List of works - Yvo Smulders

18F-fluorodeoxyglucose positron emission tomography in elderly patients with an elevated erythrocyte sedimentation rate of unknown origin

scientific article

2016 European Guidelines on cardiovascular disease prevention in clinical practice

scientific article published in September 2016

2016 European Guidelines on cardiovascular disease prevention in clinical practice

scientific article published on 27 June 2016

2016 European Guidelines on cardiovascular disease prevention in clinical practice

scientific article published in October 2016

2016 European Guidelines on cardiovascular disease prevention in clinical practice: The Sixth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by repres

scientific article published on 23 May 2016

Acute angiotensin II receptor blockade improves insulin-induced microvascular function in hypertensive individuals

scientific article published on 14 April 2011

Angiotensin II enhances insulin-stimulated whole-body glucose disposal but impairs insulin-induced capillary recruitment in healthy volunteers

scientific article published on 25 May 2010

Bariatric surgery as a novel treatment for type 2 diabetes mellitus: a systematic review

scientific article published on June 2011

Body mass index is related to microvascular vasomotion, this is partly explained by adiponectin

scientific article

Cardiovascular risk management in patients with active ankylosing spondylitis: a detailed evaluation

scientific article

Carotid Intima Media Thickness in Rheumatoid Arthritis as Compared to Control Subjects: A Meta-Analysis ⬇️

scientific article published on April 1, 2011

Combined Intravital Microscopy and Contrast-enhanced Ultrasonography of the Mouse Hindlimb to Study Insulin-induced Vasodilation and Muscle Perfusion.

scientific article

Dihydrofolate reductase deficiency due to a homozygous DHFR mutation causes megaloblastic anemia and cerebral folate deficiency leading to severe neurologic disease

scientific article

Effect of B vitamin supplementation on plasma homocysteine levels in celiac disease

scientific article published on February 2009

Effect of vitamin B12 and folic acid supplementation on biomarkers of endothelial function and inflammation among elderly individuals with hyperhomocysteinemia

scientific article published on 15 January 2016

Effects of 2-year vitamin B12 and folic acid supplementation in hyperhomocysteinemic elderly on arterial stiffness and cardiovascular outcomes within the B-PROOF trial

scientific article published on September 2015

Emotional exhaustion and burnout among medical professors; a nationwide survey

scientific article

Endothelial dysfunction in (pre)diabetes: characteristics, causative mechanisms and pathogenic role in type 2 diabetes

scientific article published on March 2013

Folate metabolism and cardiovascular disease

scientific article

Frequent mutation in the ABCC6 gene (R1141X) is associated with a strong increase in the prevalence of coronary artery disease

scientific article (publication date: 13 August 2002)

Guía ESC 2016 sobre prevención de la enfermedad cardiovascular en la práctica clínica

Homocysteine level is associated with aortic stiffness in elderly

scientific article published on 01 May 2013

Homocysteine, B-vitamins, and the risk of cardiovascular disease

scientific article

How Much Overtesting Is Needed to Safely Exclude a Diagnosis? A Different Perspective on Triage Testing Using Bayes' Theorem

scientific article

Identification and characterization of an inborn error of metabolism caused by dihydrofolate reductase deficiency

scientific article

In vivo stable isotope measurements of methyl metabolism: applications in pathophysiology and interventions.

scientific article

Independent associations of glucose status and arterial stiffness with left ventricular diastolic dysfunction: an 8-year follow-up of the Hoorn Study

scientific article

Insulin Sensitivity Determines Effects of Insulin and Meal Ingestion on Systemic Vascular Resistance in Healthy Subjects

scientific article published on 30 November 2015

Insulin-induced changes in skeletal muscle microvascular perfusion are dependent upon perivascular adipose tissue in women

scientific article

Life-threatening complications of hormonal contraceptives: a case history

scientific article published on 20 May 2013

Meal-related increases in microvascular vasomotion are impaired in obese individuals: a potential mechanism in the pathogenesis of obesity-related insulin resistance

scientific article

Microvascular dysfunction: a potential mechanism in the pathogenesis of obesity-associated insulin resistance and hypertension.

scientific article published on January 2012

Microvascular function has no menstrual-cycle-dependent variation in healthy ovulatory women

scientific article

Microvascular function is preserved in newly diagnosed rheumatoid arthritis and low systemic inflammatory activity

scientific article

Moderate hyperoxic versus near-physiological oxygen targets during and after coronary artery bypass surgery: a randomised controlled trial.

scientific article published on 10 March 2016

New cardiovascular risk determinants do exist and are clinically useful

scientific article published on February 2008

No effect of epoprostenol on right ventricular diameter in patients with acute pulmonary embolism: a randomized controlled trial

scientific article

No effect of folic acid supplementation on global DNA methylation in men and women with moderately elevated homocysteine

scientific article (publication date: 2011)

Non-linear associations between serum 25-OH vitamin D and indices of arterial stiffness and arteriosclerosis in an older population.

scientific article published on 19 July 2014

Obese but not normal-weight women with polycystic ovary syndrome are characterized by metabolic and microvascular insulin resistance

scientific article

Obesity is associated with impaired endothelial function in the postprandial state

scientific article

Oscillometry and applanation tonometry measurements in older individuals with elevated levels of arterial stiffness.

scientific article published in December 2013

Overview of homocysteine and folate metabolism. With special references to cardiovascular disease and neural tube defects.

scientific article

Perivascular adipose tissue and its role in type 2 diabetes and cardiovascular disease

scientific article

Perivascular adipose tissue control of insulin-induced vasoreactivity in muscle is impaired in db/db mice

scientific article published on 9 October 2012

Personality Traits Are Associated with Research Misbehavior in Dutch Scientists: A Cross-Sectional Study

scientific article

Plasma folate levels are associated with the lipoprotein profile: a retrospective database analysis

scientific article

Premature aging of the microcirculation in patients with advanced chronic kidney disease

scientific article

Protein arginine methylation is more prone to inhibition by S-adenosylhomocysteine than DNA methylation in vascular endothelial cells

scientific article

Publication pressure and burn out among Dutch medical professors: a nationwide survey

scientific article

Pulmonary Arterial Hypertension in Systemic Sclerosis Is Associated with Profound Impairment of Microvascular Endothelium-dependent Vasodilatation ⬇️

scientific article published on December 15, 2011

Rapid, accurate, and on-site detection of C. difficile in stool samples.

scientific article

Reduction in skin microvascular density and changes in vessel morphology in patients treated with sunitinib

scientific article

Regulation of vascular function and insulin sensitivity by adipose tissue: focus on perivascular adipose tissue

scientific article published on June 2007

Signs of accelerated preclinical atherosclerosis in patients with ankylosing spondylitis

scientific article published in December 2009

Stwl modifies chromatin compaction and is required to maintain DNA integrity in the presence of perturbed DNA replication.

scientific article published on 03 December 2008

The effect of anti-TNF treatment on body composition and insulin resistance in patients with rheumatoid arthritis

scientific article published on 10 August 2020

The homocysteine controversy

scientific article

The methylenetetrahydrofolate reductase (MTHFR) variant c.677C>T (A222V) influences overall survival of patients with glioblastoma multiforme

scientific article published on 22 May 2008

The potential harm of oxygen therapy in medical emergencies

scientific article published on 18 April 2013

The relationship of body fatness and body fat distribution with microvascular recruitment: The Amsterdam Growth and Health Longitudinal Study

scientific article published in April 2012

Wytyczne ESC dotyczące prewencji chorób układu sercowo-naczyniowego w praktyce klinicznej w 2016 roku

scientific article published on 9 September 2016

[2016 European guidelines on cardiovascular disease prevention in clinical practice. The Sixth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by repre

scientific article published in July 2017

List of works by Yvo Smulders

18F-fluorodeoxyglucose positron emission tomography in elderly patients with an elevated erythrocyte sedimentation rate of unknown origin

2016 European Guidelines on cardiovascular disease prevention in clinical practice

2016 European Guidelines on cardiovascular disease prevention in clinical practice

2016 European Guidelines on cardiovascular disease prevention in clinical practice

2016 European Guidelines on cardiovascular disease prevention in clinical practice: The Sixth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by repres

Acute angiotensin II receptor blockade improves insulin-induced microvascular function in hypertensive individuals

Angiotensin II enhances insulin-stimulated whole-body glucose disposal but impairs insulin-induced capillary recruitment in healthy volunteers

Bariatric surgery as a novel treatment for type 2 diabetes mellitus: a systematic review

Body mass index is related to microvascular vasomotion, this is partly explained by adiponectin

Cardiovascular risk management in patients with active ankylosing spondylitis: a detailed evaluation

Carotid Intima Media Thickness in Rheumatoid Arthritis as Compared to Control Subjects: A Meta-Analysis ⬇️

Combined Intravital Microscopy and Contrast-enhanced Ultrasonography of the Mouse Hindlimb to Study Insulin-induced Vasodilation and Muscle Perfusion.

Dihydrofolate reductase deficiency due to a homozygous DHFR mutation causes megaloblastic anemia and cerebral folate deficiency leading to severe neurologic disease

Effect of B vitamin supplementation on plasma homocysteine levels in celiac disease

Effect of vitamin B12 and folic acid supplementation on biomarkers of endothelial function and inflammation among elderly individuals with hyperhomocysteinemia

Effects of 2-year vitamin B12 and folic acid supplementation in hyperhomocysteinemic elderly on arterial stiffness and cardiovascular outcomes within the B-PROOF trial

Emotional exhaustion and burnout among medical professors; a nationwide survey

Endothelial dysfunction in (pre)diabetes: characteristics, causative mechanisms and pathogenic role in type 2 diabetes

Folate metabolism and cardiovascular disease

Frequent mutation in the ABCC6 gene (R1141X) is associated with a strong increase in the prevalence of coronary artery disease

Guía ESC 2016 sobre prevención de la enfermedad cardiovascular en la práctica clínica

Homocysteine level is associated with aortic stiffness in elderly

Homocysteine, B-vitamins, and the risk of cardiovascular disease

How Much Overtesting Is Needed to Safely Exclude a Diagnosis? A Different Perspective on Triage Testing Using Bayes' Theorem

Identification and characterization of an inborn error of metabolism caused by dihydrofolate reductase deficiency

In vivo stable isotope measurements of methyl metabolism: applications in pathophysiology and interventions.

Independent associations of glucose status and arterial stiffness with left ventricular diastolic dysfunction: an 8-year follow-up of the Hoorn Study

Insulin Sensitivity Determines Effects of Insulin and Meal Ingestion on Systemic Vascular Resistance in Healthy Subjects

Insulin-induced changes in skeletal muscle microvascular perfusion are dependent upon perivascular adipose tissue in women

Life-threatening complications of hormonal contraceptives: a case history

Meal-related increases in microvascular vasomotion are impaired in obese individuals: a potential mechanism in the pathogenesis of obesity-related insulin resistance

Microvascular dysfunction: a potential mechanism in the pathogenesis of obesity-associated insulin resistance and hypertension.

Microvascular function has no menstrual-cycle-dependent variation in healthy ovulatory women

Microvascular function is preserved in newly diagnosed rheumatoid arthritis and low systemic inflammatory activity

Moderate hyperoxic versus near-physiological oxygen targets during and after coronary artery bypass surgery: a randomised controlled trial.

New cardiovascular risk determinants do exist and are clinically useful

No effect of epoprostenol on right ventricular diameter in patients with acute pulmonary embolism: a randomized controlled trial

No effect of folic acid supplementation on global DNA methylation in men and women with moderately elevated homocysteine

Non-linear associations between serum 25-OH vitamin D and indices of arterial stiffness and arteriosclerosis in an older population.

Obese but not normal-weight women with polycystic ovary syndrome are characterized by metabolic and microvascular insulin resistance

Obesity is associated with impaired endothelial function in the postprandial state

Oscillometry and applanation tonometry measurements in older individuals with elevated levels of arterial stiffness.

Overview of homocysteine and folate metabolism. With special references to cardiovascular disease and neural tube defects.

Perivascular adipose tissue and its role in type 2 diabetes and cardiovascular disease

Perivascular adipose tissue control of insulin-induced vasoreactivity in muscle is impaired in db/db mice

Personality Traits Are Associated with Research Misbehavior in Dutch Scientists: A Cross-Sectional Study

Plasma folate levels are associated with the lipoprotein profile: a retrospective database analysis

Premature aging of the microcirculation in patients with advanced chronic kidney disease

Protein arginine methylation is more prone to inhibition by S-adenosylhomocysteine than DNA methylation in vascular endothelial cells

Publication pressure and burn out among Dutch medical professors: a nationwide survey

Pulmonary Arterial Hypertension in Systemic Sclerosis Is Associated with Profound Impairment of Microvascular Endothelium-dependent Vasodilatation ⬇️

Rapid, accurate, and on-site detection of C. difficile in stool samples.

Reduction in skin microvascular density and changes in vessel morphology in patients treated with sunitinib

Regulation of vascular function and insulin sensitivity by adipose tissue: focus on perivascular adipose tissue

Signs of accelerated preclinical atherosclerosis in patients with ankylosing spondylitis

Stwl modifies chromatin compaction and is required to maintain DNA integrity in the presence of perturbed DNA replication.

The effect of anti-TNF treatment on body composition and insulin resistance in patients with rheumatoid arthritis

The homocysteine controversy

The methylenetetrahydrofolate reductase (MTHFR) variant c.677C>T (A222V) influences overall survival of patients with glioblastoma multiforme

The potential harm of oxygen therapy in medical emergencies

The relationship of body fatness and body fat distribution with microvascular recruitment: The Amsterdam Growth and Health Longitudinal Study

Wytyczne ESC dotyczące prewencji chorób układu sercowo-naczyniowego w praktyce klinicznej w 2016 roku

[2016 European guidelines on cardiovascular disease prevention in clinical practice. The Sixth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by repre