List of works by Amber L Beitelshees

A Genetic Response Score for Hydrochlorothiazide Use: Insights From Genomics and Metabolomics Integration

scientific article published on 5 July 2016

A PPARα promoter variant impairs ERR-dependent transactivation and decreases mortality after acute coronary ischemia in patients with diabetes

scientific article (publication date: 3 September 2010)

A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response

scientific article

Adrenergic-pathway gene variants influence beta-blocker-related outcomes after acute coronary syndrome in a race-specific manner

scientific article published on 13 June 2012

Alpha-adducin polymorphism associated with increased risk of adverse cardiovascular outcomes: results from GENEtic Substudy of the INternational VErapamil SR-trandolapril STudy (INVEST-GENES).

scientific article published on 20 June 2008

Applying pharmacogenomics to enhance the use of biomarkers for drug effect and drug safety

scientific article published on 27 July 2006

Aromatase gene polymorphisms are associated with survival among patients with cardiovascular disease in a sex-specific manner

scientific article (publication date: 10 December 2010)

Association of branched and aromatic amino acids levels with metabolic syndrome and impaired fasting glucose in hypertensive patients

scientific article published on 9 February 2015

Association of variants in NEDD4L with blood pressure response and adverse cardiovascular outcomes in hypertensive patients treated with thiazide diuretics

scientific article published on April 2013

Blood pressure response to metoprolol and chlorthalidone in European and African Americans with hypertension

scientific article

Blood pressure responses and metabolic effects of hydrochlorothiazide and atenolol

scientific article published on 17 November 2011

Blood pressure signature genes and blood pressure response to thiazide diuretics: results from the PEAR and PEAR-2 studies.

scientific article

CACNA1C gene polymorphisms, cardiovascular disease outcomes, and treatment response

scientific article published on 03 June 2009

CXCL5 gene polymorphisms are related to systemic concentrations and leukocyte production of epithelial neutrophil-activating peptide (ENA-78).

scientific article published on 29 March 2006

CXCL5 polymorphisms are associated with variable blood pressure in cardiovascular disease-free adults

scientific article

Chromosome 9p21 haplotypes and prognosis in white and black patients with coronary artery disease

scientific article

Clopidogrel pharmacogenetics: promising steps towards patient care?

scientific article published on 01 August 2006

Common laboratory methods in pharmacogenomics studies

scientific article published on 01 November 2006

Comparison of office, ambulatory, and home blood pressure antihypertensive response to atenolol and hydrochlorthiazide

scientific article

Correction: Evaluating the extent of reusability of CYP2C19 genotype data among patients genotyped for antiplatelet therapy selection

scientific article published on 03 August 2020

Correlates of serum matrix metalloproteinase-8 (MMP-8) concentrations in nondiabetic subjects without cardiovascular disease.

scientific article published on 20 December 2006

Cost-effectiveness of CYP2C19-guided antiplatelet therapy in patients with acute coronary syndrome and percutaneous coronary intervention informed by real-world data

scientific article published on 11 February 2020

Cost-effectiveness of cytochrome P450 2C19 genotype screening for selection of antiplatelet therapy with clopidogrel or prasugrel

scientific article published on April 2012

Development of Customizable Implementation Guides to Support Clinical Adoption of Pharmacogenomics: Experiences of the Implementing GeNomics In pracTicE (IGNITE) Network

scientific article published on 17 July 2020

Discordance between availability of pharmacogenetics studies and pharmacogenetics-based prescribing information for the top 200 drugs

scientific article published on 07 March 2006

Discordant beta-blocker effects on clinic, ambulatory, resting, and exercise hemodynamics in patients with hypertension

scientific article published on 01 September 2006

Effect of plasma MicroRNA on antihypertensive response to beta blockers in the Pharmacogenomic Evaluation of Antihypertensive Responses (PEAR) studies

scientific article published on 10 February 2019

Effects of genetic variation in H3K79 methylation regulatory genes on clinical blood pressure and blood pressure response to hydrochlorothiazide

scientific article published on 22 March 2012

Epithelial neutrophil-activating peptide (ENA-78), acute coronary syndrome prognosis, and modulatory effect of statins

scientific article

Evaluating the extent of reusability of CYP2C19 genotype data among patients genotyped for antiplatelet therapy selection

scientific article published on 17 July 2020

Evolving research and stakeholder perspectives on pharmacogenomics

scientific article published on September 2011

G protein receptor kinase 4 polymorphisms: β-blocker pharmacogenetics and treatment-related outcomes in hypertension

scientific article

Gene-centric meta-analyses for central adiposity traits in up to 57 412 individuals of European descent confirm known loci and reveal several novel associations

scientific article published on 17 December 2013

Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci

scientific article published on 20 February 2014

Genetic Variants Associated With Uncontrolled Blood Pressure on Thiazide Diuretic/β-Blocker Combination Therapy in the PEAR (Pharmacogenomic Evaluation of Antihypertensive Responses) and INVEST (International Verapamil-SR Trandolapril Study) Trials

scientific article published on 2 November 2017

Genetic variation in PEAR1 is associated with platelet aggregation and cardiovascular outcomes

scientific article published on 07 February 2013

Genetic variation in the beta2 subunit of the voltage-gated calcium channel and pharmacogenetic association with adverse cardiovascular outcomes in the INternational VErapamil SR-Trandolapril STudy GENEtic Substudy (INVEST-GENES).

scientific article

Genome Wide Association Study Identifies the HMGCS2 Locus to be Associated With Chlorthalidone Induced Glucose Increase in Hypertensive Patients.

scientific article published on 9 March 2018

Genome-Wide Association Approach Identified Novel Genetic Predictors of Heart Rate Response to β-Blockers.

scientific article published on 24 February 2018

Genomic association analysis of common variants influencing antihypertensive response to hydrochlorothiazide

scientific article published on 10 June 2013

Hypertension susceptibility loci and blood pressure response to antihypertensives: results from the pharmacogenomic evaluation of antihypertensive responses study

scientific article

Hypertensive APOL1 risk allele carriers demonstrate greater blood pressure reduction with angiotensin receptor blockade compared to low risk carriers

scientific article published on 18 September 2019

Impact of abdominal obesity on incidence of adverse metabolic effects associated with antihypertensive medications

scientific article

Impact of the CYP2C19*17 allele on outcomes in patients receiving genotype-guided antiplatelet therapy after percutaneous coronary intervention

scientific article published on 08 September 2020

Implementation of pharmacogenetics: the University of Maryland Personalized Anti-platelet Pharmacogenetics Program

scientific article

Interaction between the UCP2 -866 G>A polymorphism, diabetes, and beta-blocker use among patients with acute coronary syndromes

scientific article

Is Ticagrelor the Antiplatelet Therapy Panacea? ⬇️

scientific article published on November 15, 2010

Is diabetes mellitus-linked amino acid signature associated with β-blocker-induced impaired fasting glucose?

scientific article

KCNMB1 genotype influences response to verapamil SR and adverse outcomes in the INternational VErapamil SR/Trandolapril STudy (INVEST)

scientific article published on September 2007

KCNQ1 and Long QT Syndrome in 1/45 Amish: The Road from Identification to Implementation of Culturally Appropriate Precision Medicine

scientific article published on 03 November 2020

Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci

scientific article

Leveraging linkage evidence to identify low-frequency and rare variants on 16p13 associated with blood pressure using TOPMed whole genome sequencing data

scientific article published on 22 January 2019

Loci influencing blood pressure identified using a cardiovascular gene-centric array

scientific article published on 8 January 2013

Loci influencing blood pressure identified using a cardiovascular gene-centric array.

scientific article

Multi-site investigation of strategies for the clinical implementation of CYP2D6 genotyping to guide drug prescribing

scientific article published on 21 March 2019

Multisite Investigation of Outcomes With Implementation of CYP2C19 Genotype-Guided Antiplatelet Therapy After Percutaneous Coronary Intervention

scientific article

Multisite Investigation of Strategies for the Implementation of CYP2C19 Genotype-Guided Antiplatelet Therapy.

scientific article published on 26 December 2017

NOS3 polymorphisms are associated with arterial stiffness in children with type 1 diabetes

scientific article published in March 2007

Night blood pressure responses to atenolol and hydrochlorothiazide in black and white patients with essential hypertension

scientific article published on 25 July 2013

Novel plasma biomarker of atenolol-induced hyperglycemia identified through a metabolomics-genomics integrative approach

scientific article published on 13 July 2016

Oxylipid Profile of Low-Dose Aspirin Exposure: A Pharmacometabolomics Study

scientific article published on 26 October 2015

PROX1 gene variant is associated with fasting glucose change after antihypertensive treatment

scientific article published on 09 October 2013

PTPRD gene associated with blood pressure response to atenolol and resistant hypertension

scientific article published on November 2015

Personalised antiplatelet treatment: a RAPIDly moving target

scientific article published on 29 March 2012

Personalized antiplatelet and anticoagulation therapy: applications and significance of pharmacogenomics

scientific article

Pharmacodynamic Effects of Low-Dose Pioglitazone in Patients with the Metabolic Syndrome without Diabetes Mellitus

scientific article published on 29 January 2016

Pharmacogenomic Genome-Wide Meta-Analysis of Blood Pressure Response to β-Blockers in Hypertensive African Americans

scientific article published on 4 January 2016

Pharmacogenomics of antihypertensive drugs: rationale and design of the Pharmacogenomic Evaluation of Antihypertensive Responses (PEAR) study

scientific article published on March 2009

Pharmacokinetics and CYP2D6 genotypes do not predict metoprolol adverse events or efficacy in hypertension

scientific article published in December 2004

Pharmacometabolomics reveals racial differences in response to atenolol treatment

scientific article

Pharmacotherapy in chronic kidney disease patients presenting with acute coronary syndrome: a scientific statement from the American Heart Association

scientific article

Plasma Renin Activity Is a Predictive Biomarker of Blood Pressure Response in European but not in African Americans With Uncomplicated Hypertension

scientific article published on 01 June 2019

Plasma Renin Activity Predicts Blood Pressure Responses to -Blocker and Thiazide Diuretic as Monotherapy and Add-On Therapy for Hypertension ⬇️

scientific article published on August 19, 2010

Polymorphisms in genes coding for GRK2 and GRK5 and response differences in antihypertensive-treated patients

scientific article

Power to identify a genetic predictor of antihypertensive drug response using different methods to measure blood pressure response

scientific article published on 13 March 2012

Predictors for glucose change in hypertensive participants following short-term treatment with atenolol or hydrochlorothiazide

scientific article

Prescribing Prevalence of Medications With Potential Genotype-Guided Dosing in Pediatric Patients

scientific article published on 01 December 2020

Presence of arachidonoyl-carnitine is associated with adverse cardiometabolic responses in hypertensive patients treated with atenolol

scientific article published on 15 September 2016

Racial differences in patients' potassium concentrations during spironolactone therapy for heart failure

scientific article published in June 2004

Re: Meckley LM, Veenstra DL. Screening for the alpha-adducin Gly460Trp variant in hypertensive patients: a cost-effectiveness analysis. Pharmacogenet Genom 2006; 16:139-147

scientific article published on 01 August 2006

Renin-angiotensin-aldosterone system (RAAS) pharmacogenomics: implications in heart failure management

scientific article published on 20 March 2008

Response to: Heterogeneous Treatment Response by Race Cannot Be Claimed in the Absence of Evidence

scientific article published on 01 February 2020

SGLT2 inhibitors as adjunctive therapy for type 1 diabetes: balancing benefits and risks

scientific article published on 01 October 2019

Serum monocyte chemoattractant protein-1 concentrations associate with diabetes status but not arterial stiffness in children with type 1 diabetes

scientific article

Single nucleotide polymorphism discovery and haplotype analysis of Ca2+-dependent K+ channel beta-1 subunit

scientific article published on April 2007

Sodium-Glucose Cotransporter 2 Inhibitors: A Case Study in Translational Research

scientific article published on 01 June 2019

Sorting nexin 1 loss results in increased oxidative stress and hypertension

scientific article published on 15 April 2020

Sphingolipid Metabolic Pathway Impacts Thiazide Diuretics Blood Pressure Response: Insights From Genomics, Metabolomics, and Lipidomics.

scientific article published on 29 December 2017

Synergistic polymorphisms of beta1 and alpha2C-adrenergic receptors and the influence on left ventricular ejection fraction response to beta-blocker therapy in heart failure

scientific article published on 01 April 2007

Targeted sequencing identifies a missense variant in the BEST3 gene associated with antihypertensive response to hydrochlorothiazide

article

The Pharmacogenomics Research Network Translational Pharmacogenetics Program: overcoming challenges of real-world implementation

scientific article published on 19 March 2013

User-centered design of multi-gene sequencing panel reports for clinicians

scientific article published on 13 July 2016

Using Workflow Modeling to Identify Areas to Improve Genetic Test Processes in the University of Maryland Translational Pharmacogenomics Project

scientific article

Whole Transcriptome Sequencing Analyses Reveal Molecular Markers of Blood Pressure Response to Thiazide Diuretics

scientific article published on 22 November 2017

β2 -Adrenergic Receptor Gene Affects the Heart Rate Response of β-Blockers: Evidence From 3 Clinical Studies

scientific article published on 14 May 2019

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