of the expression of P-glycoprotein on peripheral blood lymphocytes to steroid resistance in patients with systemic lupus erythematosus

scientific article published in June 2005

Clinical, radiographic and functional effectiveness of tocilizumab for rheumatoid arthritis patients--REACTION 52-week study

scientific article

Clinical, radiographic and functional efficacy of abatacept in routine care for rheumatoid arthritis patients: Abatacept Leading Trial for RA on Imaging Remission (ALTAIR) study

scientific article published on 31 August 2016

Clinically relevant radiographic progression in joint destruction in RA patients with abnormal MMP-3 or high levels of CRP despite 1-year treatment with infliximab.

scientific article published on 26 April 2016

Comparison of efficacy of TNF inhibitors and abatacept in patients with rheumatoid arthritis; Adjusted with propensity score matching

scientific article published on 31 March 2018

Comparison of the efficacies of abatacept and tocilizumab in patients with rheumatoid arthritis by propensity score matching

scientific article published on 5 August 2015

Complete resolution of dermatomyositis with refractory cutaneous vasculitis by intravenous cyclophosphamide pulse therapy

scientific article

Continuation of Methotrexate Resulted in Better Clinical and Radiographic Outcomes Than Discontinuation upon Starting Etanercept in Patients with Rheumatoid Arthritis: 52-week Results from the JESMR Study

scientific article published on 15 May 2011

Correlation of T follicular helper cells and plasmablasts with the development of organ involvement in patients with IgG4-related disease

scientific article published on 14 December 2017

Dermal mast cell density in fingers reflects severity of skin sclerosis in systemic sclerosis

scientific article published on December 28, 2012

Diagnosis of early-stage rheumatoid arthritis: usefulness of unenhanced and gadolinium-enhanced MR images at 3 T

scientific article published on August 20, 2012

Differential effects of biological DMARDs on peripheral immune cell phenotypes in patients with rheumatoid arthritis

scientific article

Discontinuation of adalimumab after achieving remission in patients with established rheumatoid arthritis: 1-year outcome of the HONOR study

scientific article

Discontinuation of adalimumab after attaining disease activity score 28-erythrocyte sedimentation rate remission in patients with rheumatoid arthritis (HONOR study): an observational study

scientific article published on 25 September 2013

Discontinuation of etanercept after achievement of sustained remission in patients with rheumatoid arthritis who initially had moderate disease activity-results from the ENCOURAGE study, a prospective, international, multicenter randomized study

scientific article published on 23 December 2015

Discontinuation of infliximab in rheumatoid arthritis patients in clinical remission

scientific article published on 6 June 2008

Dopamine D2-like receptor signaling suppresses human osteoclastogenesis

scientific article published on April 28, 2013

Dopamine Induces IL-6–Dependent IL-17 Production via D1-Like Receptor on CD4 Naive T Cells and D1-Like Receptor Antagonist SCH-23390 Inhibits Cartilage Destruction in a Human Rheumatoid Arthritis/SCID Mouse Chimera Model

scientific article published on February 9, 2011

Dopamine as an immune-modulator between dendritic cells and T cells and the role of dopamine in the pathogenesis of rheumatoid arthritis

scientific article published in February 2009

Drug retention rates and relevant risk factors for drug discontinuation due to adverse events in rheumatoid arthritis patients receiving anticytokine therapy with different target molecules

scientific article published on 13 April 2012

Effect of interleukin-6 receptor inhibitor, tocilizumab, in preventing joint destruction in patients with rheumatoid arthritis showing inadequate response to TNF inhibitors.

scientific article published on 5 November 2013

Effectiveness and safety of adalimumab in Japanese patients with rheumatoid arthritis: retrospective analyses of data collected during the first year of adalimumab treatment in routine clinical practice (HARMONY study).

scientific article

Effectiveness of abatacept for patients with Sjögren's syndrome associated with rheumatoid arthritis. An open label, multicenter, one-year, prospective study: ROSE (Rheumatoid Arthritis with Orencia Trial toward Sjögren's syndrome Endocrinopathy) tr

scientific article published on 26 July 2016

Effects of anti-TNF-alpha antibody infliximab in refractory entero-Behcet's disease

scientific article published on 22 May 2009

Efficacy and safety of abatacept for patients with Sjögren's syndrome associated with rheumatoid arthritis: rheumatoid arthritis with orencia trial toward Sjögren's syndrome Endocrinopathy (ROSE) trial-an open-label, one-year, prospective study-Inte

scientific article

Efficacy and safety of mizoribine for the treatment of Sjögren's syndrome: a multicenter open-label clinical trial

scientific article

Efficacy and safety of reducing duration of infliximab infusion.

scientific article

Efficacy and tolerability of tocilizumab in rheumatoid arthritis patients seen in daily clinical practice in Japan: results from a retrospective study (REACTION study).

scientific article

Efficacy of Intravenous Cyclophosphamide Pulse Therapy for P-Glycoprotein-expressing B Cell-associated Active True Renal Lupus Vasculitis in Lupus Nephritis

scientific article published on 15 June 2017

Efficacy of combination therapy of anti-TNF-α antibody infliximab and methotrexate in refractory entero-Behçet’s disease

scientific article published on November 5, 2010

Efficacy of mizoribine treatment in patients with Sjögren's syndrome: an open pilot trial

scientific article published in December 2003

Efficacy of rituximab (anti-CD20) for refractory systemic lupus erythematosus involving the central nervous system

scientific article published on 15 November 2006

Engagement of CD44 up-regulates Fas Ligand expression on T cells leading to activation-induced cell death

article by Kazuhisa Nakano et al published 21 November 2006 in Apoptosis

Enhanced effect of high-dose leukocytapheresis using a large filter in rheumatoid arthritis

scientific article published on 20 December 2007

Etanercept (ETN) with methotrexate (MTX) is better than ETN monotherapy in patients with active rheumatoid arthritis despite MTX therapy: a randomized trial

scholarly article by Hideto Kameda et al published 24 June 2010 in Modern Rheumatology

Etanercept overcomes P-glycoprotein-induced drug resistance in lymphocytes of patients with intractable rheumatoid arthritis

scientific article published on 14 November 2009

Etidronate prevents high dose glucocorticoid induced bone loss in premenopausal individuals with systemic autoimmune diseases

scientific article

Evaluation of the alternative classification criteria of systemic lupus erythematosus established by Systemic Lupus International Collaborating Clinics (SLICC).

scientific article published on 9 November 2017

Evaluation of the pharmacokinetic equivalence and 54-week efficacy and safety of CT-P13 and innovator infliximab in Japanese patients with rheumatoid arthritis.

scientific article published on 4 March 2015

Fragmented hyaluronan induces transcriptional up-regulation of the multidrug resistance-1 gene in CD4+ T cells

scientific article published on 12 October 2006

Head-to-head comparison of the safety of tocilizumab and tumor necrosis factor inhibitors in rheumatoid arthritis patients (RA) in clinical practice: results from the registry of Japanese RA patients on biologics for long-term safety (REAL) registry

scientific article

Human urinary trypsin inhibitor bolus infusion improved severe interstitial pneumonia in mixed connective tissue disease

scientific article published in January 2005

IL-6-accelerated calcification by induction of ROR2 in human adipose tissue-derived mesenchymal stem cells is STAT3 dependent

scientific article published on 4 March 2014

IgG4-related Pleuritis with Elevated Adenosine Deaminase in Pleural Effusion: A Case Report

scientific article published on 9 March 2018

Incidence and risk factors for serious infection in patients with rheumatoid arthritis treated with tumor necrosis factor inhibitors: a report from the Registry of Japanese Rheumatoid Arthritis Patients for Longterm Safety

scientific article published on 15 April 2011

Induction of RANKL expression and osteoclast maturation by the binding of fibroblast growth factor 2 to heparan sulfate proteoglycan on rheumatoid synovial fibroblasts

scientific article published on 01 August 2004

Induction of hyperadiponectinemia following long-term treatment of patients with rheumatoid arthritis with infliximab (IFX), an anti-TNF-alpha antibody

scientific article

Involvement of Syk in pathology of systemic autoimmune disease

scientific article published on January 1, 2012

Iterative decomposition of water and fat with echo asymmetry and least‐squares estimation (IDEAL) of the wrist and finger at 3T: Comparison with chemical shift selective fat suppression images

scientific article published on August 21, 2012

Leflunomide inhibits PDK1/Akt pathway and induces apoptosis of human mast cells

scientific article published in November 2007

Low complements and high titre of anti-Sm antibody as predictors of histopathologically proven silent lupus nephritis without abnormal urinalysis in patients with systemic lupus erythematosus

scientific article published on 2 September 2014

Lymphocytic focus score is positively related to airway and interstitial lung diseases in primary Sjögren's syndrome

scientific article published on 01 March 2018

Mast cell-derived tryptase inhibits apoptosis of human rheumatoid synovial fibroblasts via rho-mediated signaling.

scientific article published in April 2010

Multicenter Double-Blind Randomized Controlled Trial to Evaluate the Effectiveness and Safety of Bortezomib as a Treatment for Refractory Systemic Lupus Erythematosus

scientific article published on 24 January 2018

No association between BDNF Val66Met polymorphism and emergence of psychiatric symptoms in systemic lupus erythematosus patients

scientific article published on June 16, 2011

No increased mortality in patients with rheumatoid arthritis treated with biologics: results from the biologics register of six rheumatology institutes in Japan

scientific article published on 17 October 2012

Opportunistic infections in patients with collagen disease

scientific article

Overcoming treatment unresponsiveness mediated by P-glycoprotein overexpression on lymphocytes in refractory active systemic lupus erythematosus

scientific article published on 01 January 2005

Pericarditis induced by prophylactic administration of isoniazid in a patient with rheumatoid arthritis

scientific article published on 20 October 2010

Peripheral Immunophenotyping Identifies Three Subgroups Based on T Cell Heterogeneity in Lupus Patients

scientific article published on 12 June 2017

Phenotypic Changes of Lymphocytes in Patients with Systemic Lupus Erythematosus Who Are in Longterm Remission After B Cell Depletion Therapy with Rituximab

scientific article published on December 15, 2010

Phenotypic changes of lymphocyte in a patient with IgG4-related disease after corticosteroid therapy

scientific article published on July 11, 2012

Plasma catecholamine metabolite levels and the activities of psychiatric symptoms in systemic lupus erythematosus

scientific article published on March 1, 2013

Pneumocystis jiroveci pneumonia in patients with rheumatoid arthritis treated with infliximab: a retrospective review and case-control study of 21 patients.

scientific article published on March 2009

Pneumocystis jirovecii pneumonia associated with etanercept treatment in patients with rheumatoid arthritis: a retrospective review of 15 cases and analysis of risk factors

scientific article published on 22 February 2012

Prophylaxis for Pneumocystis pneumonia in patients with rheumatoid arthritis treated with biologics, based on risk factors found in a retrospective study

scientific article published on 05 February 2014

Quantitative susceptibility mapping in patients with systemic lupus erythematosus: detection of abnormalities in normal-appearing basal ganglia

scientific article published in August 2015

Rapidly progressive glomerulonephritis after introduction of certolizumab pegol: a case report

scientific article published on 20 July 2020

Relevance of P-glycoprotein on CXCR4+ B cells to organ manifestation in highly active rheumatoid arthritis

scientific article

Remission induction by Raising the dose of Remicade in RA (RRRR) study: Rationale and study protocol for a randomized controlled trial comparing for sustained clinical remission after discontinuation of infliximab in patients with rheumatoid arthrit

scientific article

Retrospective clinical study on the notable efficacy and related factors of infliximab therapy in a rheumatoid arthritis management group in Japan (RECONFIRM)

scholarly article by Hisashi Yamanaka et al published 20 April 2007 in Modern Rheumatology

Retrospective clinical study on the notable efficacy and related factors of infliximab therapy in a rheumatoid arthritis management group in Japan (RECONFIRM)

scholarly article by Hisashi Yamanaka et al published 20 February 2007 in Modern Rheumatology

Retrospective clinical study on the notable efficacy and related factors of infliximab therapy in a rheumatoid arthritis management group in Japan: one-year clinical outcomes (RECONFIRM-2)

scientific article published on 19 February 2008

Retrospective clinical study on the notable efficacy and related factors of infliximab therapy in a rheumatoid arthritis management group in Japan: one-year outcome of joint destruction (RECONFIRM-2J).

scientific article published on 21 May 2008

Safety and efficacy of CT-P13 in Japanese patients with rheumatoid arthritis in an extension phase or after switching from infliximab.

scientific article

Safety and tolerability of sifalimumab, an anti-interferon-α monoclonal antibody, in Japanese patients with systemic lupus erythematosus: A multicenter, phase 2, open-label study

scientific article published on 25 March 2019

Safety, pharmacokinetics, and pharmacodynamics of epratuzumab in Japanese patients with moderate-to-severe systemic lupus erythematosus: Results from a phase 1/2 randomized study

scientific article published on 18 September 2015

Serum brain-derived neurotrophic factor levels as a novel biological marker for the activities of psychiatric symptoms in systemic lupus erythematosus

scientific article published in March 2010

Severe skin ulceration associated with Wegener's granulomatosis: successful treatment with hyperbaric oxygen and prostaglandin E1

scientific article published on 01 December 2003

Significance of nailfold videocapillaroscopy in patients with idiopathic inflammatory myopathies

scientific article published on 01 January 2019

Small GTP-binding protein Rho-mediated signaling promotes proliferation of rheumatoid synovial fibroblasts

scientific article

Small GTPase Rho signaling is involved in beta1 integrin-mediated up-regulation of intercellular adhesion molecule 1 and receptor activator of nuclear factor kappaB ligand on osteoblasts and osteoclast maturation

scientific article

Structural damages disturb functional improvement in patients with rheumatoid arthritis treated with etanercept

scholarly article by Yoshiya Tanaka et al published 8 September 2011 in Modern Rheumatology

Study on the safety and efficacy of tocilizumab, an anti-IL-6 receptor antibody, in patients with rheumatoid arthritis complicated with AA amyloidosis

scientific article published on 21 October 2013

Successful treatment of intravenous cyclophosphamide pulse therapy for lupus myelitis with urinary disturbance and acute confusional state

scientific article

Successful treatment of osteomalacia caused by renal tubular acidosis associated with Sjögren’s syndrome

scientific article published on June 28, 2012

Successful treatment of primary biliary cirrhosis with etanercept in a patient with rheumatoid arthritis

scientific article published on 23 June 2011

Systemic lupus erythematosus: prediction by MRI of the subsequent development of brain lesions

scientific article published on 01 May 2014

Tacrolimus, a calcineurin inhibitor, overcomes treatment unresponsiveness mediated by P-glycoprotein on lymphocytes in refractory rheumatoid arthritis

scientific article published on 15 January 2010

The REAL database reveals no significant risk of serious infection during treatment with a methotrexate dose of more than 8 mg/week in patients with rheumatoid arthritis

scientific article published on 11 February 2011

Thin-section chest CT findings in polymyalgia rheumatica: a comparison between with and without rheumatoid arthritis

scientific article published on 30 November 2015

Thin-section chest CT findings in systemic lupus erythematosus with antiphospholipid syndrome: A comparison with systemic lupus erythematosus without antiphospholipid syndrome

scientific article published on April 17, 2011

Time‐dependent increased risk for serious infection from continuous use of tumor necrosis factor antagonists over three years in patients with rheumatoid arthritis

scientific article published on 01 August 2012

Tomosynthesis of the wrist and hand in patients with rheumatoid arthritis: comparison with radiography and MRI

scientific article published on 01 February 2014

Transcriptional regulation of multidrug resistance-1 gene by interleukin-2 in lymphocytes

scientific article

Type I and II interferons commit to abnormal expression of chemokine receptor on B cells in patients with systemic lupus erythematosus

scientific article published on 19 December 2018

Usefulness of initial histological features for stratifying Sjogren's syndrome responders to mizoribine therapy

scientific article published on 11 August 2009

[Efficacy of tacrolimus for joint destruction in rheumatoid arthritis]

scientific article published on 01 April 2007

[New biologic and non biologic disease modifying anti-rheumatic drugs for rheumatoid arthritis].

scientific article published in June 2009

[Pneumocystis carinii pneumonia in patients with connective tissue diseases]

scientific article published on 01 August 2002

[Recent topics on new biological agents for treatment of rheumatoid arthritis]

scientific article published on 01 October 2008

[Targeting CD20 in rheumatoid arthritis]

scientific article published on 01 July 2007

beta1 integrin-mediated signaling induces intercellular adhesion molecule 1 and Fas on rheumatoid synovial cells and Fas-mediated apoptosis

scientific article published in May 2003