List of works by John L. Humm

(124)I-huA33 antibody PET of colorectal cancer.

scientific article

11C-Choline Pharmacokinetics in Recurrent Prostate Cancer.

scientific article

11C-choline PET/CT in recurrent prostate cancer: retrospective analysis in a large US patient series

scientific article published on 20 December 2019

124I-huA33 antibody uptake is driven by A33 antigen concentration in tissues from colorectal cancer patients imaged by immuno-PET.

scientific article

18F-FDG PET/CT Is an Immediate Imaging Biomarker of Treatment Success After Liver Metastasis Ablation

scientific article

18F-Fluorocholine PET uptake correlates with pathologic evidence of recurrent tumor after stereotactic radiosurgery for brain metastases

scientific article published on 21 December 2019

18F-fluoromisonidazole predicts evofosfamide uptake in pancreatic tumor model.

scientific article

A Combination of Radiation and the Hypoxia-Activated Prodrug Evofosfamide (TH-302) is Efficacious against a Human Orthotopic Pancreatic Tumor Model.

scientific article published on 21 July 2017

A novel method to localize antibody-targeted cancer deposits intraoperatively using handheld PET beta and gamma probes

scientific article

A phase II study of radioimmunotherapy with intraventricular 131 I-3F8 for medulloblastoma.

scientific article

A recommendation for revised dose calibrator measurement procedures for 89Zr and 124I

scientific article

Accuracy and precision of radioactivity quantification in nuclear medicine images

scientific article published on May 2012

Accuracy and reproducibility of tumor positioning during prolonged and multi-modality animal imaging studies

scientific article published on 30 September 2008

Adaptation, Commissioning, and Evaluation of a 3D Treatment Planning System for High-Resolution Small-Animal Irradiation

scientific article published on 6 May 2015

An Anti-Tumor Immune Response is Evoked By Partial-Volume Single Dose Radiation in Two Murine Models

scientific article published on 18 October 2018

Animal-specific positioning molds for registration of repeat imaging studies: comparative microPET imaging of F18-labeled fluoro-deoxyglucose and fluoro-misonidazole in rodent tumors

scientific article published in January 2006

Antitumour activity of MDV3100 in castration-resistant prostate cancer: a phase 1-2 study

scientific article

Assessing and accounting for the impact of respiratory motion on FDG uptake and viable volume for liver lesions in free-breathing PET using respiration-suspended PET images as reference

scientific article

Assessment of Simplified Methods for Quantification of 18F-FDHT Uptake in Patients with Metastatic Castration-Resistant Prostate Cancer

scientific article published on 08 March 2019

Assessment of regional tumor hypoxia using 18F-fluoromisonidazole and 64Cu(II)-diacetyl-bis(N4-methylthiosemicarbazone) positron emission tomography: Comparative study featuring microPET imaging, Po2 probe measurement, autoradiography, and fluoresce

scientific article published on April 2005

Biodistribution and Dosimetry of Intraventricularly Administered 124I-Omburtamab in Patients with Metastatic Leptomeningeal Tumors

scientific article published on 12 August 2019

Bone marrow dosimetry using 124I-PET.

scientific article

Cell line-dependent differences in uptake and retention of the hypoxia-selective nuclear imaging agent Cu-ATSM.

scientific article published on August 2005

Changes in FDG Tumor Uptake during and after Fractionated Radiation Therapy in a Rodent Tumor Xenograft ⬇️

scientific article published on 01 October 1999

Changes in tumor hypoxia induced by mild temperature hyperthermia as assessed by dual-tracer immunohistochemistry

scientific article

Clinical translation of an ultrasmall inorganic optical-PET imaging nanoparticle probe

scientific article published on 29 October 2014

Comparing the intra-tumoral distribution of Gemcitabine, 5-Fluorouracil, and Capecitabine in a murine model of pancreatic ductal adenocarcinoma

scientific article published on 16 April 2020

Comparison of Helzel and OxyLite systems in the measurements of tumor partial oxygen pressure (pO2).

scientific article published on January 2008

Compartmental intrathecal radioimmunotherapy: results for treatment for metastatic CNS neuroblastoma

scientific article

Copper-64 trastuzumab PET imaging: a reproducibility study

scientific article published on 12 May 2016

Copper-64-diacetyl-bis(N(4)-methylthiosemicarbazone) pharmacokinetics in FaDu xenograft tumors and correlation with microscopic markers of hypoxia.

scientific article

Correction for oral contrast artifacts in CT attenuation-corrected PET images obtained by combined PET/CT.

scientific article published in December 2003

Correlation Between Tumor Metabolism and Semiquantitative Perfusion Magnetic Resonance Imaging Metrics in Non-Small Cell Lung Cancer.

scientific article published on 2 March 2018

Correlation of in vivo and in vitro measures of carbonic anhydrase IX antigen expression in renal masses using antibody 124I-cG250.

scientific article

Corrigendum to "Noninvasive Multimodality Imaging of the Tumor Microenvironment: Registered Dynamic Magnetic Resonance Imaging and Positron Emission Tomography Studies of a Preclinical Tumor Model of Tumor Hypoxia" [Neoplasia 11 (2009) 247-259]

scientific article published on December 2016

Deep-inspiration breath-hold PET/CT of the thorax.

scientific article published in January 2007

Deep-inspiration breath-hold PET/CT: clinical findings with a new technique for detection and characterization of thoracic lesions.

scientific article published in May 2007

Dependence of FDG uptake on tumor microenvironment.

scientific article

Detection of hypoxia in microscopic tumors using 131I-labeled iodo-azomycin galactopyranoside (131I-IAZGP) digital autoradiography.

scientific article

Differential Metabolism and Pharmacokinetics of ?-[1-11C]-Methionine and 2-[18F] Fluoro-2-deoxy-?-glucose (FDG) in Androgen Independent Prostate Cancer ⬇️

scientific article published on 01 May 1999

Distribution of Gemcitabine Is Nearly Homogenous in Two Orthotopic Murine Models of Pancreatic Cancer

scientific article

EMBR-03. TREATMENT OF EMBRYONAL TUMOR WITH MULTILAYERED ROSETTES (ETMR) WITH TARGETED RADIOIMMUNOTHERAPY

EPEN-04. RECURRENT EPENDYMOMA: ROLE OF INTRAVENTRICULAR TARGETED RADIOIMMUNOTHERAPY

Effect of motion on tracer activity determination in CT attenuation corrected PET images: a lung phantom study

scientific article published in July 2005

Effect of respiratory gating on quantifying PET images of lung cancer.

scientific article published in July 2002

Evaluation of a compartmental model for estimating tumor hypoxia via FMISO dynamic PET imaging.

scientific article published on 6 May 2009

Evaluation of different methods of 18F-FDG-PET target volume delineation in the radiotherapy of head and neck cancer

scientific article published in October 2008

Evaluation of the tumor registration error in biopsy procedures performed under real-time PET/CT guidance.

scientific article

F-18 FDG PET/CT for monitoring of ipilimumab therapy in patients with metastatic melanoma

scientific article published on 09 November 2018

Feasibility and predictability of perioperative PET and estrogen receptor ligand in patients with invasive breast cancer

scientific article published on 22 August 2013

Feasibility of 18F-Fluoromisonidazole Kinetic Modeling in Head and Neck Cancer Using Shortened Acquisition Times

scientific article

Feasibility of ex vivo FDG PET of the colon.

scientific article published on July 2009

Feasibility of in situ, high-resolution correlation of tracer uptake with histopathology by quantitative autoradiography of biopsy specimens obtained under 18F-FDG PET/CT guidance.

scientific article published on 26 February 2015

High 18F-FDG uptake in microscopic peritoneal tumors requires physiologic hypoxia

scientific article

How to assess background activity: introducing a histogram-based analysis as a first step for accurate one-step PET quantification.

scientific article published on March 2014

Hypoxia imaging. Guest editorial.

scientific article published in March 2015

IMMU-05. SAFETY AND EFFICACY OF INTRAVENTRICULAR I-LABELED MONOCLONAL ANTIBODY 8H9 TARGETING THE SURFACE GLYCOPROTEIN B7-H3

Image deconvolution in digital autoradiography: a preliminary study

scientific article

Image-guided PO2 probe measurements correlated with parametric images derived from 18F-fluoromisonidazole small-animal PET data in rats

scientific article

Imaging Patients with Metastatic Castration-Resistant Prostate Cancer Using 89Zr-DFO-MSTP2109A Anti-STEAP1 Antibody

scientific article published on 03 May 2019

In Reply to Pareek.

scientific article published in February 2017

In Vitro and In Vivo Comparison of Gemcitabine and the Gemcitabine Analog 1-(2'-deoxy-2'-fluoroarabinofuranosyl) Cytosine (FAC) in Human Orthotopic and Genetically Modified Mouse Pancreatic Cancer Models.

scientific article published on 27 March 2017

In vivo characterization of a reporter gene system for imaging hypoxia-induced gene expression

scientific article

Initial performance studies of a wearable brain positron emission tomography camera based on autonomous thin-film digital Geiger avalanche photodiode arrays.

scientific article

Inter-operator variability in compartmental kinetic analysis of 18F-fluoromisonidazole dynamic PET.

scientific article published on 12 January 2018

IntraOmmaya compartmental radioimmunotherapy using 131I-omburtamab-pharmacokinetic modeling to optimize therapeutic index

scientific article published on 13 October 2020

Iodination of annexin V for imaging apoptosis.

scientific article

Iodine-124-labeled iodo-azomycin-galactoside imaging of tumor hypoxia in mice with serial microPET scanning.

scientific article published on 2 October 2003

Low incidence of radionecrosis in children treated with conventional radiation therapy and intrathecal radioimmunotherapy

scientific article published on 06 May 2015

MEDU-04. A PHASE II STUDY OF RADIOIMMUNOTHERAPY WITH INTRAVENTRICULAR 131I-3F8 FOR MEDULLOBLASTOMA.

scientific article

Measured dose rate constant from oncology patients administered 18F for positron emission tomography

scientific article published on 01 October 2012

Measurement of lung tumor motion using respiration-correlated CT.

scientific article published in November 2004

Measurements of tumor tissue oxygen tension using a time-resolved luminescence-based optical oxylite probe: comparison with a paired survival assay

scientific article published in August 2002

Modeling acute and chronic hypoxia using serial images of F18-FMISO PET.

scientific article published on October 2009

Monitoring early response to chemoradiotherapy with 18F-FMISO dynamic PET in head and neck cancer

scientific article

Multiparametric Imaging of Tumor Hypoxia and Perfusion with 18F-Fluoromisonidazole Dynamic PET in Head and Neck Cancer

scientific article

NCOG-16. A PILOT STUDY OF COGNITIVE FUNCTIONS, AND AMYLOID IMAGING IN GLIOMA PATIENTS

Non-invasive imaging prediction of tumor hypoxia: a novel developed and externally validated CT and FDG-PET-based radiomic signatures

scientific article published on 30 October 2020

Noninvasive assessment of tumor microenvironment using dynamic contrast-enhanced magnetic resonance imaging and 18F-fluoromisonidazole positron emission tomography imaging in neck nodal metastases.

scientific article

Noninvasive multimodality imaging of the tumor microenvironment: registered dynamic magnetic resonance imaging and positron emission tomography studies of a preclinical tumor model of tumor hypoxia.

scientific article published on March 2009

On autoradiographic studies comparing the distributions of 18F- and 14C-labeled compounds in tumor tissue specimens ⬇️

scientific article published on November 11, 2010

Overcoming Barriers to Radiopharmaceutical Therapy: An Overview from the NRG-NCI Working Group on Dosimetry of Radiopharmaceutical Therapy (RPT)

scientific article published on 10 December 2020

PARP1-Targeted Radiotherapy in Mouse Models of Glioblastoma.

scientific article published on 23 March 2018

PDCT-04. SAFETY AND EFFICACY OF INTRAVENTRICULAR I-LABELED MONOCLONAL ANTIBODY 8H9 TARGETING THE SURFACE GLYCOPROTEIN B7-H3 IN PATIENTS WITH CNS/LM DISEASE

scientific article published on 06 November 2017

PET of hypoxia: current and future perspectives

scientific article published on 12 July 2012

PET performance measurements for an LSO-based combined PET/CT scanner using the National Electrical Manufacturers Association NU 2-2001 standard.

scientific article published in May 2004

PET quantification with a histogram derived total activity metric: superior quantitative consistency compared to total lesion glycolysis with absolute or relative SUV thresholds in phantoms and lung cancer patients

scientific article

PET-based compartmental modeling of (124)I-A33 antibody: quantitative characterization of patient-specific tumor targeting in colorectal cancer

scientific article published on 21 July 2015

PET-based radiation dosimetry in man of 18F-fluorodihydrotestosterone, a new radiotracer for imaging prostate cancer

scientific article published in November 2004

PET/CT in non-small-cell lung cancer: value of respiratory-gated PET.

scientific article published in May 2005

PETSTEP: Generation of synthetic PET lesions for fast evaluation of segmentation methods.

scientific article published on 27 August 2015

Pharmacokinetic Analysis of Dynamic 18F-Fluoromisonidazole PET Data in Non-Small Cell Lung Cancer

scientific article

Pharmacokinetic Assessment of 18F-(2S,4R)-4-Fluoroglutamine in Patients with Cancer

scientific article published on 10 October 2019

Pharmacokinetic analysis of hypoxia (18)F-fluoromisonidazole dynamic PET in head and neck cancer

scientific article

Pharmacokinetic assessment of the uptake of 16beta-18F-fluoro-5alpha-dihydrotestosterone (FDHT) in prostate tumors as measured by PET.

scientific article

Pharmacokinetics and Biodistribution of a [89Zr]Zr-DFO-MSTP2109A Anti-STEAP1 Antibody in Metastatic Castration-Resistant Prostate Cancer Patients

scientific article published on 31 May 2019

Phase I pharmacokinetic and biodistribution study with escalating doses of ²²³Ra-dichloride in men with castration-resistant metastatic prostate cancer.

scientific article

Phase I study of targeted radioimmunotherapy for leptomeningeal cancers using intra-Ommaya 131-I-3F8.

scientific article

Pilot study of PET imaging of 124I-iodoazomycin galactopyranoside (IAZGP), a putative hypoxia imaging agent, in patients with colorectal cancer and head and neck cancer.

scientific article published on 03 June 2013

Portable PET probes are a novel tool for intraoperative localization of tumor deposits

scientific article published on 21 February 2009

Positron Emission Tomography/Computed Tomography-Based Assessments of Androgen Receptor Expression and Glycolytic Activity as a Prognostic Biomarker for Metastatic Castration-Resistant Prostate Cancer

scientific article published on 9 November 2017

Practical approach for comparative analysis of multilesion molecular imaging using a semiautomated program for PET/CT

scientific article

Predicting gemcitabine delivery by 18F-FAC PET in murine models of pancreatic cancer

scientific article published on 09 July 2020

Predicting hypoxia status using a combination of contrast-enhanced computed tomography and [18F]-Fluorodeoxyglucose positron emission tomography radiomics features.

scientific article published on 19 December 2017

Prediction of absorbed dose to normal organs in thyroid cancer patients treated with 131I by use of 124I PET and 3-dimensional internal dosimetry software.

scientific article published in January 2007

Preoperative characterisation of clear-cell renal carcinoma using iodine-124-labelled antibody chimeric G250 (124I-cG250) and PET in patients with renal masses: a phase I trial.

scientific article

Prognostic value of baseline [18F] fluorodeoxyglucose positron emission tomography and 99mTc-MDP bone scan in progressing metastatic prostate cancer

scientific article

Prognostic value of baseline metabolic tumor volume measured on 18F-fluorodeoxyglucose positron emission tomography/computed tomography in melanoma patients treated with ipilimumab therapy

scientific article published on 28 November 2018

Prospective trial incorporating pre-/mid-treatment [18F]-misonidazole positron emission tomography for head-and-neck cancer patients undergoing concurrent chemoradiotherapy

scientific article published on 7 February 2009

Quantification of bone flare on F-NaF PET/CT in metastatic castration-resistant prostate cancer

scientific article published on 09 November 2018

Quantitative Assessment of Early [18F]Sodium Fluoride Positron Emission Tomography/Computed Tomography Response to Treatment in Men With Metastatic Prostate Cancer to Bone.

scientific article published on 27 June 2017

Quantitative modeling of Cerenkov light production efficiency from medical radionuclides

scientific article

Radiation Dose Assessment for I-131 Therapy of Thyroid Cancer Using I-124 PET Imaging ⬇️

scientific article published on 01 January 1999

Radiation safety considerations for the use of ²²³RaCl₂ DE in men with castration-resistant prostate cancer

scientific article published on April 2014

Radioimmunotargeting of human rhabdomyosarcoma using monoclonal antibody 8H9.

scientific article published on October 2005

Radiosynthesis of [(131)I]IAZGP via nucleophilic substitution and its biological evaluation as a hypoxia marker - is specific activity a factor influencing hypoxia-mapping ability of a hypoxia marker?

scientific article

Radiosynthesis of the tumor hypoxia marker [18F]TFMISO via O-[18F]trifluoroethylation reveals a striking difference between trifluoroethyl tosylate and iodide in regiochemical reactivity toward oxygen nucleophiles

scientific article

Radiotherapy treatment planning for patients with non-small cell lung cancer using positron emission tomography (PET).

scientific article published in January 2002

Rationales, evidence, and design considerations for fractionated radioimmunotherapy

scientific article published in February 2002

Reduction of respiratory motion artifacts in PET imaging of lung cancer by respiratory correlated dynamic PET: methodology and comparison with respiratory gated PET.

scientific article published in October 2003

Relaxed ordered subset preconditioned alternating projection algorithm for PET reconstruction with automated penalty weight selection.

scientific article published on 24 April 2017

Reproducibility and repeatability of semi-quantitative 18F-fluorodihydrotestosterone (FDHT) uptake metrics in castration-resistant prostate cancer metastases: a prospective multi-center study.

scientific article published on 6 April 2018

Reproducibility of (18)F-fluoromisonidazole intratumour distribution in non-small cell lung cancer

scientific article (publication date: December 2016)

Reproducibility of intratumor distribution of (18)F-fluoromisonidazole in head and neck cancer.

scientific article published on January 2008

Reverse-Contrast Imaging and Targeted Radiation Therapy of Advanced Pancreatic Cancer Models.

scientific article

SCDT-38. SAFETY AND EFFICACY OF INTRAVENTRICULAR I-LABELED MONOCLONAL ANTIBODY 8H9 TARGETING THE SURFACE GLYCOPROTEIN B7-H3 IN PATIENTS WITH CNS/LM DISEASE

scientific article published on 06 November 2017

Strategy of Using Intratreatment Hypoxia Imaging to Selectively and Safely Guide Radiation Dose De-escalation Concurrent With Chemotherapy for Locoregionally Advanced Human Papillomavirus-Related Oropharyngeal Carcinoma

scientific article

Study of radiolabeled indium-111 and yttrium-90 ibritumomab tiuxetan in primary central nervous system lymphoma

scientific article published on 01 December 2007

THER-24. TARGETED RADIOIMMUNOTHERAPY FOR EMBRYONAL TUMOR WITH MULTILAYERED ROSETTES

scientific article published on 23 April 2019

TMSOTf assisted synthesis of 2'-deoxy-2'-[18F]fluoro-β-D-arabinofuranosylcytosine ([18F]FAC).

scientific article

Targeted alpha particle immunotherapy for myeloid leukemia

scientific article published on 01 August 2002

Targeted brain tumor radiotherapy using an Auger emitter

scientific article published on 17 February 2020

Targeted radioimmunotherapy for embryonal tumor with multilayered rosettes

scientific article published on 16 March 2019

Technical Note: Scintillation well counters and particle counting digital autoradiography devices can be used to detect activities associated with genomic profiling adequacy of biopsy specimens obtained after a low activity 18 F-FDG injection.

scientific article published on 26 February 2018

The CT motion quantitation of lung lesions and its impact on PET-measured SUVs.

scientific article published in August 2004

The potential of theragnostic ¹²⁴I-8H9 convection-enhanced delivery in diffuse intrinsic pontine glioma

scientific article published on 12 February 2014

The value of gamma camera and computed tomography data set coregistration to assess Lewis Y antigen targeting in small cell lung cancer by (111)Indium-labeled humanized monoclonal antibody 3S193.

scientific article

Tumor Treatment Response Based on Visual and Quantitative Changes in Global Tumor Glycolysis Using PET-FDG Imaging. The Visual Response Score and the Change in Total Lesion Glycolysis.

scientific article published on May 1999

Tumor hypoxia imaging

scientific article published on September 2006

Tumor hypoxia imaging in orthotopic liver tumors and peritoneal metastasis: a comparative study featuring dynamic 18F-MISO and 124I-IAZG PET in the same study cohort

scientific article published on 05 September 2007

Tumor localization of 16beta-18F-fluoro-5alpha-dihydrotestosterone versus 18F-FDG in patients with progressive, metastatic prostate cancer

scientific article published in March 2004

Tumour-specific PI3K inhibition via nanoparticle-targeted delivery in head and neck squamous cell carcinoma

scientific article published on 13 February 2017

Two-compartment model of radioimmunotherapy delivered through cerebrospinal fluid ⬇️

scientific article published on October 9, 2010

Validation of GATE Monte Carlo simulations of the GE Advance/Discovery LS PET scanners.

scientific article published in January 2006

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