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List of works by Deborah J. Clegg

17α-Estradiol Alleviates Age-related Metabolic and Inflammatory Dysfunction in Male Mice Without Inducing Feminization

scientific article

A Peripheral CB1R Antagonist Increases Lipolysis, Oxygen Consumption Rate, and Markers of Beiging in 3T3-L1 Adipocytes Similar to RIM, Suggesting that Central Effects Can Be Avoided

scientific article published on 10 September 2020

A Universally Accepted Definition of Gender Will Positively Impact Societal Understanding, Acceptance, and Appropriateness of Health Care

scientific article published on 19 May 2020

A potential role for the hippocampus in energy intake and body weight regulation

scientific article

A role for syndecan-3 in the melanocortin regulation of energy balance

scientific article

Acetaminophen normalizes glucose homeostasis in mouse models for diabetes

scientific article published on 15 December 2007

Achieving the Benefits of a High-Potassium, Paleolithic Diet, Without the Toxicity

scientific article published on 3 March 2016

Activation of NPRs and UCP1-independent pathway following CB1R antagonist treatment is associated with adipose tissue beiging in fat-fed male dogs

scientific article published on 25 June 2019

Activation of estrogen receptor alpha induces beiging of adipocytes

scientific article published on 15 September 2018

Activation of natriuretic peptides and the sympathetic nervous system following Roux-en-Y gastric bypass is associated with gonadal adipose tissues browning

scientific article published on 3 March 2015

Acute third ventricular administration of insulin decreases food intake in two paradigms

scientific article published in May 2002

Adrenalectomy alters the sensitivity of the central nervous system melanocortin system.

scientific article published in December 2003

Altered Prostaglandin Signaling as a Cause of Thiazide-Induced Hyponatremia

scientific article published on 28 February 2018

Altered feeding responses in mice with targeted disruption of the dopamine-3 receptor gene

scientific article published in February 2003

An Emerging Role of Natriuretic Peptides: Igniting the Fat Furnace to Fuel and Warm the Heart

scientific article

An integrated view of sex differences in metabolic physiology and disease

scientific article published on 21 June 2018

Apolipoprotein A-IV interacts synergistically with melanocortins to reduce food intake.

scientific article

Ascent to altitude as a weight loss method: The good and bad of hypoxia inducible factor activation ⬇️

scientific article published on October 15, 2013

Blood pressure lowering and potassium intake

scientific article published on 12 August 2020

Brain apolipoprotein E: an important regulator of food intake in rats

scientific article published on 16 June 2008

C75 inhibits food intake by increasing CNS glucose metabolism

scientific article published in May 2003

Cardiovascular Benefits of a Diet Enriched in Fruits and Vegetables

scientific article published on 17 April 2019

Central insulin potentiates eating elicited by 2-deoxy-D-glucose

scientific article

Challenges in Treating Cardiovascular Disease: Restricting Sodium and Managing Hyperkalemia

scientific article published in August 2017

Chronic High Fat Diet Consumption Impairs Metabolic Health of Male Mice

scientific article published on January 2014

Chronic food restriction and reduced dietary fat: risk factors for bouts of overeating

scientific article published on 19 September 2005

Clinical Management of Hyperkalemia

scientific article published on 04 November 2020

Clinical endocrinology and metabolism. Regulation of energy homeostasis by peripheral signals

scientific article

Comparison of central and peripheral administration of C75 on food intake, body weight, and conditioned taste aversion.

scientific article published in November 2002

Comparison of hydrogenated vegetable shortening and nutritionally complete high-fat diet on limited access-binge behavior in rats

scientific article

Consumption of a high-fat diet alters the homeostatic regulation of energy balance

scientific article

Consumption of a high-fat diet induces central insulin resistance independent of adiposity

scientific article

Contributions of the hippocampus and medial prefrontal cortex to energy and body weight regulation

scientific article published on March 2009

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

Determinants of body fat distribution in humans may provide insight about obesity-related health risks

scientific article published on 10 August 2018

Diabetic ketoacidosis, sodium glucose transporter-2 inhibitors and the kidney

scientific article published on 10 May 2016

Diagnosis and treatment of hyperkalemia

scientific article published in December 2017

Diet-induced glucose homeostasis dysregulation is enhanced by taurine supplementation in ovariectomized mice

scientific article published on 27 December 2017

Diet-microbiome interactions in cancer treatment: Opportunities and challenges for precision nutrition in cancer

scientific article published in 2022

Dietary ketosis enhances memory in mild cognitive impairment ⬇️

scientific article published on December 3, 2010

Differential sensitivity to central leptin and insulin in male and female rats

scientific article published in March 2003

Distinct Hypothalamic Neurons Mediate Estrogenic Effects on Energy Homeostasis and Reproduction

scientific article published on 01 May 2019

Distinct hypothalamic neurons mediate estrogenic effects on energy homeostasis and reproduction

scientific article published on October 2011

Do estrogens enhance activation of brown and beiging of adipose tissues?

scientific article

ERα upregulates Phd3 to ameliorate HIF-1 induced fibrosis and inflammation in adipose tissue

scientific article

Eating elicited by orexin-a, but not melanin-concentrating hormone, is opioid mediated

scientific article

Effects of ERβ and ERα on OVX-induced changes in adiposity and insulin resistance

scientific article published on 01 April 2020

Effects of an estrogen receptor α variant

scientific article published on October 2013

Electrolyte Disturbances in Patients with Chronic Alcohol-Use Disorder

scientific article published in October 2017

Electrolyte and Acid-Base Disturbances in Patients with Diabetes Mellitus

scientific article published on August 2015

Electrolyte and Acid–Base Disturbances in Diabetes Mellitus

scientific article published on 01 December 2015

Endocannabinoid Receptor-1 and Sympathetic Nervous System Mediate the Beneficial Metabolic Effects of Gastric Bypass

scientific article published on 01 October 2020

Estradiol stimulates adipogenesis and Slc2a4/GLUT4 expression via ESR1-mediated activation of CEBPA

scientific article published on 14 May 2019

Estradiol-dependent decrease in the orexigenic potency of ghrelin in female rats

scientific article published on 24 January 2007

Estrogen Receptor-α in the Medial Amygdala Prevents Stress-Induced Elevations in Blood Pressure in Females.

scientific article published on 18 April 2016

Estrogen and leptin regulation of endocrinological features of anorexia nervosa

scientific article

Estrogen receptor-α in medial amygdala neurons regulates body weight

scientific article

Estrogens modulate ventrolateral ventromedial hypothalamic glucose-inhibited neurons

scientific article published on 20 August 2016

Estrogens stimulate serotonin neurons to inhibit binge-like eating in mice.

scientific article

Evaluation of the lack of anorectic effect of intracerebroventricular insulin in rats

scientific article published on 28 October 2009

Exposure to elevated levels of dietary fat attenuates psychostimulant reward and mesolimbic dopamine turnover in the rat.

scientific article published on December 2008

Female Sex and Gender in Lung/Sleep Health and Disease. Increased Understanding of Basic Biological, Pathophysiological, and Behavioral Mechanisms Leading to Better Health for Female Patients with Lung Disease

article

Fluid overload as a therapeutic target for the preservative management of chronic kidney disease

scientific article published on 01 January 2020

G-protein-coupled estrogen receptor 1 is anatomically positioned to modulate synaptic plasticity in the mouse hippocampus.

scientific article

GM-CSF action in the CNS decreases food intake and body weight

scientific article

GPR30 deficiency causes increased bone mass, mineralization, and growth plate proliferative activity in male mice

scientific article

GPR30 regulates diet-induced adiposity in female mice and adipogenesis in vitro

scientific article published on 04 October 2016

Gastric Bypass Surgery but not Caloric Restriction Improves Reproductive Function in Obese Mice

scientific article

Gastrointestinal potassium binding in hemodialysis

scientific article published on 01 November 2020

Gender Differences in the Control of Energy Homeostasis ⬇️

scientific article published on November 1, 2003

Genetic evidence of assortative mating in humans

article

Genetic rescue of nonclassical ERα signaling normalizes energy balance in obese Erα-null mutant mice

scientific article

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile

scientific article published on 26 June 2011

Gonadal dysfunction in chronic kidney disease

scientific article

Gonadal hormones determine sensitivity to central leptin and insulin

scientific article published in April 2006

Hippocampal lesions impair retention of discriminative responding based on energy state cues

scientific article

Hippocampal lipoprotein lipase regulates energy balance in rodents

scientific article

Hyperchloremic normal gap metabolic acidosis

scientific article published on 24 July 2019

Hyperkalemia

scientific article published on 01 December 2015

Hyperkalemia across the Continuum of Kidney Function

scientific article published on 7 November 2017

Hypothalamic PGC-1α protects against high-fat diet exposure by regulating ERα.

scientific article

Hypothalamic proinflammatory lipid accumulation, inflammation, and insulin resistance in rats fed a high-fat diet

scientific article published on 30 December 2008

Imaging Metabolically Active Fat: A Literature Review and Mechanistic Insights ⬇️

scientific article published on 05 November 2019

Impact of Dietary Potassium Restrictions in CKD on Clinical Outcomes: Benefits of a Plant-Based Diet

scientific article published on 15 June 2020

Impact of Estrogens and Estrogen Receptor Alpha (ESR1) in Brain Lipid Metabolism

scientific article published on 6 March 2018

Impaired estrogen receptor action in the pathogenesis of the metabolic syndrome

scientific article published on 29 May 2015

Implication of the melanocortin-3 receptor in the regulation of food intake.

scientific article published on January 2011

Importance of extranuclear estrogen receptor-alpha and membrane G protein-coupled estrogen receptor in pancreatic islet survival

scientific article published on 08 July 2009

Increased dietary fat attenuates the anorexic effects of intracerebroventricular injections of MTII

scientific article published on 01 July 2003

Insulin activation of phosphatidylinositol 3-kinase in the hypothalamic arcuate nucleus: a key mediator of insulin-induced anorexia

scientific article published in February 2003

Insulin and leptin as adiposity signals.

scientific article published on January 2004

Insulin and leptin combine additively to reduce food intake and body weight in rats

scientific article published in June 2002

Intraventricular (i3vt) ghrelin increases food intake in fatty Zucker rats

scientific article published on 28 December 2006

Intraventricular insulin and leptin reduce food intake and body weight in C57BL/6J mice

scientific article published on 18 September 2006

Intraventricular melanin-concentrating hormone stimulates water intake independent of food intake

scientific article published in February 2003

JAMA PATIENT PAGE. Dietary Guidelines for Americans--Eat Less Fat.

scientific article

JAMA PATIENT PAGE. Dietary Guidelines for Americans--Eat Less Salt

scientific article

JAMA PATIENT PAGE. Dietary Guidelines for Americans--Eat Less Sugar

scientific article published on 01 March 2016

Lacking of estradiol reduces insulin exocytosis from pancreatic β-cells and increases hepatic insulin degradation.

scientific article

Learned meal initiation attenuates the anorexic effects of the melanocortin agonist MTII.

scientific article published in November 2003

Leptin Signaling Is Not Required for Anorexigenic Estradiol Effects in Female Mice

scientific article published on 3 March 2016

Leptin regulates energy balance and motivation through action at distinct neural circuits

scientific article

Let Them Eat Healthy: Can Emerging Potassium Binders Help Overcome Dietary Potassium Restrictions in Chronic Kidney Disease?

scientific article published on 05 March 2020

Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in mice

scientific article

Maternal high-fat diet is associated with impaired fetal lung development

scientific article

Metabolic control by S6 kinases depends on dietary lipids

scientific article (publication date: 2012)

Metabolic impact of sex hormones on obesity

scientific article

Minireview: The Year in Review of Estrogen Regulation of Metabolism ⬇️

scientific article published on October 9, 2012

Myocardial steatosis impairs left ventricular diastolic–systolic coupling in healthy humans

scientific article published in 2023

New insights into the molecular mechanisms underlying effects of estrogen on cholesterol gallstone formation.

scientific article published on 06 July 2009

Novel functions of orexigenic hypothalamic peptides: from genes to behavior

scientific article published on September 2008

Obesity and cancer--mechanisms underlying tumour progression and recurrence

scientific article

Obesity: its influence on breast cancer susceptibility

scientific article published on 01 July 2006

Oestrogen signalling in white adipose progenitor cells inhibits differentiation into brown adipose and smooth muscle cells

scientific article published on 21 October 2014

Oestrogens, adipose tissues and environmental exposures influence obesity and diabetes across the lifecycle

scholarly article

Over-the-counter analgesics normalize blood glucose and body composition in mice fed a high fat diet

scientific article published on 7 May 2008

Overweight postmenopausal women with different plasma estradiol concentrations present with a similar pattern of energy expenditure and substrate oxidation rate before and after a fatty meal challenge

scientific article published on 2 June 2016

Oxygen sensing and metabolic homeostasis

scientific article

PI3K in the ventromedial hypothalamic nucleus mediates estrogenic actions on energy expenditure in female mice

scientific article

Palmitic acid mediates hypothalamic insulin resistance by altering PKC-q subcellular localization in rodents

scholarly article by Stephen C. Benoit et al published 1 January 2010 in Journal of Clinical Investigation

Palmitic acid mediates hypothalamic insulin resistance by altering PKC-theta subcellular localization in rodents

scientific article

Palmitic acid mediates hypothalamic insulin resistance by altering PKC-θ subcellular localization in rodents.

scientific article

Palmitic acid reduces the autophagic flux in hypothalamic neurons by impairing autophagosome-lysosome fusion and endolysosomal dynamics

scientific article published on 25 July 2020

Physiology and Pathophysiology of Potassium Homeostasis: Core Curriculum 2019

scientific article published on 19 June 2019

Physiology and pathophysiology of potassium homeostasis

scientific article

Plant-Based Diets in CKD

scientific article published on 26 December 2018

Potassium binding for conservative and preservative management of chronic kidney disease

scientific article published on 01 January 2020

Reduced anorexic effects of insulin in obesity-prone rats fed a moderate-fat diet.

scientific article published on 16 December 2004

Regulatory role of G protein-coupled estrogen receptor for vascular function and obesity

scientific article published on 29 January 2009

Renal Considerations in the Treatment of Hypertension

scientific article published on 24 January 2018

Renal Denervation Reverses Hepatic Insulin Resistance Induced by High-Fat Diet

scientific article published on 5 August 2016

SEX MATTERS - COVID-19 IN KIDNEY TRANSPLANTATION

scientific article published on 04 January 2021

SGLT2 Inhibition and Kidney Potassium Homeostasis

scientific article published on 28 August 2023

Salicylate Toxicity

scientific article published on 01 June 2020

Salicylate Toxicity. Reply

scientific article published on 01 September 2020

Set points, settling points and some alternative models: theoretical options to understand how genes and environments combine to regulate body adiposity

scientific article published on November 2011

Sex Hormones and Cardiometabolic Health: Role of Estrogen and Estrogen Receptors.

scientific article published on 17 February 2017

Sex and Gender: Critical Variables in Pre-Clinical and Clinical Medical Research

scientific article

Sex and Gender: Critical Variables in Pre-Clinical and Clinical Medical Research

scientific article published on 13 September 2016

Sex and media: Considerations for cell culture studies

scientific article published on 27 July 2018

Sex, Gender, and Transgender: Metabolic Impact of Cross Hormone Therapy

scientific article published in January 2017

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits

scientific article

Sexual differences in the control of energy homeostasis

scientific article published on 31 March 2009

Sexual dimorphism in body fat distribution and risk for cardiovascular diseases

scientific article published on 23 April 2009

Sexually dimorphic brain fatty acid composition in low and high fat diet-fed mice

scientific article published on 30 June 2016

Sexually dimorphic role of G protein-coupled estrogen receptor (GPER) in modulating energy homeostasis

scientific article

Shift in Kiss1 cell activity requires estrogen receptor α.

scientific article

Signaling through the ghrelin receptor modulates hippocampal function and meal anticipation in mice ⬇️

scientific article published on October 29, 2010

Silencing of estrogen receptor alpha in the ventromedial nucleus of hypothalamus leads to metabolic syndrome.

scholarly article

Small-molecule melanin-concentrating hormone-1 receptor antagonists require brain penetration for inhibition of food intake and reduction in body weight.

scientific article

Strategies to Counter Weight Loss-Induced Reductions in Metabolic Rate

scientific article published on 01 July 2019

Syndecan-3 modulates food intake by interacting with the melanocortin/AgRP pathway

scientific article

Tetrahydroindenoindole inhibits the progression of diabetes in mice

scientific article published on 07 September 2008

The ERα-PI3K Cascade in Proopiomelanocortin Progenitor Neurons Regulates Feeding and Glucose Balance in Female Mice.

scientific article

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

The Role of Estrogens in Control of Energy Balance and Glucose Homeostasis ⬇️

scientific article published on March 4, 2013

The catabolic action of insulin in the brain is mediated by melanocortins.

scientific article published in October 2002

The critical role of the melanocortin system in the control of energy balance

scientific article published on January 2004

The effects of 17 alpha-estradiol to inhibit inflammation in vitro.

scientific article published on 6 September 2017

The effects of oestrogens and their receptors on cardiometabolic health

scientific article

The impact of sex and sex hormones on cell function

scientific article published on 2 November 2017

The implications of vitamin D deficiency on COVID-19 for at-risk populations

scientific article published on 25 September 2020

The melanocortin antagonist AgRP (83-132) increases appetitive responding for a fat, but not a carbohydrate, reinforcer.

scientific article published on 23 December 2007

The physiology of obesity

scientific article published on 01 December 2004

The regulation of alcohol intake by melanin-concentrating hormone in rats

scientific journal article

The role of estrogens in the adipose tissue milieu

scientific article published on 23 December 2019

The role of hypothalamic estrogen receptors in metabolic regulation

scientific article

The role of previous exposure in the appetitive and consummatory effects of orexigenic neuropeptides

scientific article

The role of syndecans in the regulation of body weight and synaptic plasticity

scientific article published on 30 June 2007

The roles of leptin receptors on POMC neurons in the regulation of sex-specific energy homeostasis

scientific article published on March 2010

The sexual dimorphism of obesity

scientific article

The sexually dimorphic role of adipose and adipocyte estrogen receptors in modulating adipose tissue expansion, inflammation, and fibrosis

scientific article published on 04 June 2013

Thiazide-Associated Hyponatremia: A Major Dilemma Affecting Treatment

scientific article published on 19 April 2017

Transwomen and the Metabolic Syndrome: Is Orchiectomy Protective?

scientific article published in August 2016

Treatment of Abnormalities of Potassium Homeostasis in CKD.

scientific article published in September 2017

Ventromedial hypothalamic glucose sensing and glucose homeostasis vary throughout the estrous cycle

scientific article published on 22 September 2016

Voluntary consumption of ethyl oleate reduces food intake and body weight in rats.

scientific article

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