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List of works by Harald von Boehmer

A critical role for the cytoplasmic tail of pTα in T lymphocyte development

article

A multistep adhesion cascade for lymphoid progenitor cell homing to the thymus

scholarly article

Activation of beta -catenin signaling in differentiated mammary secretory cells induces transdifferentiation into epidermis and squamous metaplasias.

scientific article

Alphabeta versus gammadelta lineage choice at the first TCR-controlled checkpoint

scientific article

Analysis and expression of a cloned pre-T cell receptor gene. Science. 1994. 266: 1208-1212.

scientific article published in May 2009

Antigen-Specific Induction of Regulatory T Cells In Vivo and In Vitro ⬇️

scientific article published on January 1, 2011

Antigen-specific FoxP3-transduced T-cells can control established type 1 diabetes

scientific article

BCL-2 and BCL-XL restrict lineage choice during hematopoietic differentiation

scientific article published on 28 April 2003

Beta-catenin stabilization stalls the transition from double-positive to single-positive stage and predisposes thymocytes to malignant transformation

scientific article published on 22 February 2007

Central tolerance: essential for preventing autoimmune disease?

scientific article published on 01 September 2009

Characterization of T cell differentiation in the murine gut.

scientific article

Checkpoints in lymphocyte development and autoimmune disease

scientific article published on 17 December 2009

Combined expression of pTalpha and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis

scientific article

Commitment and developmental potential of extrathymic and intrathymic T cell precursors: plenty to choose from

scientific article published on June 2007

Constitutive endocytosis and degradation of the pre-T cell receptor.

scientific article

Cyclin C is a haploinsufficient tumour suppressor

scientific article

DNA methylation controls Foxp3 gene expression

scientific article

De novo production of antigen-specific suppressor cells in vivo.

scientific article

Differential synergy of Notch and T cell receptor signaling determines alphabeta versus gammadelta lineage fate.

scientific article

Direct presentation of antigen by lymph node stromal cells protects against CD8 T-cell-mediated intestinal autoimmunity.

scientific article

Down-regulation of diabetogenic CD4+ T cells by a soluble dimeric peptide-MHC class II chimera

scientific article published on 25 February 2002

Dynamics of suppressor T cells: in vivo veritas

scientific article published on September 2003

Effective destruction of Fas-deficient insulin-producing beta cells in type 1 diabetes

scientific article published on October 2003

Efficient thymic immigration of B220+ lymphoid-restricted bone marrow cells with T precursor potential

scientific article published on 17 August 2003

Enhancement of antigen-specific Treg vaccination in vivo

scientific article

Erratum: Crucial role of the pre-T-cell receptor α gene in development of αβ but not γ§ T cells

scientific article published in Nature

Extra-thymically induced regulatory T cells: do they have potential in disease prevention?

scientific article

Extrathymic generation of regulatory T cells--chances and challenges for prevention of autoimmune disease

scientific article

Foxp3 occupancy and regulation of key target genes during T-cell stimulation

scientific article

Genomic definition of multiple ex vivo regulatory T cell subphenotypes

scientific article

Identification of a T lineage-committed progenitor in adult blood.

scientific article published on 11 January 2007

Immunological tolerance

scholarly article by Harald von Boehmer & Herman Waldmann published 2010 in Frontiers in Immunology

Immunology. Thoracic thymus, exclusive no longer

scientific article published on 01 April 2006

In vivo dynamics of antigen-specific regulatory T cells not predicted from behavior in vitro

scientific article

In vivo instruction of suppressor commitment in naive T cells

scientific article

Inducing and expanding regulatory T cell populations by foreign antigen

scientific article published on 23 October 2005

Induction of antigen-specific regulatory T cells in wild-type mice: visualization and targets of suppression

scholarly article

Instruction of Treg commitment in peripheral T cells is suited to reverse autoimmunity

scientific article

Interconnecting molecular pathways in the pathogenesis and drug sensitivity of T-cell acute lymphoblastic leukemia

scientific article

Kruppel-like factor KLF10 targets transforming growth factor-beta1 to regulate CD4(+)CD25(-) T cells and T regulatory cells

scientific article published on 14 July 2009

Lineage diversion of T cell receptor transgenic thymocytes revealed by lineage fate mapping.

scientific article

Lymphocyte development: overview

scientific article published on April 2008

Making regulatory T cells with defined antigen specificity: role in autoimmunity and cancer

scientific article (publication date: August 2006)

Mechanisms of self-nonself discrimination and possible clinical relevance

scientific article

Mechanisms of suppression by suppressor T cells

scientific article

Multiple extrathymic precursors contribute to T-cell development with different kinetics

scientific article

Negative selection of the T-cell repertoire: where and when does it occur?

scientific article published in February 2006

Negative selection, not receptor editing, is a physiological response of autoreactive thymocytes.

scientific article published on 26 August 2013

Neuropilin-1: a surface marker of regulatory T cells

scientific article published on March 2004

Normal incidence of diabetes in NOD mice tolerant to glutamic acid decarboxylase

scientific article

Notch 1 activation in the molecular pathogenesis of T-cell acute lymphoblastic leukaemia

scientific article

Notch 1 keeps pro-T cells on track

scientific article published on 01 January 2009

Notch Signaling in T-Cell Development and T-ALL

scientific article

Notch in lymphopoiesis and T cell polarization

scientific article published on 01 July 2005

Notch1-dependent lymphomagenesis is assisted by but does not essentially require pre-TCR signaling

scientific article published on 28 February 2006

On the brink of becoming a T cell.

scientific article

On the edge of autoimmunity: T-cell stimulation by steady-state dendritic cells prevents autoimmune diabetes

scientific article published in December 2005

Oncogenesis of T-ALL and nonmalignant consequences of overexpressing intracellular NOTCH1

scientific article published on 3 November 2008

Oral tolerance: is it all retinoic acid?

scientific article published on 9 July 2007

Origin of regulatory T cells with known specificity for antigen

scientific article published on 01 July 2002

PI3 kinase signalling blocks Foxp3 expression by sequestering Foxo factors

scientific article

PLZF Controls the Expression of a Limited Number of Genes Essential for NKT Cell Function ⬇️

scientific article published on December 21, 2012

Peripherally induced Treg: mode, stability, and role in specific tolerance.

scientific article published on 8 October 2008

Phenotypic plasticity of T cell progenitors upon exposure to Notch ligands

scientific article

Positive and negative selection in Basel

scientific article published on 01 June 2008

Positive selection by the pre-TCR yields mature CD8+ T cells

scientific article published in November 2002

Pre-TCR-triggered ERK signalling-dependent downregulation of E2A activity in Notch3-induced T-cell lymphoma ⬇️

scientific article published on October 17, 2003

Pre-TCRalpha and TCRalpha are not interchangeable partners of TCRbeta during T lymphocyte development

scientific article

Prevention of type 1 diabetes in mice by tolerogenic vaccination with a strong agonist insulin mimetope

scientific article

Projection of an immunological self shadow within the thymus by the aire protein

scientific article (publication date: 15 November 2002)

Promoting tolerance to proteolipid protein-induced experimental autoimmune encephalomyelitis through targeting dendritic cells ⬇️

scientific article published on September 20, 2010

Recessive tolerance to preproinsulin 2 reduces but does not abolish type 1 diabetes

scientific article published on 19 September 2004

Regulatory T cells and antigen-specific tolerance

scientific article published on January 2008

Regulatory T cells reversibly suppress cytotoxic T cell function independent of effector differentiation

scientific article published on July 2006

Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-beta signals in vivo

scientific article

Reply to "Tolerogenic insulin peptide therapy precipitates type 1 diabetes".

scientific article

Repression of tumor suppressor miR-451 is essential for NOTCH1-induced oncogenesis in T-ALL ⬇️

scientific article published on April 4, 2011

Requirement for cyclin D3 in lymphocyte development and T cell leukemias

scientific journal article

Retinoic acid can enhance conversion of naive into regulatory T cells independently of secreted cytokines

scientific article published on 8 September 2009

Selection of the T-cell repertoire: receptor-controlled checkpoints in T-cell development

scientific article published in January 2004

Shaping the T cell repertoire

scientific article

Shaping the T cell repertoire

scientific article published on 01 January 2006

Smad3 binding to the foxp3 enhancer is dispensable for the development of regulatory T cells with the exception of the gut.

scientific article

Stabilization of beta-catenin induces lesions reminiscent of prostatic intraepithelial neoplasia, but terminal squamous transdifferentiation of other secretory epithelia

scientific article

Stage-specific and differential notch dependency at the alphabeta and gammadelta T lineage bifurcation

scientific article published on 29 June 2006

T cell receptor-instructed alphabeta versus gammadelta lineage commitment revealed by single-cell analysis.

scientific article published on 28 April 2008

TCR and Notch synergize in alphabeta versus gammadelta lineage choice

scientific article published on 29 January 2007

TCR-inducible PLZF transcription factor required for innate phenotype of a subset of gammadelta T cells with restricted TCR diversity

scientific article

The BCL2A1 gene as a pre-T cell receptor-induced regulator of thymocyte survival

scientific journal article

The E delta enhancer controls the generation of CD4- CD8- alphabetaTCR-expressing T cells that can give rise to different lineages of alphabeta T cells

scientific article

The Requirement for Cyclin D Function in Tumor Maintenance ⬇️

scientific article published on October 16, 2012

The TAL1 complex targets the FBXW7 tumor suppressor by activating miR-223 in human T cell acute lymphoblastic leukemia

scientific article published on 15 July 2013

The impact of CD4+CD25+ Treg on tumor specific CD8+ T cell cytotoxicity and cancer

scientific article

The manipulation of immunity. Conference on from allergy to cancer: new perspectives for therapeutic vaccination

scientific article

The transcriptional landscape of αβ T cell differentiation

scientific article

Therapeutic opportunities for manipulating TReg cells in autoimmunity and cancer ⬇️

scientific article published on January 1, 2013

Thymic selection revisited: how essential is it?

scientific article

Thymocyte selection: chemokine signaling is not only about the destination

scientific article published in April 2010

Tracing lymphopoiesis with the aid of a pTα-controlled reporter gene

article

Transgenically induced GAD tolerance curtails the development of early beta-cell autoreactivities but causes the subsequent development of supernormal autoreactivities to other beta-cell antigens

scientific article published on 09 September 2009

Type 1 diabetes: focus on prevention

scientific article published on 01 August 2004

Unique features of the pre-T-cell receptor alpha-chain: not just a surrogate

scientific article

Visualizing the course of antigen-specific CD8 and CD4 T cell responses to a growing tumor

scientific article

What turns on Foxp3?

scientific article published on 01 February 2008

c-Myc mediates pre-TCR-induced proliferation but not developmental progression

scientific article published on 20 June 2006

gammadeltaTCR ligands and lineage commitment

scientific article

p16INK4A tumor suppressor gene expression and CD3epsilon deficiency but not pre-TCR deficiency inhibit TAL1-linked T-lineage leukemogenesis

scientific article

αβ versus γδ fate choice: counting the T-cell lineages at the branch point.

scientific article

β-Selection-Induced Proliferation Is Required for αβ T Cell Differentiation ⬇️

scientific article published on November 16, 2012

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