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List of works by Elizabeth D. Getzoff

A Self-Assisting Protein Folding Model for Teaching Structural Molecular Biology

scientific article

ALS mutants of human superoxide dismutase form fibrous aggregates via framework destabilization

scientific article

ATP binding turns plant cryptochrome into an efficient natural photoswitch

scientific article

Aggregation propensities of superoxide dismutase G93 hotspot mutants mirror ALS clinical phenotypes

scientific article

Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase

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Amyotrophic lateral sclerosis: update and new developments.

scientific article

Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase

scientific article

Anticipatory active-site motions and chromophore distortion prime photoreceptor PYP for light activation

scientific article

Biphasic coupling of neuronal nitric oxide synthase phosphorylation to the NMDA receptor regulates AMPA receptor trafficking and neuronal cell death.

scientific article published in March 2007

C-terminal tail residue Arg1400 enables NADPH to regulate electron transfer in neuronal nitric-oxide synthase

scientific article

Cloning, expression, and characterization of a nitric oxide synthase protein from Deinococcus radiodurans

scientific article

Computational reconstruction of multidomain proteins using atomic force microscopy data

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Conformational changes in nitric oxide synthases induced by chlorzoxazone and nitroindazoles: crystallographic and computational analyses of inhibitor potency

scientific article

Copper-based pulsed dipolar ESR spectroscopy as a probe of protein conformation linked to disease states

scientific article

Crystallographic structures of Discosoma red fluorescent protein with immature and mature chromophores: linking peptide bond trans-cis isomerization and acylimine formation in chromophore maturation.

scientific article published in July 2005

CysG structure reveals tetrapyrrole-binding features and novel regulation of siroheme biosynthesis

scientific article published in December 2003

Defining the role of arginine 96 in green fluorescent protein fluorophore biosynthesis

scientific article published in December 2005

Detection of distinct α-helical rearrangements of cyclobutane pyrimidine dimer photolyase upon substrate binding by Fourier transform infrared spectroscopy

scientific article

Direct observation of a photoinduced radical pair in a cryptochrome blue-light photoreceptor

scientific article

Distinct dimer interaction and regulation in nitric-oxide synthase types I, II, and III.

scientific article published on 4 June 2002

Early abscisic acid signal transduction mechanisms: newly discovered components and newly emerging questions.

scientific article published on August 2010

Electron nuclear double resonance differentiates complementary roles for active site histidines in (6-4) photolyase.

scientific article

Erratum to “ALS Mutants of Human Superoxide Dismutase form Fibrous Aggregates via Framework Destabilization” [J. Mol. Biol. 332 (2003) 601–615]

scholarly article published in Journal of Molecular Biology

Eukaryotic Class II Cyclobutane Pyrimidine Dimer Photolyase Structure Reveals Basis for Improved Ultraviolet Tolerance in Plants

scientific article

FRET-based reporters for the direct visualization of abscisic acid concentration changes and distribution in Arabidopsis

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FTIR Study of Light-Dependent Activation and DNA Repair Processes of (6–4) Photolyase

scientific article published on April 15, 2011

FTIR study of CPD photolyase with substrate in single strand DNA

scientific article published on 13 February 2015

Flavin adenine dinucleotide chromophore charge controls the conformation of cyclobutane pyrimidine dimer photolyase α-helices

scientific article published on 09 September 2014

Fourier-Transform Infrared Study of the Photoactivation Process of Xenopus (6–4) Photolyase

scientific article published on July 13, 2012

Functional Conversion of CPD and (6-4) Photolyases by Mutation

scientific article

Functional motifs in the (6-4) photolyase crystal structure make a comparative framework for DNA repair photolyases and clock cryptochromes

scientific article

Going green: phytohormone mimetics for drought rescue

scientific article published on November 2013

Identification of a flavin mononucleotide module residue critical for activity of inducible nitrite oxide synthase

scientific article published on 14 October 2009

Identification of a new cryptochrome class. Structure, function, and evolution

scientific article

Insights into Lou Gehrig's disease from the structure and instability of the A4V mutant of human Cu,Zn superoxide dismutase

scientific article

Interdomain engineered disulfide bond permitting elucidation of mechanisms of inactivation of coagulation factor Va by activated protein C

scientific article

Key Dynamics of Conserved Asparagine in a Cryptochrome/Photolyase Family Protein by Fourier Transform Infrared Spectroscopy

scientific article published on October 19, 2010

Light-Induced Conformational Change and Product Release in DNA Repair by (6−4) Photolyase

scientific article published on January 27, 2011

Light-induced activation of class II cyclobutane pyrimidine dimer photolyases

scientific article published on 15 March 2010

Light-induced conformational changes in full-length Arabidopsis thaliana cryptochrome

scientific article

Luminescent ruthenium(II)- and rhenium(I)-diimine wires bind nitric oxide synthase

scientific article published in April 2005

Lys842 in neuronal nitric-oxide synthase enables the autoinhibitory insert to antagonize calmodulin binding, increase FMN shielding, and suppress interflavin electron transfer

scientific article

MDB: the Metalloprotein Database and Browser at The Scripps Research Institute

scientific article

Mechanism and energetics of green fluorescent protein chromophore synthesis revealed by trapped intermediate structures

scientific article

Nickel Superoxide Dismutase Structure and Mechanism†

scientific article (publication date: June 2004)

Nitric-oxide Synthase Forms N-NO-pterin and S-NO-Cys: IMPLICATIONS FOR ACTIVITY, ALLOSTERY, AND REGULATION

scientific article

Origin of light-induced spin-correlated radical pairs in cryptochrome.

scientific article published on 4 August 2010

PASsing a signal: low carbs, less protein

scientific article published on 01 November 2002

Photoisomerization and proton transfer in photoactive yellow protein

scientific article published in July 2003

Plant UVR8 photoreceptor senses UV-B by tryptophan-mediated disruption of cross-dimer salt bridges

scientific article

Radical reactions of nitric oxide synthases.

scientific article

Reaction dynamics of the UV-B photosensor UVR8.

scientific article published in May 2015

Recognition and reaction mechanisms of the (6-4) photolyase as determined by using a (6-4) photoproduct analog

scientific article published in January 2009

Resistance of the target islet tissue to autoimmune destruction contributes to genetic susceptibility in Type 1 diabetes

scientific article published on 25 January 2007

Role of the carbonyl group of the (6-4) photoproduct in the (6-4) photolyase reaction

scientific article

Science education. Educating future scientists

scientific article

Self-Assembly of the Cephalopod Protein Reflectin.

scientific article published on 25 July 2016

Single Hydrogen Bond Donation from Flavin N5 to Proximal Asparagine Ensures FAD Reduction in DNA Photolyase

scientific article published on 22 March 2016

Spectroscopic studies on a novel intramolecular hydrogen bond within the (6-4) photoproduct

scientific article published in January 2007

Structural Changes of the Active Center during the Photoactivation of Xenopus (6-4) Photolyase

scientific article published on 31 December 2015

Structural Characterization of Zinc-deficient Human Superoxide Dismutase and Implications for ALS

scientific article

Structural Tuning of the Fluorescent Protein iLOV for Improved Photostability

scientific article

Structural basis for endothelial nitric oxide synthase binding to calmodulin

scientific article (publication date: 17 February 2003)

Structural basis for isozyme-specific regulation of electron transfer in nitric-oxide synthase.

scientific article

Structural chemistry of a green fluorescent protein Zn biosensor

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Structural evidence for an enolate intermediate in GFP fluorophore biosynthesis.

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Structural insights into protein-metal ion partnerships.

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Structural mechanism of abscisic acid binding and signaling by dimeric PYR1.

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Structural role of two histidines in the (6-4) photolyase reaction

scientific article published on 22 December 2015

Structural, Functional, and Immunogenic Insights on Cu,Zn Superoxide Dismutase Pathogenic Virulence Factors from Neisseria meningitidis and Brucella abortus

scientific article

Structure of tetrahydrobiopterin tunes its electron transfer to the heme-dioxy intermediate in nitric oxide synthase.

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Structure of the fibre-forming protein pilin at 2.6 A resolution

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Structure/function studies on a S-adenosyl-L-methionine-dependent uroporphyrinogen III C methyltransferase (SUMT), a key regulatory enzyme of tetrapyrrole biosynthesis

scientific article published in November 2004

Superoxide dismutase from the eukaryotic thermophile Alvinella pompejana: structures, stability, mechanism, and insights into amyotrophic lateral sclerosis

scientific article

Surface charge interactions of the FMN module govern catalysis by nitric-oxide synthase

scientific article published on 25 September 2006

Tetrameric architecture of the circadian clock protein KaiB. A novel interface for intermolecular interactions and its impact on the circadian rhythm

scientific article

The Electronic State of Flavoproteins: Investigations with Proton Electron-Nuclear Double Resonance

scientific article published on January 2010

The case of the missing ring: radical cleavage of a carbon-carbon bond and implications for GFP chromophore biosynthesis

scientific article

The three nitric-oxide synthases differ in their kinetics of tetrahydrobiopterin radical formation, heme-dioxy reduction, and arginine hydroxylation

scientific article published on 4 January 2005

Type IV pilin structure and assembly: X-ray and EM analyses of Vibrio cholerae toxin-coregulated pilus and Pseudomonas aeruginosa PAK pilin

scientific article (publication date: May 2003)

Understanding GFP chromophore biosynthesis: controlling backbone cyclization and modifying post-translational chemistry.

scientific article published in February 2005

Understanding GFP posttranslational chemistry: structures of designed variants that achieve backbone fragmentation, hydrolysis, and decarboxylation.

scientific article published in April 2006

Unexpected electron transfer in cryptochrome identified by time-resolved EPR spectroscopy.

scientific article

Variable electron transfer pathways in an amphibian cryptochrome: tryptophan versus tyrosine-based radical pairs

scientific article published on 19 February 2013