List of works by Julia L. Hurwitz

A Multi-Vector, Multi-Envelope HIV-1 Vaccine

scientific article

A Sendai virus recombinant vaccine expressing a gene for truncated human metapneumovirus (hMPV) fusion protein protects cotton rats from hMPV challenge

scientific article

A combination of 5-fluorouracil and membrane-bound antibody inhibits B-cell lymphoma growth in a mouse model system

scientific article published on 01 February 2007

A five-residue HIV envelope helper T cell determinant: does this peptide-MHC interaction leave the binding groove half empty?

scientific article published in October 2002

A highly sensitive single-cell assay detects T-helper cell responses missed by conventional interleukin-2-based methods

scientific article published on 01 February 2002

A novel vaccine regimen utilizing DNA, vaccinia virus and protein immunizations for HIV-1 envelope presentation

scientific article published on March 1999

A programmed functional and phenotypic development of bone marrow-derived cytotoxic cell precursors in vitro

scientific article published on 01 June 1987

A recombinant Sendai virus is controlled by CD4+ effector T cells responding to a secreted human immunodeficiency virus type 1 envelope glycoprotein

scientific article

A synthetic decapeptide of influenza virus hemagglutinin elicits helper T cells with the same fine recognition specificities as occur in response to whole virus

scientific article published in August 1985

Activity of transplanted CD8+ versus CD4+ cytotoxic T cells against Epstein-Barr virus-immortalized B cell tumors in SCID mice.

scientific article

Acute Kidney Injury during Parvovirus B19-Induced Transient Aplastic Crisis in Sickle Cell Disease.

scientific article

Adoptive immunotherapy

scientific article published on 01 May 1999

Age-related development of human memory T-helper and B-cell responses toward parainfluenza virus type-1.

scientific article published in December 1994

An Epithelial Integrin Regulates the Amplitude of Protective Lung Interferon Responses against Multiple Respiratory Pathogens

scientific article (publication date: August 2016)

Anti-Thy-1 plus complement-treated, cultured bone marrow cells resemble fetal thymocytes in killer cell function and marker expression

scientific article published on 01 September 1986

Antibody and pre- plus post-transplant prednisone treatments support T cell-depleted stem cell engraftment without drug-induced morbidity

scientific article published in April 2002

Antibody response to influenza infection of mice: different patterns for glycoprotein and nucleocapsid antigens.

scientific article published in April 2003

Antibody-secreting cells in respiratory tract tissues in the absence of eosinophils as supportive partners

scientific article published on 18 July 2016

Antiviral Vaccines: Successes and Prospects

scientific article published on 14 February 2018

Application of the polyvalent approach to HIV-1 vaccine development

scientific article

B Cells, Viruses, and the SARS-CoV-2/COVID-19 Pandemic of 2020

scientific article published on 29 April 2020

Background check: Profound differences in serum antibody isotypes among C57BL/6 mouse substrains discourage substrain interchanges in immunology experiments

scientific article published on 19 August 2019

Bacterial Interactions with Mucosal Epithelial Cells

Baseline Serum Vitamin A and D Levels Determine Benefit of Oral Vitamin A&D Supplements to Humoral Immune Responses Following Pediatric Influenza Vaccination

scientific article published on 30 September 2019

Binding of estrogen receptors to switch sites and regulatory elements in the immunoglobulin heavy chain locus of activated B cells suggests a direct influence of estrogen on antibody expression.

scientific article published on 2 August 2016

CD4+ T cells support establishment of RSV-specific IgG and IgA antibody secreting cells in the upper and lower murine respiratory tract following RSV infection

scientific article published on 11 April 2017

CD8+ T-cells: are they sufficient to prevent, contain or eradicate HIV-1 infection?

scientific article

CH gene rearrangements in IgM-bearing B cells and in the normal splenic DNA component of hybridomas making different isotypes of antibody

scientific article published on 01 November 1980

Capacity of influenza virus-monoclonal antibody mixtures to stimulate memory and cytotoxic T lymphocyte populations

scientific article

Characterization of innate responses to influenza virus infection in a novel lung type I epithelial cell model

scientific article

Characterization of the murine TH response to influenza virus hemagglutinin: evidence for three major specificities

scientific article published on December 1, 1984

Clade, Country and Region-specific HIV-1 Vaccines: Are they necessary?

scientific article

Clearance of HIV type 1 envelope recombinant sendai virus depends on CD4+ T cells and interferon-gamma but not B cells, CD8+ T cells, or perforin

scientific article

Clonally related CD8+ T cells responsible for rapid population of both diffuse nasal-associated lymphoid tissue and lung after respiratory virus infection

scientific article

Clustering of Th Cell Epitopes on Exposed Regions of HIV Envelope Despite Defects in Antibody Activity

scientific article published on October 15, 2003

Complex sex-biased antibody responses: Estrogen receptors bind estrogen response elements centered within immunoglobulin heavy chain gene enhancers

article

Concomitant T-cell receptor alpha and delta gene rearrangements in individual T-cell precursors

scientific article

Cross-reactivity patterns of influenza-specific cytotoxic T lymphocytes from H-2Kb mutant mice

scientific article published on 01 July 1983

Cross-reactivity patterns of vaccinia-specific cytotoxic T lymphocytes from H-2K b mutants

scientific article published on 01 January 1983

Customized mitogen or antibody treatments enhance the sensitivity of lymphoid tumors to 5-fluorouracil in vitro and in vivo

scientific article

Cutting edge: culture with high doses of viral peptide induces previously unprimed CD8(+) T cells to produce cytokine.

scientific article

Development of recombinant Sendai virus vaccines for prevention of human parainfluenza and respiratory syncytial virus infections

scientific article published in October 2008

Developmental T cell receptor gene rearrangements: relatedness of the alpha/beta and gamma/delta T cell precursor.

scientific article published in August 1991

Differential localization and function of antibody-forming cells responsive to inactivated or live-attenuated influenza virus vaccines

scientific article published on 8 November 2012

Diversity of T-cell receptor alpha gene transcripts in the newborn and adult periphery

scientific article published on January 1, 1992

Do the Immunosuppressive Drugs used as Treatment for Graft-versus-host Disease Directly Inhibit Lymphoid Tumor Cell Growth?

scientific article published on January 1, 2003

Does envelope V3 peptide comprise the principal neutralizing determinant for HIV?

scientific article published on 01 January 1995

Does the key to a successful HIV type 1 vaccine lie among the envelope sequences of infected individuals?

scientific article

Drift from the GPGRAF HIV-1 envelope V3 crown sequence in a North American inner city

scientific article

Early activation of TCR alpha gene rearrangement in fetal thymocytes

scientific article published on 01 July 1999

Effect of extended immunosuppressive drug treatment on B cell vs T cell reconstitution in pediatric bone marrow transplant recipients

scientific article published on 01 September 2001

Effect of natural HIV-1 envelope V1-V2 sequence diversity on the binding of V3-specific and non-V3-specific antibodies

scientific article published in October 1997

Eliciting HIV-1 envelope-specific antibodies with mixed vaccinia virus recombinants

scientific article published in February 1997

Eliminating graft-versus-host potential from T cell immunotherapeutic populations

scientific article published on 01 August 1996

Enhanced CD103 Expression and Reduced Frequencies of Virus-Specific CD8+ T Cells Among Airway Lymphocytes After Influenza Vaccination of Mice Deficient in Vitamins A + D.

scientific article published on 13 November 2017

Environmental and allele-specific influences on T cell receptor gene rearrangement: skewed alpha, delta, and gamma gene rearrangement patterns in chimeric mice

scientific article published on 01 December 1991

Environmental influence on T cell receptor alpha gene rearrangement and expression in vitro

scientific article published on October 1, 1992

Eosinophils Promote Antiviral Immunity in Mice Infected with Influenza A Virus

scientific article

Epstein-Barr virus vaccine development: a lytic and latent protein cocktail

scientific article

Establishing Correlates of Protection for Vaccine Development: Considerations for the Respiratory Syncytial Virus Vaccine Field

scientific article published on 16 January 2018

Evidence for recombinatorial hot spots at the T cell receptor Jα locus

article

Fetal thymocyte potential for T cell receptor V gamma 3-J gamma 1 junctional modification

scientific article published on 01 June 1993

First T cell receptor alpha gene rearrangements during T cell ontogeny skew to the 5' region of the J alpha locus

scientific article published on 01 October 1990

First phase I clinical trial of an HIV-1 subtype D gp140 envelope protein vaccine: immune activity induced in all study participants

scientific article published on 01 January 2008

Fluctuating diversity in the HTLV-IIIB virus stock: implications for neutralization and challenge experiments

scientific article published in September 1996

From Influenza Virus Infections to Lupus: Synchronous Estrogen Receptor α and RNA Polymerase II Binding Within the Immunoglobulin Heavy Chain Locus

scientific article published on 27 February 2020

Gene rearrangement patterning and DNase-I hypersensitive sites within the T-cell receptor J alpha locus

scientific article published on 01 February 1995

HIV type 1 envelope sequence diversity in inner city community

scientific article

HIV vaccine discovery and development

scientific article published on 01 June 2005

HIV vaccine rationale, design and testing.

scientific article

HIV vaccines: brief review and discussion of future directions.

scientific article

HIV-1 envelope T cell epitope "hotspots " among mice and humans and among CD4+ and CD8+ T cell subpopulations

scientific article published in March 2007

HIV-1 vaccine design: harnessing diverse lymphocytes to conquer a diverse pathogen

scientific article

HIV-1 vaccine development: tackling virus diversity with a multi-envelope cocktail.

scientific article published on January 2008

Heterologous Prime-Boost HIV-1 Vaccination Regimens in Pre-Clinical and Clinical Trials

scientific article

Hotspots for Vitamin-Steroid-Thyroid Hormone Response Elements Within Switch Regions of Immunoglobulin Heavy Chain Loci Predict a Direct Influence of Vitamins and Hormones on B Cell Class Switch Recombination.

scientific article published on 7 January 2016

How Basic Immunological Principles May Instruct the Design of a Successful HIV-Type 1 Vaccine

scientific article published on 01 April 2020

Human Metapneumovirus: A Largely Unrecognized Threat to Human Health

scientific article published on 13 February 2020

Human PIV-2 recombinant Sendai virus (rSeV) elicits durable immunity and combines with two additional rSeVs to protect against hPIV-1, hPIV-2, hPIV-3, and RSV.

scientific article published on 04 February 2009

Human Parainfluenza Virus Type 1 Immunization of Infant Mice Protects from Subsequent Sendai Virus Infection

scientific article published on September 10, 1995

Hypothesis: RNA and DNA Viral Sequence Integration into the Mammalian Host Genome Supports Long-Term B Cell and T Cell Adaptive Immunity

scientific article

Illumination of parainfluenza virus infection and transmission in living animals reveals a tissue-specific dichotomy

scientific article (publication date: July 2011)

Immature and advanced patterns of T cell receptor gene rearrangement among lymphocytes in splenic culture

scientific article published on 01 April 1989

Individual HIV type 1 envelope-specific T cell responses and epitopes do not segregate by virus subtype

scientific article

Inflammatory molecule reduction with hydroxyurea therapy in children with sickle cell anemia

scientific article published on 16 November 2017

Influences of Vitamin A on Vaccine Immunogenicity and Efficacy

scientific article published on 17 July 2019

Influenza-specific suppression: contribution of major viral proteins to the generation and function of T suppressor cells

scientific article published in September 1985

Inhibition of ex vivo-expanded cytotoxic T-lymphocyte function by high-dose cyclosporine

scientific article published on 01 August 2003

Inhibition of primary clinical isolates of human parainfluenza virus by DAS181 in cell culture and in a cotton rat model

scientific article published on 27 September 2013

Inter- and intra-patient sequence diversity among parainfluenza virus-type 1 nucleoprotein genes

scientific article published on January 1, 1997

Intranasal Sendai virus vaccine protects African green monkeys from infection with human parainfluenza virus-type one.

scientific article published in April 1997

Intranasal administration of retinyl palmitate with a respiratory virus vaccine corrects impaired mucosal IgA response in the vitamin A-deficient host

scientific article published on 19 February 2014

Limited breadth of a T-helper cell response to a human immunodeficiency virus envelope protein

scientific article

Localization of CD4+ T cell epitope hotspots to exposed strands of HIV envelope glycoprotein suggests structural influences on antigen processing

scholarly article

Long lived multi-isotype anti-HIV antibody responses following a prime-double boost immunization strategy

article

Long-term outcome of EBV-specific T-cell infusions to prevent or treat EBV-related lymphoproliferative disease in transplant recipients

scientific article

Low Retinol-Binding Protein and Vitamin D Levels Are Associated with Severe Outcomes in Children Hospitalized with Lower Respiratory Tract Infection and Respiratory Syncytial Virus or Human Metapneumovirus Detection

scientific article published on 31 May 2017

Matters of life and death: How estrogen and estrogen receptor binding to the immunoglobulin heavy chain locus may influence outcomes of infection, allergy, and autoimmune disease

scientific article published on 25 October 2019

Minor components of a multi-envelope HIV vaccine are recognized by type-specific T-helper cells

scientific article published in March 2004

Molecular evidence of ocular Epstein-Barr virus infection

scientific article

Multi-Envelope HIV-1 Vaccine Development: Two Targeted Immune Pathways, One Desired Protective Outcome.

scientific article published on 9 January 2018

Multi-envelope HIV vaccine safety and immunogenicity in small animals and chimpanzees.

scientific article published in January 2000

Multi-envelope HIV-1 vaccine devoid of SIV components controls disease in macaques challenged with heterologous pathogenic SHIV.

scientific article published on 20 July 2005

Murine Monoclonal Antibodies for Antigenic Discrimination of HIV-1 Envelope Proteins

scientific article

Murine TH response to influenza virus: recognition of hemagglutinin, neuraminidase, matrix, and nucleoproteins

scientific article

Non-random lymphocyte distribution among virus-infected cells of the respiratory tract.

scientific article published on December 2013

Nonrandom rearrangement of T cell receptor J alpha genes in bone marrow T cell differentiation cultures.

scientific article published on April 1990

Nuclear Receptors, Ligands and the Mammalian B Cell

scientific article published on 15 July 2020

Oral retinyl palmitate or retinoic acid corrects mucosal IgA responses toward an intranasal influenza virus vaccine in vitamin A deficient mice

scientific article published on 2014

Original Research: Parvovirus B19 infection in children with sickle cell disease in the hydroxyurea era.

scientific article published on 2 March 2016

Patterns of isotype expression by B cell clones responding to thymus-dependent and thymus-independent antigens in vitro

scientific article published on 01 April 1982

Peripheral T cell receptor repertoire among CD4+ and CD8+ subsets during acute infectious mononucleosis

scientific article published on 01 January 1994

Persistent hypogammaglobulinemia in pediatric solid organ transplant recipients

scientific article published on 23 June 2020

Phenotypes and functions of persistent Sendai virus-induced antibody forming cells and CD8+ T cells in diffuse nasal-associated lymphoid tissue typify lymphocyte responses of the gut

scientific article published on 11 January 2011

Phytohemagglutinin inhibits lymphoid tumor growth in vitro and in vivo

scientific article published in October 2003

Preclinical and clinical development of a multi-envelope, DNA-virus-protein (D-V-P) HIV-1 vaccine

scientific article

Prevnar-13 vaccine failure in a mouse model for vitamin A deficiency.

scientific article

Priming of virus-immune memory T cells in newborn mice.

scientific article published on January 1984

Profound abnormality of the B/T lymphocyte ratio during chemotherapy for pediatric acute lymphoblastic leukemia

scientific article published on 01 April 1998

Progression of rearrangements at T cell receptor beta and gamma gene loci during athymic differentiation of bone marrow cells in vitro

scientific article published on 01 March 1988

Rearrangements between the immunoglobulin heavy chain gene JH and C mu regions accompany normal B lymphocyte differentiation in vitro

scientific article published on 01 October 1982

Recombinant Sendai virus as a novel vaccine candidate for respiratory syncytial virus

scientific article

Recombinant Sendai virus expressing the G glycoprotein of respiratory syncytial virus (RSV) elicits immune protection against RSV.

scientific article

Reconstitution of the T cell receptor alpha beta repertoire in recipients of allogeneic BMT

scientific article published on 01 December 1992

Reduced frequencies and heightened CD103 expression among virus-induced CD8(+) T cells in the respiratory tract airways of vitamin A-deficient mice

scientific article

Relationships among dissemination of primary parainfluenza virus infection in the respiratory tract, mucosal and peripheral immune responses, and protection from reinfection: a noninvasive bioluminescence-imaging study

scientific article

Respiratory syncytial virus (RSV) fusion protein expressed by recombinant Sendai virus elicits B-cell and T-cell responses in cotton rats and confers protection against RSV subtypes A and B

scientific article

Respiratory syncytial virus human experimental infection model: provenance, production, and sequence of low-passaged memphis-37 challenge virus

scientific article

Respiratory syncytial virus vaccine development

article

Respiratory syncytial virus: current progress in vaccine development

scientific article published on 05 February 2013

Respiratory tract epithelial cells express retinaldehyde dehydrogenase ALDH1A and enhance IgA production by stimulated B cells in the presence of vitamin A.

scientific article published on 22 January 2014

Respiratory vaccination of mice against influenza virus: dissection of T- and B-cell priming functions

scientific article published in July 2005

Restricted usage of T-cell receptor V alpha sequence and variable-joining pairs after normal T-cell development and bone marrow transplantation

scientific article

Retinol binding protein and vitamin D associations with serum antibody isotypes, serum influenza virus-specific neutralizing activities and airway cytokine profiles

scientific article published on October 2015

Robust IgA and IgG-producing antibody forming cells in the diffuse-NALT and lungs of Sendai virus-vaccinated cotton rats associate with rapid protection against human parainfluenza virus-type 1

scientific article published on September 24, 2010

Role of Vitamins A and D in BCR-ABL Arf-/- Acute Lymphoblastic Leukemia

scientific article published on 11 February 2020

Role of environmental antigens in the ontogeny of the secretory immune response

scientific article published on December 1980

SHIV infection protects against heterologous pathogenic SHIV challenge in macaques: a gold-standard for HIV-1 vaccine development?

scientific article published on September 2009

Saccharomyces cerevisiae-derived virus-like particle parvovirus B19 vaccine elicits binding and neutralizing antibodies in a mouse model for sickle cell disease

scientific article published on 26 May 2017

Safety and immunogenicity of an intranasal Sendai virus-based human parainfluenza virus type 1 vaccine in 3- to 6-year-old children

scientific article

Safety and immunogenicity of intranasal murine parainfluenza virus type 1 (Sendai virus) in healthy human adults

scientific article

Screening of HIV-1 Env glycoproteins for the ability to raise neutralizing antibody using DNA immunization and recombinant vaccinia virus boosting

scientific article

Sendai virus as a backbone for vaccines against RSV and other human paramyxoviruses

scientific article published on 09 December 2015

Sendai virus recombinant vaccine expressing a secreted, unconstrained respiratory syncytial virus fusion protein protects against RSV in cotton rats

scientific article published on 4 December 2014

Sendai virus recombinant vaccine expressing hPIV-3 HN or F elicits protective immunity and combines with a second recombinant to prevent hPIV-1, hPIV-3 and RSV infections

scientific article published on May 2008

Sendai virus-based RSV vaccine protects African green monkeys from RSV infection

scientific article published on 23 November 2011

Sendai virus-based RSV vaccine protects against RSV challenge in an in vivo maternal antibody model

scientific article

Short Communication: Parallel Analyses of Systemic and Local Vaccinations with Envelope Formulated in Adjuvant for Induction of HIV-Specific Antibodies in the Vaginal Mucosa.

scientific article published on 8 November 2016

Short communication: The dead cell: a potent escort for HIV type 1 transinfection

scientific article

Size-heterogeneous sequences mark hot spots for asparagine, serine, and threonine insertions in HIV type 1 envelope

scientific article

Specific and nonspecific T-cell recruitment in viral meningitis: possible implications for autoimmunity.

scientific article published in March 1983

Structural features of HIV envelope defined by antibody escape mutant analysis

scientific article published in August 2001

Subcutaneous administration of a recombinant vaccinia virus vaccine expressing multiple envelopes of HIV-1.

scientific article published on 20 January 2004

Successive switching of antibody isotypes expressed within the lines of a B-cell clone

scientific article

T cell epitope "hotspots" on the HIV Type 1 gp120 envelope protein overlap with tryptic fragments displayed by mass spectrometry

scientific article

T cell immunotherapeutic populations control viral infections in bone marrow transplant recipients

scientific article

T cell receptor repertoire of CD4+ and CD8+ T cell subsets in the allogeneic bone marrow transplant recipient

scientific article published on August 1, 1995

Target peptide sequence within infectious human immunodeficiency virus type 1 does not ensure envelope-specific T-helper cell reactivation: influences of cysteine protease and gamma interferon-induced thiol reductase activities

scientific article

Taxonomy of the order Mononegavirales: second update 2018

scientific article published on 01 April 2019

The HIV pandemic: a forgotten crisis?

scientific article

The kinase mTOR modulates the antibody response to provide cross-protective immunity to lethal infection with influenza virus.

scientific article

UV-inactivated vaccinia virus (VV) in a multi-envelope DNA-VV-protein (DVP) HIV-1 vaccine protects macaques from lethal challenge with heterologous SHIV.

scientific article

Unveiling Unexpected Immune Activities Induced by Your Pneumococcal Vaccine

scientific article published on January 2015

Vaccine Design Informed by Virus-Induced Immunity

scientific article published on 05 May 2020

Vaccines for the Paramyxoviruses and Pneumoviruses: Successes, Candidates, and Hurdles

scientific article published on 11 January 2018

Viral cross-reactivity and antigenic determinants recognized by human parainfluenza virus type 1-specific cytotoxic T-cells.

scientific article

Vitamin A deficiency disrupts vaccine-induced antibody-forming cells and the balance of IgA/IgG isotypes in the upper and lower respiratory tract

scientific article

Vitamin A deficient mice exhibit increased viral antigens and enhanced cytokine/chemokine production in nasal tissues following respiratory virus infection despite the presence of FoxP3+ T cells

scientific article published on 27 October 2015

Vitamin A differentially regulates cytokine expression in respiratory epithelial and macrophage cell lines.

scientific article published on 8 December 2016

Vitamin Supplementation at the Time of Immunization with a Cold-Adapted Influenza Virus Vaccine Corrects Poor Mucosal Antibody Responses in Mice Deficient for Vitamins A and D

scientific article published on 6 January 2016

Will Attention by Vaccine Developers to the Host's Nuclear Hormone Levels and Immunocompetence Improve Vaccine Success?

article