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List of works by Matthew L Freedman

A Distinct Chromatin State Drives Therapeutic Resistance in Invasive Lobular Breast Cancer

scientific article published in 2022

A Large Study of Androgen Receptor Germline Variants and Their Relation to Sex Hormone Levels and Prostate Cancer Risk. Results from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium.

scientific article published in July 2010

A common 8q24 variant in prostate and breast cancer from a large nested case-control study

scientific article

A comprehensive analysis of common IGF1, IGFBP1 and IGFBP3 genetic variation with prospective IGF-I and IGFBP-3 blood levels and prostate cancer risk among Caucasians

scientific article

A comprehensive analysis of the androgen receptor gene and risk of breast cancer: results from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3).

scientific article published on January 2006

A large study of androgen receptor germline variants and their relation to sex hormone levels and prostate cancer risk. Results from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium

scientific article

A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer

scientific article published on 14 September 2014

A rare variant of African ancestry activates 8q24 lncRNA hub by modulating cancer associated enhancer

scientific article published on 17 July 2020

A transcriptome-wide association study of high-grade serous epithelial ovarian cancer identifies new susceptibility genes and splice variants

scientific article published on 01 May 2019

Admixture mapping identifies 8q24 as a prostate cancer risk locus in African-American men.

scholarly article

Admixture mapping of 15,280 African Americans identifies obesity susceptibility loci on chromosomes 5 and X.

scientific article published on 22 May 2009

An admixture scan in 1,484 African American women with breast cancer

scientific article published on 20 October 2009

Analysis of the 10q11 cancer risk locus implicates MSMB and NCOA4 in human prostate tumorigenesis

scientific article

Aspirin use, 8q24 single nucleotide polymorphism rs6983267, and colorectal cancer according to CTNNB1 alterations

scientific article

Assessing the impact of population stratification on genetic association studies

scientific article

Associations of prostate cancer risk variants with disease aggressiveness: results of the NCI-SPORE Genetics Working Group analysis of 18,343 cases

scientific article

Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation

scientific article published on 7 April 2016

Author Correction: Large-scale transcriptome-wide association study identifies new prostate cancer risk regions

scientific article published in Nature Communications

Cell-type-specific enrichment of risk-associated regulatory elements at ovarian cancer susceptibility loci

scientific article published on 24 March 2015

Circulating colony stimulating factor-1 and breast cancer risk

scientific article

Cis-eQTL analysis and functional validation of candidate susceptibility genes for high-grade serous ovarian cancer

scientific article published on 22 September 2015

Common genetic variation in IGF1 and prostate cancer risk in the Multiethnic Cohort.

scientific article published in January 2006

Common genetic variation in IGF1, IGFBP-1, and IGFBP-3 in relation to mammographic density: a cross-sectional study

scientific article published on January 2007

Common variants at the CHEK2 gene locus and risk of epithelial ovarian cancer

scientific article

Correction: Evaluation of significant genome-wide association studies risk-SNPs in young breast cancer patients

scientific article published on 12 March 2020

Corrigendum re “Genetic Variants Related to Longer Telomere Length are Associated with Increased Risk of Renal Cell Carcinoma” [Eur Urol 2017;72:747–54]

scholarly article published in European Urology

Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations

scientific article

Demonstrating stratification in a European American population

Drug-Induced Epigenomic Plasticity Reprograms Circadian Rhythm Regulation to Drive Prostate Cancer toward Androgen Independence

scientific article published in 2022

EZH2 inhibition activates a dsRNA-STING-interferon stress axis that potentiates response to PD-1 checkpoint blockade in prostate cancer

scientific article published on 22 March 2021

Enrichment of putative PAX8 target genes at serous epithelial ovarian cancer susceptibility loci

scientific article published on 19 January 2017

Evaluation of 8q24 and 17q risk loci and prostate cancer mortality

scientific article

Evaluation of computer-aided detection and diagnosis systems

scientific article

Evaluation of significant genome-wide association studies risk - SNPs in young breast cancer patients.

scientific article

Evaluation of the 8q24 prostate cancer risk locus and MYC expression.

scientific article

Extensive androgen receptor enhancer heterogeneity in primary prostate cancers underlies transcriptional diversity and metastatic potential

scientific article published in 2022

Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants.

scientific article published on 11 June 2018

Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus

scientific article published on 7 September 2016

Genetic Variants Related to Longer Telomere Length are Associated with Increased Risk of Renal Cell Carcinoma ⬇️

scientific article published on 7 August 2017

Genetic and functional analyses implicate the NUDT11, HNF1B, and SLC22A3 genes in prostate cancer pathogenesis

scientific article published on 22 June 2012

Genetic variation in the HSD17B1 gene and risk of prostate cancer

scientific article

Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types

scientific article published in September 2016

Genome-wide association study identifies multiple risk loci for renal cell carcinoma ⬇️

scientific article

Genome-wide association study of prostate cancer mortality

scientific article

Haplotype analysis of the HSD17B1 gene and risk of breast cancer: a comprehensive approach to multicenter analyses of prospective cohort studies

scientific article published in February 2006

Igf-I genetic variation and breast cancer: the multiethnic cohort

scientific article

Integration of multiethnic fine-mapping and genomic annotation to prioritize candidate functional SNPs at prostate cancer susceptibility regions

scientific article

Large-scale transcriptome-wide association study identifies new prostate cancer risk regions

scientific article published in Nature Communications

Modeling and E-M estimation of haplotype-specific relative risks from genotype data for a case-control study of unrelated individuals

scientific article

Multiple regions within 8q24 independently affect risk for prostate cancer

scientific article published on April 2007

National Cancer Institute Prostate Cancer Genetics Workshop

scientific article

Network-Based Integration of GWAS and Gene Expression Identifies a HOX-Centric Network Associated with Serous Ovarian Cancer Risk

scientific article

Patterns of structural variation define prostate cancer across disease states

scientific article published in 2022

Prostate cancer reactivates developmental epigenomic programs during metastatic progression

scientific article published on 20 July 2020

Quality assurance and training procedures for computer-aided detection and diagnosis systems in clinical use

scientific article

Reprogramming of the FOXA1 cistrome in treatment-emergent neuroendocrine prostate cancer

scientific article published on 30 March 2021

Role of Genetic Testing for Inherited Prostate Cancer Risk: Philadelphia Prostate Cancer Consensus Conference 2017.

scientific article

STrengthening the REporting of Genetic Association Studies (STREGA)-an extension of the STROBE statement

article

STrengthening the REporting of Genetic Association Studies (STREGA): An Extension of the STROBE Statement

article

STrengthening the REporting of Genetic Association Studies (STREGA): an extension of the STROBE statement

scientific article

STrengthening the REporting of Genetic Association studies (STREGA)--an extension of the STROBE statement

scientific article published on April 2009

STrengthening the REporting of Genetic Association studies (STREGA)—an extension of the STROBE statement

article

Sensitivity of noncommercial computer-aided detection system for mammographic breast cancer detection: pilot clinical trial

scientific article published on 27 February 2004

Sex specific associations in genome wide association analysis of renal cell carcinoma

scientific article published on 23 June 2019

Strengthening the reporting of genetic association studies (STREGA): an extension of the STROBE Statement

article

Strengthening the reporting of genetic association studies (STREGA): an extension of the STROBE statement

article

Strengthening the reporting of genetic association studies (STREGA): an extension of the strengthening the reporting of observational studies in epidemiology (STROBE) statement

scientific article published on 12 February 2009

Subtype heterogeneity and epigenetic convergence in neuroendocrine prostate cancer

scientific article published on 01 October 2021

Systematic evaluation of genetic variation at the androgen receptor locus and risk of prostate cancer in a multiethnic cohort study

scientific article

The androgen receptor cistrome is extensively reprogrammed in human prostate tumorigenesis

scientific article

The influence of obesity-related factors in the etiology of renal cell carcinoma-A mendelian randomization study ⬇️

scientific article published on 03 January 2019

Transferability of tag SNPs in genetic association studies in multiple populations

scientific article published on 22 October 2006

mRNA expression signature of Gleason grade predicts lethal prostate cancer

scientific article published on 2 May 2011

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