List of works - Koichi Goto

A Minimum Of 100 Tumor Cells in a Single Biopsy Sample Is Required to Assess Programmed Cell Death Ligand 1 Expression in Predicting Patient Response to Nivolumab Treatment in Nonsquamous Non-Small Cell Lung Carcinoma

scientific article published on 28 June 2019

A nationwide genomic screening project for small cell lung cancer in Japan (LC-SCRUM-Japan)

scientific article published on 01 October 2017

A nationwide genomic screening project for small cell lung cancer in Japan (LC-SCRUM-Japan)

A novel histopathological evaluation method predicting the outcome of non-small cell lung cancer treated by neoadjuvant therapy: the prognostic importance of the area of residual tumor

scientific article published in January 2010

Acute and Progressive Tracheal Stenosis after Proton Beam Therapy with Concurrent Chemotherapy for Non-Small Cell Lung Cancer

scientific article published on 21 April 2016

Aggressive tumor microenvironment of solid predominant lung adenocarcinoma subtype harboring with epidermal growth factor receptor mutations

scientific article published on 15 November 2015

Aldehyde dehydrogenase 1 expression in cancer cells could have prognostic value for patients with non-small cell lung cancer who are treated with neoadjuvant therapy: identification of prognostic microenvironmental factors after chemoradiation

scientific article published in December 2013

Amplification of EGFR Wild-Type Alleles in Non-Small Cell Lung Cancer Cells Confers Acquired Resistance to Mutation-Selective EGFR Tyrosine Kinase Inhibitors

scientific article published on 15 February 2017

Assessment of PD-L1 expression and oncogenic gene status in patients with small-cell lung cancer: Immuno-oncology biomarker study in LC-SCRUM-Japan

Association between GWAS-identified lung adenocarcinoma susceptibility loci and EGFR mutations in never-smoking Asian women, and comparison with findings from Western populations

scientific article published on 26 December 2016

Association between immune-related adverse events and efficacy of nivolumab in advanced non-small cell lung cancer

scientific article published on 01 October 2017

Association between the mutational smoking signature and the immune microenvironment in lung adenocarcinoma

scientific article published on 01 July 2020

Association of Serum Anti-GAD Antibody and HLA Haplotypes with Type 1 Diabetes Mellitus Triggered by Nivolumab in Patients with Non-Small Cell Lung Cancer

scientific article published on 23 December 2016

Association of variations in HLA class II and other loci with susceptibility to EGFR-mutated lung adenocarcinoma

scientific article published on 09 August 2016

Breast cancer in first-degree relatives and risk of lung cancer: assessment of the existence of gene sex interactions

scientific article published on 23 June 2007

Breast cancer resistance protein impacts clinical outcome in platinum-based chemotherapy for advanced non-small cell lung cancer

scientific article published in March 2004

CD200-positive cancer associated fibroblasts augment the sensitivity of Epidermal Growth Factor Receptor mutation-positive lung adenocarcinomas to EGFR Tyrosine kinase inhibitors

scientific article

Cancer cell invasion driven by extracellular matrix remodeling is dependent on the properties of cancer-associated fibroblasts

scientific article published on 15 September 2015

Changes in the tumor microenvironment during lymphatic metastasis of lung squamous cell carcinoma

scientific article published on 20 October 2016

Characterization of the immunophenotype of the tumor budding and its prognostic implications in squamous cell carcinoma of the lung ⬇️

scientific article published on December 6, 2011

Characterization of the tumor immune-microenvironment of lung adenocarcinoma associated with usual interstitial pneumonia

scientific article published on 06 November 2018

Clinical Impact of Gastric Acid-Suppressing Medication Use on the Efficacy of Erlotinib and Gefitinib in Patients With Advanced Non-Small-Cell Lung Cancer Harboring EGFR Mutations.

scientific article

Clinical features of squamous cell lung cancer with targetable gene alterations in a nationwide genomic screening network in Japan (LC-SCRUM-Japan)

Clinical features of unresectable high-grade lung neuroendocrine carcinoma diagnosed using biopsy specimens

scientific article published on 13 September 2011

Clinico-pathological and genomic features of NRAS- or HRAS-mutated non-small cell lung cancer (NSCLC) identified in large-scale genomic screening project (LC-SCRUM-Asia)

scientific article

Clinicopathological characteristics of EGFR mutated adenosquamous carcinoma of the lung.

scientific article

Collagen type I induces EGFR-TKI resistance in EGFR-mutated cancer cells via mTOR activation through Akt-independent pathway.

scientific article published on 27 April 2018

Combined effect of cabozantinib and gefitinib in crizotinib-resistant lung tumors harboring ROS1 fusions

Comparison of the expression levels of molecular markers among the peripheral area and central area of primary tumor and metastatic lymph node tumor in patients with squamous cell carcinoma of the lung

scientific article published on 09 January 2015

Contribution of nationwide genome screening in Japan (LC-SCRUM-Japan) to the development of precision medicine for non-small cell lung cancer

Contribution to the development of precision medicine and clinical utility of nationwide lung cancer genomic screening in Japan (LC-SCRUM-Japan)

Detectability of druggable gene fusions by amplicon-based next generation sequencing in LC-SCRUM-Japan

scientific article

Development of a nationwide genomic screening network for squamous cell lung cancer in Japan (LC-SCRUM-Japan)

Development of a nationwide genomic screening project (LC-SCRUM-Japan) for small cell lung cancer for precision medicine

scientific article

Development of nationwide genomic screening project (LC-SCRUM-Japan) contributing to the establishment of precision medicine in Japan

Docetaxel for platinum-refractory advanced thymic carcinoma

scientific article published on 02 April 2015

Dominant papillary subtype is a significant predictor of the response to gefitinib in adenocarcinoma of the lung

scientific article published in November 2004

Effect of food on the pharmacokinetics of TAS-102 and its efficacy and safety in patients with advanced solid tumors

scientific article published on 26 February 2016

Eg5 expression is closely correlated with the response of advanced non-small cell lung cancer to antimitotic agents combined with platinum chemotherapy.

scientific article

Emergence and Targeting of Acquired and Hereditary Resistance to Multikinase RET Inhibition in Patients With RET-Altered Cancer

scientific article published on 11 September 2019

Evaluation of variant frequency in SARS-CoV-2 infection-related genes utilizing lung cancer genomic database

scientific article published on 23 December 2020

Expression of breast cancer resistance protein is associated with a poor clinical outcome in patients with small-cell lung cancer.

scientific article published on 25 November 2008

Expression profiling of receptor tyrosine kinases in high-grade neuroendocrine carcinoma of the lung: a comparative analysis with adenocarcinoma and squamous cell carcinoma

scientific article

Factors influencing the concordance of histological subtype diagnosis from biopsy and resected specimens of lung adenocarcinoma

scientific article

Feasibility of transbronchial brushing cytology specimens for next generation sequencing in peripheral lung cancer

scientific article published on 30 October 2020

Fibroblast-led cancer cell invasion is activated by epithelial-mesenchymal transition through platelet-derived growth factor BB secretion of lung adenocarcinoma

scientific article

Genetic profiling and the response to RET inhibitors in RET fusion positive non-small cell lung cancer (NSCLC) identified by international genomic screening project (LC-SCRUM-Asia)

scientific article

Genetic profiling-based prognostic prediction of patients with advanced small-cell lung cancer in large scale analysis

scientific article published on 12 November 2018

Genomic Profiling of Large-Cell Neuroendocrine Carcinoma of the Lung

scientific article published on 9 August 2016

Identification of a lung adenocarcinoma cell line with CCDC6-RET fusion gene and the effect of RET inhibitors in vitro and in vivo

scientific article published on 12 May 2013

Identification of biological properties of intralymphatic tumor related to the development of lymph node metastasis in lung adenocarcinoma

scientific article

Identification of prognostic immunophenotypic features in cancer stromal cells of high-grade neuroendocrine carcinomas of the lung

scientific article published on 7 September 2013

Immuno-oncology biomarker study in a large cohort of LC-SCRUM-Japan: Assessment of PD-L1 expression and tumor mutation burden in non-small cell lung cancer patients treated with immune checkpoint inhibitors

Immuno-oncology biomarker study in a large cohort of LC-SCRUM-Japan: LC-SCRUM-IBIS

scientific article

Immuno-oncology biomarker study in non-small cell lung cancer harboring oncogenic driver alterations: LC-SCRUM-IBIS

scientific article

Immunohistochemical and genetic characteristics of lung cancer mimicking organizing pneumonia

scientific article published on 5 October 2017

Immunohistochemical expression of BCRP and ERCC1 in biopsy specimen predicts survival in advanced non-small-cell lung cancer treated with cisplatin-based chemotherapy.

scientific article published on 26 September 2008

Impact of SWI/SNF complex mutations in patients with non-small cell lung cancer (NSCLC) treated with immune checkpoint inhibitors: Immuno-oncology biomarker study in LC-SCRUM-Japan (LC-SCRUM-IBIS)

scientific article

Impact of large-scale nationwide genomic screening project for small cell lung cancer (LC-SCRUM-Japan)

Impact of prophylactic cranial irradiation on pattern of brain metastases as a first recurrence site for limited-disease small-cell lung cancer

scientific article published on 01 November 2018

Impact of single nucleotide polymorphisms on severe hepatotoxicity induced by EGFR tyrosine kinase inhibitors in patients with non-small cell lung cancer harboring EGFR mutations.

scientific article published on 12 August 2015

Improvement strategies for successful next-generation sequencing analysis of lung cancer

scientific article published on 03 June 2020

Initial safety report on the tolerability of modified FOLFOX6 as adjuvant therapy in patients with curatively resected stage II or III colon cancer (JFMC41-1001-C2: JOIN trial)

scientific article published on 16 May 2015

Interaction between cancer cells and cancer-associated fibroblasts after cisplatin treatment promotes cancer cell regrowth

scientific article published on 22 August 2019

JOIN trial: treatment outcome and recovery status of peripheral sensory neuropathy during a 3-year follow-up in patients receiving modified FOLFOX6 as adjuvant treatment for stage II/III colon cancer

scientific article published on 23 September 2019

Large scale clinico-genomic analyses among patients with BRAF-mutated non-small cell lung cancers (NSCLC) identified by nationwide genomic screening project (LC-SCRUM-Japan)

scientific article

Large-scale nationwide genomic screening system for small cell lung cancer in Japan (LC-SCRUM-Japan)

scientific article

Large-scale nationwide genomic screening system for small cell lung cancer in Japan (LC-SCRUM-Japan)

Long-term outcomes of 50 cases of limited-resection trial for pulmonary ground-glass opacity nodules

scientific article published in October 2012

Low-dose irinotecan as a second-line chemotherapy for recurrent small cell lung cancer

scientific article published on 23 July 2014

MET amplification results in heterogeneous responses to osimertinib in EGFR-mutant lung cancer treated with erlotinib

scientific article published on 31 July 2020

Metabolic Determinants of Sensitivity to Phosphatidylinositol 3-Kinase Pathway Inhibitor in Small-Cell Lung Carcinoma.

scientific article published on 28 February 2018

Multiplex gene-panel testing for lung cancer patients

scientific article published on 21 September 2020

Nationwide genomic screening network for the development of novel targeted therapies in advanced non-small cell lung cancer (LC-SCRUM-Japan)

Nationwide genomic screening network for the development of targeted therapies in NSCLC (LC-SCRUM-Japan)

scientific article

Non-small cell lung cancer with loss of expression of the SWI/SNF complex is associated with aggressive clinicopathological features, PD-L1-positive status, and high tumor mutation burden

scientific article published on 13 October 2019

Personality traits and coping styles explain anxiety in lung cancer patients to a greater extent than other factors

scientific article

Phase II study of gedatolisib for small-cell lung cancer (SCLC) patients (pts) with genetic alterations in PI3K/AKT/mTOR pathway based on a large-scale nationwide genomic screening network in Japan (EAGLE-PAT/LC-SCRUM-Japan)

scientific article

Phase II, open-label, multicenter trial of crizotinib in Japanese patients with advanced non-small cell lung cancer harboring a MET gene alteration: Co-MET study

scientific article published on 30 March 2020

Podoplanin-expressing cancer-associated fibroblasts inhibit small cell lung cancer growth

scientific article published in April 2015

Podoplanin-positive cancer-associated fibroblast recruitment within cancer stroma is associated with a higher number of single nucleotide variants in cancer cells in lung adenocarcinoma

scientific article published on 6 March 2018

Podoplanin-positive cancer-associated fibroblasts in the tumor microenvironment induce primary resistance to EGFR-TKIs in lung adenocarcinoma with EGFR mutation

scientific article

Presence of podoplanin-positive cancer-associated fibroblasts in surgically resected primary lung adenocarcinoma predicts a shorter progression-free survival period in patients with recurrences who received platinum-based chemotherapy

scientific article published on 02 December 2014

Prognostic Factor Analysis in Patients With Small-Cell Lung Cancer Treated With Third-Line Chemotherapy

scientific article published on 16 June 2016

Proteasome inhibition overcomes ALK-TKI resistance in ALK-rearranged/TP53 mutant NSCLC via Noxa expression

scientific article published on 11 December 2020

Protective effect of magnesium preloading on cisplatin-induced nephrotoxicity: a retrospective study

scientific article published on 05 February 2014

RECIST progression patterns during EGFR tyrosine kinase inhibitor treatment of advanced non-small cell lung cancer patients harboring an EGFR mutation

scientific article published on 9 October 2015

Renal Toxicity Caused by Brand-name Versus Generic Cisplatin: A Comparative Analysis ⬇️

scientific article published on February 26, 2013

Response to Crizotinib Re-administration After Progression on Lorlatinib in a Patient With ALK-rearranged Non-small-cell Lung Cancer

scientific article published on 26 June 2019

Salvage chemoradiotherapy with cisplatin and vinorelbine for postoperative locoregional recurrence of non-small cell lung cancer

scientific article published on 27 November 2017

Second-line docetaxel for patients with platinum-refractory advanced non-small cell lung cancer and interstitial pneumonia

scientific article published on 15 May 2015

Secretion of high amounts of hepatocyte growth factor is a characteristic feature of cancer-associated fibroblasts with EGFR-TKI resistance-promoting phenotype: A study of 18 cases of cancer-associated fibroblasts

scientific article published on 24 July 2019

Signaling through the Phosphatidylinositol 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Axis Is Responsible for Aerobic Glycolysis mediated by Glucose Transporter in Epidermal Growth Factor Receptor (EGFR)-mutated Lung Adenocarcinoma

scientific article published on 28 May 2015

Solid predominant histology predicts EGFR tyrosine kinase inhibitor response in patients with EGFR mutation-positive lung adenocarcinoma

scientific article published on 22 August 2013

Successful treatment of an osimertinib-resistant lung adenocarcinoma with an exon 18 EGFR mutation (G719S) with afatinib plus bevacizumab

scientific article published on 18 June 2020

Successful treatment with afatinib after grade 3 hepatotoxicity induced by both gefitinib and erlotinib in EGFR mutation-positive non-small cell lung cancer

scientific article published on 6 June 2016

Successful treatment with nivolumab for SMARCA4-deficient non-small cell lung carcinoma with a high tumor mutation burden: A case report

scientific article published on 10 April 2019

Switch maintenance chemotherapy using S-1 with or without bevacizumab in patients with advanced non-small cell lung cancer: a phase II study

scientific article published in March 2017

The CLIP1-LTK fusion is an oncogenic driver in non-small-cell lung cancer

scientific article published on 24 November 2021

The Lung Cancer Genomic Screening Project for Individualized Medicine in Japan (LC-SCRUM-Japan): Screening for RET and ROS1 fusions in advanced EGFR mutation-negative nonsquamous lung cancer and development of molecular targeted therapy

The PD-1 expression balance between effector and regulatory T cells predicts the clinical efficacy of PD-1 blockade therapies

scientific article published on 31 August 2020

The Re-analysis of LC-SCRUM-Asia Successfully Detected an Overlooked ROS1 Fusion Gene in a Lung Adenocarcinoma Patient and Led to Proper Treatment

The efficacy of immune checkpoint inhibitors and PD-L1 status in patients with advanced non-small cell lung cancer harboring oncogenic driver alterations: Immuno-oncology biomarker study in LC-SCRUM-Japan

Therapeutic and prognostic impact of genetic alterations identified in nationwide genome screening for squamous cell lung cancer (LC-SCRUM-Japan)

Therapeutic and prognostic impacts of specific gene alterations for squamous cell lung cancer: A result of nationwide genome screening in Japan (LC-SCRUM-Japan)

scientific article

Therapeutic impact of mutation subtypes and concomitant STK11 mutations in KRAS–mutated non-small cell lung cancer (NSCLC): A result of nationwide genomic screening project (LC-SCRUM-Japan)

scientific article

Therapeutic priority of the PI3K/AKT/mTOR pathway in small cell lung cancers as revealed by a comprehensive genomic analysis

scientific article

Tuberculosis infection and lung adenocarcinoma: Mendelian randomization and pathway analysis of genome-wide association study data from never-smoking Asian women

scientific article published on 12 July 2019

Tumor mutation burden as a biomarker for lung cancer patients treated with pemetrexed and cisplatin (the JIPANG-TR)

scientific article published on 13 November 2020

Unique intravascular tumor microenvironment predicting recurrence of lung squamous cell carcinoma

scientific article published on 31 October 2015

Uptake of collagen type I via macropinocytosis cause mTOR activation and anti-cancer drug resistance

scientific article published on 19 March 2020

Utility of Site-Specific Biopsy for Diagnosis of Desmoplastic Malignant Mesothelioma.

scientific article published on 27 March 2018

Validity of using immunohistochemistry to predict treatment outcome in patients with non-small cell lung cancer not otherwise specified

scientific article published on 07 September 2019

Vandetanib in patients with previously treated RET-rearranged advanced non-small-cell lung cancer (LURET): an open-label, multicentre phase 2 trial

scientific article published on 4 November 2016

Vascular invasion is a strong prognostic factor after complete resection of node-negative non-small cell lung cancer.

scientific article published in July 2010

Vinorelbine and cisplatin in patients with advanced non-small cell lung cancer with interstitial pneumonia

scientific article published in March 2015

[Current Status and Future Perspectives of SCRUM-Japan].

scientific article published in August 2017

List of works by Koichi Goto

A Minimum Of 100 Tumor Cells in a Single Biopsy Sample Is Required to Assess Programmed Cell Death Ligand 1 Expression in Predicting Patient Response to Nivolumab Treatment in Nonsquamous Non-Small Cell Lung Carcinoma

A nationwide genomic screening project for small cell lung cancer in Japan (LC-SCRUM-Japan)

A nationwide genomic screening project for small cell lung cancer in Japan (LC-SCRUM-Japan)

A novel histopathological evaluation method predicting the outcome of non-small cell lung cancer treated by neoadjuvant therapy: the prognostic importance of the area of residual tumor

Acute and Progressive Tracheal Stenosis after Proton Beam Therapy with Concurrent Chemotherapy for Non-Small Cell Lung Cancer

Aggressive tumor microenvironment of solid predominant lung adenocarcinoma subtype harboring with epidermal growth factor receptor mutations

Aldehyde dehydrogenase 1 expression in cancer cells could have prognostic value for patients with non-small cell lung cancer who are treated with neoadjuvant therapy: identification of prognostic microenvironmental factors after chemoradiation

Amplification of EGFR Wild-Type Alleles in Non-Small Cell Lung Cancer Cells Confers Acquired Resistance to Mutation-Selective EGFR Tyrosine Kinase Inhibitors

Assessment of PD-L1 expression and oncogenic gene status in patients with small-cell lung cancer: Immuno-oncology biomarker study in LC-SCRUM-Japan

Association between GWAS-identified lung adenocarcinoma susceptibility loci and EGFR mutations in never-smoking Asian women, and comparison with findings from Western populations

Association between immune-related adverse events and efficacy of nivolumab in advanced non-small cell lung cancer

Association between the mutational smoking signature and the immune microenvironment in lung adenocarcinoma

Association of Serum Anti-GAD Antibody and HLA Haplotypes with Type 1 Diabetes Mellitus Triggered by Nivolumab in Patients with Non-Small Cell Lung Cancer

Association of variations in HLA class II and other loci with susceptibility to EGFR-mutated lung adenocarcinoma

Breast cancer in first-degree relatives and risk of lung cancer: assessment of the existence of gene sex interactions

Breast cancer resistance protein impacts clinical outcome in platinum-based chemotherapy for advanced non-small cell lung cancer

CD200-positive cancer associated fibroblasts augment the sensitivity of Epidermal Growth Factor Receptor mutation-positive lung adenocarcinomas to EGFR Tyrosine kinase inhibitors

Cancer cell invasion driven by extracellular matrix remodeling is dependent on the properties of cancer-associated fibroblasts

Changes in the tumor microenvironment during lymphatic metastasis of lung squamous cell carcinoma

Characterization of the immunophenotype of the tumor budding and its prognostic implications in squamous cell carcinoma of the lung ⬇️

Characterization of the tumor immune-microenvironment of lung adenocarcinoma associated with usual interstitial pneumonia

Clinical Impact of Gastric Acid-Suppressing Medication Use on the Efficacy of Erlotinib and Gefitinib in Patients With Advanced Non-Small-Cell Lung Cancer Harboring EGFR Mutations.

Clinical features of squamous cell lung cancer with targetable gene alterations in a nationwide genomic screening network in Japan (LC-SCRUM-Japan)

Clinical features of unresectable high-grade lung neuroendocrine carcinoma diagnosed using biopsy specimens

Clinico-pathological and genomic features of NRAS- or HRAS-mutated non-small cell lung cancer (NSCLC) identified in large-scale genomic screening project (LC-SCRUM-Asia)

Clinicopathological characteristics of EGFR mutated adenosquamous carcinoma of the lung.

Collagen type I induces EGFR-TKI resistance in EGFR-mutated cancer cells via mTOR activation through Akt-independent pathway.

Combined effect of cabozantinib and gefitinib in crizotinib-resistant lung tumors harboring ROS1 fusions

Comparison of the expression levels of molecular markers among the peripheral area and central area of primary tumor and metastatic lymph node tumor in patients with squamous cell carcinoma of the lung

Contribution of nationwide genome screening in Japan (LC-SCRUM-Japan) to the development of precision medicine for non-small cell lung cancer

Contribution to the development of precision medicine and clinical utility of nationwide lung cancer genomic screening in Japan (LC-SCRUM-Japan)

Detectability of druggable gene fusions by amplicon-based next generation sequencing in LC-SCRUM-Japan

Development of a nationwide genomic screening network for squamous cell lung cancer in Japan (LC-SCRUM-Japan)

Development of a nationwide genomic screening project (LC-SCRUM-Japan) for small cell lung cancer for precision medicine

Development of nationwide genomic screening project (LC-SCRUM-Japan) contributing to the establishment of precision medicine in Japan

Docetaxel for platinum-refractory advanced thymic carcinoma

Dominant papillary subtype is a significant predictor of the response to gefitinib in adenocarcinoma of the lung

Effect of food on the pharmacokinetics of TAS-102 and its efficacy and safety in patients with advanced solid tumors

Eg5 expression is closely correlated with the response of advanced non-small cell lung cancer to antimitotic agents combined with platinum chemotherapy.

Emergence and Targeting of Acquired and Hereditary Resistance to Multikinase RET Inhibition in Patients With RET-Altered Cancer

Evaluation of variant frequency in SARS-CoV-2 infection-related genes utilizing lung cancer genomic database

Expression of breast cancer resistance protein is associated with a poor clinical outcome in patients with small-cell lung cancer.

Expression profiling of receptor tyrosine kinases in high-grade neuroendocrine carcinoma of the lung: a comparative analysis with adenocarcinoma and squamous cell carcinoma

Factors influencing the concordance of histological subtype diagnosis from biopsy and resected specimens of lung adenocarcinoma

Feasibility of transbronchial brushing cytology specimens for next generation sequencing in peripheral lung cancer

Fibroblast-led cancer cell invasion is activated by epithelial-mesenchymal transition through platelet-derived growth factor BB secretion of lung adenocarcinoma

Genetic profiling and the response to RET inhibitors in RET fusion positive non-small cell lung cancer (NSCLC) identified by international genomic screening project (LC-SCRUM-Asia)

Genetic profiling-based prognostic prediction of patients with advanced small-cell lung cancer in large scale analysis

Genomic Profiling of Large-Cell Neuroendocrine Carcinoma of the Lung

Identification of a lung adenocarcinoma cell line with CCDC6-RET fusion gene and the effect of RET inhibitors in vitro and in vivo

Identification of biological properties of intralymphatic tumor related to the development of lymph node metastasis in lung adenocarcinoma

Identification of prognostic immunophenotypic features in cancer stromal cells of high-grade neuroendocrine carcinomas of the lung

Immuno-oncology biomarker study in a large cohort of LC-SCRUM-Japan: Assessment of PD-L1 expression and tumor mutation burden in non-small cell lung cancer patients treated with immune checkpoint inhibitors

Immuno-oncology biomarker study in a large cohort of LC-SCRUM-Japan: LC-SCRUM-IBIS

Immuno-oncology biomarker study in non-small cell lung cancer harboring oncogenic driver alterations: LC-SCRUM-IBIS

Immunohistochemical and genetic characteristics of lung cancer mimicking organizing pneumonia

Immunohistochemical expression of BCRP and ERCC1 in biopsy specimen predicts survival in advanced non-small-cell lung cancer treated with cisplatin-based chemotherapy.

Impact of SWI/SNF complex mutations in patients with non-small cell lung cancer (NSCLC) treated with immune checkpoint inhibitors: Immuno-oncology biomarker study in LC-SCRUM-Japan (LC-SCRUM-IBIS)

Impact of large-scale nationwide genomic screening project for small cell lung cancer (LC-SCRUM-Japan)

Impact of prophylactic cranial irradiation on pattern of brain metastases as a first recurrence site for limited-disease small-cell lung cancer

Impact of single nucleotide polymorphisms on severe hepatotoxicity induced by EGFR tyrosine kinase inhibitors in patients with non-small cell lung cancer harboring EGFR mutations.

Improvement strategies for successful next-generation sequencing analysis of lung cancer

Initial safety report on the tolerability of modified FOLFOX6 as adjuvant therapy in patients with curatively resected stage II or III colon cancer (JFMC41-1001-C2: JOIN trial)

Interaction between cancer cells and cancer-associated fibroblasts after cisplatin treatment promotes cancer cell regrowth

JOIN trial: treatment outcome and recovery status of peripheral sensory neuropathy during a 3-year follow-up in patients receiving modified FOLFOX6 as adjuvant treatment for stage II/III colon cancer

Large scale clinico-genomic analyses among patients with BRAF-mutated non-small cell lung cancers (NSCLC) identified by nationwide genomic screening project (LC-SCRUM-Japan)

Large-scale nationwide genomic screening system for small cell lung cancer in Japan (LC-SCRUM-Japan)

Large-scale nationwide genomic screening system for small cell lung cancer in Japan (LC-SCRUM-Japan)

Long-term outcomes of 50 cases of limited-resection trial for pulmonary ground-glass opacity nodules

Low-dose irinotecan as a second-line chemotherapy for recurrent small cell lung cancer

MET amplification results in heterogeneous responses to osimertinib in EGFR-mutant lung cancer treated with erlotinib

Metabolic Determinants of Sensitivity to Phosphatidylinositol 3-Kinase Pathway Inhibitor in Small-Cell Lung Carcinoma.

Multiplex gene-panel testing for lung cancer patients

Nationwide genomic screening network for the development of novel targeted therapies in advanced non-small cell lung cancer (LC-SCRUM-Japan)

Nationwide genomic screening network for the development of targeted therapies in NSCLC (LC-SCRUM-Japan)

Non-small cell lung cancer with loss of expression of the SWI/SNF complex is associated with aggressive clinicopathological features, PD-L1-positive status, and high tumor mutation burden

Personality traits and coping styles explain anxiety in lung cancer patients to a greater extent than other factors

Phase II study of gedatolisib for small-cell lung cancer (SCLC) patients (pts) with genetic alterations in PI3K/AKT/mTOR pathway based on a large-scale nationwide genomic screening network in Japan (EAGLE-PAT/LC-SCRUM-Japan)

Phase II, open-label, multicenter trial of crizotinib in Japanese patients with advanced non-small cell lung cancer harboring a MET gene alteration: Co-MET study