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List of works by Mikael Adner

A new house dust mite-driven and mast cell-activated model of asthma in the guinea pig

scientific article published on 21 July 2020

An Optimized Protocol for the Isolation and Functional Analysis of Human Lung Mast Cells

article published in 2018

An assay to evaluate the long-term effects of inflammatory mediators on murine airway smooth muscle: evidence that TNFalpha up-regulates 5-HT(2A)-mediated contraction

scientific article published on December 2002

Antagonising EP1 and EP2 receptors reveal that the TP receptor mediates a component of antigen-induced contraction of the guinea pig trachea

scientific article

Bitter taste receptor agonists mediate relaxation of human and rodent vascular smooth muscle

scientific article published on 15 July 2014

Budesonide prevents cytokine-induced decrease of the relaxant responses to formoterol and terbutaline, but not to salmeterol, in mouse trachea

scientific article published on 8 January 2010

Characterization of the acute inflammatory profile and resolution of airway inflammation after Igf1r-gene targeting in a murine model of HDM-induced asthma.

scientific article

Cholesterol depletion impairs vascular reactivity to endothelin-1 by reducing store-operated Ca2+ entry dependent on TRPC1.

scientific article published on 9 October 2003

Comprehensive evaluation of genetic variation in S100A7 suggests an association with the occurrence of allergic rhinitis

scientific article published on 28 March 2008

DNA microarray analysis of chromosomal susceptibility regions to identify candidate genes for allergic disease: a pilot study

scientific article published in September 2004

Downregulation of peroxisome proliferator-activated receptors (PPARs) in nasal polyposis

scientific article

Effects of tiotropium bromide on airway hyperresponsiveness and inflammation in mice exposed to organic dust

scientific article

Expression of Toll-like receptor 9 in nose, peripheral blood and bone marrow during symptomatic allergic rhinitis

scientific article published on 28 February 2007

FcεR1-mediated mast cell reactivity is amplified through prolonged Toll-like receptor-ligand treatment

scientific article

Gene profiling reveals increased expression of uteroglobin and other anti-inflammatory genes in glucocorticoid-treated nasal polyps.

scientific article

Human lung natural killer cells are predominantly comprised of highly differentiated hypofunctional CD69-CD56dim cells

scientific article published on 23 September 2016

IL-13 and IL-4, but not IL-5 nor IL-17A, induce hyperresponsiveness in isolated human small airways

scientific article published on 02 December 2019

IL-1beta induces murine airway 5-HT2A receptor hyperresponsiveness via a non-transcriptional MAPK-dependent mechanism

scientific article published on 2 April 2007

Immunoprofiling Reveals Novel Mast Cell Receptors and the Continuous Nature of Human Lung Mast Cell Heterogeneity

Inflammation-induced airway smooth muscle responsiveness is strain dependent in mice

scientific article published on 19 January 2011

Innate immune receptors in human airway smooth muscle cells: activation by TLR1/2, TLR3, TLR4, TLR7 and NOD1 agonists

scientific article

Insights into mast cell functions in asthma using mouse models

scientific article published on 09 April 2013

Interleukin-1beta up-regulates tumor necrosis factor receptors in the mouse airways.

scientific article published on 2 May 2008

Intranasal administration of poly(I:C) and LPS in BALB/c mice induces airway hyperresponsiveness and inflammation via different pathways

scientific article

Lipid Mediator Quantification in Isolated Human and Guinea Pig Airways: An Expanded Approach for Respiratory Research

scientific article published on 20 August 2018

Lipid mediator metabolic profiling demonstrates differences in eicosanoid patterns in two phenotypically distinct mast cell populations

scientific article

Lipopolysaccharide-induced down-regulation of uteroglobin in the human nose.

scientific article published in March 2007

Lipoxin A4 reduces house dust mite and TNFα-induced hyperreactivity in the mouse trachea

scientific article published on 15 February 2020

Mannitol triggers mast cell-dependent contractions of human small bronchi and prostacyclin bronchoprotection

scientific article published on 14 June 2019

Mast cell dependent IL-33/ST2 signaling is protective against the development of airway hyperresponsiveness in a house dust mite mouse model of asthma

scientific article published on 16 November 2017

Mast cell mediators cause the early allergic bronchoconstriction in guinea pigs in vivo: a model of relevance to asthma

scientific article published on 14 August 2013

Mechanisms underlying tissue selectivity of anandamide and other vanilloid receptor agonists

scientific article published in September 2002

Nasal challenge with LPS stimulates the release of macrophage inflammatory protein 1alpha

scientific article

PGE2 maintains the tone of the guinea pig trachea through a balance between activation of contractile EP1 receptors and relaxant EP2 receptors ⬇️

scientific article published on February 1, 2013

Proceedings of the Canadian society of allergy and clinical immunology annual scientific meeting 2015

scientific article (publication date: May 2016)

Prolonged exposure to NT-3 attenuates cholinergic nerve-mediated contractions in cultured murine airways

scientific article published in May 2005

Prostaglandin D2 induces contractions through activation of TP receptors in peripheral lung tissue from the guinea pig ⬇️

scientific article published on August 19, 2011

Prostaglandin E2 inhibits mast cell-dependent bronchoconstriction in human small airways through the E prostanoid subtype 2 receptor

scientific article published on 9 May 2015

Prostaglandin modulation of airway inflammation and hyperresponsiveness in mice sensitized without adjuvant

scientific article published on 7 March 2010

Protein kinase C inhibitors decrease endothelin ET(B) receptor mRNA expression and contraction during organ culture of rat mesenteric artery

scientific article published in October 2002

Psoriasin, one of several new proteins identified in nasal lavage fluid from allergic and non-allergic individuals using 2-dimensional gel electrophoresis and mass spectrometry

scientific article

Recombinant human IL-26 facilitates the innate immune response to endotoxin in the bronchoalveolar space of mice in vivo.

scientific article published on 5 December 2017

Stimulation of cannabinoid CB1 receptors prevents nerve-mediated airway hyperreactivity in NGF-induced inflammation in mouse airways

scientific article published on 16 February 2016

Systemic up-regulation of TLR4 causes lipopolysaccharide-induced augmentation of nasal cytokine release in allergic rhinitis

scientific article published on April 27, 2012

TLR3 in human eosinophils: functional effects and decreased expression during allergic rhinitis

scientific article published on 15 September 2009

TNF alpha reduces tachykinin, PGE2-dependent, relaxation of the cultured mouse trachea by increasing the activity of COX-2.

scientific article published on January 2005

TNFα-blockade stabilizes local airway hyperresponsiveness during TLR-induced exacerbations in murine model of asthma.

scientific article

The TLR7 agonist imiquimod induces bronchodilation via a nonneuronal TLR7-independent mechanism: a possible role for quinoline in airway dilation

scientific article published on 15 April 2016

The asthma candidate gene NPSR1 mediates isoform specific downstream signalling

scientific article

The bitter taste receptor (TAS2R) agonists denatonium and chloroquine display distinct patterns of relaxation of the guinea pig trachea

scientific article published on 7 September 2012

Toll-like receptor (TLR) 7 decreases and TLR9 increases the airway responses in mice with established allergic inflammation

scientific article published on 13 September 2013

Toll-like receptor 7 activation reduces the contractile response of airway smooth muscle.

scientific article published on 27 November 2010

Toll-like receptor ligands LPS and poly (I:C) exacerbate airway hyperresponsiveness in a model of airway allergy in mice, independently of inflammation

scientific article

Toll-like receptor stimulation induces airway hyper-responsiveness to bradykinin, an effect mediated by JNK and NF-kappa B signaling pathways

scientific article published in April 2004

Toll-like receptors in cellular subsets of human tonsil T cells: altered expression during recurrent tonsillitis

scientific article published on 27 February 2006

Topical steroids do not downregulate expression of growth-related oncogene-alpha in nasal polyps.

scientific article

Up-regulation of Toll-like receptors 2, 3 and 4 in allergic rhinitis

scientific article

Up-regulation of bradykinin receptors in a murine in-vitro model of chronic airway inflammation.

scientific article published in April 2004

Vaccination against IL-33 Inhibits Airway Hyperresponsiveness and Inflammation in a House Dust Mite Model of Asthma

scientific article published on 27 July 2015

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