List of works - Marc Hellerstein

5A apolipoprotein mimetic peptide promotes cholesterol efflux and reduces atherosclerosis in mice

scientific article

A comprehensive assessment of mitochondrial protein synthesis and cellular proliferation with age and caloric restriction

scientific article published on 28 December 2011

A critique of the molecular target-based drug discovery paradigm based on principles of metabolic control: advantages of pathway-based discovery

scientific article

A dual sugar challenge test for lipogenic sensitivity to dietary fructose

scientific article

AdPLA ablation increases lipolysis and prevents obesity induced by high-fat feeding or leptin deficiency

scientific article

Adipose overexpression of desnutrin promotes fatty acid use and attenuates diet-induced obesity

scientific article published on 09 January 2009

Adipose weight gain during chronic insulin treatment of mice results from changes in lipid storage without affecting de novo synthesis of palmitate

scientific article

Altered insulin receptor signalling and β-cell cycle dynamics in type 2 diabetes mellitus

scientific article

Alternate-day fasting and chronic disease prevention: a review of human and animal trials

scientific article

Biomarkers of sarcopenia in clinical trials-recommendations from the International Working Group on Sarcopenia

scientific article

Calorie restriction increases fatty acid synthesis and whole body fat oxidation rates

scientific article

Carbohydrate-induced hypertriglyceridemia: modifying factors and implications for cardiovascular risk

scientific article

Cerebrospinal fluid-based kinetic biomarkers of axonal transport in monitoring neurodegeneration.

scientific article

Cholecystokinin is up-regulated in obese mouse islets and expands beta-cell mass by increasing beta-cell survival

scientific article

Cholesterol efflux and atheroprotection: advancing the concept of reverse cholesterol transport

scientific article

Consumption of clarified grapefruit juice ameliorates high-fat diet induced insulin resistance and weight gain in mice

scientific article

Continuous Antigenic Stimulation of DO11.10 TCR Transgenic Mice in the Presence or Absence of IL-1β: Possible Implications for Mechanisms of T Cell Depletion in HIV Disease

scientific article

De novo lipogenesis is essential for platelet production in humans

scientific article published on 14 September 2020

Desnutrin/ATGL is regulated by AMPK and is required for a brown adipose phenotype

scientific article

Dynamics and turnover of memory CD8 T cell responses following yellow fever vaccination

scientific article published on 14 October 2021

Effect of nucleoside reverse transcriptase inhibitors on mitochondrial DNA synthesis in rats and humans

scientific article

Eicosapentaenoic acid but not docosahexaenoic acid restores skeletal muscle mitochondrial oxidative capacity in old mice

scientific article

Emerging applications of kinetic biomarkers in preclinical and clinical drug development.

scientific article

Exploiting complexity and the robustness of network architecture for drug discovery

scientific article

Fibroblast growth factor 21 is not required for the reductions in circulating insulin-like growth factor-1 or global cell proliferation rates in response to moderate calorie restriction in adult mice

scientific article

Identifying nonalcoholic fatty liver disease patients with active fibrosis by measuring extracellular matrix remodeling rates in tissue and blood

scientific article

In vivo 2H2O administration reveals impaired triglyceride storage in adipose tissue of insulin-resistant humans

scientific article

In vivo adipogenesis in rats measured by cell kinetics in adipocytes and plastic-adherent stroma-vascular cells in response to high-fat diet and thiazolidinedione

scientific article published on 28 November 2011

In vivo intraclonal and interclonal kinetic heterogeneity in B-cell chronic lymphocytic leukemia

scientific article

In vivo measurement of DNA synthesis rates of colon epithelial cells in carcinogenesis

scientific article (publication date: 27 May 2005)

In vivo measurement of fluxes through metabolic pathways: the missing link in functional genomics and pharmaceutical research

scientific article

In vivo measurements document the dynamic cellular kinetics of chronic lymphocytic leukemia B cells

scientific article

Intraclonal Complexity in Chronic Lymphocytic Leukemia: Fractions Enriched in Recently Born/Divided and Older/Quiescent Cells ⬇️

scientific article published on September 23, 2011

Long-term synthesis rates of skeletal muscle DNA and protein are higher during aerobic training in older humans than in sedentary young subjects but are not altered by protein supplementation

scientific article

Measurement of Reverse Cholesterol Transport Pathways in Humans: In Vivo Rates of Free Cholesterol Efflux, Esterification, and Excretion ⬇️

scientific article published on August 24, 2012

Metabolic Complications of HIV and AIDS.

scientific article

New stable isotope-mass spectrometric techniques for measuring fluxes through intact metabolic pathways in mammalian systems: introduction of moving pictures into functional genomics and biochemical phenotyping

scientific article published on January 2004

Nutritional recommendations for the management of sarcopenia

scientific article

PPARα inhibition modulates multiple reprogrammed metabolic pathways in kidney cancer and attenuates tumor growth

scientific article published on 25 March 2015

Recent advances for measurement of protein synthesis rates, use of the 'Virtual Biopsy' approach, and measurement of muscle mass

scientific article

Role in tumor growth of a glycogen debranching enzyme lost in glycogen storage disease.

scientific article

SIRT5 Regulates both Cytosolic and Mitochondrial Protein Malonylation with Glycolysis as a Major Target

scientific article

SIRT5 regulates the mitochondrial lysine succinylome and metabolic networks

scientific journal article

Stable isotope-mass spectrometric measurements of molecular fluxes in vivo: emerging applications in drug development

scientific article published in June 2004

Subpopulations of long-lived and short-lived T cells in advanced HIV-1 infection

scientific article

Surprising findings in a 'well-understood' nutrient-assimilation pathway

scientific article published on 01 July 2020

The effects of physiological adaptations to calorie restriction on global cell proliferation rates ⬇️

scientific article published on February 1, 2011

Total body skeletal muscle mass: estimation by creatine (methyl-d3) dilution in humans

scientific article

Turnover rates of hepatic collagen and circulating collagen-associated proteins in humans with chronic liver disease

scientific article published on 24 April 2015

List of works by Marc Hellerstein

5A apolipoprotein mimetic peptide promotes cholesterol efflux and reduces atherosclerosis in mice

A comprehensive assessment of mitochondrial protein synthesis and cellular proliferation with age and caloric restriction

A critique of the molecular target-based drug discovery paradigm based on principles of metabolic control: advantages of pathway-based discovery

A dual sugar challenge test for lipogenic sensitivity to dietary fructose

AdPLA ablation increases lipolysis and prevents obesity induced by high-fat feeding or leptin deficiency

Adipose overexpression of desnutrin promotes fatty acid use and attenuates diet-induced obesity

Adipose weight gain during chronic insulin treatment of mice results from changes in lipid storage without affecting de novo synthesis of palmitate

Altered insulin receptor signalling and β-cell cycle dynamics in type 2 diabetes mellitus

Alternate-day fasting and chronic disease prevention: a review of human and animal trials

Biomarkers of sarcopenia in clinical trials-recommendations from the International Working Group on Sarcopenia

Calorie restriction increases fatty acid synthesis and whole body fat oxidation rates

Carbohydrate-induced hypertriglyceridemia: modifying factors and implications for cardiovascular risk

Cerebrospinal fluid-based kinetic biomarkers of axonal transport in monitoring neurodegeneration.

Cholecystokinin is up-regulated in obese mouse islets and expands beta-cell mass by increasing beta-cell survival

Cholesterol efflux and atheroprotection: advancing the concept of reverse cholesterol transport

Consumption of clarified grapefruit juice ameliorates high-fat diet induced insulin resistance and weight gain in mice

Continuous Antigenic Stimulation of DO11.10 TCR Transgenic Mice in the Presence or Absence of IL-1β: Possible Implications for Mechanisms of T Cell Depletion in HIV Disease

De novo lipogenesis is essential for platelet production in humans

Desnutrin/ATGL is regulated by AMPK and is required for a brown adipose phenotype

Dynamics and turnover of memory CD8 T cell responses following yellow fever vaccination

Effect of nucleoside reverse transcriptase inhibitors on mitochondrial DNA synthesis in rats and humans

Eicosapentaenoic acid but not docosahexaenoic acid restores skeletal muscle mitochondrial oxidative capacity in old mice

Emerging applications of kinetic biomarkers in preclinical and clinical drug development.

Exploiting complexity and the robustness of network architecture for drug discovery

Fibroblast growth factor 21 is not required for the reductions in circulating insulin-like growth factor-1 or global cell proliferation rates in response to moderate calorie restriction in adult mice

Identifying nonalcoholic fatty liver disease patients with active fibrosis by measuring extracellular matrix remodeling rates in tissue and blood

In vivo 2H2O administration reveals impaired triglyceride storage in adipose tissue of insulin-resistant humans

In vivo adipogenesis in rats measured by cell kinetics in adipocytes and plastic-adherent stroma-vascular cells in response to high-fat diet and thiazolidinedione

In vivo intraclonal and interclonal kinetic heterogeneity in B-cell chronic lymphocytic leukemia

In vivo measurement of DNA synthesis rates of colon epithelial cells in carcinogenesis

In vivo measurement of fluxes through metabolic pathways: the missing link in functional genomics and pharmaceutical research

In vivo measurements document the dynamic cellular kinetics of chronic lymphocytic leukemia B cells

Intraclonal Complexity in Chronic Lymphocytic Leukemia: Fractions Enriched in Recently Born/Divided and Older/Quiescent Cells ⬇️

Long-term synthesis rates of skeletal muscle DNA and protein are higher during aerobic training in older humans than in sedentary young subjects but are not altered by protein supplementation

Measurement of Reverse Cholesterol Transport Pathways in Humans: In Vivo Rates of Free Cholesterol Efflux, Esterification, and Excretion ⬇️

Metabolic Complications of HIV and AIDS.

New stable isotope-mass spectrometric techniques for measuring fluxes through intact metabolic pathways in mammalian systems: introduction of moving pictures into functional genomics and biochemical phenotyping

Nutritional recommendations for the management of sarcopenia

PPARα inhibition modulates multiple reprogrammed metabolic pathways in kidney cancer and attenuates tumor growth

Recent advances for measurement of protein synthesis rates, use of the 'Virtual Biopsy' approach, and measurement of muscle mass

Role in tumor growth of a glycogen debranching enzyme lost in glycogen storage disease.

SIRT5 Regulates both Cytosolic and Mitochondrial Protein Malonylation with Glycolysis as a Major Target

SIRT5 regulates the mitochondrial lysine succinylome and metabolic networks

Stable isotope-mass spectrometric measurements of molecular fluxes in vivo: emerging applications in drug development

Subpopulations of long-lived and short-lived T cells in advanced HIV-1 infection

Surprising findings in a 'well-understood' nutrient-assimilation pathway

The effects of physiological adaptations to calorie restriction on global cell proliferation rates ⬇️

Total body skeletal muscle mass: estimation by creatine (methyl-d3) dilution in humans

Turnover rates of hepatic collagen and circulating collagen-associated proteins in humans with chronic liver disease