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List of works by Zhiqian Dong

A therapeutic combination of GPCR modulators that protects photoreceptors from degeneration

scientific article published on 21 November 2017

Conditional deletion of Des1 in the mouse retina does not impair the visual cycle in cones

scientific article published on 15 January 2019

Dephosphorylation by protein phosphatase 2A regulates visual pigment regeneration and the dark adaptation of mammalian photoreceptors.

scientific article published on 23 October 2017

Epigenetic hallmarks of age-related macular degeneration are recapitulated in a photosensitive mouse model

scientific article published on 21 July 2020

Expansion of first-in-class drug candidates that sequester toxic all-trans-retinal and prevent light-induced retinal degeneration

scientific article

Heterologous expression and purification of the serotonin type 4 receptor from transgenic mouse retina

scientific article

Insights into the pathogenesis of dominant retinitis pigmentosa associated with a D477G mutation in RPE65.

scientific article published on 12 April 2018

MicroRNA-processing Enzymes Are Essential for Survival and Function of Mature Retinal Pigmented Epithelial Cells in Mice

scientific article

Molecular pharmacodynamics of emixustat in protection against retinal degeneration

scientific article

Noninvasive two-photon microscopy imaging of mouse retina and retinal pigment epithelium through the pupil of the eye.

scientific article

Noninvasive two-photon optical biopsy of retinal fluorophores

scientific article published on 26 August 2020

Post-translational modifications of the serotonin type 4 receptor heterologously expressed in mouse rod cells

scientific article published on 20 December 2011

Protective Effect of a Locked Retinal Chromophore Analog against Light-Induced Retinal Degeneration

scientific article published on 17 July 2018

Publisher Correction: Restoration of visual function in adult mice with an inherited retinal disease via adenine base editing

scientific article published on 29 October 2020

QLT091001, a 9-cis-retinal analog, is well-tolerated by retinas of mice with impaired visual cycles

scientific article

Receptor MER Tyrosine Kinase Proto-oncogene (MERTK) Is Not Required for Transfer of Bis-retinoids to the Retinal Pigmented Epithelium

scientific article published on 14 November 2016

Restoration of visual function in adult mice with an inherited retinal disease via adenine base editing

scientific article published on 19 October 2020

Serum levels of lipid metabolites in age-related macular degeneration

scientific article

Synergistically acting agonists and antagonists of G protein-coupled receptors prevent photoreceptor cell degeneration

scientific article published on 26 July 2016

Systems pharmacology identifies drug targets for Stargardt disease-associated retinal degeneration

scientific article published on 15 November 2013

The selective estrogen receptor modulator raloxifene mitigates the effect of all-trans-retinal toxicity in photoreceptor degeneration

scientific article published on 09 May 2019

Two-photon imaging of the mammalian retina with ultrafast pulsing laser

scientific article published on 06 September 2018

Two-photon microscopy reveals early rod photoreceptor cell damage in light-exposed mutant mice

scientific article published on 24 March 2014