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List of works by Yusen Zhou

A 219-mer CHO-expressing receptor-binding domain of SARS-CoV S protein induces potent immune responses and protective immunity

scientific article

A Critical HA1 Neutralizing Domain of H5N1 Influenza in an Optimal Conformation Induces Strong Cross-Protection ⬇️

scientific article published on January 8, 2013

A Novel Nanobody Targeting Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Receptor-Binding Domain Has Potent Cross-Neutralizing Activity and Protective Efficacy against MERS-CoV

scholarly article by Guangyu Zhao published in September 2018

A Recombinant Vaccine of H5N1 HA1 Fused with Foldon and Human IgG Fc Induced Complete Cross-Clade Protection against Divergent H5N1 Viruses ⬇️

scientific article published on January 27, 2011

A conformation-dependent neutralizing monoclonal antibody specifically targeting receptor-binding domain in Middle East respiratory syndrome coronavirus spike protein.

scientific article

A recombinant protein containing highly conserved hemagglutinin residues 81-122 of influenza H5N1 induces strong humoral and mucosal immune responses

scientific article published on June 1, 2013

A recombinant receptor-binding domain of MERS-CoV in trimeric form protects human dipeptidyl peptidase 4 (hDPP4) transgenic mice from MERS-CoV infection

scientific article

A safe and convenient pseudovirus-based inhibition assay to detect neutralizing antibodies and screen for viral entry inhibitors against the novel human coronavirus MERS-CoV

scientific article published on 26 August 2013

A truncated receptor-binding domain of MERS-CoV spike protein potently inhibits MERS-CoV infection and induces strong neutralizing antibody responses: implication for developing therapeutics and vaccines

scientific article

Adaptation of SARS-CoV-2 in BALB/c mice for testing vaccine efficacy

scientific article published on 30 July 2020

Advancements in the development of subunit influenza vaccines

scientific article

Advances in MERS-CoV Vaccines and Therapeutics Based on the Receptor-Binding Domain

scientific article published in 2019

An H5N1 M2e-based multiple antigenic peptide vaccine confers heterosubtypic protection from lethal infection with pandemic 2009 H1N1 virus

scientific article

An M2e-based multiple antigenic peptide vaccine protects mice from lethal challenge with divergent H5N1 influenza viruses.

scientific article

Antigenicity and immunogenicity of SARS-CoV S protein receptor-binding domain stably expressed in CHO cells

scientific article published on 05 May 2009

Blockade of the C5a-C5aR axis alleviates lung damage in hDPP4-transgenic mice infected with MERS-CoV.

scientific article published on 24 April 2018

Cell Entry of Porcine Epidemic Diarrhea Coronavirus Is Activated by Lysosomal Proteases.

scientific article published on 11 October 2016

Cleavage of spike protein of SARS coronavirus by protease factor Xa is associated with viral infectivity

scientific article published on 22 May 2007

Complement Inhibition Alleviates Paraquat-Induced Acute Lung Injury ⬇️

scientific article published on March 18, 2011

Critical neutralizing fragment of Zika virus EDIII elicits cross-neutralization and protection against divergent Zika viruses

scientific article published on 24 January 2018

Development of a heat-stable and orally delivered recombinant M2e-expressing B. subtilis spore-based influenza vaccine

scientific article published in January 2014

Development of a safe and convenient neutralization assay for rapid screening of influenza HA-specific neutralizing monoclonal antibodies

scientific article published on July 2010

Differences in the pathogenicity and inflammatory responses induced by avian influenza A/H7N9 virus infection in BALB/c and C57BL/6 mouse models

scientific article

Evaluation of recombinant Onchocerca volvulus activation associated protein-1 (ASP-1) as a potent Th1-biased adjuvant with a panel of protein or peptide-based antigens and commercial inactivated vaccines

scientific article published on 19 August 2008

Evolutionary Game Analysis of Fresh Food Supply Guarantee in China's Megacities Lockdown Against Covid-19

scientific article published on 26 June 2023

Highly Pathogenic Avian Influenza A(H5N1) Mutants Transmissible by Air Are Susceptible to Human and Animal Neutralizing Antibodies ⬇️

scientific article published on July 18, 2013

Highly conserved M2e and hemagglutinin epitope-based recombinant proteins induce protection against influenza virus infection

scientific article published on 10 September 2017

Human intestinal tract serves as an alternative infection route for Middle East respiratory syndrome coronavirus.

scientific article

Identification and Structural Characterization of a Broadly Neutralizing Antibody Targeting a Novel Conserved Epitope on the Influenza Virus H5N1 Hemagglutinin ⬇️

scientific article published on December 5, 2012

Identification and characterization of novel neutralizing epitopes in the receptor-binding domain of SARS-CoV spike protein: revealing the critical antigenic determinants in inactivated SARS-CoV vaccine

scientific article published on 11 May 2006

Identification of a receptor-binding domain in the S protein of the novel human coronavirus Middle East respiratory syndrome coronavirus as an essential target for vaccine development

scientific article

Identification of an ideal adjuvant for receptor-binding domain-based subunit vaccines against Middle East respiratory syndrome coronavirus.

scientific article

In silico design of a DNA-based HIV-1 multi-epitope vaccine for Chinese populations

scientific article published in January 2015

Induction of protection against divergent H5N1 influenza viruses using a recombinant fusion protein linking influenza M2e to Onchocerca volvulus activation associated protein-1 (ASP-1) adjuvant ⬇️

scientific article published on August 21, 2010

Inhibition of Complement Activation Alleviates Acute Lung Injury Induced by Highly Pathogenic Avian Influenza H5N1 Virus Infection ⬇️

scientific article published on August 1, 2013

Intranasal vaccination of recombinant H5N1 HA1 proteins fused with foldon and Fc induces strong mucosal immune responses with neutralizing activity: Implication for developing novel mucosal influenza vaccines

scientific article published on 11 August 2015

Intranasal vaccination of recombinant adeno-associated virus encoding receptor-binding domain of severe acute respiratory syndrome coronavirus (SARS-CoV) spike protein induces strong mucosal immune responses and provides long-term protection against

scientific article published on January 2008

Intranasal vaccination with recombinant receptor-binding domain of MERS-CoV spike protein induces much stronger local mucosal immune responses than subcutaneous immunization: Implication for designing novel mucosal MERS vaccines.

scientific article

Introduction of neutralizing immunogenicity index to the rational design of MERS coronavirus subunit vaccines

scientific article

MERS-CoV spike protein: a key target for antivirals

scientific article

Modulation of HBV replication by microRNA-15b through targeting hepatocyte nuclear factor 1α

scientific article

Multi-Organ Damage in Human Dipeptidyl Peptidase 4 Transgenic Mice Infected with Middle East Respiratory Syndrome-Coronavirus

scientific article published on 23 December 2015

Optimization of antigen dose for a receptor-binding domain-based subunit vaccine against MERS coronavirus

scientific article published in January 2015

Potential strategies and biosafety protocols used for dual‐use research on highly pathogenic influenza viruses ⬇️

scientific article published on September 14, 2012

Priming with rAAV encoding RBD of SARS-CoV S protein and boosting with RBD-specific peptides for T cell epitopes elevated humoral and cellular immune responses against SARS-CoV infection.

scientific article published on 04 February 2008

Receptor-binding domain of MERS-CoV with optimal immunogen dosage and immunization interval protects human transgenic mice from MERS-CoV infection

scientific article

Receptor-binding domain of SARS-CoV spike protein induces long-term protective immunity in an animal model

scientific article published on 30 October 2006

Recombinant Receptor-Binding Domains of Multiple Middle East Respiratory Syndrome Coronaviruses (MERS-CoVs) Induce Cross-Neutralizing Antibodies against Divergent Human and Camel MERS-CoVs and Antibody Escape Mutants

scientific article published on 19 October 2016

Recombinant adeno-associated virus expressing the receptor-binding domain of severe acute respiratory syndrome coronavirus S protein elicits neutralizing antibodies: Implication for developing SARS vaccines

scientific article published on 21 June 2006

Recombinant receptor-binding domain of SARS-CoV spike protein expressed in mammalian, insect and E. coli cells elicits potent neutralizing antibody and protective immunity

scientific article published on 15 August 2009

Research and development of universal influenza vaccines

scientific article

Salmonella typhi Ty21a bacterial ghost vector augments HIV-1 gp140 DNA vaccine-induced peripheral and mucosal antibody responses via TLR4 pathway ⬇️

scientific article published on July 20, 2012

Searching for an ideal vaccine candidate among different MERS coronavirus receptor-binding fragments--the importance of immunofocusing in subunit vaccine design

scientific article

The latest advancements in Zika virus vaccine development

scientific article published on 07 August 2017

The spike protein of SARS-CoV--a target for vaccine and therapeutic development

scientific article

Treatment of Paraquat-Induced Lung Injury With an Anti-C5a Antibody: Potential Clinical Application

scientific article published on 2 January 2018

Up-regulation of human cervical cancer proto-oncogene contributes to hepatitis B virus-induced malignant transformation of hepatocyte by down-regulating E-cadherin

scientific article published on October 2015

Vaccines for the prevention against the threat of MERS-CoV.

scientific article published on 17 March 2016

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