List of works - Marianna Gaça

A comparative assessment of e-cigarette aerosols and cigarette smoke on in vitro endothelial cell migration

scientific article

A novel hybrid tobacco product that delivers a tobacco flavour note with vapour aerosol (Part 2): In vitro biological assessment and comparison with different tobacco-heating products

scientific article published on 30 May 2017

Alternative approaches for acute inhalation toxicity testing to address global regulatory and non-regulatory data requirements: An international workshop report.

scientific article

An inter-laboratory in vitro assessment of cigarettes and next generation nicotine delivery products

scientific article published on 07 August 2019

Application of dosimetry tools for the assessment of e-cigarette aerosol and cigarette smoke generated on two different in vitro exposure systems.

scientific article

Assessing modified risk tobacco and nicotine products: Description of the scientific framework and assessment of a closed modular electronic cigarette

scientific article published on 22 September 2017

Assessment of in vitro COPD models for tobacco regulatory science: Workshop proceedings, conclusions and paths forward for in vitro model use.

scientific article published in May 2016

Assessment of novel tobacco heating product THP1.0. Part 6: A comparative in vitro study using contemporary screening approaches

scientific article published on 4 September 2017

Assessment of novel tobacco heating product THP1.0. Part 7: Comparative in vitro toxicological evaluation

scientific article published on 5 September 2017

Assessment of tobacco heating product THP1.0. Part 5: In vitro dosimetric and cytotoxic assessment

scientific article

Assessment of tobacco heating product THP1.0. Part 9: The placement of a range of next-generation products on an emissions continuum relative to cigarettes via pre-clinical assessment studies

scientific article published on 5 October 2017

Comparative tumor promotion assessment of e-cigarette and cigarettes using the in vitro Bhas 42 cell transformation assay

scientific article

E-cigarette aerosols induce lower oxidative stress in vitro when compared to tobacco smoke

scientific article published on July 2016

Electronic cigarette aerosol induces significantly less cytotoxicity than tobacco smoke

scientific article published on July 2016

Evaluation of precision and accuracy of the Borgwaldt RM20S(®) smoking machine designed for in vitro exposure

scientific article published on December 2010

Genotoxicity evaluation of tobacco and nicotine delivery products: Part One. Mouse lymphoma assay

scientific article published on 20 June 2019

Genotoxicity evaluation of tobacco and nicotine delivery products: Part Two. In vitro micronucleus assay

scientific article published on 01 June 2019

Implementation challenges for designing Integrated In Vitro Testing Strategies (ITS) aiming at reducing and replacing animal experimentation ⬇️

scientific article published on January 17, 2012

In vitro RNA-seq-based toxicogenomics assessment shows reduced biological effect of tobacco heating products when compared to cigarette smoke

scientific article published on 5 February 2018

In vitro models of inhalation toxicity and disease. The report of a FRAME workshop

scientific article published on 01 February 2009

Pathway-based predictive approaches for non-animal assessment of acute inhalation toxicity

scientific article published on 20 June 2018

Reduced biological effect of e-cigarette aerosol compared to cigarette smoke evaluated in vitro using normalized nicotine dose and RNA-seq-based toxicogenomics

scientific article

State of the art on alternative methods to animal testing from an industrial point of view: ready for regulation?

scientific article published on 4 May 2014

The role of oxidative stress in the biological responses of lung epithelial cells to cigarette smoke

scientific article

Toxicology in the 21st century – Working our way towards a visionary reality ⬇️

scientific article published on February 19, 2011

List of works by Marianna Gaça

A comparative assessment of e-cigarette aerosols and cigarette smoke on in vitro endothelial cell migration

A novel hybrid tobacco product that delivers a tobacco flavour note with vapour aerosol (Part 2): In vitro biological assessment and comparison with different tobacco-heating products

Alternative approaches for acute inhalation toxicity testing to address global regulatory and non-regulatory data requirements: An international workshop report.

An inter-laboratory in vitro assessment of cigarettes and next generation nicotine delivery products

Application of dosimetry tools for the assessment of e-cigarette aerosol and cigarette smoke generated on two different in vitro exposure systems.

Assessing modified risk tobacco and nicotine products: Description of the scientific framework and assessment of a closed modular electronic cigarette

Assessment of in vitro COPD models for tobacco regulatory science: Workshop proceedings, conclusions and paths forward for in vitro model use.

Assessment of novel tobacco heating product THP1.0. Part 6: A comparative in vitro study using contemporary screening approaches

Assessment of novel tobacco heating product THP1.0. Part 7: Comparative in vitro toxicological evaluation

Assessment of tobacco heating product THP1.0. Part 5: In vitro dosimetric and cytotoxic assessment

Assessment of tobacco heating product THP1.0. Part 9: The placement of a range of next-generation products on an emissions continuum relative to cigarettes via pre-clinical assessment studies

Comparative tumor promotion assessment of e-cigarette and cigarettes using the in vitro Bhas 42 cell transformation assay

E-cigarette aerosols induce lower oxidative stress in vitro when compared to tobacco smoke

Electronic cigarette aerosol induces significantly less cytotoxicity than tobacco smoke

Evaluation of precision and accuracy of the Borgwaldt RM20S(®) smoking machine designed for in vitro exposure

Genotoxicity evaluation of tobacco and nicotine delivery products: Part One. Mouse lymphoma assay

Genotoxicity evaluation of tobacco and nicotine delivery products: Part Two. In vitro micronucleus assay

Implementation challenges for designing Integrated In Vitro Testing Strategies (ITS) aiming at reducing and replacing animal experimentation ⬇️

In vitro RNA-seq-based toxicogenomics assessment shows reduced biological effect of tobacco heating products when compared to cigarette smoke

In vitro models of inhalation toxicity and disease. The report of a FRAME workshop

Pathway-based predictive approaches for non-animal assessment of acute inhalation toxicity

Reduced biological effect of e-cigarette aerosol compared to cigarette smoke evaluated in vitro using normalized nicotine dose and RNA-seq-based toxicogenomics

State of the art on alternative methods to animal testing from an industrial point of view: ready for regulation?

The role of oxidative stress in the biological responses of lung epithelial cells to cigarette smoke

Toxicology in the 21st century – Working our way towards a visionary reality ⬇️