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List of works by Richard A Koup

A DNA vaccine for Ebola virus is safe and immunogenic in a phase I clinical trial

scientific article

A Monovalent Chimpanzee Adenovirus Ebola Vaccine Boosted with MVA

scientific article

A Phase I study evaluating the safety and immunogenicity of MVA85A, a candidate TB vaccine, in HIV-infected adults

scientific article (publication date: 2011)

A SARS DNA vaccine induces neutralizing antibody and cellular immune responses in healthy adults in a Phase I clinical trial

scientific article published on 26 September 2008

A West Nile Virus DNA Vaccine Induces Neutralizing Antibody in Healthy Adults during a Phase 1 Clinical Trial

scientific article (publication date: 15 December 2007)

A West Nile Virus DNA Vaccine Utilizing a Modified Promoter Induces Neutralizing Antibody in Younger and Older Healthy Adults in a Phase I Clinical Trial ⬇️

scientific article published on March 11, 2011

A computational framework for the analysis of peptide microarray antibody binding data with application to HIV vaccine profiling

scientific article published on 13 June 2013

A novel approach to the analysis of specificity, clonality, and frequency of HIV-specific T cell responses reveals a potential mechanism for control of viral escape.

scientific article published in March 2002

A steady state of CD4+ T cell memory maturation and activation is established during primary subtype C HIV-1 infection

scientific article published on 2 April 2010

Absence of Immunodominant Anti-Gag p17 (SL9) Responses among Gag CTL-Positive, HIV-Uninfected Vaccine Recipients Expressing the HLA-A*0201 Allele

article

Accelerated vaccination for Ebola virus haemorrhagic fever in non-human primates

scientific article

Accumulation of follicular CD8+ T cells in pathogenic SIV infection

scientific article

Acquisition of direct antiviral effector functions by CMV-specific CD4+ T lymphocytes with cellular maturation

scientific article

Activation and lysis of human CD4 cells latently infected with HIV-1

scientific article

Adenovirus serotype 5 infects human dendritic cells via a coxsackievirus-adenovirus receptor-independent receptor pathway mediated by lactoferrin and DC-SIGN.

scientific article

Adenovirus type 4 and 7 vaccination or adenovirus type 4 respiratory infection elicits minimal cross-reactive antibody responses to nonhuman adenovirus vaccine vectors

scientific article

Adenovirus type-35 vectors block human CD4+ T-cell activation via CD46 ligation

scientific article

Adjuvant Dependent Mucosal V2 Responses and RAS Activation in Vaccine Induced Protection from SIVmac251 Acquisition.

scientific article published in October 2014

Adjuvant-dependent innate and adaptive immune signatures of risk of SIVmac251 acquisition

scientific article published on 30 May 2016

Adult human liver contains CD8pos T cells with naive phenotype, but is not a site for conventional alpha beta T cell development

scientific article published in May 2004

Altered immune cell follicular dynamics in HIV infection following influenza vaccination

scientific article published on 18 June 2018

Amine reactive dyes: an effective tool to discriminate live and dead cells in polychromatic flow cytometry

scientific article published on 19 May 2006

Amine-reactive dyes for dead cell discrimination in fixed samples

scientific article

An avian influenza H7 DNA priming vaccine is safe and immunogenic in a randomized phase I clinical trial

scientific article published in June 2017

Analysis of V2 antibody responses induced in vaccinees in the ALVAC/AIDSVAX HIV-1 vaccine efficacy trial

scientific article

Analysis of immunoglobulin transcripts and hypermutation following SHIV(AD8) infection and protein-plus-adjuvant immunization

scientific article

Antiretroviral-drug resistance among patients recently infected with HIV.

scientific article published in August 2002

Application of area scaling analysis to identify natural killer cell and monocyte involvement in the GranToxiLux antibody dependent cell-mediated cytotoxicity assay

scientific article published on 2 March 2018

Association of HIV-specific and total CD8+ T memory phenotypes in subtype C HIV-1 infection with viral set point

scientific article published on April 2009

Attenuation of CD4+ T-cell function by human adenovirus type 35 is mediated by the knob protein

scientific article

Author Correction: Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses

scientific article published on 01 June 2019

Autocrine production of beta-chemokines protects CMV-Specific CD4 T cells from HIV infection

scientific article

Avidity for antigen shapes clonal dominance in CD8+ T cell populations specific for persistent DNA viruses

scientific article

Baseline Circulating Activated TFH and Tissue-Like Exhausted B Cells Negatively Correlate With Meningococcal C Conjugate Vaccine Induced Antibodies in HIV-Infected Individuals

article

Biodistribution and toxicological safety of adenovirus type 5 and type 35 vectored vaccines against human immunodeficiency virus-1 (HIV-1), Ebola, or Marburg are similar despite differing adenovirus serotype vector, manufacturer's construct, or gene

scientific article published on July 2008

Biohazard sorting

scientific article published on 01 January 2004

Bispecific antibodies: potential immunotherapies for HIV treatment

article

Broadly neutralizing antibodies targeting the HIV-1 envelope V2 apex confer protection against a clade C SHIV challenge

scientific article published on September 2017

CD4 T follicular helper cell dynamics during SIV infection

scientific article

CD8 T cells express randomly selected KIRs with distinct specificities compared with NK cells

scientific article

CD8(+) T cells in preventing HIV infection and disease

scientific article published on June 2012

CD8+ cellular immunity mediates rAd5 vaccine protection against Ebola virus infection of nonhuman primates

scientific article published on 21 August 2011

Characterization of SARS-CoV-specific memory T cells from recovered individuals 4 years after infection

scientific article

Characterization of functional and phenotypic changes in anti-Gag vaccine-induced T cell responses and their role in protection after HIV-1 infection

scientific article

Chimpanzee Adenovirus Vector Ebola Vaccine — Preliminary Report

scientific article

Chimpanzee adenovirus vaccine generates acute and durable protective immunity against ebolavirus challenge

scientific article

Clinical Trial of the Anti-PD-L1 Antibody BMS-936559 in HIV-1 Infected Participants on Suppressive Antiretroviral Therapy

scientific article published on 18 April 2017

Clonotype and repertoire changes drive the functional improvement of HIV-specific CD8 T cell populations under conditions of limited antigenic stimulation

scientific article published on 30 December 2011

Comparative analysis of the magnitude, quality, phenotype, and protective capacity of simian immunodeficiency virus gag-specific CD8+ T cells following human-, simian-, and chimpanzee-derived recombinant adenoviral vector immunization

scientific article published on 6 February 2013

Comparison of adaptive and innate immune responses induced by licensed vaccines for Human Papillomavirus

scientific article published in January 2014

Compromised steady-state germinal center activity with age in nonhuman primates

scientific article published on 15 December 2019

Correction: Human Anti-CD40 Antibody and Poly IC:LC Adjuvant Combination Induces Potent T Cell Responses in the Lung of Nonhuman Primates.

scientific article

Correlates of immune protection in HIV-1 infection: what we know, what we don't know, what we should know

scientific article published in August 2004

DNA Vaccine Delivered by a Needle-Free Injection Device Improves Potency of Priming for Antibody and CD8+ T-Cell Responses after rAd5 Boost in a Randomized Clinical Trial ⬇️

scientific article published on April 8, 2013

DNA priming and influenza vaccine immunogenicity: two phase 1 open label randomised clinical trials ⬇️

scientific article published on 03 October 2011

DNA priming for seasonal influenza vaccine: a phase 1b double-blind randomized clinical trial

scientific article published on 7 May 2015

DNA vaccine priming for seasonal influenza vaccine in children and adolescents 6 to 17 years of age: A phase 1 randomized clinical trial

scientific article published in PLoS ONE

Decreased levels of recent thymic emigrants in peripheral blood of simian immunodeficiency virus-infected macaques correlate with alterations within the thymus

scientific article

Defining the risk of SARS-CoV-2 variants on immune protection

scientific article published on 31 March 2022

Demonstration of cross-protective vaccine immunity against an emerging pathogenic Ebolavirus Species

scientific article

Dendritic cell recruitment in response to skin antigen tests in HIV-1-infected individuals correlates with the level of T-cell infiltration

scientific article

Dendritic cells are less susceptible to human immunodeficiency virus type 2 (HIV-2) infection than to HIV-1 infection

scientific article

Design and evaluation of surface and adjuvant modified PLGA microspheres for uptake by dendritic cells to improve vaccine responses.

scientific article published on 14 October 2015

Detection of T-cell degranulation: CD107a and b.

scientific article published in January 2004

Differential Gag-specific polyfunctional T cell maturation patterns in HIV-1 elite controllers

scientific article published on 25 January 2012

Differential association of programmed death-1 and CD57 with ex vivo survival of CD8+ T cells in HIV infection

scientific article

Differential impact of magnitude, polyfunctional capacity, and specificity of HIV-specific CD8+ T cell responses on HIV set point

scientific article

Differential specificity and immunogenicity of adenovirus type 5 neutralizing antibodies elicited by natural infection or immunization

scientific article published in January 2010

Differential susceptibility to human immunodeficiency virus type 1 infection of myeloid and plasmacytoid dendritic cells

scientific article

Dissociation of skeletal muscle for flow cytometric characterization of immune cells in macaques

scientific article

Dynamic bookmarking of primary response genes by p300 and RNA polymerase II complexes.

scientific article published on 30 October 2009

Early antibody therapy can induce long-lasting immunity to SHIV

scientific article

Early depletion of Mycobacterium tuberculosis-specific T helper 1 cell responses after HIV-1 infection

scientific article published on December 2008

Ebola Virus Binding to Tim-1 on T Lymphocytes Induces a Cytokine Storm.

scientific article published on 26 September 2017

Ebola virus glycoprotein directly triggers T lymphocyte death despite of the lack of infection

scientific article

Effect of HIV Antibody VRC01 on Viral Rebound after Treatment Interruption

scientific article

Effect of a Chikungunya Virus-Like Particle Vaccine on Safety and Tolerability Outcomes: A Randomized Clinical Trial

scientific article published on 01 April 2020

Effect of antiretroviral therapy on HIV reservoirs in elite controllers

scientific article published on 11 July 2013

Effect of therapeutic intensification followed by HIV DNA prime and rAd5 boost vaccination on HIV-specific immunity and HIV reservoir (EraMune 02): a multicentre randomised clinical trial.

scientific article published on 17 February 2015

Effects of exogenous interleukin-7 on human thymus function

scientific article published on 01 April 2002

Efficacy trial of a DNA/rAd5 HIV-1 preventive vaccine

scientific article

Elderly human hematopoietic progenitor cells express cellular senescence markers and are more susceptible to pyroptosis

scientific article published on 12 July 2018

Emerging concepts in the immunopathogenesis of AIDS

scientific article

Enhanced potency of a broadly neutralizing HIV-1 antibody in vitro improves protection against lentiviral infection in vivo

scientific article

Equivalence of ELISpot assays demonstrated between major HIV network laboratories

scientific article

Erratum: Corrigendum: Adjuvant-dependent innate and adaptive immune signatures of risk of SIVmac251 acquisition

scientific article published on 01 October 2016

Establishment and maintenance of a PBMC repository for functional cellular studies in support of clinical vaccine trials

scientific article

Evolution of Antigen-specific B-cell Receptor Repertoires in Early SIV Infection.

scientific article

Expression of CD40L by the ALVAC-Simian Immunodeficiency Virus Vector Abrogates T Cell Responses in Macaques

scientific article published on 28 February 2020

Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8+ T cells

scientific article (publication date: April 2003)

Fc-mediated effector function contributes to the in vivo antiviral effect of an HIV neutralizing antibody

scientific article published on 20 July 2020

Fine-tuning of CD8(+) T-cell effector functions by targeting the 2B4-CD48 interaction.

scientific article

Flow cytometry reveals that H5N1 vaccination elicits cross-reactive stem-directed antibodies from multiple Ig heavy-chain lineages.

scientific article published on 05 February 2014

Follicular CD8 T cells accumulate in HIV infection and can kill infected cells in vitro via bispecific antibodies

scientific article published on January 2017

Glatiramer acetate (Copaxone) therapy induces CD8(+) T cell responses in patients with multiple sclerosis

scientific article

H5N1 Vaccine-Elicited Memory B Cells Are Genetically Constrained by the IGHV Locus in the Recognition of a Neutralizing Epitope in the Hemagglutinin Stem.

scientific article published on 15 June 2015

HIV Gag protein conjugated to a Toll-like receptor 7/8 agonist improves the magnitude and quality of Th1 and CD8+ T cell responses in nonhuman primates

scientific article

HIV antibodies for treatment of HIV infection

scientific article published on January 2017

HIV integration and T cell death: additional commentary.

scientific article published on 09 December 2013

HIV preferentially infects HIV-specific CD4+ T cells

scientific article

HIV vaccine candidate activation of hypoxia and the inflammasome in CD14 monocytes is associated with a decreased risk of SIV acquisition

article

HIV-1 VACCINES. Diversion of HIV-1 vaccine-induced immunity by gp41-microbiota cross-reactive antibodies

scientific article published on 30 July 2015

HIV-1 causes CD4 cell death through DNA-dependent protein kinase during viral integration.

scientific article

HIV-1 latent reservoir size and diversity are stable following brief treatment interruption

article

HIV-1-Specific Antibody Response and Function after DNA Prime and Recombinant Adenovirus 5 Boost HIV Vaccine in HIV-Infected Subjects

scientific article

HIV-Infected Spleens Present Altered Follicular Helper T Cell (Tfh) Subsets and Skewed B Cell Maturation

scientific article published on 26 October 2015

HIV-Specific CD8+ T Cells Exhibit Reduced and Differentially Regulated Cytolytic Activity in Lymphoid Tissue

scientific article published in December 2017

HIV-infected Langerhans cells preferentially transmit virus to proliferating autologous CD4+ memory T cells located within Langerhans cell-T cell clusters

scientific article published in February 2004

HLA class II genes modulate vaccine-induced antibody responses to affect HIV-1 acquisition

scientific article published on July 2015

Heavy metal contaminants can eliminate quantum dot fluorescence

scientific article

High prevalence of autoreactive, neuroantigen-specific CD8+ T cells in multiple sclerosis revealed by novel flow cytometric assay

scientific article published on 19 February 2004

High production rates sustain in vivo levels of PD-1high simian immunodeficiency virus-specific CD8 T cells in the face of rapid clearance

scientific article published on 03 July 2013

Higher T-Cell Responses Induced by DNA/rAd5 HIV-1 Preventive Vaccine Are Associated With Lower HIV-1 Infection Risk in an Efficacy Trial

scientific article published on 12 February 2017

Highly multiplexed quantitation of gene expression on single cells

scientific article published on 13 March 2013

Homologous boosting with adenoviral serotype 5 HIV vaccine (rAd5) vector can boost antibody responses despite preexisting vector-specific immunity in a randomized phase I clinical trial

scientific article

Human Anti-CD40 Antibody and Poly IC:LC Adjuvant Combination Induces Potent T Cell Responses in the Lung of Nonhuman Primates

scientific article published on 29 June 2015

Human Immunodeficiency Virus Type 1 Monoclonal Antibodies Suppress Acute Simian-Human Immunodeficiency Virus Viremia and Limit Seeding of Cell-Associated Viral Reservoirs

scientific article

Human memory T cell responses to SARS-CoV E protein

scientific article published on 30 June 2006

Human plasmacytoid dendritic cells efficiently capture HIV-1 envelope glycoproteins via CD4 for antigen presentation

scientific article published on 31 May 2013

IFNγ⁻TNFα⁻IL2⁻MIP1α⁻CD107a⁺PRF1⁺ CD8 pp65-Specific T-Cell Response Is Independently Associated With Time to Death in Elderly Humans

scientific article

IL-7, the thymus, and naïve T cells

scientific article

Identification and characterization of cancer initiating cells from BRCA1 related mammary tumors using markers for normal mammary stem cells

scientific article published on 4 May 2008

Immediate cytotoxicity but not degranulation distinguishes effector and memory subsets of CD8+ T cells

scientific article

Immune Correlates of Natural HIV Elite Control and Simultaneous HCV Clearance-Supercontrollers

article

Immune Monitoring Reveals Fusion Peptide Priming to Imprint Cross-Clade HIV-Neutralizing Responses with a Characteristic Early B Cell Signature

scientific article published on 01 August 2020

Immune activation driven by CTLA-4 blockade augments viral replication at mucosal sites in simian immunodeficiency virus infection.

scientific article published on April 2008

Immune protection of nonhuman primates against Ebola virus with single low-dose adenovirus vectors encoding modified GPs

scientific article (publication date: June 2006)

Immune reconstitution in HIV-1-infected children on antiretroviral therapy: role of thymic output and viral fitness

article

Immune-correlates analysis of an HIV-1 vaccine efficacy trial

scientific article (publication date: 5 April 2012)

Immunisation with BCG and recombinant MVA85A induces long-lasting, polyfunctional Mycobacterium tuberculosis-specific CD4+ memory T lymphocyte populations

scientific article published on November 2007

Immunization with vaccinia virus induces polyfunctional and phenotypically distinctive CD8(+) T cell responses

scientific article

Immunologic pressure within class I-restricted cognate human immunodeficiency virus epitopes during highly active antiretroviral therapy

scientific article

Immunological and virological mechanisms of vaccine-mediated protection against SIV and HIV.

scientific article published on 18 December 2013

Immunotherapy during the acute SHIV infection of macaques confers long-term suppression of viremia

scientific article published on 01 January 2021

In vitro culture during retroviral transduction improves thymic repopulation and output after total body irradiation and autologous peripheral blood progenitor cell transplantation in rhesus macaques

scientific article published on 23 February 2006

Increased memory differentiation is associated with decreased polyfunctionality for HIV but not for cytomegalovirus-specific CD8+ T cells

scientific article

Infection of specific dendritic cells by CCR5-tropic human immunodeficiency virus type 1 promotes cell-mediated transmission of virus resistant to broadly neutralizing antibodies

scientific article

Integrated systems approach defines the antiviral pathways conferring protection by the RV144 HIV vaccine

article

Interleukin-15 but not interleukin-7 abrogates vaccine-induced decrease in virus level in simian immunodeficiency virus mac251-infected macaques

scientific article published in March 2007

Intracellular cytokine optimization and standard operating procedure

scientific article published on 01 January 2006

Intranasal live influenza vaccine priming elicits localized B cell responses in mediastinal lymph nodes

scientific article published on 14 February 2018

Intrinsic TGF-β signaling promotes age-dependent CD8+ T cell polyfunctionality attrition.

scientific article

Isolation of Monoclonal Antibodies from a SHIV-AD8 Infected Rhesus Macaque with Broad Neutralizing Activity.

scientific article published in October 2014

Keratinocyte growth factor augments immune reconstitution after autologous hematopoietic progenitor cell transplantation in rhesus macaques

scientific article

Lack of in vivo compartmentalization among HIV-1 infected naïve and memory CD4+ T cell subsets

scientific article published on 20 August 2009

Live Adenovirus Type 4 Recombinants Induce Durable Neutralizing Antibody Responses to Influenza H5 with High Levels of Somatic Hypermutation in Humans.

scientific article

Localized Maxillary Ridge Augmentation With a Block Allograft for Dental Implant Placement: Case Reports ⬇️

scientific article published on January 1, 2003

Long-lived effector/central memory T-cell responses to severe acute respiratory syndrome coronavirus (SARS-CoV) S antigen in recovered SARS patients

scientific article published on 16 June 2006

Long-lived memory T lymphocyte responses against SARS coronavirus nucleocapsid protein in SARS-recovered patients

scientific article published on 11 May 2006

Longitudinal dynamics of the HIV-specific B cell response during intermittent treatment of primary HIV infection

scientific article

Loss of circulating CD4 T cells with B cell helper function during chronic HIV infection

scientific article published on 30 January 2014

Lower Baseline Germinal Center Activity and Preserved Th1 Immunity Are Associated With Hepatitis B Vaccine Response in Treated HIV Infection.

scientific article

Lymph Node Activation by PET/CT Following Vaccination With Licensed Vaccines for Human Papillomaviruses

scientific article published on 10 March 2017

Lymphoid tissue fibrosis is associated with impaired vaccine responses

scientific article

Maintenance of HIV-specific CD4+ T cell help distinguishes HIV-2 from HIV-1 infection.

scientific article published in June 2006

Measuring containment of viable infectious cell sorting in high-velocity cell sorters

scientific article published in April 2003

Minor viral and host genetic polymorphisms can dramatically impact the biologic outcome of an epitope-specific CD8 T-cell response

scientific article published on 19 June 2009

Model Informed Development of VRC01 in Newborn Infants Using a Population Pharmacokinetics Approach

scientific article published on 31 August 2020

Modification of the Association Between T-Cell Immune Responses and Human Immunodeficiency Virus Type 1 Infection Risk by Vaccine-Induced Antibody Responses in the HVTN 505 Trial

scientific article published on 8 January 2018

Monitoring CD27 expression to evaluate Mycobacterium tuberculosis activity in HIV-1 infected individuals in vivo

scientific article

Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses

scientific article published on 11 February 2019

Multiclade human immunodeficiency virus type 1 envelope immunogens elicit broad cellular and humoral immunity in rhesus monkeys

scientific article

Multiple Origins of Virus Persistence during Natural Control of HIV Infection

scientific article published on 20 July 2016

Myeloid Cell Crosstalk Regulates the Efficacy of the DNA/ALVAC/gp120 HIV Vaccine Candidate

article

Myeloid and plasmacytoid dendritic cells are susceptible to recombinant adenovirus vectors and stimulate polyfunctional memory T cell responses

scientific article published on August 2007

Myeloid and plasmacytoid dendritic cells transfer HIV-1 preferentially to antigen-specific CD4+ T cells

scientific article

Neutrophils acquire the capacity for antigen presentation to memory CD4+ T cells in vitro and ex vivo.

scientific article published on 31 January 2017

New-Generation High-Potency and Designer Antibodies: Role in HIV-1 Treatment

scientific article published on 13 October 2017

Nonpathogenic SIV infection of sooty mangabeys is characterized by limited bystander immunopathology despite chronic high-level viremia

scientific article published in March 2003

OMIP-009: Characterization of antigen-specific human T-cells

scientific article published on 21 March 2012

Optimal antigens for HIV vaccines based on CD8+ T response, protein length, and sequence variability

scientific article published on 01 September 2002

Optimized determination of T cell epitope responses

scientific article

Optimizing peptide matrices for identifying T-cell antigens

scientific article published on November 2008

PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection

scientific article

Pathogen-specific T cell depletion and reactivation of opportunistic pathogens in HIV infection ⬇️

scientific article published on March 5, 2012

Persistent memory CD4+ and CD8+ T-cell responses in recovered severe acute respiratory syndrome (SARS) patients to SARS coronavirus M antigen

scientific article published on October 2007

Phase 1 safety and immunogenicity evaluation of a multiclade HIV-1 DNA candidate vaccine

scientific article published on 8 November 2006

Phase 1 safety and immunogenicity evaluation of a multiclade HIV-1 candidate vaccine delivered by a replication-defective recombinant adenovirus vector

scientific article published on 8 November 2006

Phase 1 study of pandemic H1 DNA vaccine in healthy adults

scientific article

Phase I clinical evaluation of a six-plasmid multiclade HIV-1 DNA candidate vaccine

scientific article published on 07 March 2007

Phase I clinical evaluation of seasonal influenza hemagglutinin (HA) DNA vaccine prime followed by trivalent influenza inactivated vaccine (IIV3) boost

scientific article published on 11 August 2015

Phase I randomized clinical trial of VRC DNA and rAd5 HIV-1 vaccine delivery by intramuscular (i.m.), subcutaneous (s.c.) and intradermal (i.d.) administration (VRC 011)

scientific article

Phenotypic and functional profile of HIV-inhibitory CD8 T cells elicited by natural infection and heterologous prime/boost vaccination

scientific article

Polyfunctional T cell responses are a hallmark of HIV-2 infection

scientific article published on February 2008

Preferential induction of cross-group influenza A hemagglutinin stem-specific memory B cells after H7N9 immunization in humans

scientific article published on July 2017

Preferential infection and depletion of Mycobacterium tuberculosis-specific CD4 T cells after HIV-1 infection

scientific article

Preferential infection of human Ad5-specific CD4 T cells by HIV in Ad5 naturally exposed and recombinant Ad5-HIV vaccinated individuals

scientific article

Preferential infection shortens the life span of human immunodeficiency virus-specific CD4+ T cells in vivo

scientific article

Prime-Boost Interval Matters: A Randomized Phase 1 Study to Identify the Minimum Interval Necessary to Observe the H5 DNA Influenza Vaccine Priming Effect ⬇️

scientific article published on April 30, 2013

Priming immunization with DNA augments immunogenicity of recombinant adenoviral vectors for both HIV-1 specific antibody and T-cell responses

scientific article (publication date: 2 February 2010)

Principles Governing Establishment versus Collapse of HIV-1 Cellular Spread

scientific article published on 21 November 2019

Prolonged evolution of the memory B cell response induced by a replicating adenovirus-influenza H5 vaccine

scientific article published on 01 April 2019

Quality and quantity of TFH cells are critical for broad antibody development in SHIVAD8 infection

scientific article published on July 2015

Quantitative Multiplexed Imaging Analysis Reveals a Strong Association between Immunogen-Specific B Cell Responses and Tonsillar Germinal Center Immune Dynamics in Children after Influenza Vaccination

scientific article published on 13 December 2017

Quantum dot semiconductor nanocrystals for immunophenotyping by polychromatic flow cytometry

scientific article published on 23 July 2006

Randomized Clinical Trial to Assess the Impact of the Broadly Neutralizing HIV-1 Monoclonal Antibody VRC01 on HIV-1 Persistence in Individuals on Effective ART

article

Rational Design of an Epstein-Barr Virus Vaccine Targeting the Receptor-Binding Site

scientific article published on 12 August 2015

Rational design and in vivo selection of SHIVs encoding transmitted/founder subtype C HIV-1 envelopes

article

Recombinant adenovirus serotype 26 (Ad26) and Ad35 vaccine vectors bypass immunity to Ad5 and protect nonhuman primates against ebolavirus challenge

scientific article

Reconsidering early HIV treatment and supervised treatment interruptions

scientific article

Replication-defective adenovirus vectors with multiple deletions do not induce measurable vector-specific T cells in human trials

scientific article published on April 2009

Reply to Wallis

scientific article published in 2009

SIV-specific CD8+ T cells express high levels of PD1 and cytokines but have impaired proliferative capacity in acute and chronic SIVmac251 infection

scientific article published on 17 April 2007

Safety and Immunogenicity of a rAd35-EnvA Prototype HIV-1 Vaccine in Combination with rAd5-EnvA in Healthy Adults (VRC 012)

scientific article

Safety and immunogenicity of DNA vaccines encoding Ebolavirus and Marburgvirus wild-type glycoproteins in a phase I clinical trial

scientific article

Safety and immunogenicity of Ebola virus and Marburg virus glycoprotein DNA vaccines assessed separately and concomitantly in healthy Ugandan adults: a phase 1b, randomised, double-blind, placebo-controlled clinical trial

scientific article

Safety and immunogenicity of a Gag-Pol candidate HIV-1 DNA vaccine administered by a needle-free device in HIV-1-seronegative subjects

scientific article published on April 2007

Safety and immunogenicity of investigational seasonal influenza hemagglutinin DNA vaccine followed by trivalent inactivated vaccine administered intradermally or intramuscularly in healthy adults: An open-label randomized phase 1 clinical trial

scientific article published on 18 September 2019

Safety and immunogenicity study of Multiclade HIV-1 adenoviral vector vaccine alone or as boost following a multiclade HIV-1 DNA vaccine in Africa

scientific article (publication date: 21 September 2010)

Safety and pharmacokinetics of broadly neutralising human monoclonal antibody VRC07-523LS in healthy adults: a phase 1 dose-escalation clinical trial

scientific article published on 28 August 2019

Safety and pharmacokinetics of the Fc-modified HIV-1 human monoclonal antibody VRC01LS: A Phase 1 open-label clinical trial in healthy adults.

scientific article published on 24 January 2018

Safety and tolerability of chikungunya virus-like particle vaccine in healthy adults: a phase 1 dose-escalation trial

scientific article published on 14 August 2014

Safety, immunogenicity and efficacy of modified vaccinia Ankara (MVA) against Dryvax challenge in vaccinia-naïve and vaccinia-immune individuals

scientific article published on 7 November 2006

Safety, tolerability, pharmacokinetics, and immunogenicity of the therapeutic monoclonal antibody mAb114 targeting Ebola virus glycoprotein (VRC 608): an open-label phase 1 study

article by Martin R Gaudinski et al published 2 March 2019 in The Lancet

Selective Loss of Early Differentiated, Highly Functional PD1high CD4 T Cells with HIV Progression

scientific article published on 17 December 2015

Selective survival of peripheral blood lymphocytes in children with HIV-1 following delivery of an anti-HIV gene to bone marrow CD34(+) cells

scientific article

Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation

scientific article published on 01 October 2003

Sieve analysis of breakthrough HIV-1 sequences in HVTN 505 identifies vaccine pressure targeting the CD4 binding site of Env-gp120.

scientific article published on 17 November 2017

Standard Practice for Cell Sorting in a BSL-3 Facility ⬇️

scientific article published on January 1, 2011

Standardization of cytokine flow cytometry assays

scientific article

Surface expression patterns of negative regulatory molecules identify determinants of virus-specific CD8+ T-cell exhaustion in HIV infection

scientific article

Systemic and mucosal T-lymphocyte activation induced by recombinant adenovirus vaccines in rhesus monkeys

scientific article published on 05 August 2009

T Cell Receptor Recognition Motifs Govern Immune Escape Patterns in Acute SIV Infection

scientific article published on 01 December 2004

T cell dynamics in HIV-1 infection

scientific article published on 19 December 2001

T cell susceptibility to HIV influences outcome of opportunistic infections

scientific article published on 24 October 2013

T cells containing T cell receptor excision circles are inversely related to HIV replication and are selectively and rapidly released into circulation with antiretroviral treatment

scientific article published on 01 May 2003

T follicular helper cells and HIV/SIV-specific antibody responses

scientific article published on May 2014

T-bet and Eomes are differentially linked to the exhausted phenotype of CD8+ T cells in HIV infection

scientific article

T-cell subsets that harbor human immunodeficiency virus (HIV) in vivo: implications for HIV pathogenesis

scientific article published on February 2004

TCF-1 regulates HIV-specific CD8+ T cell expansion capacity

scientific article published on 22 December 2020

The Ebola Interferon Inhibiting Domains Attenuate and Dysregulate Cell-Mediated Immune Responses.

scientific article

The Lack of Maturation of Ebola Virus-Infected Dendritic Cells Results from the Cooperative Effect of at Least Two Viral Domains

article by Ndongala M. Lubaki et al published 1 November 2013 in Journal of Virology

The Thai Phase III HIV Type 1 Vaccine trial (RV144) regimen induces antibodies that target conserved regions within the V2 loop of gp120.

scientific article

The functional profile of primary human antiviral CD8+ T cell effector activity is dictated by cognate peptide concentration

scientific article published in May 2004

The lack of maturation of Ebola virus-infected dendritic cells results from the cooperative effect of at least two viral domains

scientific article published on 24 April 2013

The phenotype of the Cryptococcus-specific CD4+ memory T-cell response is associated with disease severity and outcome in HIV-associated cryptococcal meningitis

scientific article published on 14 March 2013

The quest for a T cell-based immune correlate of protection against HIV: a story of trials and errors ⬇️

scientific article published on December 17, 2010

The role of follicular helper CD4 T cells in the development of HIV-1 specific broadly neutralizing antibody responses

article

Therapeutic vaccination expands and improves the function of the HIV-specific memory T-cell repertoire

scientific article published on 12 March 2013

Thymic Function Failure Is Associated With Human Immunodeficiency Virus Disease Progression

scientific article published on 4 February 2017

Toll-Like Receptor Ligands Modulate Dendritic Cells to Augment Cytomegalovirus- and HIV-1-Specific T Cell Responses ⬇️

scientific article published on October 15, 2003

Toll-like receptor agonists influence the magnitude and quality of memory T cell responses after prime-boost immunization in nonhuman primates

scientific article

Trispecific broadly neutralizing HIV antibodies mediate potent SHIV protection in macaques

scientific article

Tuberculosis Therapy Modifies the Cytokine Profile, Maturation State, and Expression of Inhibitory Molecules on Mycobacterium tuberculosis-Specific CD4+ T-Cells

scientific article

Type I IFN induced by adenovirus serotypes 28 and 35 has multiple effects on T cell immunogenicity

scientific article

Type I interferon-dependent activation of NK cells by rAd28 or rAd35, but not rAd5, leads to loss of vector-insert expression

scientific article published on 08 December 2013

Use of ChAd3-EBO-Z Ebola virus vaccine in Malian and US adults, and boosting of Malian adults with MVA-BN-Filo: a phase 1, single-blind, randomised trial, a phase 1b, open-label and double-blind, dose-escalation trial, and a nested, randomised, doub

scientific article

Vaccination in humans generates broad T cell cytokine responses

scientific article published on 01 November 2004

Vaccination induces HIV broadly neutralizing antibody precursors in humans ⬇️

journal article published in 2022

Vaccine Design for CD8 T Lymphocyte Responses ⬇️

scientific article published on September 1, 2011

Vaccine priming is restricted to draining lymph nodes and controlled by adjuvant-mediated antigen uptake.

scientific article published on June 2017

Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses

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Vector choice determines immunogenicity and potency of genetic vaccines against Angola Marburg virus in nonhuman primates

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Viable infectious cell sorting in a BSL-3 facility

scientific article published in January 2004

Virologic effects of broadly neutralizing antibody VRC01 administration during chronic HIV-1 infection

scientific article published on December 2015

Virological Control by the CD4-Binding Site Antibody N6 in Simian-Human Immunodeficiency Virus-Infected Rhesus Monkeys

scientific article published on 24 May 2017

Virus inhibition activity of effector memory CD8(+) T cells determines simian immunodeficiency virus load in vaccinated monkeys after vaccine breakthrough infection

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