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List of works by Dario C Altieri

4-Hydroxybutyl(butyl)nitrosamine-induced urinary bladder cancers in mice: characterization of FHIT and survivin expression and chemopreventive effects of indomethacin

scientific article published on 9 December 2004

A CERTain role for ceramide in taxane-induced cell death

scientific article

A Mitochondrial-targeted purine-based HSP90 antagonist for leukemia therapy

scientific article published on 11 December 2017

A cancer ubiquitome landscape identifies metabolic reprogramming as target of Parkin tumor suppression

scientific article published on 25 August 2021

A functional Notch-survivin gene signature in basal breast cancer

scientific article

A neuronal network of mitochondrial dynamics regulates metastasis

scientific article

A p34(cdc2) survival checkpoint in cancer

scientific article (publication date: July 2002)

A retrogen plasmid-based vaccine generates high titer antibody responses against the autologous cancer antigen survivin and demonstrates anti-tumor efficacy

scientific article published on 12 July 2005

A survivin gene signature predicts aggressive tumor behavior

scientific article published in May 2005

A survivin-ran complex regulates spindle formation in tumor cells

scientific article

AML Therapy: Wake Up the Guardian and Cut Loose the Executioners

scientific article published in December 2017

Aberrant overexpression of the cell polarity module scribble in human cancer

scientific article (publication date: June 2011)

Activated checkpoint kinase 2 provides a survival signal for tumor cells

scientific article published on December 2006

Activation of p53-dependent apoptosis by acute ablation of glycogen synthase kinase-3beta in colorectal cancer cells

scientific article published in June 2005

Acute ablation of survivin uncovers p53-dependent mitotic checkpoint functions and control of mitochondrial apoptosis

scientific article published on 27 October 2003

Adaptive mitochondrial reprogramming and resistance to PI3K therapy.

scientific article

Akt phosphorylation of mitochondrial Lonp1 protease enables oxidative metabolism and advanced tumor traits

scientific article published on 12 August 2019

An IAP-IAP complex inhibits apoptosis

scientific article published on 24 June 2004

Antileukemic activity of shepherdin and molecular diversity of hsp90 inhibitors.

scientific article published on August 2006

Bladder cancer detection with urinary survivin, an inhibitor of apoptosis

scientific article

Blocking survivin to kill cancer cells

scientific article published on January 2003

Bone morphogenetic protein 7 protects prostate cancer cells from stress-induced apoptosis via both Smad and c-Jun NH2-terminal kinase pathways

scientific article published on April 2006

CD45 Phosphatase Inhibits STAT3 Transcription Factor Activity in Myeloid Cells and Promotes Tumor-Associated Macrophage Differentiation

scientific article published on February 2016

Cancer cells exploit adaptive mitochondrial dynamics to increase tumor cell invasion

scientific article

Carcinoma-risk variant of EBNA1 deregulates Epstein-Barr Virus episomal latency.

scientific article published on 6 January 2017

Chk2 phosphorylation of survivin-DeltaEx3 contributes to a DNA damage-sensing checkpoint in cancer.

scientific article published on 14 May 2012

Combinatorial drug design targeting multiple cancer signaling networks controlled by mitochondrial Hsp90

scientific article

Combined in silico and experimental approach for drug design: the binding mode of peptidic and non-peptidic inhibitors to hsp90 N-terminal domain.

scientific article

Compartmentalized phosphorylation of IAP by protein kinase A regulates cytoprotection

scientific article

Control of Tumor Bioenergetics and Survival Stress Signaling by Mitochondrial HSP90s ⬇️

scientific article published on September 11, 2012

Correction: Carcinoma-risk variant of EBNA1 deregulates Epstein-Barr Virus episomal latency

scientific article published on 08 July 2019

Corrigendum: Landscape of the mitochondrial Hsp90 metabolome in tumours

scientific article published on 18 June 2015

Coupling apoptosis resistance to the cellular stress response: the IAP-Hsp90 connection in cancer

scientific article published in March 2004

Cyclophilin D extramitochondrial signaling controls cell cycle progression and chemokine-directed cell motility.

scientific article published on 9 January 2013

Cytoprotective mitochondrial chaperone TRAP-1 as a novel molecular target in localized and metastatic prostate cancer

scientific article

Deletion of Cyclophilin D Impairs β-Oxidation and Promotes Glucose Metabolism

scientific article

Deletion of the mitochondrial chaperone TRAP-1 uncovers global reprogramming of metabolic networks

scientific article

Dendritic cell-based full-length survivin vaccine in treatment of experimental tumors

scientific article published on 01 February 2007

Deregulation of MiR-34b/Sox2 Predicts Prostate Cancer Progression

scientific article published on 24 June 2015

Developmental Control of Apoptosis by the Immunophilin Aryl Hydrocarbon Receptor-interacting Protein (AIP) Involves Mitochondrial Import of the Survivin Protein ⬇️

scientific article published on March 18, 2011

Disabling mitochondrial reprogramming in cancer

scientific article

Dynamics-Based Discovery of Allosteric Inhibitors: Selection of New Ligands for the C-terminal Domain of Hsp90.

scientific article published on 30 August 2010

Effect of intravesical treatment of transitional cell carcinoma with bacillus Calmette-Guerin and mitomycin C on urinary survivin levels and outcome

scientific article published on 01 July 2003

Endogenous tumor suppression mediated by PTEN involves survivin gene silencing.

scientific article

Endothelium derived nitric oxide synthase negatively regulates the PDGF-survivin pathway during flow-dependent vascular remodeling

scientific article (publication date: 2012)

Erratum: Trop-2 is up-regulated in invasive prostate cancer and displaces FAK from focal contacts

scientific article published on October 2015

Essential role of the small GTPase Ran in postnatal pancreatic islet development

scientific article

Evaluation of drug combination effect using a Bliss independence dose-response surface model

scientific article published on 13 February 2018

Exosomal αvβ6 integrin is required for monocyte M2 polarization in prostate cancer

scientific article published on 9 March 2018

Exploiting TERT dependency as a therapeutic strategy for NRAS-mutant melanoma

scientific article published on 26 April 2018

Exploiting the mitochondrial unfolded protein response for cancer therapy in mice and human cells ⬇️

scientific article published on April 1, 2011

Fibronectin Protects Prostate Cancer Cells from Tumor Necrosis Factor-α-induced Apoptosis via the AKT/Survivin Pathway ⬇️

scientific article published on September 30, 2003

Full-length dominant-negative survivin for cancer immunotherapy.

scientific article published on December 2003

Gene therapy targeting survivin selectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension

scientific article

Ghost mitochondria drive metastasis through adaptive GCN2/Akt therapeutic vulnerability

scientific article published on 01 February 2022

Global targeting of subcellular heat shock protein-90 networks for therapy of glioblastoma

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

article by Daniel J Klionsky et al published January 2021 in Autophagy

Heat Shock Protein 60 Regulation of the Mitochondrial Permeability Transition Pore in Tumor Cells ⬇️

scientific article published on October 26, 2010

Hsp60 regulation of tumor cell apoptosis

scientific article

Hsp90 regulation of mitochondrial protein folding: from organelle integrity to cellular homeostasis ⬇️

scientific article published on September 30, 2012

IAP regulation of metastasis

scientific article

IDH2 reprograms mitochondrial dynamics in cancer through a HIF-1α-regulated pseudohypoxic state

scientific article published on 17 September 2019

IL-11 protects human microvascular endothelium from alloinjury in vivo by induction of survivin expression

scientific article published on 01 February 2004

Identification of accrual barriers onto breast cancer prevention clinical trials: a case-control study

scientific article

Induction and regulation of tumor necrosis factor-related apoptosis-inducing ligand/Apo-2 ligand-mediated apoptosis in renal cell carcinoma.

scientific article

Inhibition of Age-Related Therapy Resistance in Melanoma by Rosiglitazone-Mediated Induction of Klotho.

scientific article published on 23 February 2017

Inhibition of Mitochondrial Matrix Chaperones and Antiapoptotic Bcl-2 Family Proteins Empower Antitumor Therapeutic Responses

scientific article published on 18 May 2017

Inhibition of apoptosis by survivin improves transplantation of pancreatic islets for treatment of diabetes in mice

scientific article

Inhibitor of apoptosis protein survivin regulates vascular injury

scientific article published on 12 August 2002

Interplay between V-ATPase G1 and small EV-miRNAs modulates ERK1/2 activation in GBM stem cells and non-neoplastic milieu

scientific article published on 04 August 2020

Landscape of the mitochondrial Hsp90 metabolome in tumours ⬇️

scientific article published on January 1, 2013

MFF Regulation of Mitochondrial Cell Death Is a Therapeutic Target in Cancer

scientific article published on 03 October 2019

Metabolic stress regulates cytoskeletal dynamics and metastasis of cancer cells

scientific article

Mitochondria on the move: emerging paradigms of organelle trafficking in tumour plasticity and metastasis

scientific article published on 4 July 2017

Mitochondrial Akt Regulation of Hypoxic Tumor Reprogramming

scientific journal article

Mitochondrial Compartmentalized Protein Folding and Tumor Cell Survival ⬇️

scientific article published on April 1, 2011

Mitochondrial HSP90 Accumulation Promotes Vascular Remodeling in Pulmonary Arterial Hypertension.

scientific article published on 2 February 2018

Mitochondrial HSP90s and tumor cell metabolism ⬇️

scientific article published on October 29, 2012

Mitochondrial Heat Shock Protein-90 Modulates Vascular Smooth Muscle Cell Survival and the Vascular Injury Response in Vivo ⬇️

scientific article published on July 27, 2012

Mitochondrial Hsp90 chaperones as novel molecular targets in prostate cancer

scientific article published in April 2010

Mitochondrial dynamics and metastasis

article

Mitochondrial dynamics of survivin and "four dimensional" control of tumor cell apoptosis.

scientific article

Mitochondrial fission factor is a novel Myc-dependent regulator of mitochondrial permeability in cancer

scientific article published on 18 September 2019

Mitochondrial matrix chaperone and c-myc inhibition causes enhanced lethality in glioblastoma.

scientific article published on 15 March 2017

Mitochondrial survivin inhibits apoptosis and promotes tumorigenesis.

scientific article published on October 2004

Mitosis-independent survivin gene expression in vivo and regulation by p53.

scientific article published in April 2006

Molecular Pathways: Mitochondrial Reprogramming in Tumor Progression and Therapy.

scientific article published on 9 December 2015

Molecular circuits of apoptosis regulation and cell division control: the survivin paradigm

scientific article published on July 2004

Molecular dependence of estrogen receptor-negative breast cancer on a notch-survivin signaling axis

scientific article published on July 2008

Molecular mechanism of inhibition of survivin transcription by the GC-rich sequence-selective DNA binding antitumor agent, hedamycin: evidence of survivin down-regulation associated with drug sensitivity

scientific article

Myc Regulation of a Mitochondrial Trafficking Network Mediates Tumor Cell Invasion and Metastasis

scientific article published on 27 June 2019

Myc-mediated transcriptional regulation of the mitochondrial chaperone TRAP1 controls primary and metastatic tumor growth

scientific article published on 16 May 2019

PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion

scientific article

PSA regulates androgen receptor expression in prostate cancer cells ⬇️

scientific article published on September 28, 2011

Ph.D. Training in Cancer Biology

scientific article published on 01 November 2008

Postnatal expansion of the pancreatic beta-cell mass is dependent on survivin

scientific article published on 3 July 2008

Preclinical characterization of mitochondria-targeted small molecule hsp90 inhibitors, gamitrinibs, in advanced prostate cancer

scientific article

Profiles and legacies in cancer biology

scientific article published on 18 May 2004

Prostate cancer regulatory networks

scientific article

Rational design of shepherdin, a novel anticancer agent.

scientific article

Regulation of lung cancer metastasis by Klf4-Numb-like signaling

scientific article published on 25 February 2013

Regulation of microtubule stability and mitotic progression by survivin.

scientific article

Regulation of survivin function by Hsp90

scientific article

Regulation of survivin stability by the aryl hydrocarbon receptor-interacting protein.

scientific article

Regulation of tumor cell mitochondrial homeostasis by an organelle-specific Hsp90 chaperone network.

scientific article published on October 2007

Regulation of vein graft hyperplasia by survivin, an inhibitor of apoptosis protein.

scientific article published on 25 August 2005

SIRTing through breast cancer is just a survivin' game

scientific article published on 01 October 2008

Small Extracellular Vesicle Regulation of Mitochondrial Dynamics Reprograms a Hypoxic Tumor Microenvironment

scientific article published on 04 August 2020

Small extracellular vesicle-mediated <i>ITGB6</i> siRNA delivery downregulates the αVβ6 integrin and inhibits adhesion and migration of recipient prostate cancer cells

scientific article published on 01 December 2022

Small-Molecule Targeting of Heat Shock Protein 90 Chaperone Function: Rational Identification of a New Anticancer Lead

scientific article published on 01 December 2006

Sorafenib exerts anti-glioma activity in vitro and in vivo

scientific article

Subclinical Kidney Damage in Hypertensive Patients: A Renal Window Opened on the Cardiovascular System. Focus on Microalbuminuria.

scientific article published on 22 November 2016

Suppression of survivin phosphorylation on Thr34 by flavopiridol enhances tumor cell apoptosis.

scientific article

Survival responses of human embryonic stem cells to DNA damage

scientific article

Survivin - The inconvenient IAP

scientific article

Survivin and IAP proteins in cell-death mechanisms

scientific article

Survivin and apoptosis control

scientific article

Survivin and molecular pathogenesis of colorectal cancer.

scientific article

Survivin as a global target of intrinsic tumor suppression networks

scientific article published on 07 September 2009

Survivin at a glance

scientific article published on 04 April 2019

Survivin blockade sensitizes rhabdomyosarcoma cells for lysis by fetal acetylcholine receptor-redirected T cells.

scientific article

Survivin exists in immunochemically distinct subcellular pools and is involved in spindle microtubule function

scientific article published in February 2002

Survivin expression in mouse skin prevents papilloma regression and promotes chemical-induced tumor progression.

scientific article

Survivin expression is up-regulated in vascular injury and identifies a distinct cellular phenotype

scientific article published on 01 April 2005

Survivin family proteins as novel molecular determinants of doxorubicin resistance in organotypic human breast tumors.

scientific article

Survivin in apoptosis control and cell cycle regulation in cancer

scientific article published on January 1, 2003

Survivin modulates microtubule dynamics and nucleation throughout the cell cycle

scientific article

Survivin promotes oxidative phosphorylation, subcellular mitochondrial repositioning, and tumor cell invasion

scientific article

Survivin regulation of vascular injury

scientific article

Survivin, cancer networks and pathway-directed drug discovery.

scientific article

Survivin, versatile modulation of cell division and apoptosis in cancer

scientific article published on November 2003

Syntaphilin Is a Novel Biphasic Biomarker of Aggressive Prostate Cancer and a Metastasis Predictor

scientific article published on 09 May 2019

Syntaphilin Ubiquitination Regulates Mitochondrial Dynamics and Tumor Cell Movements

scientific article published on 13 June 2018

Syntaphilin controls a mitochondrial rheostat for proliferation-motility decisions in cancer

scientific article published on 11 September 2017

T cell expansion: the survivin interface between cell proliferation and cell death.

scientific article published in May 2005

TRAP-1, the mitochondrial Hsp90.

scientific article published on 22 August 2011

Targeted therapy by disabling crossroad signaling networks: the survivin paradigm

scientific article

Targeting mitochondrial biogenesis to overcome drug resistance to MAPK inhibitors

scientific article published on 4 April 2016

Targeting survivin in cancer ⬇️

scientific article published on March 9, 2012

The Mitochondrial Unfoldase-Peptidase Complex ClpXP Controls Bioenergetics Stress and Metastasis.

scientific article

The Relationship Between Aortic Root Size and Hypertension: An Unsolved Conundrum.

scientific article published on 22 November 2016

The cancer-related Runx2 protein enhances cell growth and responses to androgen and TGFbeta in prostate cancer cells.

scientific article

The case for survivin as a regulator of microtubule dynamics and cell-death decisions

scientific article published on 24 August 2006

The mitophagy effector FUNDC1 controls mitochondrial reprogramming and cellular plasticity in cancer cells

scientific article published on 28 July 2020

The search for a better prostate cancer biomarker

scientific article published on 25 September 2011

The αvβ6 integrin in cancer cell-derived small extracellular vesicles enhances angiogenesis

scientific article published on 20 May 2020

Therapeutic targeting of the survivin pathway in cancer: initiation of mitochondrial apoptosis and suppression of tumor-associated angiogenesis

scientific article published on 01 July 2003

Transgenic Expression of the Mitochondrial Chaperone TNFR-associated Protein 1 (TRAP1) Accelerates Prostate Cancer Development

scientific article published on 17 October 2016

Trop-2 is up-regulated in invasive prostate cancer and displaces FAK from focal contacts ⬇️

scientific article

Tumor cell dependence on Ran-GTP-directed mitosis

scientific article

Unique pattern of neutrophil migration and function during tumor progression

article

Validating survivin as a cancer therapeutic target

scientific article (publication date: 2003)

miR-494-3p is a novel tumor driver of lung carcinogenesis

scientific article published on 14 December 2016

microRNA-mediated survivin control of pluripotency

scientific article

α(V)β(6) integrin expression is induced in the POET and Pten(pc-/-) mouse models of prostatic inflammation and prostatic adenocarcinoma.

scientific article

αvβ3 INTEGRIN MEDIATES RADIORESISTANCE OF PROSTATE CANCER CELLS THROUGH REGULATION OF SURVIVIN

scientific article published on 28 September 2018

αvβ6 Integrin Promotes Castrate-Resistant Prostate Cancer through JNK1-Mediated Activation of Androgen Receptor

scientific article

β1 integrin- and JNK-dependent tumor growth upon hypofractionated radiation

scientific article published on 11 July 2016

β1 integrins mediate resistance to ionizing radiation in vivo by inhibiting c-Jun amino terminal kinase 1.

scientific article published on July 2013

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