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List of works by Do Sik Min

A Ras destabilizer KYA1797K overcomes the resistance of EGFR tyrosine kinase inhibitor in KRAS-mutated non-small cell lung cancer

scientific article published in Scientific Reports

A Therapeutic Strategy for Chemotherapy-Resistant Gastric Cancer via Destabilization of Both β-Catenin and RAS

scientific article published on 08 April 2019

A small molecule approach to degrade RAS with EGFR repression is a potential therapy for KRAS mutation-driven colorectal cancer resistance to cetuximab

scholarly article by Sang-Kyu Lee published in November 2018

CXXC5 plays a role as a transcription activator for myelin genes on oligodendrocyte differentiation

scientific article published on 14 October 2015

Caffeic acid phenethyl ester downregulates phospholipase D1 via direct binding and inhibition of NFκB transactivation

scientific article published on 5 October 2013

Euodia sutchuenensis Dode extract stimulates osteoblast differentiation via Wnt/β-catenin pathway activation

scientific article

Hovenia dulcis Thunb extract and its ingredient methyl vanillate activate Wnt/β-catenin pathway and increase bone mass in growing or ovariectomized mice

scientific article (publication date: 2014)

Indirubin-3'-oxime reverses bone loss in ovariectomized and hindlimb-unloaded mice via activation of the Wnt/β-catenin signaling

scientific article published on 01 January 2014

Inhibition of phospholipase D2 augments histone deacetylase inhibitor-induced cell death in breast cancer cells

scientific article published on 01 October 2020

Inhibition of phospholipase D2 induces autophagy in colorectal cancer cells

scientific article

K-Ras stabilization by estrogen via PKCδ is involved in endometrial tumorigenesis

scientific article

MicroRNA-320a and microRNA-4496 attenuate Helicobacter pylori cytotoxin-associated gene A (CagA)-induced cancer-initiating potential and chemoresistance by targeting β-catenin and ATP-binding cassette, subfamily G, member 2.

scientific article published on 23 December 2016

N-Formyl-Methionyl-Leucyl-Phenylalanine (fMLP) Promotes Osteoblast Differentiation via the N-Formyl Peptide Receptor 1-mediated Signaling Pathway in Human Mesenchymal Stem Cells from Bone Marrow ⬇️

scientific article published on March 3, 2011

PLD1 and PLD2 differentially regulate the balance of macrophage polarization in inflammation and tissue injury

scientific article published on 23 December 2020

Phospholipase D Meets Wnt Signaling: A New Target for Cancer Therapy ⬇️

scientific article published on January 11, 2011

Phospholipase D inhibitor enhances radiosensitivity of breast cancer cells

scientific article published on 30 August 2013

Phospholipase D1 Acts through Akt/TopBP1 and RB1 to Regulate the E2F1-Dependent Apoptotic Program in Cancer Cells

scientific article

Phospholipase D1 Inhibition Linked to Upregulation of ICAT Blocks Colorectal Cancer Growth Hyperactivated by Wnt/β-Catenin and PI3K/Akt Signaling

scientific article

Phospholipase D1 drives a positive feedback loop to reinforce the Wnt/beta-catenin/TCF signaling axis

scientific article

Phospholipase D1 has a pivotal role in interleukin-1β-driven chronic autoimmune arthritis through regulation of NF-κB, hypoxia-inducible factor 1α, and FoxO3a

scientific article published on 20 May 2013

Phospholipase D1 inhibition sensitizes glioblastoma to temozolomide and suppresses its tumorigenicity

scientific article published on 29 July 2020

Phospholipase D1 is upregulated by vorinostat and confers resistance to vorinostat in glioblastoma

scientific article published on 01 September 2020

Phospholipase D1 protein coordinates dynamic assembly of HIF-1α-PHD-VHL to regulate HIF-1α stability

scientific article

Phospholipase D2 promotes degradation of hypoxia-inducible factor-1α independent of lipase activity

scientific article

Polygonum aviculare L. and its active compounds, quercitrin hydrate, caffeic acid, and rutin, activate the Wnt/β-catenin pathway and induce cutaneous wound healing

scientific article published on 01 March 2016

Rebamipide attenuates Helicobacter pylori CagA-induced self-renewal capacity via modulation of β-catenin signaling axis in gastric cancer-initiating cells

scientific article published on 2 June 2016

Role of oncogenic K-Ras in cancer stem cell activation by aberrant Wnt/β-catenin signaling.

scientific article published on February 2014

Small-molecule binding of the axin RGS domain promotes β-catenin and Ras degradation

scientific article

Stabilization of Sur8 via PKCα/δ degradation promotes transformation and migration of colorectal cancer cells

scientific article published on 14 December 2017

Sur8/Shoc2 promotes cell motility and metastasis through activation of Ras-PI3K signaling

scientific article published on 5 September 2015

Targeting phospholipase D1 attenuates intestinal tumorigenesis by controlling β-catenin signaling in cancer-initiating cells

scientific article published on 29 June 2015

The Dishevelled-binding protein CXXC5 negatively regulates cutaneous wound healing

scientific article published on 8 June 2015

The pleckstrin homology domain of phospholipase D1 accelerates EGFR endocytosis by increasing the expression of the Rab5 effector, rabaptin-5.

scientific article

Valproic Acid Induces Hair Regeneration in Murine Model and Activates Alkaline Phosphatase Activity in Human Dermal Papilla Cells ⬇️

scientific article published on April 10, 2012

Valproic acid induces cutaneous wound healing in vivo and enhances keratinocyte motility

scientific article

WDR76 is a RAS binding protein that functions as a tumor suppressor via RAS degradation

scientific article published in Nature Communications

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