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List of works by Dennis R Roop

"Structural imprinting" of the cutaneous immune effector function

scientific article published on 03 December 2020

12-O-tetradecanoylphorbol-13-acetate promotion of transgenic mice expressing epidermal-targeted v-fos induces rasHA-activated papillomas and carcinomas without p53 mutation: association of v-fos expression with promotion and tumor autonomy

scientific article published on 01 May 1995

12-O-tetradecanoylphorbol-13-acetate promotion of transgenic mouse epidermis coexpressing transforming growth factor-alpha and v-fos: acceleration of autonomous papilloma formation and malignant conversion via c-Ha-ras activation.

scientific article published in December 1999

A fitness model for melanoma-initiating cells

scientific article published on 01 June 2011

A genetic variant of Aurora kinase A promotes genomic instability leading to highly malignant skin tumors

scientific article published on 08 September 2009

A human epidermal differentiation-specific keratin gene is regulated by calcium but not negative modulators of differentiation in transgenic mouse keratinocytes ⬇️

scientific article published on February 1, 1991

A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity.

scientific article

A mutational hot spot in keratin 10 (KRT 10) in patients with epidermolytic hyperkeratosis

scientific article

A novel dinucleotide mutation in keratin 10 in the annular epidermolytic ichthyosis variant of bullous congenital ichthyosiform erythroderma

scientific article published on 01 March 1997

A novel helix termination mutation in keratin 10 in annular epidermolytic ichthyosis, a variant of bullous congenital ichthyosiform erythroderma

scientific article published on 01 December 1998

A novel mutation in the 1A domain of keratin 2e in ichthyosis bullosa of Siemens

scientific article

A novel substitution in keratin 10 in epidermolytic hyperkeratosis

scientific article published on 01 April 1999

A pilot study of cetuximab and the hedgehog inhibitor IPI-926 in recurrent/metastatic head and neck squamous cell carcinoma

scientific article published on 15 December 2015

A procedure for the culture of hair follicles as functionally intact organoids

scientific article published on 01 October 1988

A role for TGFbeta1 in langerhans cell biology. Further characterization of the epidermal Langerhans cell defect in TGFbeta1 null mice ⬇️

scientific article published on August 1, 1997

A spontaneous Fatp4/Scl27a4 splice site mutation in a new murine model for congenital ichthyosis

scientific article

A transgenic mouse model that recapitulates the clinical features of both neonatal and adult forms of the skin disease epidermolytic hyperkeratosis

scientific article published on 01 December 1996

ALDH1A isozymes are markers of human melanoma stem cells and potential therapeutic targets.

scientific article

Aberrant differentiation in mouse skin carcinogenesis

scientific article published on January 1988

Aberrant expression during two-stage mouse skin carcinogenesis of a type I 47-kDa keratin, K13, normally associated with terminal differentiation of internal stratified epithelia.

scientific article

Abnormal keratin 1 and 10 cytoskeleton in cultured keratinocytes from epidermolytic hyperkeratosis caused by keratin 10 mutations

scientific article

Activation of Nrf2 in keratinocytes causes chloracne (MADISH)-like skin disease in mice

scientific article published on 06 February 2014

Acute or chronic topical retinoic acid treatment of human skin in vivo alters the expression of epidermal transglutaminase, loricrin, involucrin, filaggrin, and keratins 6 and 13 but not keratins 1, 10, and 14

scientific article published on March 1, 1992

Adenovirus-mediated ex vivo immunogene and in vivo combination gene therapy strategies induce a systemic anti-tumor immune defense in the mouse B16 melanoma model.

scientific article published in January 1998

Alterations in epidermal biochemistry as a consequence of stage-specific genetic changes in skin carcinogenesis ⬇️

scientific article published on June 1, 1991

Altered distribution of keratinization markers in epidermolytic hyperkeratosis

scientific article published on 01 January 1995

Altered regulation of growth and expression of differentiation-associated keratins in benign mouse skin tumors ⬇️

scientific article published on November 1, 1991

Altering Cell Fate: From Thymus Epithelium to Skin Stem Cells ⬇️

scientific article published on 01 October 2010

Amino acid sequences of mouse and human epidermal type II keratins of Mr 67,000 provide a systematic basis for the structural and functional diversity of the end domains of keratin intermediate filament subunits

scientific article

Amniotic fluid activates the nrf2/keap1 pathway to repair an epidermal barrier defect in utero

scientific article published on December 2012

An activated Harvey ras oncogene produces benign tumours on mouse epidermal tissue

scientific article published on October 1986

An asparagine to threonine substitution in the 1A domain of keratin 1: a novel mutation that causes epidermolytic hyperkeratosis

scientific article published on 01 April 1999

An inducible mouse model for epidermolysis bullosa simplex: implications for gene therapy

scientific article published in February 2001

An inducible mouse model for skin cancer reveals distinct roles for gain- and loss-of-function p53 mutations

scientific article published on July 2007

An unexpected role for keratin 10 end domains in susceptibility to skin cancer

scientific article

Analysis of centrosome abnormalities and angiogenesis in epidermal-targeted p53172H mutant and p53-knockout mice after chemical carcinogenesis: evidence for a gain of function

scientific article published on 01 November 1998

Apoptotic cells activate the "phoenix rising" pathway to promote wound healing and tissue regeneration

scientific article

Application of cantharidin or 12-O-tetradecanoylphorbol-13-acetate on mouse epidermis induces a cell population shift that causes altered keratin distribution

scientific article published on September 1994

Are stem cell niches shared for skin cancers?

scientific article published on 8 June 2010

Asymmetric cell division in skin development: a new look at an old observation.

scientific article published in October 2005

Aurora Kinase-A Deficiency during Skin Development Impairs Cell Division and Stratification ⬇️

scientific article published on July 26, 2012

Biosynthetic pathways of filaggrin and loricrin--two major proteins expressed by terminally differentiated epidermal keratinocytes

scientific article published on 01 July 1990

Changes in Photo-Aged Human Skin Following Topical Application of All-Trans Retinoic Acid ⬇️

scientific article published on 01 November 1990

Characterization of an inducible, epidermal-specific knockout system: differential expression of lacZ in different Cre reporter mouse strains

scientific article published on 01 February 2000

Characterization of human loricrin. Structure and function of a new class of epidermal cell envelope proteins

scientific article

Characterization of loricrin regulation in vitro and in transgenic mice

scientific article published on May 1999

Characterization of the mouse loricrin gene: linkage with profilaggrin and the flaky tail and soft coat mutant loci on chromosome 3.

scientific article published on September 1994

Complete amino acid sequence of a mouse epidermal keratin subunit and implications for the structure of intermediate filaments ⬇️

scientific article published on April 28, 1983

Conflicting roles for p63 in skin development and carcinogenesis

scientific article published on 3 February 2007

Consequences of exposure to initiating levels of carcinogens in vitro and in vivo: altered differentiation and growth, mutations, and transformation

scientific article

Cooperation between Ha-ras and fos or transforming growth factor alpha overcomes a paradoxic tumor-inhibitory effect of p53 loss in transgenic mouse epidermis

scientific article published on 01 October 2000

Cooperation between v-fos and v-rasHA induces autonomous papillomas in transgenic epidermis but not malignant conversion ⬇️

scientific article published on November 1, 1993

Cooperation of Ha-ras and Bcl-2 during multistep skin carcinogenesis

scientific article published on 01 December 2007

Correction of Hair Shaft Defects through Allele-Specific Silencing of Mutant Krt75.

scientific article published on January 2016

Correction: A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity

scientific article published on 21 March 2016

Cross-regulation between Notch and p63 in keratinocyte commitment to differentiation

scientific journal article

Cultivation of murine hair follicles as organoids in a collagen matrix

scientific article published on 01 October 1987

Defects in Stratum Corneum Desquamation Are the Predominant Effect of Impaired ABCA12 Function in a Novel Mouse Model of Harlequin Ichthyosis

scientific article

Definition of the 5' and 3' ends of transcripts of the ovalbumin gene

scientific article published on 01 January 1980

Definition of the transcription unit of the natural ovalbumin gene

scientific article published on 01 January 1981

DeltaNp63 knockdown mice: A mouse model for AEC syndrome

scientific article

Density-dependent modulation of synthesis of keratins 1 and 10 in the human keratinocyte line HACAT and in ras-transfected tumorigenic clones

scientific article published on March 1989

Deregulated expression of c-Myc depletes epidermal stem cells

scientific article

Deregulated minichromosomal maintenance protein MCM7 contributes to oncogene driven tumorigenesis

scientific article

Development of gene-switch transgenic mice that inducibly express transforming growth factor beta1 in the epidermis

scientific article published on July 1999

Development of transgenic mice that inducibly express an active form of c-Src in the epidermis

scientific article

Development of transgenic mouse models of skin carcinogenesis: potential applications

scientific article published in January 1994

Differential keratin gene expression in developing, differentiating, preneoplastic, and neoplastic mouse mammary epithelium ⬇️

scientific article published on April 1, 1990

Differentiation of Mouse Induced Pluripotent Stem Cells into a Multipotent Keratinocyte Lineage ⬇️

scientific article published on December 9, 2010

Differentiation of human induced pluripotent stem cells into a keratinocyte lineage

scientific article

Differentiation-specific expression of human keratin 1 is mediated by a composite AP-1/steroid hormone element

scientific article published on 01 March 1994

Discovery of a novel murine keratin 6 (K6) isoform explains the absence of hair and nail defects in mice deficient for K6a and K6b.

scientific article

Disruption of dihydronicotinamide riboside:quinone oxidoreductase 2 (NQO2) leads to myeloid hyperplasia of bone marrow and decreased sensitivity to menadione toxicity

scientific article published on 25 September 2002

Disruption of epidermal specific gene expression and delayed skin development in AP-2 gamma mutant mice

scientific journal article

Double-inducible gene activation system for caspase 3 and 9 in epidermis

scientific article published on April 2007

Down-regulation of p63 is required for epidermal UV-B-induced apoptosis

scientific article

Effect of estrogen on gene expression in the chick oviduct. Regulation of the ovomucoid gene

scientific article published on December 26, 1978

Epidermal differentiation: transgenic/knockout mouse models reveal genes involved in stem cell fate decisions and commitment to differentiation

scientific article

Epidermal expression of transforming growth factor-alpha in transgenic mice: induction of spontaneous and 12-O-tetradecanoylphorbol-13-acetate-induced papillomas via a mechanism independent of Ha-ras activation or overexpression

scientific article published on 01 May 1994

Epidermal morphogenesis and keratin expression in c-Ha-ras-transfected tumorigenic clones of the human HaCaT cell line ⬇️

scientific article published on August 15, 1991

Epidermis: an attractive target tissue for gene therapy

scientific article published on November 1994

Epithelial stem cell mutations that promote squamous cell carcinoma metastasis

scientific article published on 03 September 2013

Evidence that deoxyribonucleic acid sequences flanking the ovalbumin gene are not transcribed ⬇️

scientific article published on April 29, 1980

Ex Vivo and In Vivo Adenovirus-Mediated Gene Therapy Strategies Induce a Systemic Anti-Tumor Immune Defence in the B16 Melanoma Model ⬇️

scientific article published on June 1, 1998

Expression of MK6a dominant-negative and C-terminal mutant transgenes in mice has distinct phenotypic consequences in the epidermis and hair follicle

scientific article published on October 1999

Expression of a dominant-negative type II transforming growth factor beta (TGF-beta) receptor in the epidermis of transgenic mice blocks TGF-beta-mediated growth inhibition

scientific article

Expression of a p53 mutant in the epidermis of transgenic mice accelerates chemical carcinogenesis ⬇️

scientific article published on July 9, 1998

Expression of keratin genes in mouse epidermis and normal and malignantly transformed epidermal cells in culture.

scientific article published in July 1983

Expression of murine epidermal differentiation markers is tightly regulated by restricted extracellular calcium concentrations in vitro

scientific article

Expression patterns of loricrin in various species and tissues

scientific article

Expression patterns of loricrin in various species and tissues

article

Focal activation of a mutant allele defines the role of stem cells in mosaic skin disorders

scientific article

Functional analysis of activins during mammalian development.

scientific article published on March 1995

Fuz controls the morphogenesis and differentiation of hair follicles through the formation of primary cilia

scientific journal article

Gain-of-function mutant p53 but not p53 deletion promotes head and neck cancer progression in response to oncogenic K-ras.

scientific article published on 26 September 2011

Generation of Functional Multipotent Keratinocytes from Mouse Induced Pluripotent Stem Cells ⬇️

scientific article published on January 1, 2013

Genes involved in stem cell fate decisions and commitment to differentiation play a role in skin disease

scientific article published in September 2004

Genetic disorders of keratin: are scarring alopecias a sub-set?

scientific article published on July 1994

Genetic manipulation of keratinocyte stem cells with lentiviral vectors

scientific article published on 01 January 2013

Genetic pathways required for epidermal morphogenesis

scientific article

Genetically engineered mouse models for skin research: taking the next step

scientific article published on 03 June 2008

Hair follicle companion layer: reacquainting an old friend

scientific article published on 01 May 1995

Harnessing the Power of Regenerative Therapy for Vitiligo and Alopecia Areata

scientific article published on 10 June 2019

Hedgehog in Wnterland

scientific article published on September 2008

Heterogeneous initiation regions for transcription of the chicken ovomucoid gene ⬇️

scientific article published on September 25, 1982

High-efficiency RNA-based reprogramming of human primary fibroblasts

scientific article published on 21 February 2018

Horizontal basal cells are multipotent progenitors in normal and injured adult olfactory epithelium

scientific article

Hot spot mutations in keratin 2e suggest a correlation between genotype and phenotype in patients with ichthyosis bullosa of Siemens

scientific article

Human keratin-1.bcl-2 transgenic mice aberrantly express keratin 6, exhibit reduced sensitivity to keratinocyte cell death induction, and are susceptible to skin tumor formation.

scientific article published in February 1998

Hyperplasia, hyperkeratosis and benign tumor production in transgenic mice by a targeted v-fos oncogene suggest a role for fos in epidermal differentiation and neoplasia

scientific article published on August 1, 1993

IKKalpha is a p63 transcriptional target involved in the pathogenesis of ectodermal dysplasias

scientific article

Identification of a Calcium-Inducible, Epidermal-Specific Regulatory Element in the 3'-Flanking Region of the Human Keratin 1 Gene ⬇️

scientific article published on October 1, 1993

Identification of a novel mutation in keratin 1 in a family with epidermolytic hyperkeratosis

scientific article published on 01 February 2000

Identification of potential ovomucoid mRNA precursors in chick oviduct nuclei ⬇️

scientific article published on March 22, 1979

Identification of sporadic mutations in the helix initiation motif of keratin 6 in two pachyonychia congenita patients: further evidence for a mutational hot spot

scientific article published on 01 April 1999

IkappaB kinase-alpha acts in the epidermis to control skeletal and craniofacial morphogenesis

scientific article published on April 2004

Immunoelectron microscopic analysis of cornified cell envelope formation in normal and psoriatic epidermis

article

Immunological gene therapy approaches for malignant melanoma. 1. Tumor-immunological background.

scientific article published on January 1997

Immunological gene therapy approaches for malignant melanoma. 2. Preclinical studies and clinical strategies

scientific article

In utero activation of K5.CrePR1 induces gene deletion

scientific article published in February 2002

Induced pluripotent stem cells in dermatology: potentials, advances, and limitations

scientific article

Inducible activation of oncogenic K-ras results in tumor formation in the oral cavity.

scientific article

Inducible mouse models for inherited skin diseases: implications for skin gene therapy

scientific article

Induction of epidermal hyperplasia, hyperkeratosis, and papillomas in transgenic mice by a targeted v‐Ha‐ras oncogene ⬇️

scientific article published on January 1, 1993

Inhibition of melanoma growth by adenoviral-mediated HSV thymidine kinase gene transfer in vivo

scientific article published in March 1995

Inhibition of retinoid signaling in transgenic mice alters lipid processing and disrupts epidermal barrier function

scientific article published in June 1997

Inhibition of skin development by overexpression of transforming growth factor beta 1 in the epidermis of transgenic mice

scientific article

Integration of Notch 1 and calcineurin/NFAT signaling pathways in keratinocyte growth and differentiation control.

scientific article published in May 2005

Interaction between the TP63 and SHH pathways is an important determinant of epidermal homeostasis

scientific article published on 17 May 2013

International Research Symposium on Ankyloblepharon-Ectodermal Defects-Cleft Lip/Palate (AEC) syndrome.

scientific article published in September 2009

Isolating RNA from precursor and mature melanocytes from human vitiligo and normal skin using laser capture microdissection

scientific article

Isolation and characterization of squamous cell carcinoma-derived stem-like cells: role in tumor formation.

scientific article published on 26 September 2013

Isolation of complementary DNA for bullous pemphigoid antigen by use of patients' autoantibodies

scholarly article

K14-GLp65 transactivator induces transgene expression in embryonic epidermis

scientific article published on 01 February 2002

Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation

scientific article (publication date: November 2003)

Keratin 6 is not essential for mammary gland development

scientific article

Keratin expression in mouse epidermal tumors

scientific article published on January 1989

Keratin gene expression in mouse epidermis and cultured epidermal cells ⬇️

scientific article published on February 1, 1983

Keratin gene expression in mouse skin tumors and in mouse skin treated with 12-O-tetradecanoylphorbol-13-acetate

scientific article

Keratins 1 and 10 or homologues as regular constituents of inner root sheath and cuticle cells in the human hair follicle

scientific article published on August 1, 1990

Langerhans cells in the TGF beta 1 null mouse

scientific article published on 01 January 1997

Lce1 Family Members Are Nrf2-Target Genes that Are Induced to Compensate for the Loss of Loricrin

scientific article published on 07 May 2016

Loricrin Confers Photoprotective Function against UVB in Corneocytes

scientific article published on 19 June 2018

Loricrin expression is coordinated with other epidermal proteins and the appearance of lipid lamellar granules in development

scientific article published on March 1995

Loricrin immunoreactivity in human skin: localization to specific granules (L-granules) in acrosyringia

scientific article (publication date: 1993)

Loricrin: Past, Present, and Future

scientific article published on 25 March 2020

MELANOCYTE PRECURSORS IN THE HAIR FOLLICLE BULGE OF REPIGMENTED VITILIGO SKIN ARE CONTROLLED BY RHO-GTPase, KCTD10 AND CTNNB1 SIGNALING

scientific article published on 12 August 2020

Mechanisms regulating epithelial stratification

scientific article published on January 2007

Melanoma-initiating cells: a compass needed.

scientific article published on 14 August 2009

Mice expressing a mutant Krt75 (K6hf) allele develop hair and nail defects resembling pachyonychia congenita

scientific article published on 13 September 2007

MicroRNA-203 represses selection and expansion of oncogenic Hras transformed tumor initiating cells

scientific article

Mimicking Hair Disorders by Genetic Manipulation of Organ-Cultured Human Hair Follicles ⬇️

scientific article published on October 1, 2012

Molecular cloning of mouse epidermal cystatin A and detection of regulated expression in differentiation and tumorigenesis

scientific article

Montagna Symposium 2011: 60th Anniversary--Advances in Science and Medicine Catalyzed by Pioneering Skin Research.

scientific article

Mouse differentiation-specific keratins 1 and 10 require a preexisting keratin scaffold to form a filament network ⬇️

scientific article published on March 1, 1993

Mouse models in preclinical studies for pachyonychia congenita

scientific article

Multiple defects and perinatal death in mice deficient in follistatin

scientific article published on March 1995

Multistage epidermal carcinogenesis in transgenic mice: cooperativity and paradox

scientific article published on April 1, 1996

Multistage skin carcinogenesis in transgenic mice.

scientific article published on July 1995

Mutations in Recessive Congenital Ichthyoses Illuminate the Origin and Functions of the Corneocyte Lipid Envelope

scientific article published on 22 November 2018

Mutations in the 1A domain of keratin 9 in patients with epidermolytic palmoplantar keratoderma

scientific article published on 01 March 1995

Mutations in the rod domain of keratin 2e in patients with ichthyosis bullosa of Siemens ⬇️

scientific article published on August 1, 1994

Mutations in the rod domains of keratins 1 and 10 in epidermolytic hyperkeratosis

scientific article published on August 21, 1992

Myc, Aurora Kinase A, and mutant p53(R172H) co-operate in a mouse model of metastatic skin carcinoma.

scientific article

NAD(P)H:quinone oxidoreductase 1 deficiency and increased susceptibility to 7,12-dimethylbenz[a]-anthracene-induced carcinogenesis in mouse skin

scientific article published in August 2001

NAD(P)H:quinone oxidoreductase 1 deficiency increases susceptibility to benzo(a)pyrene-induced mouse skin carcinogenesis

scientific article published on 01 November 2000

NRF2 Augments Epidermal Antioxidant Defenses and Promotes Atopy

scientific article published on 20 July 2020

Narrow Band Ultraviolet B Treatment for Human Vitiligo Is Associated with Proliferation, Migration, and Differentiation of Melanocyte Precursors

scientific article

Nrf2 links epidermal barrier function with antioxidant defense

scientific article

Oct-4: the almighty POUripotent regulator?

scientific article published on February 2007

Organization of a type I keratin gene. Evidence for evolution of intermediate filaments from a common ancestral gene

scientific article published in May 1985

Osteoblasts Derived from Induced Pluripotent Stem Cells form Calcified Structures in Scaffolds Both In Vitro and In Vivo ⬇️

scientific article published on February 1, 2011

P63 deficiency: a failure of lineage commitment or stem cell maintenance?

scientific article

Paradoxical tumor inhibitory effect of p53 loss in transgenic mice expressing epidermal-targeted v-rasHa, v-fos, or human transforming growth factor alpha.

scientific article published in October 1996

Plasma membrane assays and three-compartment image cytometry for high content screening

scientific article published on February 2007

Prenatal diagnosis for keratin mutations to exclude transmission of epidermolytic hyperkeratosis ⬇️

scientific article published on 01 August 1998

Prenatal diagnosis of epidermolytic hyperkeratosis by direct gene sequencing

scientific article

Proteomic Analysis of Loricrin Knockout Mouse Epidermis

scientific article published on 15 July 2016

Proto-oncogene expression during two-stage carcinogenesis in mouse skin

scientific article

Quasi-normal cornified cell envelopes in loricrin knockout mice imply the existence of a loricrin backup system

scientific article published in January 2002

Reactivation of developmentally expressed p63 isoforms predisposes to tumor development and progression.

scientific article

Regulated cutaneous gene delivery: the skin as a bioreactor

scientific article

Regulated expression of differentiation-associated keratins in cultured epidermal cells detected by monospecific antibodies to unique peptides of mouse epidermal keratins

scientific article published on January 1987

Regulated synthesis of low-molecular-weight antigens in keratinocyte cell cultures

scientific article published in October 1986

Regulation of Head and Neck Squamous Cancer Stem Cells by PI3K and SOX2.

scientific article published on 15 September 2016

Relationship between the expression of differentiation-specific keratins 1 and 10 and cell proliferation in epidermal tumors

scientific article published on January 1992

Repigmentation of Human Vitiligo Skin by NBUVB Is Controlled by Transcription of GLI1 and Activation of the β-Catenin Pathway in the Hair Follicle Bulge Stem Cells

scientific article

Report of the 10th Annual International Pachyonychia Congenita Consortium Meeting

scientific article

Retinoic Acid Suppression of loricrin Expression in Reconstituted Human Skin Cultured at the Liquid-Air Interface

scientific article published on 01 June 1994

Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models.

scientific article

SKI knockdown inhibits human melanoma tumor growth in vivo

scientific article published on 01 December 2009

Shared gene expression patterns in mesenchymal progenitors derived from lung and epidermis in pulmonary arterial hypertension: identifying key pathways in pulmonary vascular disease.

scientific article published on December 2016

Side Population Cells from Human Melanoma Tumors Reveal Diverse Mechanisms for Chemoresistance ⬇️

scientific article published on May 24, 2012

Signal transduction for proliferation and differentiation in keratinocytes

scientific article published on January 1988

Sorting out the p63 signaling network

scientific article

Structural Features of Epidermal Keratin Filaments Reassembled in Vitro ⬇️

scientific article published on 01 July 1983

Structural and functional implications of amino acid sequences of keratin intermediate filament subunits

scientific article published on January 1985

Structure and expression of a chicken gene coding for U1 RNA ⬇️

scientific article published on March 1, 1981

Structure of a gene for the human epidermal 67-kDa keratin

scientific article

Studying immunotherapy resistance in a melanoma autologous humanized mouse xenograft

scientific article published on 21 October 2020

Suppressing AP1 factor signaling in the suprabasal epidermis produces a keratoderma phenotype

scientific article

Synthetic peptides corresponding to keratin subunits elicit highly specific antibodies ⬇️

scientific article published on July 10, 1984

TAp63alpha induces AP-2gamma as an early event in epidermal morphogenesis

scientific article published in December 2005

TGF alpha and v-fos cooperation in transgenic mouse epidermis induces aberrant keratinocyte differentiation and stable, autonomous papillomas

scientific article published on 01 January 1995

Targeted ablation of Arnt in mouse epidermis results in profound defects in desquamation and epidermal barrier function

scientific article published on 14 November 2006

Targeted expression of c-Myc in the epidermis alters normal proliferation, differentiation and UV-B induced apoptosis

scientific article published on 01 August 1999

Targeting gene expression to the epidermis of transgenic mice: potential applications to genetic skin disorders

scientific article published on November 1990

The Grainyhead-like epithelial transactivator Get-1/Grhl3 regulates epidermal terminal differentiation and interacts functionally with LMO4

scientific journal article

The KEAP1/NRF2 Signaling Pathway in Keratinization

scientific article published on 14 August 2020

The Ovalbumin Gene: Organization, Structure, Transcription, and Regulation

scientific article published on January 1, 1979

The complete cDNA and deduced amino acid sequence of a type II mouse epidermal keratin of 60,000 Da: analysis of sequence differences between type I and type II keratins ⬇️

scientific article published on September 1, 1984

The complete sequence of the human intermediate filament chain keratin 10. Subdomainal divisions and model for folding of end domain sequences

scientific article

The effect of c-myc on stem cell fate influences skin tumor phenotype

scientific article

The epidermis as a bioreactor: topically regulated cutaneous delivery into the circulation

scientific article

The gene for mouse epidermal filaggrin precursor. Its partial characterization, expression, and sequence of a repeating filaggrin unit

scientific article

The malignant conversion step of mouse skin carcinogenesis

scientific article

The molecular biology of intermediate filaments

scientific article published on September 1985

The mouse keratin 6 isoforms are differentially expressed in the hair follicle, footpad, tongue and activated epidermis

scientific article published on 01 October 1999

The ovalbumin gene: transcriptional regulation by estrogen

scientific article published on January 1979

The proximal promoter of the mouse loricrin gene contains a functional AP-1 element and directs keratinocyte-specific but not differentiation-specific expression

scientific article published on May 1995

The role of keratins in epidermal development and homeostasis--going beyond the obvious

scientific article published in November 2004

The role of p63 in development and differentiation of the epidermis

scientific article (publication date: February 2004)

The use of cDNA clones and monospecific antibodies as probes to monitor keratin gene expression

scientific article published on 01 January 1985

The v-ras oncogene inhibits the expression of differentiation markers and facilitates expression of cytokeratins 8 and 18 in mouse keratinocytes ⬇️

scientific article published on January 1, 1990

Therapeutic siRNAs for dominant genetic skin disorders including pachyonychia congenita.

scientific article published on 20 May 2008

Tracing the Equilibrium Phase of Cancer Immunoediting in Epidermal Neoplasms via Longitudinal Intravital Imaging

scientific article published on 19 September 2019

Transcription of structural and intervening sequences in the ovalbumin gene and identification of potential ovalbumin mRNA precursors

scientific article published on October 1, 1978

Transcription of the human loricrin gene in vitro is induced by calcium and cell density and suppressed by retinoic acid

scientific article published on 01 April 1991

Transcriptional control of high molecular weight keratin gene expression in multistage mouse skin carcinogenesis

scientific article published on June 1988

Transcriptional regulation of bcl-2 mediated by the sonic hedgehog signaling pathway through gli-1.

scientific article published on 10 October 2003

Transduction of a preselected population of human epidermal stem cells: consequences for gene therapy

scientific article

Transfection of the EJ rasHa gene into keratinocytes derived from carcinogen-induced mouse papillomas causes malignant progression

scientific article published on September 1986

Transgenic Models of Skin Diseases ⬇️

scientific article published on November 1, 1993

Transgenic coexpression of v-Ha-ras and transforming growth factor alpha increases epidermal hyperproliferation and tumorigenesis and predisposes to malignant conversion via endogenous c-Ha-ras activation.

scientific article published in March 2000

Transgenic mice expressing a mutant form of loricrin reveal the molecular basis of the skin diseases, Vohwinkel syndrome and progressive symmetric erythrokeratoderma

scientific article

Transgenic mice expressing targeted HPV-18 E6 and E7 oncogenes in the epidermis develop verrucous lesions and spontaneous, rasHa-activated papillomas ⬇️

scientific article published on 01 June 1994

Transgenic mouse models provide new insights into the role of p63 in epidermal development

scientific article published on April 2004

Treasure or artifact: a decade of p63 research speaks for itself.

scientific article published on January 2010

Trends in Regenerative Medicine: Repigmentation in Vitiligo Through Melanocyte Stem Cell Mobilization

scientific article

Use of laser capture microscopy in the analysis of mouse models of human diseases

scientific article published on 01 January 2002

WNT4 is a key regulator of normal postnatal uterine development and progesterone signaling during embryo implantation and decidualization in the mouse.

scientific article

XactMice: humanizing mouse bone marrow enables microenvironment reconstitution in a patient-derived xenograft model of head and neck cancer

scientific article

Yin-yang 1 negatively regulates the differentiation-specific transcription of mouse loricrin gene in undifferentiated keratinocytes

scientific article published on 01 December 2004

c-Myc and epidermal stem cell fate determination

scientific article published on May 2004

p53 prevents progression of nevi to melanoma predominantly through cell cycle regulation

scientific article published on December 2010

p63 and epithelial appendage development

scientific article

p63 directly induces expression of Alox12, a regulator of epidermal barrier formation

scientific article

p63 heterozygous mutant mice are not prone to spontaneous or chemically induced tumors.

scholarly article

p63 induces key target genes required for epidermal morphogenesis

scholarly article

p63 is the molecular switch for initiation of an epithelial stratification program

scientific journal article

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