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List of works by Harvey A. Risch

A Transcriptome-Wide Association Study Among 97,898 Women to Identify Candidate Susceptibility Genes for Epithelial Ovarian Cancer Risk

article

A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2.

scientific article

A genome-wide association study identifies new susceptibility loci for esophageal adenocarcinoma and Barrett's esophagus

scientific journal article

A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33

scientific article

A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.

scientific article published on 19 September 2010

A multilayered post-GWAS assessment on genetic susceptibility to pancreatic cancer

scientific article published on 01 February 2021

A pooled analysis of dietary sugar/carbohydrate intake and esophageal and gastric cardia adenocarcinoma incidence and survival in the USA.

scientific article

A pooled genome-wide association study identifies pancreatic cancer susceptibility loci on chromosome 19p12 and 19p13.3 in the full-Jewish population

scientific article published on 15 July 2020

A resequence analysis of genomic loci on chromosomes 1q32.1, 5p15.33, and 13q22.1 associated with pancreatic cancer risk

scientific article published on March 2013

Abstract 2167: Infertility and risk of incident endometrial carcinoma: a pooled analysis from the Epidemiology of Endometrial Cancer Consortium

article

Adult body mass index and risk of ovarian cancer by subtype: a Mendelian randomization study

scientific article published on 10 July 2016

Adult height is associated with increased risk of ovarian cancer: a Mendelian randomisation study

scientific article published on 20 March 2018

Agnostic Pathway/Gene Set Analysis of Genome-Wide Association Data Identifies Associations for Pancreatic Cancer.

scientific article published on 12 December 2018

Alcohol dehydrogenase 3 and risk of esophageal and gastric adenocarcinomas

scientific article published on 31 July 2007

An absolute risk model to identify individuals at elevated risk for pancreatic cancer in the general population

scientific article published on 13 September 2013

Analysis of heritability and shared heritability based on genome-wide association studies for thirteen cancer types

journal article published in 2015

Aspirin, nonaspirin nonsteroidal anti-inflammatory drug, and acetaminophen use and risk of invasive epithelial ovarian cancer: a pooled analysis in the Ovarian Cancer Association Consortium

scientific article published on February 2014

Assessing the genetic architecture of epithelial ovarian cancer histological subtypes

scientific article

Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers

scientific article published on 03 July 2020

Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with risk of clear cell ovarian cancer

scientific article published on 21 June 2016

Association Between Breastfeeding and Ovarian Cancer Risk

scientific article published on 02 April 2020

Association Between Menopausal Estrogen-Only Therapy and Ovarian Carcinoma Risk

scientific article

Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study ⬇️

scientific article published on 23 February 2017

Association between endometriosis and risk of histological subtypes of ovarian cancer: a pooled analysis of case-control studies

scientific article published in April 2012

Association of vitamin D levels and risk of ovarian cancer: a Mendelian randomization study

scientific article published on 4 September 2016

BRCA2 Polymorphic Stop Codon K3326X and the Risk of Breast, Prostate, and Ovarian Cancers

scientific article

Biological and Clinical Significance of MAD2L1 and BUB1, Genes Frequently Appearing in Expression Signatures for Breast Cancer Prognosis

scientific article published on 19 August 2015

Carbonated soft drink consumption and risk of esophageal adenocarcinoma

scientific article published in January 2006

Characterization of large structural genetic mosaicism in human autosome

journal article published in 2015

Chronic Recreational Physical Inactivity and Epithelial Ovarian Cancer Risk

article

Chronic Recreational Physical Inactivity and Epithelial Ovarian Cancer Risk: Evidence from the Ovarian Cancer Association Consortium

scientific article

Cigarette smoking and risk of ovarian cancer: a pooled analysis of 21 case-control studies

scientific article published on 02 March 2013

Cigarette smoking is associated with adverse survival among women with ovarian cancer: Results from a pooled analysis of 19 studies

scientific article

Cigarette smoking, body mass index, gastro-esophageal reflux disease, and non-steroidal anti-inflammatory drug use and risk of subtypes of esophageal and gastric cancers by P53 overexpression

scientific article

Cis-eQTL analysis and functional validation of candidate susceptibility genes for high-grade serous ovarian cancer

scientific article published on 22 September 2015

Combined and interactive effects of environmental and GWAS-identified risk factors in ovarian cancer

scientific article published on 05 March 2013

Common Genetic Variation In Cellular Transport Genes and Epithelial Ovarian Cancer (EOC) Risk

scientific article published on 19 June 2015

Common Genetic Variation in Circadian Rhythm Genes and Risk of Epithelial Ovarian Cancer (EOC).

scientific article

Common variants at the CHEK2 gene locus and risk of epithelial ovarian cancer

scientific article

Common variation at 2p13.3, 3q29, 7p13 and 17q25.1 associated with susceptibility to pancreatic cancer

scientific article published on 22 June 2015

Consortium analysis of gene and gene-folate interactions in purine and pyrimidine metabolism pathways with ovarian carcinoma risk

scientific article

Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations

scientific article

Cross-cancer genome-wide association study of endometrial cancer and epithelial ovarian cancer identifies genetic risk regions associated with risk of both cancers

scientific article published on 03 November 2020

Demographic and lifestyle predictors of survival in patients with esophageal or gastric cancers

scientific article

Detectable clonal mosaicism and its relationship to aging and cancer

journal article published in 2012

Diet and lifestyle factors and risk of subtypes of esophageal and gastric cancers: classification tree analysis

scientific article

Dietary flavonoid intake and Barrett's esophagus in western Washington State

scientific article

Early Outpatient Treatment of Symptomatic, High-Risk Covid-19 Patients that Should be Ramped-Up Immediately as Key to the Pandemic Crisis

scientific article published on 27 May 2020

Enrichment of putative PAX8 target genes at serous epithelial ovarian cancer susceptibility loci

scientific article published on 19 January 2017

Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer

scientific article published in 2013

Epithelial-Mesenchymal Transition (EMT) Gene Variants and Epithelial Ovarian Cancer (EOC) Risk

scientific article

European American stratification in ovarian cancer case control data: the utility of genome-wide data for inferring ancestry

scientific article

Evaluating the ovarian cancer gonadotropin hypothesis: a candidate gene study

scientific article published on 17 December 2014

Female chromosome X mosaicism is age-related and preferentially affects the inactivated X chromosome

journal article published in 2016

Fine-mapping of 150 breast cancer risk regions identifies 178 high confidence target genes

article

Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes

scientific article published on 07 January 2020

Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus

scientific article published on 7 September 2016

GST, NAT1, CYP1A1 polymorphisms and risk of esophageal and gastric adenocarcinomas.

scientific article

GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer

scientific article published on April 2013

Genetic analyses of gynecological disease identify genetic relationships between uterine fibroids and endometrial cancer, and a novel endometrial cancer genetic risk region at the WNT4 1p36.12 locus

scientific article published on 15 July 2021

Genital powder use and risk of ovarian cancer: a pooled analysis of 8,525 cases and 9,859 controls

scientific article published on 12 June 2013

Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types

scientific article published in September 2016

Genome-wide Analysis of Common Copy Number Variation and Epithelial Ovarian Cancer Risk

scientific article published on 04 April 2019

Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer

article

Genome-wide association meta-analysis identifies GP2 gene risk variants for pancreatic cancer

scientific article published on 24 June 2020

Genome-wide association study data reveal genetic susceptibility to chronic inflammatory intestinal diseases and pancreatic ductal adenocarcinoma risk

scientific article published on 08 July 2020

Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses

scientific article published on 18 May 2020

Genome-wide association study identifies a possible susceptibility locus for endometrial cancer

scientific article

Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer

scientific article

Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer

scientific article

Genome-wide association study of endometrial cancer in E2C2

scientific article (publication date: February 2014)

Genome-wide association study of subtype-specific epithelial ovarian cancer risk alleles using pooled DNA.

scientific article published on 5 November 2013

Genome-wide gene-diabetes and gene-obesity interaction scan in 8,255 cases and 11,900 controls from the PanScan and PanC4 Consortia

scientific article published on 16 June 2020

Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer

scientific article published on 8 February 2018

Germline copy number variation and ovarian cancer survival

scientific article

History of Comorbidities and Survival of Ovarian Cancer Patients, Results from the Ovarian Cancer Association Consortium

scientific article published on September 2017

Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31.

scientific article published on January 2013

Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

scientific article

Identification of nine new susceptibility loci for endometrial cancer

scientific article published in Nature Communications

Identification of six new susceptibility loci for invasive epithelial ovarian cancer

scientific article published on 12 January 2015

Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33

journal article published in 2014

Increased risk of noncardia gastric cancer associated with proinflammatory cytokine gene polymorphisms

scientific article published on 01 May 2003

Inherited variants affecting RNA editing may contribute to ovarian cancer susceptibility: results from a large-scale collaboration

scientific article published on July 2016

Inherited variants in mitochondrial biogenesis genes may influence epithelial ovarian cancer risk

scientific article

Intrauterine devices and endometrial cancer risk: a pooled analysis of the Epidemiology of Endometrial Cancer Consortium

scientific article published on 30 September 2014

LIN28B polymorphisms influence susceptibility to epithelial ovarian cancer

scientific article published on 11 April 2011

Mendelian randomization analyses suggest a role for cholesterol in the development of endometrial cancer

scientific article published on 13 July 2020

Mendelian randomization analysis of n-6 polyunsaturated fatty acid levels and pancreatic cancer risk

scientific article published on 23 September 2020

MicroRNA processing and binding site polymorphisms are not replicated in the Ovarian Cancer Association Consortium

scientific article published on 2 June 2011

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

scientific article published on April 2013

Network-Based Integration of GWAS and Gene Expression Identifies a HOX-Centric Network Associated with Serous Ovarian Cancer Risk

scientific article

No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer.

scientific article published in May 2015

Nonsteroidal anti-inflammatory drug use associated with reduced incidence of adenocarcinomas of the esophagus and gastric cardia that overexpress cyclin D1: a population-based study

scientific article (publication date: 2004)

Obesity and risk of ovarian cancer subtypes: evidence from the Ovarian Cancer Association Consortium

scientific article published on 22 March 2013

Occupation and risk of esophageal and gastric cardia adenocarcinoma

scientific article published on 01 July 2002

Offspring sex and risk of epithelial ovarian cancer: a multinational pooled analysis of 12 case-control studies

scientific article published on 21 September 2020

Pancreatic Cancer Risk is Modulated by Inflammatory Potential of Diet and ABO Genotype: A Consortia-based Evaluation and Replication Study

Pathophysiological Basis and Rationale for Early Outpatient Treatment of SARS-CoV-2 (COVID-19) Infection

scientific article published on 06 August 2020

Pathway analysis of genome-wide association study data highlights pancreatic development genes as susceptibility factors for pancreatic cancer

scientific article

Physical activity and breast cancer survival: an epigenetic link through reduced methylation of a tumor suppressor gene L3MBTL1 ⬇️

scientific article published on August 12, 2011

Polymorphisms in Genes of Relevance for Oestrogen and Oxytocin Pathways and Risk of Barrett's Oesophagus and Oesophageal Adenocarcinoma: A Pooled Analysis from the BEACON Consortium ⬇️

scientific article

Polymorphisms in inflammation pathway genes and endometrial cancer risk

scientific article published on 5 December 2012

Population attributable risks of esophageal and gastric cancers

scientific article published in September 2003

Pregnancy Outcomes and Risk of Endometrial Cancer: A Pooled Analysis of Individual Participant Data in the Epidemiology of Endometrial Cancer Consortium

scientific article published on 26 October 2020

Principal Component Analysis of Dietary and Lifestyle Patterns in Relation to Risk of Subtypes of Esophageal and Gastric Cancer ⬇️

scientific article published on March 23, 2011

Prognostic and predictive values of long non-coding RNA LINC00472 in breast cancer

scientific article published in April 2015

Publisher Correction: Shared heritability and functional enrichment across six solid cancers

scientific article published on 23 September 2019

Recreational physical inactivity and mortality in women with invasive epithelial ovarian cancer: evidence from the Ovarian Cancer Association Consortium

scientific article

Risk Factors for Early-Onset and Very-Early-Onset Pancreatic Adenocarcinoma: A Pancreatic Cancer Case-Control Consortium (PanC4) Analysis

scientific article

Risk Prediction for Epithelial Ovarian Cancer in 11 United States-Based Case-Control Studies: Incorporation of Epidemiologic Risk Factors and 17 Confirmed Genetic Loci

scientific article

Risk of breast cancer after a diagnosis of ovarian cancer in BRCA mutation carriers: Is preventive mastectomy warranted?

scientific article published on 14 March 2017

Risk of ovarian cancer and the NF-κB pathway: genetic association with IL1A and TNFSF10

scientific article published on 22 November 2013

Robust Tests for Additive Gene-Environment Interaction in Case-Control Studies Using Gene-Environment Independence

scientific article published on 14 June 2017

Shared genetics underlying epidemiological association between endometriosis and ovarian cancer

scientific article published on 30 July 2015

Shared heritability and functional enrichment across six solid cancers

scientific article published in Nature Communications

Shared heritability and functional enrichment across six solid cancers

Telomerase expression and telomere length in breast cancer and their associations with adjuvant treatment and disease outcome

scientific article published on 6 June 2011

Telomere structure and maintenance gene variants and risk of five cancer types

scientific article published on 15 December 2016

The association between socioeconomic status and tumour stage at diagnosis of ovarian cancer: A pooled analysis of 18 case-control studies

scientific article published on 3 February 2016

The role of KRAS rs61764370 in invasive epithelial ovarian cancer: implications for clinical testing

scientific article published on 8 March 2011

Transcriptome-wide association study of breast cancer risk by estrogen-receptor status

scientific article published on 01 March 2020

Tubal ligation and risk of ovarian cancer subtypes: a pooled analysis of case-control studies

scientific article

Variants in genes encoding small GTPases and association with epithelial ovarian cancer susceptibility

scientific article published in PLoS ONE

Winner's Curse Correction and Variable Thresholding Improve Performance of Polygenic Risk Modeling Based on Genome-Wide Association Study Summary-Level Data

scientific article (publication date: December 2016)

Winners curse correction and variable thresholding improve performance of polygenic risk modeling based on summary-level data from genome-wide association studies

scientific article published on 10 January 2016

rs495139 in the TYMS-ENOSF1 Region and Risk of Ovarian Carcinoma of Mucinous Histology

scientific article published on 21 August 2018

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