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List of works by Hisashi Higuchi

A three-factor model of the MADRS in major depressive disorder

scientific article published in January 2005

Addition of a Dopamine Agonist, Cabergoline, to a Serotonin-Noradrenalin Reuptake Inhibitor, Milnacipran as a Therapeutic Option in the Treatment of Refractory Depression: Two Case Reports ⬇️

scientific article published on September 1, 2003

Association between -1438G/A promoter polymorphism in the 5-HT(2A) receptor gene and fluvoxamine response in Japanese patients with major depressive disorder.

scientific article published in January 2002

Association between serotonin transporter polymorphisms (5-HTTLPR) and the MADRS Dysphoria, Retardation, and Vegetative Subscale scores in the treatment of depression

scientific article

Augmentation with olanzapine in TCA-refractory depression with melancholic features: a consecutive case series

scientific article published on April 2008

Bcl1 polymorphism of the glucocorticoid receptor gene and treatment response to milnacipran and fluvoxamine in Japanese patients with depression

scientific article published on 24 October 2014

Differential clinical effects of fluvoxamine by the effect of age in Japanese female major depressive patients.

scientific article published on 08 April 2009

Effect of quetiapine in the treatment of panic attacks in patients with schizophrenia: 3 case reports

scientific article published in January 2004

Effectiveness of milnacipran for the treatment of chronic pain: a case series

scientific article published in September 2004

Effectiveness of switching to quetiapine for neuroleptic-induced amenorrhea

scientific article published in January 2003

Effects of the CYP 2D6 genotype and cigarette smoking on the steady-state plasma concentrations of fluvoxamine and its major metabolite fluvoxamino acid in Japanese depressed patients

scientific article published in August 2003

Efficacy of milnacipran in the treatment of chronic pain syndromes

scientific article published on 29 December 2009

Ejaculation after defecation without orgasm induced by milnacipran

scientific article published in January 2004

Elevation of blood pressure induced by high-dose milnacipran

scientific article published in December 2002

Favorable effect of milnacipran on depression induced by interferon-alpha

scientific article published in January 2003

Fluvoxamine augmentation in risperidone-resistant schizophrenia: an open trial

scientific article published in March 2002

Gender differences in the clinical effects of fluvoxamine and milnacipran in Japanese major depressive patients

scientific article published in August 2007

Genetic polymorphisms in the serotonergic system and symptom clusters of major depressive disorder

scientific article published on 13 September 2011

Genomewide high-density SNP linkage analysis of 236 Japanese families supports the existence of schizophrenia susceptibility loci on chromosomes 1p, 14q, and 20p.

scientific article

High-performance liquid chromatographic determination of fluvoxamine and fluvoxamino acid in human plasma

scientific article published in June 2003

Influence of serotonergic/noradrenergic gene polymorphisms on nausea and sweating induced by milnacipran in the treatment of depression

scientific article published on January 2009

Influence of the serotonin transporter gene-linked polymorphic region on the antidepressant response to fluvoxamine in Japanese depressed patients.

scientific article published in February 2002

Influence of the tyrosine hydroxylase val81met polymorphism and catechol-O-methyltransferase val158met polymorphism on the antidepressant effect of milnacipran

scientific article published in March 2008

Management of phantom limb pain and sensation with milnacipran

scientific article published in January 2008

Marked effect of milnacipran combined with olanzapine for a delusional depressive patient.

scientific article published on December 2005

Milnacipran for the treatment of chronic pain ⬇️

scientific article published on October 1, 2003

Milnacipran plasma levels and antidepressant response in Japanese major depressive patients

scientific article published in June 2003

Milnacipran treatment of a terminally ill cancer patient with major depressive disorder

scientific article

Monoamine oxidase A gene polymorphism, 5-HT 2A receptor gene polymorphism and incidence of nausea induced by fluvoxamine

scientific article published in January 2003

Monoamine oxidase: A gene polymorphism, tryptophan hydroxylase gene polymorphism and antidepressant response to fluvoxamine in Japanese patients with major depressive disorder

scientific article

No association between the serotonergic polymorphisms and incidence of nausea induced by fluvoxamine treatment

scientific article

No association of the G1287A polymorphism in the norepinephrine transporter gene and susceptibility to major depressive disorder in a Japanese population

scientific article

No predictors of antidepressant patient response to milnacipran were obtained using the three-factor structures of the Montgomery and Asberg Depression Rating Scale in Japanese patients with major depressive disorders

scientific article

Peripheral circulatory disturbance induced by milnacipran

scientific article published in January 2005

Prediction of antidepressant response to milnacipran and fluvoxamine using pharmacogenetical methods

scientific article published in April 2010

Prediction of antidepressant response to milnacipran by norepinephrine transporter gene polymorphisms.

scientific article published in September 2004

Predictors of antidepressant response to fluvoxamine obtained using the three-factor structures of the Montgomery and Asberg Depression Rating Scale for major depressive disorders in Japanese patients

scientific article

Predictors of response to electroconvulsive therapy obtained using the three-factor structure of the Montgomery and Asberg Depression Rating Scale for treatment-resistant depressed patients

scientific article published in June 2010

Probable Aripiprazole-Induced Tardive Writer's Cramp ⬇️

scientific article published on 01 January 2012

Quetiapine treatment of psychotic symptoms and aggressive behavior in patients with dementia with Lewy bodies: A case series ⬇️

scientific article published on May 1, 2003

Rapid worsening of depressive symptoms in a patient with depression after switching from a TCA to an SSRI.

scientific article published in January 2002

Relationship between clinical effects of fluvoxamine and the steady-state plasma concentrations of fluvoxamine and its major metabolite fluvoxamino acid in Japanese depressed patients

scientific article published on 8 April 2003

Remarkable effect of milnacipran in the treatment of Japanese major depressive patients

scientific article published in June 2002

Remarkable effect of milnacipran, a serotonin-noradrenalin reuptake inhibitor (SNRI), on depressive symptoms in patients with Parkinson's disease who have insufficient response to selective serotonin reuptake inhibitors (SSRIs): two case reports

scientific article published on 29 December 2004

Remarkable effect of selegiline (L-deprenyl), a selective monoamine oxidase type-B inhibitor, in a patient with severe refractory depression: a case report

scientific article published in July 2005

Response rate obtained using milnacipran depending on the severity of depression in the treatment of major depressive patients

scientific article published in January 2006

Switching to olanzapine after unsuccessful treatment with risperidone during the first episode of schizophrenia: an open-label trial.

scientific article published on October 2006

Switching to risperidone after unsuccessful treatment of olanzapine in the first-episode schizophrenia: an open trial

scientific article published on 8 June 2006

Symptom predictors of response to electroconvulsive therapy in older patients with treatment-resistant depression

scientific article published on 8 July 2011

Tardive dystonia and genetic polymorphisms of cytochrome P4502D6 and dopamine D2 and D3 receptors: a preliminary finding

scientific article

The G196A polymorphism of the brain-derived neurotrophic factor gene and the antidepressant effect of milnacipran and fluvoxamine

scientific article published on 8 November 2006

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