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List of works by Jaap Verweij

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Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial

scientific article
Progression-free survival in gastrointestinal stromal tumours with high-dose imatinib: randomised trial

scientific article
Phase I, Dose-Escalation Study of BKM120, an Oral Pan-Class I PI3K Inhibitor, in Patients With Advanced Solid Tumors

scientific article published on December 12, 2011
KIT mutations and dose selection for imatinib in patients with advanced gastrointestinal stromal tumours

scientific article
Pazopanib, a multikinase angiogenesis inhibitor, in patients with relapsed or refractory advanced soft tissue sarcoma: a phase II study from the European organisation for research and treatment of cancer-soft tissue and bone sarcoma group (EORTC stu

scientific article
Doxorubicin alone versus intensified doxorubicin plus ifosfamide for first-line treatment of advanced or metastatic soft-tissue sarcoma: a randomised controlled phase 3 trial.

scientific article
Lymphopenia as a prognostic factor for overall survival in advanced carcinomas, sarcomas, and lymphomas

scientific article published on 23 June 2009
Neo-adjuvant chemotherapy alone or with regional hyperthermia for localised high-risk soft-tissue sarcoma: a randomised phase 3 multicentre study

scientific article
Pharmacological effects of formulation vehicles : implications for cancer chemotherapy

scientific article published in January 2003
Outcome of patients with advanced gastro-intestinal stromal tumours crossing over to a daily imatinib dose of 800 mg after progression on 400 mg.

scientific article
Initial and late resistance to imatinib in advanced gastrointestinal stromal tumors are predicted by different prognostic factors: a European Organisation for Research and Treatment of Cancer-Italian Sarcoma Group-Australasian Gastrointestinal Trial

scientific article published in August 2005
The clinical toxicity profile of vascular endothelial growth factor (VEGF) and vascular endothelial growth factor receptor (VEGFR) targeting angiogenesis inhibitors; a review

scientific article published on 13 November 2006
Effects of St. John's wort on irinotecan metabolism

scientific article published in August 2002
Adjuvant chemotherapy with doxorubicin, ifosfamide, and lenograstim for resected soft-tissue sarcoma (EORTC 62931): a multicentre randomised controlled trial.

scientific article
Role of body surface area in dosing of investigational anticancer agents in adults, 1991-2001.

scientific article
Phase III Trial of Two Investigational Schedules of Ifosfamide Compared With Standard-Dose Doxorubicin in Advanced or Metastatic Soft Tissue Sarcoma: A European Organisation for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group Stud

article
Prognostic and predictive factors for outcome to first-line ifosfamide-containing chemotherapy for adult patients with advanced soft tissue sarcomas

article by Stefan Sleijfer et al published January 2010 in European Journal of Cancer
Soft tissue sarcomas of adults: state of the translational science.

scientific article
Chronic imatinib mesylate exposure leads to reduced intracellular drug accumulation by induction of the ABCG2 (BCRP) and ABCB1 (MDR1) drug transport pumps

scientific article published on 9 July 2005
Diflomotecan pharmacokinetics in relation to ABCG2 421C>A genotype

scientific article
ABCG2 pharmacogenetics: ethnic differences in allele frequency and assessment of influence on irinotecan disposition

scientific article published in September 2004
Drug transporters of platinum-based anticancer agents and their clinical significance

scientific article
Imatinib pharmacokinetics in patients with gastrointestinal stromal tumour: a retrospective population pharmacokinetic study over time. EORTC Soft Tissue and Bone Sarcoma Group

scientific article published on 9 December 2004
Drug transporters and imatinib treatment: implications for clinical practice

scientific article
Individual patient data analysis to assess modifications to the RECIST criteria.

scientific article
Pharmacogenetics of ABCG2 and adverse reactions to gefitinib

scientific article published on 01 December 2006
Clinical pharmacokinetics of docetaxel : recent developments

scientific article
Irinotecan pathway genotype analysis to predict pharmacokinetics

scientific journal article
(Pre-)clinical pharmacology and activity of pazopanib, a novel multikinase angiogenesis inhibitor

scientific article
Update of phase I study of imatinib (STI571) in advanced soft tissue sarcomas and gastrointestinal stromal tumors: a report of the EORTC Soft Tissue and Bone Sarcoma Group

scientific article published in September 2002
Interaction of Cisplatin with the human organic cation transporter 2.

scientific article published in June 2008
DOG1 and CD117 are the antibodies of choice in the diagnosis of gastrointestinal stromal tumours

scientific article
Evaluation of alternate size descriptors for dose calculation of anticancer drugs in the obese

scientific article
Effect of ABCG2 genotype on the oral bioavailability of topotecan

scientific article published on 11 June 2005
Outcome of patients with platelet-derived growth factor receptor alpha-mutated gastrointestinal stromal tumors in the tyrosine kinase inhibitor era.

scientific article
Prediction of irinotecan pharmacokinetics by use of cytochrome P450 3A4 phenotyping probes

scientific article published in November 2004
Factors affecting cytochrome P-450 3A activity in cancer patients.

scientific article published in December 2004
Complete longitudinal analyses of the randomized, placebo-controlled, phase III trial of sunitinib in patients with gastrointestinal stromal tumor following imatinib failure

scientific article
Mechanisms of resistance to anticancer drugs: the role of the polymorphic ABC transporters ABCB1 and ABCG2.

scientific article
Complementary and alternative medicine during cancer treatment: beyond innocence

scientific article
A retrospective analysis of antitumour activity with trabectedin in translocation-related sarcomas

scientific article
Comparative pharmacokinetics of weekly and every-three-weeks docetaxel.

scientific article
Alternative drug formulations of docetaxel: a review

scientific article published in February 2007
Towards new methods for the determination of dose limiting toxicities and the assessment of the recommended dose for further studies of molecularly targeted agents--dose-Limiting Toxicity and Toxicity Assessment Recommendation Group for Early Trials

scientific article
Pharmacology of topoisomerase I inhibitors irinotecan (CPT-11) and topotecan

scientific article published in June 2002
Effect of cytochrome P450 3A4 inhibition on the pharmacokinetics of docetaxel

scientific article published in May 2004
Biologic and Clinical Activity of Tivozanib (AV-951, KRN-951), a Selective Inhibitor of VEGF Receptor-1, -2, and -3 Tyrosine Kinases, in a 4-Week-On, 2-Week-Off Schedule in Patients with Advanced Solid Tumors

scientific article published on October 5, 2011
Phase I pharmacokinetic and pharmacodynamic study of the aurora kinase inhibitor danusertib in patients with advanced or metastatic solid tumors

scientific article published on 21 September 2009
Association of enzyme and transporter genotypes with the pharmacokinetics of imatinib

scientific article published on August 2006
Mapatumumab, a fully human agonistic monoclonal antibody that targets TRAIL-R1, in combination with gemcitabine and cisplatin: a phase I study.

scientific article

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