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List of works by Sergej Konoplev

A phase I first-in-human trial of bardoxolone methyl in patients with advanced solid tumors and lymphomas

scientific article

Antileukemia activity of the novel peptidic CXCR4 antagonist LY2510924 as monotherapy and in combination with chemotherapy

scientific article published in June 2015

Autoimmune cytopenias in patients with chronic lymphocytic leukemia treated with ibrutinib

scientific article published on 24 March 2016

CD123 expression patterns and selective targeting with a CD123-specific antibody-drug conjugate (IMGN632) in acute lymphoblastic leukemia

scholarly article by Evgeniya Angelova et al published 25 October 2018 in Haematologica

CD33 is frequently expressed in cases of myelodysplastic syndrome and chronic myelomonocytic leukemia with elevated blast count

scientific article published on 4 January 2016

CXC chemokine receptor 4 expression, CXC chemokine receptor 4 activation, and wild-type nucleophosmin are independently associated with unfavorable prognosis in patients with acute myeloid leukemia

scientific article

CXCR4 up-regulation by imatinib induces chronic myelogenous leukemia (CML) cell migration to bone marrow stroma and promotes survival of quiescent CML cells

scientific article published on January 2008

Clonal evolution in patients with chronic lymphocytic leukaemia developing resistance to BTK inhibition

scientific article published on 20 May 2016

Co-occurrence of CRLF2-rearranged and Ph+ acute lymphoblastic leukemia: a report of four patients

scientific article published on 31 August 2017

Concomitant inhibition of DNA methyltransferase and BCL-2 protein function synergistically induce mitochondrial apoptosis in acute myelogenous leukemia cells

scientific article published on 15 August 2012

Connective tissue growth factor regulates adipocyte differentiation of mesenchymal stromal cells and facilitates leukemia bone marrow engraftment

scientific article published on 05 June 2013

Cytoplasmic localization of nucleophosmin in bone marrow blasts of acute myeloid leukemia patients is not completely concordant with NPM1 mutation and is not predictive of prognosis

scientific article

Epstein-Barr virus-induced CD30-positive diffuse large B-cell lymphoma in a patient with mixed-phenotypic leukemia treated with clofarabine

scientific article published on 14 December 2012

HCVAD plus imatinib or dasatinib in lymphoid blastic phase chronic myeloid leukemia

scientific article published on 22 October 2013

High serum thymidine kinase 1 level predicts poorer survival in patients with chronic lymphocytic leukemia

scientific article published on September 2010

Human extramedullary bone marrow in mice: a novel in vivo model of genetically controlled hematopoietic microenvironment

scientific article

Hypocellular acute myeloid leukemia in adults: analysis of the clinical outcome of 123 patients ⬇️

scientific article published on November 4, 2011

Hypoxia-Activated Prodrug TH-302 Targets Hypoxic Bone Marrow Niches in Preclinical Leukemia Models

scientific article published on 24 November 2015

Malignancy-associated hemophagocytic lymphohistiocytosis in adults: Relation to hemophagocytosis, characteristics, and outcomes

scientific article published on 31 May 2016

Molecular characterization of de novo Philadelphia chromosome-positive acute myeloid leukemia

scientific article published on 09 July 2012

PPARgamma-active triterpenoid CDDO enhances ATRA-induced differentiation in APL.

scientific article published on 4 September 2007

Persistence of minimal residual disease assessed by multiparameter flow cytometry is highly prognostic in younger patients with acute myeloid leukemia

scientific article published on 22 September 2016

Ph-like acute lymphoblastic leukemia: a high-risk subtype in adults

scientific article published on 5 December 2016

Phase I study of evofosfamide, an investigational hypoxia-activated prodrug, in patients with advanced leukemia

scientific article published on 11 May 2016

Phase I/II study of the hypoxia-activated prodrug PR104 in refractory/relapsed acute myeloid leukemia and acute lymphoblastic leukemia

scientific article

Phosphorylated CXCR4 is associated with poor survival in adults with B-acute lymphoblastic leukemia

scientific article published on 31 March 2011

Pronounced hypoxia in models of murine and human leukemia: high efficacy of hypoxia-activated prodrug PR-104

scientific article (publication date: 2011)

Regulation of HIF-1α signaling and chemoresistance in acute lymphocytic leukemia under hypoxic conditions of the bone marrow microenvironment

scientific article

Relapsed Refractory BRAF-Negative, IGHV4-34-Positive Variant of Hairy Cell Leukemia: A Distinct Entity?

scientific article

Secondary Philadelphia chromosome acquired during therapy of acute leukemia and myelodysplastic syndrome

scientific article published on 14 February 2018

Significance of recurrence of minimal residual disease detected by multi-parameter flow cytometry in patients with acute lymphoblastic leukemia in morphological remission

scientific article published on 4 January 2017

Synchronous del5q myelodysplastic syndrome (del5qMDS) and adult B-cell acute lymphoblastic leukemia (B-ALL) with TET2 and TP53 mutations

scientific article published on 6 October 2015

TET2 mutations, myelodysplastic features, and a distinct immunoprofile characterize blastic plasmacytoid dendritic cell neoplasm in the bone marrow

scientific article published on 30 September 2013

Targeting the leukemia microenvironment by CXCR4 inhibition overcomes resistance to kinase inhibitors and chemotherapy in AML.

scientific article published on 27 October 2008

The synthetic triterpenoid, CDDO, suppresses alloreactive T cell responses and reduces murine early acute graft-versus-host disease mortality

scientific article

Unusual Case of Anaplastic Large Cell Lymphoma Presenting as a Breast Mass in a Patient with no History of Breast Implants

scientific article published on 23 July 2020

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