Search filters

List of works by William G Blum

A novel regimen for relapsed/refractory adult acute myeloid leukemia using a KMT2A partial tandem duplication targeted therapy: results of phase 1 study NCI 8485.

scientific article published on 22 March 2018

A phase I biological study of MG98, an oligodeoxynucleotide antisense to DNA methyltransferase 1, in patients with high-risk myelodysplasia and acute myeloid leukemia

scientific article

Adult de novo acute myeloid leukemia with t(6;11)(q27;q23): results from Cancer and Leukemia Group B Study 8461 and review of the literature

scientific article published in September 2004

Bortezomib induces DNA hypomethylation and silenced gene transcription by interfering with Sp1/NF-kappaB-dependent DNA methyltransferase activity in acute myeloid leukemia

scientific article

Characterization of in vitro and in vivo hypomethylating effects of decitabine in acute myeloid leukemia by a rapid, specific and sensitive LC-MS/MS method

scientific article published on 30 January 2007

Clinical and pharmacodynamic activity of bortezomib and decitabine in acute myeloid leukemia ⬇️

scientific article published on May 7, 2012

Clinical response and miR-29b predictive significance in older AML patients treated with a 10-day schedule of decitabine

scientific article

Dose escalation of lenalidomide in relapsed or refractory acute leukemias

scientific article

Expression and prognostic impact of lncRNAs in acute myeloid leukemia

scientific article

Genome-wide methylation profiling in decitabine-treated patients with acute myeloid leukemia

scientific article

High disease burden is associated with poor outcomes for patients with acute myeloid leukemia not in remission who undergo unrelated donor cell transplantation

scientific article

Hyperglycemia in patients with acute myeloid leukemia is associated with increased hospital mortality

scientific article published in July 2007

Improved nonrelapse mortality and infection rate with lower dose of antithymocyte globulin in patients undergoing reduced-intensity conditioning allogeneic transplantation for hematologic malignancies

scientific article published on September 2009

In Vivo Quantification of Active Decitabine-Triphosphate Metabolite: A Novel Pharmacoanalytical Endpoint for Optimization of Hypomethylating Therapy in Acute Myeloid Leukemia ⬇️

scientific article published on November 22, 2012

Lenalidomide down-regulates the CD20 antigen and antagonizes direct and antibody-dependent cellular cytotoxicity of rituximab on primary chronic lymphocytic leukemia cells

scientific article published on 04 September 2008

Lenalidomide treatment promotes CD154 expression on CLL cells and enhances production of antibodies by normal B cells through a PI3-kinase-dependent pathway

scientific article

Lenalidomide-mediated enhanced translation of C/EBPα-p30 protein up-regulates expression of the antileukemic microRNA-181a in acute myeloid leukemia

scientific article published on 25 October 2012

MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1.

scientific article published on 11 February 2009

MicroRNA-29b mediates altered innate immune development in acute leukemia

scientific article published on 24 October 2016

PP2A-activating drugs selectively eradicate TKI-resistant chronic myeloid leukemic stem cells

scientific article published on 03 September 2013

Persistence of DNMT3A R882 mutations during remission does not adversely affect outcomes of patients with acute myeloid leukaemia

scientific article published on August 2016

Pharmacokinetics and dose escalation of the heat shock protein inhibitor 17-allyamino-17-demethoxygeldanamycin in combination with bortezomib in relapsed or refractory acute myeloid leukemia

scientific article published on 24 January 2013

Phase I clinical and pharmacokinetic study of a novel schedule of flavopiridol in relapsed or refractory acute leukemias

scientific article

Phase I study of GTI-2040, a ribonucleotide reductase antisense, with high dose cytarabine in patients with relapsed/refractory acute myeloid leukemia

scientific article

Phase I study of GTI-2040, an antisense to ribonucleotide reductase, in combination with high-dose cytarabine in patients with acute myeloid leukemia

scientific article

Phase I study of azacitidine and bortezomib in adults with relapsed or refractory acute myeloid leukemia ⬇️

scientific article published on 09 September 2013

Phase I study of decitabine alone or in combination with valproic acid in acute myeloid leukemia

scientific article

Phase I study of oblimersen sodium, an antisense to Bcl-2, in untreated older patients with acute myeloid leukemia: pharmacokinetics, pharmacodynamics, and clinical activity

scientific article published on 11 April 2005

Prognostic and biologic significance of long non-coding RNA profiling in younger adults with cytogenetically normal acute myeloid leukemia

scientific article published on 04 May 2017

SPARC promotes leukemic cell growth and predicts acute myeloid leukemia outcome

scientific article published on 03 March 2014

Single-agent lenalidomide induces complete remission of acute myeloid leukemia in patients with isolated trisomy 13.

scientific article

TET2 mutations improve the new European LeukemiaNet risk classification of acute myeloid leukemia: a Cancer and Leukemia Group B study

scientific article

Targeted delivery of microRNA-29b by transferrin-conjugated anionic lipopolyplex nanoparticles: a novel therapeutic strategy in acute myeloid leukemia

scientific article published on 14 March 2013

Treating acute myeloid leukemia in the modern era: A primer

scientific article published on 07 August 2020

inv(16)/t(16;16) acute myeloid leukemia with non-type A CBFB-MYH11 fusions associate with distinct clinical and genetic features and lack KIT mutations

scientific article published on 16 November 2012

Paulina is supported by:

About Paulina

Help