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List of works by Agnes Görlach

Accounting for biological variation in differential display two-dimensional electrophoresis experiments ⬇️

scientific article published on April 11, 2012

Atrial natriuretic peptide induces mitogen-activated protein kinase phosphatase-1 in human endothelial cells via Rac1 and NAD(P)H oxidase/Nox2-activation

scientific article published on 29 November 2004

Calcium and ROS: A mutual interplay

scientific article

Circular RNA maps paving the road to biomarker development?

scientific article published on 24 October 2017

Comparative characterization of cellular and molecular anti-restenotic profiles of paclitaxel and sirolimus. Implications for local drug delivery.

scientific article published in June 2007

Control of adenosine transport by hypoxia

scientific article published in July 2005

Cross Talk Between p22phox and ATF4 in the Endothelial Unfolded Protein Response

scientific article published on 05 September 2018

Deficiency of HIF1α in Antigen-Presenting Cells Aggravates Atherosclerosis and Type 1 T-Helper Cell Responses in Mice.

scientific article

Deficiency of manganese superoxide dismutase in hepatocytes disrupts zonated gene expression in mouse liver

scientific journal article

Delineating the angiogenic gene expression profile before pulmonary vascular remodeling in a lamb model of congenital heart disease ⬇️

scientific article published on October 26, 2010

Differential transcriptional regulation of hypoxia-inducible factor-1α by arsenite under normoxia and hypoxia: involvement of Nrf2

scientific article

Early determinants of pulmonary vascular remodeling in animal models of complex congenital heart disease

scientific article published on March 2011

European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS).

scientific article published on 18 May 2017

Folic Acid Promotes Recycling of Tetrahydrobiopterin and Protects Against Hypoxia-Induced Pulmonary Hypertension by Recoupling Endothelial Nitric Oxide Synthase

scientific article published on 28 September 2015

Functional analyses reveal the greater potency of preadipocytes compared with adipocytes as endothelial cell activator under normoxia, hypoxia, and TNFalpha exposure

scientific article published on 23 June 2009

GSK-3β regulates cell growth, migration, and angiogenesis via Fbw7 and USP28-dependent degradation of HIF-1α ⬇️

scientific article published on December 5, 2011

Glycogen synthase kinase 3 phosphorylates hypoxia-inducible factor 1alpha and mediates its destabilization in a VHL-independent manner

scientific article published on 26 February 2007

HIF-1α is required for development of the sympathetic nervous system

scientific article published on 13 June 2019

Heterocyclic indazole derivatives as SGK1 inhibitors, WO2008138448.

scientific article published on January 2010

Human urotensin II is a novel activator of NADPH oxidase in human pulmonary artery smooth muscle cells

scientific article

Hypoxia up-regulates hypoxia-inducible factor-1alpha transcription by involving phosphatidylinositol 3-kinase and nuclear factor kappaB in pulmonary artery smooth muscle cells

scientific article

Identification of a survival-independent metastasis-enhancing role of hypoxia-inducible factor-1alpha with a hypoxia-tolerant tumor cell line

scientific article

Immunoproteasome subunit ß5i/LMP7-deficiency in atherosclerosis

scientific article published on 17 October 2017

Inhibition of endothelial nitric oxyde synthase increases capillary formation via Rac1-dependent induction of hypoxia-inducible factor-1α and plasminogen activator inhibitor-1 ⬇️

scientific article published on September 26, 2012

Insights into the redox control of blood coagulation: role of vascular NADPH oxidase-derived reactive oxygen species in the thrombogenic cycle

scientific article published in August 2004

Mitochondrial Dysfunction Due to Lack of Manganese Superoxide Dismutase Promotes Hepatocarcinogenesis

scientific article

NADPH oxidase is internalized by clathrin-coated pits and localizes to a Rab27A/B GTPase-regulated secretory compartment in activated macrophages

scientific article

NADPH oxidase mediates tissue factor-dependent surface procoagulant activity by thrombin in human vascular smooth muscle cells

scientific article

NADPH oxidases and HIF1 promote cardiac dysfunction and pulmonary hypertension in response to glucocorticoid excess

scientific article published on 11 April 2020

NOX1 supports the metabolic remodeling of HepG2 cells

scientific article

NOX2 and NOX4 mediate proliferative response in endothelial cells.

scientific article published on September 2006

NOX4 mediates activation of FoxO3a and matrix metalloproteinase-2 expression by urotensin-II

scientific article published on 30 September 2011

NOX5 variants are functionally active in endothelial cells

scientific article

Phosphodiesterase 2 mediates redox-sensitive endothelial cell proliferation and angiogenesis by thrombin via Rac1 and NADPH oxidase 2.

scientific article published on 23 April 2009

Prolyl-hydroxylase inhibition induces SDF-1 associated with increased CXCR4+/CD11b+ subpopulations and cardiac repair

scientific article published on 26 May 2017

Rac regulates thrombin-induced tissue factor expression in pulmonary artery smooth muscle cells involving the nuclear factor-kappaB pathway

scientific article

Rac-1 promotes pulmonary artery smooth muscle cell proliferation by upregulation of plasminogen activator inhibitor-1: role of NFkappaB-dependent hypoxia-inducible factor-1alpha transcription

scientific article published on 01 December 2008

Reactive oxygen species activate the HIF-1alpha promoter via a functional NFkappaB site

scientific article

Reactive oxygen species in the control of hypoxia-inducible factor-mediated gene expression.

scientific article

Reactive oxygen species modulate HIF-1 mediated PAI-1 expression: involvement of the GTPase Rac1

scientific journal article

Reactive oxygen species, nutrition, hypoxia and diseases: Problems solved?

scientific article

Receptor activation of NADPH oxidases

scientific article published on August 2010

Reciprocal regulation of Rac1 and PAK-1 by HIF-1alpha: a positive-feedback loop promoting pulmonary vascular remodeling

scientific article

Redox control of blood coagulation

scientific article published on 01 August 2004

Redox control of tissue factor expression in smooth muscle cells and other vascular cells

scientific article

Redox regulation of genome stability by effects on gene expression, epigenetic pathways and DNA damage/repair.

scientific article published on 3 June 2015

Redox regulation of the coagulation cascade

scientific article

Redox signaling through NADPH oxidases: involvement in vascular proliferation and coagulation

scientific article published on November 2002

Redox-sensitive regulation of the HIF pathway under non-hypoxic conditions in pulmonary artery smooth muscle cells

scientific article published on March 2004

Regulation of HIF-1alpha at the transcriptional level

scientific article published on January 2009

Regulation of NADPH Oxidases by G Protein-Coupled Receptors

scientific article published on 25 April 2018

Regulation of proliferation of skeletal muscle precursor cells by NADPH oxidase

scientific article

Regulation of the hypoxia-dependent plasminogen activator inhibitor 1 expression by MAP kinases

scientific article published on 01 April 2003

Regulation of the hypoxia-inducible transcription factor HIF-1 by reactive oxygen species in smooth muscle cells.

scientific article published on January 2003

SGK1-dependent cardiac CTGF formation and fibrosis following DOCA treatment.

scientific article

STEAP1 is associated with the invasive and oxidative stress phenotype of Ewing tumors

scientific article

Stabilization of p22phox by Hypoxia Promotes Pulmonary Hypertension

scientific article published on 18 October 2018

Superoxide and derived reactive oxygen species in the regulation of hypoxia-inducible factors.

scientific article published on January 2007

Superoxide-Generating Nox5α Is Functionally Required for the Human T-Cell Leukemia Virus Type 1-Induced Cell Transformation Phenotype

scientific article

Taking advantage of tumor cell adaptations to hypoxia for developing new tumor markers and treatment strategies

scientific article published on April 2009

Targeting SGK1 in diabetes

scientific article

Targeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: the METOXIA consortium

scientific article

The 'PAI-1 paradox' in vascular remodeling

scientific article published in December 2008

The HIF1 target geneNOX2promotes angiogenesis through urotensin-II ⬇️

scientific article published on February 15, 2012

The NADPH oxidase subunit NOX4 is a new target gene of the hypoxia-inducible factor-1.

scientific article

The cross-talk between NF-kappaB and HIF-1: further evidence for a significant liaison

scientific article published on 01 June 2008

The endoplasmic reticulum: folding, calcium homeostasis, signaling, and redox control

scientific article published on September 2006

The epigenetic landscape related to reactive oxygen species formation in the cardiovascular system

scientific article published on 23 March 2017

The expression of the NADPH oxidase subunit p22phox is regulated by a redox-sensitive pathway in endothelial cells

scientific article

The hypoxia-inducible factor HIF-1 promotes intramyocardial expression of VEGF in infants with congenital cardiac defects

scientific article published on 02 February 2007

The hypoxia-inducible factor-2alpha is stabilized by oxidative stress involving NOX4.

scientific article

The role of hypoxia inducible factor-1 in cell metabolism--a possible target in cancer therapy

scientific article published on August 2006

The role of nitric oxide radicals in removal of hyper-radiosensitivity by priming irradiation.

scientific article published on 17 May 2013

The serum- and glucocorticoid-inducible kinase Sgk-1 is involved in pulmonary vascular remodeling: role in redox-sensitive regulation of tissue factor by thrombin

scientific article published on 16 February 2006

The vascular NADPH oxidase subunit p47phox is involved in redox-mediated gene expression.

scientific article

The β3-integrin binding protein β3-endonexin is a novel negative regulator of hypoxia-inducible factor-1.

scientific article published on 13 March 2014

Thrombin activates the p21-activated kinase in pulmonary artery smooth muscle cells. Role in tissue factor expression

scientific article published on 01 June 2005

Tissue inhibitor of metalloproteinases-1-induced scattered liver metastasis is mediated by hypoxia-inducible factor-1α ⬇️

scientific article published on October 30, 2010

Toll-like receptor 3 regulates angiogenesis and apoptosis in prostate cancer cell lines through hypoxia-inducible factor 1 alpha

scientific article

Transit of H2O2 across the endoplasmic reticulum membrane is not sluggish

scientific article

Urotensin-II in the lung: a matter for vascular remodelling and pulmonary hypertension?

scientific article published on 01 November 2007

Vascular remodelling processes: cells, signals and their integration

scientific article published on 01 November 2007

Volumetric optoacoustic tomography enables non-invasive in vivo characterization of impaired heart function in hypoxic conditions

scientific article published on 10 June 2019

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