Search filters

List of works by Helena Therese Högberg

3D Differentiation of LUHMES Cell Line to Study Recovery and Delayed Neurotoxic Effects

scientific article

A Brainer on Neurotoxicity

scientific article published on 30 June 2020

A human brain microphysiological system derived from induced pluripotent stem cells to study neurological diseases and toxicity

scientific article published on 24 November 2016

A human stem cell-based model for identifying adverse effects of organic and inorganic chemicals on the developing nervous system.

scientific article

Antidepressant Paroxetine Exerts Developmental Neurotoxicity in an iPSC-Derived 3D Human Brain Model

scientific article published on 21 February 2020

Application of micro-electrode arrays (MEAs) as an emerging technology for developmental neurotoxicity: evaluation of domoic acid-induced effects in primary cultures of rat cortical neurons

scientific article published on 5 November 2010

Biological and medical applications of a brain-on-a-chip

scientific article (publication date: September 2014)

Biology-inspired microphysiological systems to advance patient benefit and animal welfare in drug development

scientific article published on 28 February 2020

Brain-on-a-chip model enables analysis of human neuronal differentiation and chemotaxis

scientific article published in October 2016

Characterization of three human cell line models for high-throughput neuronal cytotoxicity screening.

scientific article published on 3 May 2016

Consensus statement on the need for innovation, transition and implementation of developmental neurotoxicity (DNT) testing for regulatory purposes

scientific article published on 12 February 2018

Corrigendum to Recommendation on test readiness criteria for new approach methods in toxicology: exemplified for developmental neurotoxicity

scientific article published on 01 January 2019

Developmental neurotoxicity - challenges in the 21st century and in vitro opportunities

scientific article

Domoic Acid-Induced Neurotoxicity Is Mainly Mediated by the AMPA/KA Receptor: Comparison between Immature and Mature Primary Cultures of Neurons and Glial Cells from Rat Cerebellum

scientific article published on 2 November 2011

Explosive Blast Loading on Human 3D Aggregate Minibrains

scientific article published on 21 January 2017

Gene expression as a sensitive endpoint to evaluate cell differentiation and maturation of the developing central nervous system in primary cultures of rat cerebellar granule cells (CGCs) exposed to pesticides

scientific article published on 25 December 2008

In vitro developmental neurotoxicity (DNT) testing: relevant models and endpoints

scientific article published on 5 December 2009

Infectability of human BrainSphere neurons suggests neurotropism of SARS-CoV-2

scientific article published on 26 June 2020

International STakeholder NETwork (ISTNET): creating a developmental neurotoxicity (DNT) testing road map for regulatory purposes

scientific article

Mapping the human toxome by systems toxicology.

scientific article

Metabolomics in toxicology and preclinical research

scientific article published on January 2013

Metabolomics reveals metabolic alterations by intrauterine growth restriction in the fetal rabbit brain

scientific article

Microglia Increase Inflammatory Responses in iPSC-Derived Human BrainSpheres

article

Nanotoxicology: "the end of the beginning" - signs on the roadmap to a strategy for assuring the safe application and use of nanomaterials

journal article published in 2011

Quality assurance of metabolomics.

scientific article published on January 2015

Recommendation on test readiness criteria for new approach methods in toxicology: Exemplified for developmental neurotoxicity

scientific article published on 23 February 2018

Reference compounds for alternative test methods to indicate developmental neurotoxicity (DNT) potential of chemicals: example lists and criteria for their selection and use.

scientific article

Relevance of in vitro neurotoxicity testing for regulatory requirements: challenges to be considered

scientific article published on 24 December 2008

Review: toxicometabolomics

scientific article

Rotenone exerts developmental neurotoxicity in a human brain spheroid model.

scientific article published on 8 February 2018

State-of-the-art of 3D cultures (organs-on-a-chip) in safety testing and pathophysiology

scientific article

Suitability of 3D human brain spheroid models to distinguish toxic effects of gold and poly-lactic acid nanoparticles to assess biocompatibility for brain drug delivery.

scientific article published on 3 June 2019

Toward Good In Vitro Reporting Standards

scientific article published on 01 January 2019

Toward a 3D model of human brain development for studying gene/environment interactions

scientific article

Toxicity, recovery, and resilience in a 3D dopaminergic neuronal in vitro model exposed to rotenone

scientific article published on 28 June 2018

mRNA expression is a relevant tool to identify developmental neurotoxicants using an in vitro approach

scientific article published on 3 August 2009

t4 workshop report: Pathways of Toxicity

scientific article (publication date: 2014)

β1-Adrenergic receptors increase UCP1 in human MADS brown adipocytes and rescue cold-acclimated β3-adrenergic receptor-knockout mice via nonshivering thermogenesis

article