List of works - Maxim V Frolov

A cell atlas of adult muscle precursors uncovers early events in fibre-type divergence in Drosophila

scientific article published on 19 August 2020

A non-catalytic scaffolding activity of hexokinase 2 contributes to EMT and metastasis

scientific article published on 16 February 2022

Amalgam regulates the receptor tyrosine kinase pathway through Sprouty in glial cell development

scientific article published on 02 September 2020

An intronic microRNA links Rb/E2F and EGFR signaling

scientific article

Cell cycle-dependent and cell cycle-independent control of transcription by the Drosophila E2F/RB pathway

scientific article

Cell-Autonomous versus Systemic Akt Isoform Deletions Uncovered New Roles for Akt1 and Akt2 in Breast Cancer

scientific article published on 09 September 2020

Combined inactivation of pRB and hippo pathways induces dedifferentiation in the Drosophila retina

scientific article

Context-dependent requirement for dE2F during oncogenic proliferation

scientific article

Cooperation between dE2F1 and Yki/Sd defines a distinct transcriptional program necessary to bypass cell cycle exit

scientific article (publication date: 15 February 2011)

Distinct mechanisms of E2F regulation by Drosophila RBF1 and RBF2

scientific article

Drosophila E2F1 has context-specific pro- and antiapoptotic properties during development

scientific article published on October 2005

Drosophila GAGA factor is required for full activation of the dE2f1-Yki/Sd transcriptional program

scientific article

E2F function in muscle growth is necessary and sufficient for viability in Drosophila

scientific article published on 29 January 2016

E2F/DP Prevents Cell-Cycle Progression in Endocycling Fat Body Cells by Suppressing dATM Expression.

scientific article

G1 cyclin-dependent kinases are insufficient to reverse dE2F2-mediated repression

scientific article published on March 2003

Loss of E2F compromises mitochondrial function and protects cells from irradiation-induced apoptosis in Drosophila

Loss of dE2F compromises mitochondrial function

scientific article (publication date: 25 November 2013)

Microprocessor Recruitment to Elongating RNA Polymerase II Is Required for Differential Expression of MicroRNAs

scientific article published on September 2017

Molecular mechanisms of E2F-dependent activation and pRB-mediated repression

scientific article

Mosaic genetic screen for suppressors of the de2f1 mutant phenotype in Drosophila

scientific article published on 22 June 2009

Mutation of the DEAD-box helicase belle downregulates the cyclin-dependent kinase inhibitor Dacapo

scientific article

Notch-dependent expression of the archipelago ubiquitin ligase subunit in the Drosophila eye ⬇️

scientific article published on December 9, 2010

Novel regulation and functional interaction of polycistronic miRNAs

scientific article

Rbf Activates the Myogenic Transcriptional Program to Promote Skeletal Muscle Differentiation

Retinoblastoma family 2 is required in vivo for the tissue-specific repression of dE2F2 target genes

scientific article published on 29 September 2005

Single cell RNA-sequencing identifies a metabolic aspect of apoptosis in Rbf mutant

scientific article published in Nature Communications

Single-cell transcriptional changes associated with drug tolerance and response to combination therapies in cancer

scientific article published on 12 March 2021

Specific role of the SR protein splicing factor B52 in cell cycle control in Drosophila

scientific article published on May 2006

The archipelago tumor suppressor gene limits rb/e2f-regulated apoptosis in developing Drosophila tissues

scientific article published on 03 September 2009

The diverse roles of RNA helicases in RNAi

scientific article

Tuberous Sclerosis Complex 1 Regulates dE2F1 Expression during Development and Cooperates with RBF1 to Control Proliferation and Survival ⬇️

scientific article published on August 19, 2010

dDP is needed for normal cell proliferation

scientific article published on April 2005

dE2F2-independent rescue of proliferation in cells lacking an activator dE2F1.

scientific article

mir-11 limits the proapoptotic function of its host gene, dE2f1

scientific article

List of works by Maxim V Frolov

A cell atlas of adult muscle precursors uncovers early events in fibre-type divergence in Drosophila

A non-catalytic scaffolding activity of hexokinase 2 contributes to EMT and metastasis

Amalgam regulates the receptor tyrosine kinase pathway through Sprouty in glial cell development

An intronic microRNA links Rb/E2F and EGFR signaling

Cell cycle-dependent and cell cycle-independent control of transcription by the Drosophila E2F/RB pathway

Cell-Autonomous versus Systemic Akt Isoform Deletions Uncovered New Roles for Akt1 and Akt2 in Breast Cancer

Combined inactivation of pRB and hippo pathways induces dedifferentiation in the Drosophila retina

Context-dependent requirement for dE2F during oncogenic proliferation

Cooperation between dE2F1 and Yki/Sd defines a distinct transcriptional program necessary to bypass cell cycle exit

Distinct mechanisms of E2F regulation by Drosophila RBF1 and RBF2

Drosophila E2F1 has context-specific pro- and antiapoptotic properties during development

Drosophila GAGA factor is required for full activation of the dE2f1-Yki/Sd transcriptional program

E2F function in muscle growth is necessary and sufficient for viability in Drosophila

E2F/DP Prevents Cell-Cycle Progression in Endocycling Fat Body Cells by Suppressing dATM Expression.

G1 cyclin-dependent kinases are insufficient to reverse dE2F2-mediated repression

Loss of E2F compromises mitochondrial function and protects cells from irradiation-induced apoptosis in Drosophila

Loss of dE2F compromises mitochondrial function

Microprocessor Recruitment to Elongating RNA Polymerase II Is Required for Differential Expression of MicroRNAs

Molecular mechanisms of E2F-dependent activation and pRB-mediated repression

Mosaic genetic screen for suppressors of the de2f1 mutant phenotype in Drosophila

Mutation of the DEAD-box helicase belle downregulates the cyclin-dependent kinase inhibitor Dacapo

Notch-dependent expression of the archipelago ubiquitin ligase subunit in the Drosophila eye ⬇️

Novel regulation and functional interaction of polycistronic miRNAs

Rbf Activates the Myogenic Transcriptional Program to Promote Skeletal Muscle Differentiation

Retinoblastoma family 2 is required in vivo for the tissue-specific repression of dE2F2 target genes

Single cell RNA-sequencing identifies a metabolic aspect of apoptosis in Rbf mutant

Single-cell transcriptional changes associated with drug tolerance and response to combination therapies in cancer

Specific role of the SR protein splicing factor B52 in cell cycle control in Drosophila

The archipelago tumor suppressor gene limits rb/e2f-regulated apoptosis in developing Drosophila tissues

The diverse roles of RNA helicases in RNAi

Tuberous Sclerosis Complex 1 Regulates dE2F1 Expression during Development and Cooperates with RBF1 to Control Proliferation and Survival ⬇️

dDP is needed for normal cell proliferation

dE2F2-independent rescue of proliferation in cells lacking an activator dE2F1.

mir-11 limits the proapoptotic function of its host gene, dE2f1