List of works by Craig R Rayner

1063Estimating Health Outcomes of Antiviral Use in Influenza (flu) Outbreaks by Linking PK/PD and Epidemiology via Transmission Dynamic Model: A Novel Approach.

scientific article published in December 2014

1715Oseltamivir use in an Influenza Outbreak: Linking Pharmacology to Pharmacoeconomics.

scientific article published in December 2014

A critical evaluation of the therapeutic range of indinavir.

scientific article

A drug-disease model describing the effect of oseltamivir neuraminidase inhibition on influenza virus progression.

scientific article

A randomized, crossover study to evaluate the pharmacokinetics of amantadine and oseltamivir administered alone and in combination

scientific article

Absence of adverse effects of oseltamivir on sleep: a double-blind, randomized study in healthy volunteers in Japan

scientific article

Accelerating Clinical Evaluation of Repurposed Combination Therapies for COVID-19

scientific article published on 21 August 2020

Assessing mathematical models of influenza infections using features of the immune response.

scientific article

Assessment of neuropsychiatric adverse events in influenza patients treated with oseltamivir: a comprehensive review

scientific article published on January 2008

Clinical pharmacodynamics of linezolid in seriously ill patients treated in a compassionate use programme

scientific article published in January 2003

Clinical population pharmacokinetics and toxicodynamics of linezolid

scientific article

Clinical trials of disease stages in COVID 19: complicated and often misinterpreted

scientific article published on 20 August 2020

Colistin methanesulfonate is an inactive prodrug of colistin against Pseudomonas aeruginosa.

scientific article

Colistin-associated acute renal failure: revisited

scientific article published on 01 December 2005

Colistin: the re-emerging antibiotic for multidrug-resistant Gram-negative bacterial infections

scientific article

Comments on "Anti-influenza prodrug oseltamivir is activated by carboxylesterase human carboxylesterase 1, and the activation is inhibited by antiplatelet agent clopidogrel"

scientific article published on 01 July 2007

Correction to: Early Treatment of COVID-19 Disease: A Missed Opportunity

scientific article published on 09 November 2020

Differential bidirectional transfer of indinavir in the isolated perfused human placenta

scientific article

Differential protein binding of indinavir and saquinavir in matched maternal and umbilical cord plasma

scientific article

Dosing information for paediatric patients: are they really "therapeutic orphans"?

scientific article

Dosing will be a key success factor in repurposing antivirals for COVID-19

scientific article published on 17 April 2020

Early Treatment of COVID-19 Disease: A Missed Opportunity

scientific article published on 13 October 2020

Elucidation of the pharmacokinetic/pharmacodynamic determinant of colistin activity against Pseudomonas aeruginosa in murine thigh and lung infection models

scientific article

Erratum for Kamal et al., A Drug-Disease Model Describing the Effect of Oseltamivir Neuraminidase Inhibition on Influenza Virus Progression

scientific article published on 26 February 2016

Evaluation of the Cardiac Safety of Long-Acting Endectocide Moxidectin in a Randomized Concentration-QT Study

article published in 2018

Heteroresistance to colistin in multidrug-resistant Acinetobacter baumannii

scientific article

High-performance liquid chromatographic method for simple and rapid determination of linezolid in human plasma.

scientific article

Identification of new oral dosing regimens for the neuraminidase inhibitor oseltamivir in patients with moderate and severe renal impairment

scientific article

Inhibition of placental P-glycoprotein: impact on indinavir transfer to the foetus.

scientific article published on 17 December 2007

Interdisciplinary pharmacometrics linking oseltamivir pharmacology, influenza epidemiology and health economics to inform antiviral use in pandemics.

scientific article published on 20 February 2017

Investigating clinically adequate concentrations of oseltamivir carboxylate in end-stage renal disease patients undergoing hemodialysis using a population pharmacokinetic approach

scientific article

Ivermectin and COVID-19: a report in Antiviral Research, widespread interest, an FDA warning, two letters to the editor and the authors' responses

scientific article published on 21 April 2020

Linezolid for the treatment of multidrug-resistant, gram-positive infections: experience from a compassionate-use program

scientific article

Model-Informed Drug Repurposing: Viral Kinetic Modeling to Prioritize Rational Drug Combinations for COVID-19

scientific article published on 21 July 2020

Nonclinical pharmacokinetics of oseltamivir and oseltamivir carboxylate in the central nervous system

scientific article published on 31 August 2009

Optimizing COVID-19 candidate therapeutics: Thinking Without Borders

scientific article published on 25 March 2020

Oseltamivir Population Pharmacokinetics in the Ferret: Model Application for Pharmacokinetic/Pharmacodynamic Study Design

scientific article

Oseltamivir in seasonal, pandemic, and avian influenza: a comprehensive review of 10-years clinical experience

scientific article

Pharmacokinetic/pharmacodynamic factors influencing emergence of resistance to linezolid in an in vitro model

scientific article published on 22 January 2007

Pharmacokinetics and safety of oseltamivir in patients with end-stage renal disease treated with automated peritoneal dialysis

scientific article

Pharmacokinetics of oseltamivir in young and very elderly subjects.

scientific article published on 29 August 2006

Population pharmacokinetic analysis of oseltamivir and oseltamivir carboxylate following intravenous and oral administration to patients with and without renal impairment

scientific article published on 29 March 2015

Population pharmacokinetics of linezolid in patients treated in a compassionate-use program

scientific article

Population pharmacokinetics of oseltamivir when coadministered with probenecid

scientific article published on 4 June 2008

Population pharmacokinetics of oseltamivir: pediatrics through geriatrics

scientific article published on 13 May 2013

Post-marketing assessment of neuropsychiatric adverse events in influenza patients treated with oseltamivir: an updated review

scientific article published on 02 October 2012

Resistance suppression by high-intensity, short-duration aminoglycoside exposure against hypermutable and non-hypermutable Pseudomonas aeruginosa

scientific article published on 11 August 2016

Role of the intestinal peptide transporter PEPT1 in oseltamivir absorption: in vitro and in vivo studies

scientific article

Safety, tolerability, and pharmacokinetics of intravenous oseltamivir: single- and multiple-dose phase I studies with healthy volunteers

scientific article

Safety, virology and pharmacokinetics of oseltamivir in infants with laboratory-confirmed influenza: a Phase I/II, prospective, open-label, multicentre clinical trial

scientific article published on 27 May 2015

Similarity in pharmacokinetics of oseltamivir and oseltamivir carboxylate in Japanese and Caucasian subjects

scientific article published on 24 April 2007

Simple method for the assay of eperezolid in brain heart infusion broth by high-performance liquid chromatography

scientific article

Simple method for the assay of linezolid in Brain Heart Infusion broth by high-performance liquid chromatography.

scientific article published in January 2004

Stability of colistin methanesulfonate in pharmaceutical products and solutions for administration to patients.

scientific article published on 7 July 2008

Subacute toxicity of colistin methanesulfonate in rats: comparison of various intravenous dosage regimens

scientific article

Successful treatment and cerebrospinal fluid penetration of oral linezolid in a patient with coagulase-negative Staphylococcus ventriculitis

scientific article published on 13 June 2006

The Landscape of Emerging Randomized Clinical Trial Evidence for COVID-19 Disease Stages: A Systematic Review of Global Trial Registries

scientific article published on 22 December 2020

The Rise and Fall of Hydroxychloroquine for the Treatment and Prevention of COVID-19

scientific article published on 24 November 2020

Time to step up: A call to action for the clinical and quantitative pharmacology community to accelerate therapeutics for COVID-19

scientific article published on 22 May 2020

Toward Dynamic Prescribing Information: Codevelopment of Companion Model-Informed Precision Dosing Tools in Drug Development

scientific article published on 30 November 2018

Using in silico viral kinetic models to guide therapeutic strategies during a pandemic: An example in SARS-CoV-2

scientific article published on 29 December 2020

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