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List of works by Tsvee Lapidot

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G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4.

scientific article published on 17 June 2002
How do stem cells find their way home?

scientific article
Osteoclasts degrade endosteal components and promote mobilization of hematopoietic progenitor cells

scientific article published on 21 May 2006
Current understanding of stem cell mobilization: the roles of chemokines, proteolytic enzymes, adhesion molecules, cytokines, and stromal cells

scientific article
HGF, SDF-1, and MMP-9 are involved in stress-induced human CD34+ stem cell recruitment to the liver

scientific article published on July 2003
CD44 and hyaluronic acid cooperate with SDF-1 in the trafficking of human CD34+ stem/progenitor cells to bone marrow

scientific article
Caspase-8 serves both apoptotic and nonapoptotic roles

scientific journal article
Mutual, reciprocal SDF-1/CXCR4 interactions between hematopoietic and bone marrow stromal cells regulate human stem cell migration and development in NOD/SCID chimeric mice

scientific article published on August 2006
Stromal-derived factor-1 promotes the growth, survival, and development of human bone marrow stromal stem cells.

scientific article
Distinct bone marrow blood vessels differentially regulate haematopoiesis.

scientific article published on 13 April 2016
CXCR4 regulates migration and development of human acute myelogenous leukemia stem cells in transplanted NOD/SCID mice

scientific article published on April 2004
Catecholaminergic neurotransmitters regulate migration and repopulation of immature human CD34+ cells through Wnt signaling

scientific article published on 09 September 2007
Chemokine receptor CXCR4-dependent internalization and resecretion of functional chemokine SDF-1 by bone marrow endothelial and stromal cells

scientific article published on 18 September 2005
Age-dependent modulation of vascular niches for haematopoietic stem cells

scientific article published on April 13, 2016
S1P promotes murine progenitor cell egress and mobilization via S1P1-mediated ROS signaling and SDF-1 release

scientific article published on 25 January 2012
A crosstalk between intracellular CXCR7 and CXCR4 involved in rapid CXCL12-triggered integrin activation but not in chemokine-triggered motility of human T lymphocytes and CD34+ cells

scientific article published on 24 July 2008
Overexpression of CXCR4 on human CD34+ progenitors increases their proliferation, migration, and NOD/SCID repopulation

scientific article published on 24 December 2003
Rapid mobilization of hematopoietic progenitors by AMD3100 and catecholamines is mediated by CXCR4-dependent SDF-1 release from bone marrow stromal cells

scientific article
Elevated serum levels of stromal-derived factor-1alpha are associated with increased osteoclast activity and osteolytic bone disease in multiple myeloma patients.

scientific article published on March 2005
p53 Attenuates cancer cell migration and invasion through repression of SDF-1/CXCL12 expression in stromal fibroblasts

scientific article published on November 2006
Monocytes-macrophages that express α-smooth muscle actin preserve primitive hematopoietic cells in the bone marrow

scientific article
CXCL12 secretion by bone marrow stromal cells is dependent on cell contact and mediated by connexin-43 and connexin-45 gap junctions

scientific article
Stem cell mobilization.

scientific article published on January 2003
The multiple roles of osteoclasts in host defense: bone remodeling and hematopoietic stem cell mobilization

scientific article published on January 2007
Atypical PKC-zeta regulates SDF-1-mediated migration and development of human CD34+ progenitor cells

scientific article
Enhanced c-Met activity promotes G-CSF-induced mobilization of hematopoietic progenitor cells via ROS signaling

scientific article published on 28 June 2010
Unique SDF-1-induced activation of human precursor-B ALL cells as a result of altered CXCR4 expression and signaling

scientific article published on 20 November 2003
Reactive oxygen species regulate hematopoietic stem cell self-renewal, migration and development, as well as their bone marrow microenvironment

scientific article published on 26 June 2014
MT1-MMP and RECK are involved in human CD34+ progenitor cell retention, egress, and mobilization

scientific article published on 9 February 2009
The ATM-BID pathway regulates quiescence and survival of haematopoietic stem cells

scientific article published on 25 March 2012
Human CD34(+)CXCR4(-) sorted cells harbor intracellular CXCR4, which can be functionally expressed and provide NOD/SCID repopulation

scientific article published on 01 October 2002
An MTCH2 pathway repressing mitochondria metabolism regulates haematopoietic stem cell fate

scientific journal article
Stem cell regulation via dynamic interactions of the nervous and immune systems with the microenvironment

scientific article
Biology of normal and acute myeloid leukemia stem cells

scientific article
PAR1 signaling regulates the retention and recruitment of EPCR-expressing bone marrow hematopoietic stem cells

scientific article published on 12 October 2015
The brain-bone-blood triad: traffic lights for stem-cell homing and mobilization

scientific article published on January 2010
cAMP-induced PKCzeta activation increases functional CXCR4 expression on human CD34+ hematopoietic progenitors

scientific article
FGF-2 expands murine hematopoietic stem and progenitor cells via proliferation of stromal cells, c-Kit activation, and CXCL12 down-regulation

scientific article
CD45 regulates retention, motility, and numbers of hematopoietic progenitors, and affects osteoclast remodeling of metaphyseal trabecules

scientific article published on 8 September 2008
The Wnt antagonist Dickkopf-1 mobilizes vasculogenic progenitor cells via activation of the bone marrow endosteal stem cell niche

scientific article
Use of lipophilic near-infrared dye in whole-body optical imaging of hematopoietic cell homing

scientific article published in September 2006
B-cell depletion reactivates B lymphopoiesis in the BM and rejuvenates the B lineage in aging

scientific article published on January 12, 2011
Immature leukemic CD34+CXCR4+ cells from CML patients have lower integrin-dependent migration and adhesion in response to the chemokine SDF-1.

scientific article
Pathways Implicated in Stem Cell Migration: The SDF-1/CXCR4 Axis

scientific article published on 01 January 2011
Functional CXCR4-expressing microparticles and SDF-1 correlate with circulating acute myelogenous leukemia cells

scientific article published on 01 November 2006
FGF signaling facilitates postinjury recovery of mouse hematopoietic system.

scientific article
Down-regulation of homeobox genes MEIS1 and HOXA in MLL-rearranged acute leukemia impairs engraftment and reduces proliferation

scientific article
Ex vivo expansion of human adult stem cells capable of primary and secondary hemopoietic reconstitution.

scientific article published in March 2003
Regulation of Hematopoiesis and Osteogenesis by Blood Vessel-Derived Signals

scientific article
Heat shock protein 60 activates cytokine-associated negative regulator suppressor of cytokine signaling 3 in T cells: effects on signaling, chemotaxis, and inflammation

scientific article published on 01 July 2005

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