List of works - Linlin Bao

A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury

scientific article

A single-amino-acid substitution in the HA protein changes the replication and pathogenicity of the 2009 pandemic A (H1N1) influenza viruses in vitro and in vivo ⬇️

scientific article published on November 18, 2010

Adaption of Seasonal H1N1 Influenza Virus in Mice ⬇️

scientific article published on December 16, 2011

An animal model of MERS produced by infection of rhesus macaques with MERS coronavirus

scientific article published on 11 November 2013

Antigenicity and transmissibility of a novel clade 2.3.2.1 avian influenza H5N1 virus

scientific article published on 28 September 2013

Challenge and polymorphism analysis of the novel A (H1N1) influenza virus to normal animals

scientific article

Characterization of Two Human Monoclonal Antibodies Neutralizing Influenza A H7N9 Viruses

scientific article published on 10 June 2015

Characterization of an H9N2 avian influenza virus from a Fringilla montifringilla brambling in northern China

scientific article published on 5 January 2015

Clinical and Biological Character in Mouse Models for Middle East Respiratory Syndrome Generated by Transduction with Different Doses of DPP4 Molecule

scientific article

Combinations of oseltamivir and fibrates prolong the mean survival time of mice infected with the lethal H7N9 influenza virus

scientific article published on October 2014

Comparative pathology of rhesus macaque and common marmoset animal models with Middle East respiratory syndrome coronavirus

scientific article

Correction to: The mouse and ferret models for studying the novel avian-origin human influenza A (H7N9) virus

scientific article published on 24 June 2020

Correction: Genomic Polymorphism of the Pandemic A (H1N1) Influenza Viruses Correlates with Viral Replication, Virulence, and Pathogenicity In Vitro and In Vivo

scientific article published on 06 July 2020

Determination of Influenza Virus H5N1 and H7N9 Using MASA Technology

scientific article published on November 2015

Development of an Inactivated Vaccine Candidate, BBIBP-CorV, with Potent Protection against SARS-CoV-2

scientific article published on 06 June 2020

Distribution of enterovirus 71 RNA in inflammatory cells infiltrating different tissues in fatal cases of hand, foot, and mouth disease

scientific article published on 19 November 2014

Diverse biological characteristics and varied virulence of H7N9 from Wave 5

Enhanced protection in mice induced by immunization with inactivated whole viruses compare to spike protein of middle east respiratory syndrome coronavirus.

scientific article

From SARS to MERS, Thrusting Coronaviruses into the Spotlight

article by Zhiqi Song et al published 14 January 2019 in Viruses

Genomic Polymorphism of the Pandemic A (H1N1) Influenza Viruses Correlates with Viral Replication, Virulence, and Pathogenicity In Vitro and In Vivo ⬇️

scientific article published on June 15, 2011

Hemagglutinin amino acids related to receptor specificity could affect the protection efficacy of H5N1 and H7N9 avian influenza virus vaccines in mice.

scientific article

Higher Immunological Protection of Pandemic 2009 H1N1 Influenza Live Virus Infection than Split Vaccine Against the Homologous Virus for Long Term Immunization in Ferret.

scientific article

Highly pathogenic avian influenza H5N1 virus could partly be evacuated by pregnant BALB/c mouse during abortion or preterm delivery ⬇️

scientific article published on July 8, 2011

Histopathological features and distribution of EV71 antigens and SCARB2 in human fatal cases and a mouse model of enterovirus 71 infection

scientific article published on 16 May 2014

Human Neutralizing Monoclonal Antibody Inhibition of Middle East Respiratory Syndrome Coronavirus Replication in the Common Marmoset.

scientific article published on 2 May 2017

Human monoclonal antibodies targeting the haemagglutinin glycoprotein can neutralize H7N9 influenza virus.

scientific article

Human-Derived A/Guangdong/Th005/2017 (H7N9) Exhibits Extremely High Replication in the Lungs of Ferrets and Is Highly Pathogenic in Chickens

scientific article published on 29 May 2019

Induction of alarmin S100A8/A9 mediates activation of aberrant neutrophils in the pathogenesis of COVID-19

scientific article published on 26 December 2020

Induction of neutralizing antibodies to influenza A virus H7N9 by inactivated whole virus in mice and nonhuman primates

scientific article published on 16 April 2014

Infection of SARS-CoV on juvenile and adult Brandt's voleMicrotus brandtii

scientific article published on 01 January 2005

Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion

scientific article published on 30 March 2020

Inhibition of SARS-CoV-2 infection (previously 2019-nCoV) by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion

scientific article (preprint)

Interleukin-37 Ameliorates Influenza Pneumonia by Attenuating Macrophage Cytokine Production in a MAPK-Dependent Manner

scientific article published on 30 October 2019

Intranasal immunization of mice with inactivated virus and mast cell activator C48/80 elicits protective immunity against influenza H1 but not H5.

scientific article

Intranasal immunization with recombinant HA and mast cell activator C48/80 elicits protective immunity against 2009 pandemic H1N1 influenza in mice

scientific article (publication date: 2011)

Molecular epidemiological tracing of HIV-1 outbreaks in Hainan island of southern China

scientific article published on May 2009

Molecular tracing of sexual HIV Type 1 transmission in the southwest border of China

scientific article

Neurotropism In Vitro and Mouse Models of Severe and Mild Infection with Clinical Strains of Enterovirus 71.

scientific article published on 20 November 2017

Novel avian-origin human influenza A(H7N9) can be transmitted between ferrets via respiratory droplets.

scientific article

Potent neutralizing antibodies against SARS-CoV-2 identified by high-throughput single-cell sequencing of convalescent patients' B cells

scientific article published on 18 May 2020

Primary exposure to SARS-CoV-2 protects against reinfection in rhesus macaques

scientific article published on 02 July 2020

Protection of Rhesus Macaque from SARS-Coronavirus challenge by recombinant adenovirus vaccine

scientific article

Rapid adaptation of avian H7N9 virus in pigs

scientific article published on 14 February 2014

Rapid development of an inactivated vaccine candidate for SARS-CoV-2

scientific article published on 06 May 2020

Rapid development of an inactivated vaccine for SARS-CoV-2

scientific article published on 20 April 2020

Real-time PCR Detection Method for the Reston Subtype of the Ebola Virus

scientific article published on May 2015

Recombinant Receptor Binding Domain Protein Induces Partial Protective Immunity in Rhesus Macaques Against Middle East Respiratory Syndrome Coronavirus Challenge

scientific article

Reinfection could not occur in SARS-CoV-2 infected rhesus macaques

scientific article (preprint)

Rhesus macaques can be effectively infected with SARS-CoV-2 via ocular conjunctival route

scientific article (preprint)

The Ablation of Envelope Protein Glycosylation Enhances the Neurovirulence of ZIKV and Cell Apoptosis in Newborn Mice

scientific article published on 17 July 2021

The Pathogenicity of SARS-CoV-2 in hACE2 Transgenic Mice

scientific article published on 12 February 2020

The mouse and ferret models for studying the novel avian-origin human influenza A (H7N9) virus ⬇️

scientific article published on 08 August 2013

Transmission of H7N9 influenza virus in mice by different infective routes

scientific article

Transmission of SARS-CoV-2 via close contact and respiratory droplets among hACE2 mice

scientific article published on 23 May 2020

Treatment With Lopinavir/Ritonavir or Interferon-β1b Improves Outcome of MERS-CoV Infection in a Nonhuman Primate Model of Common Marmoset

scientific article published on 21 July 2015

List of works by Linlin Bao

A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury

A single-amino-acid substitution in the HA protein changes the replication and pathogenicity of the 2009 pandemic A (H1N1) influenza viruses in vitro and in vivo ⬇️

Adaption of Seasonal H1N1 Influenza Virus in Mice ⬇️

An animal model of MERS produced by infection of rhesus macaques with MERS coronavirus

Antigenicity and transmissibility of a novel clade 2.3.2.1 avian influenza H5N1 virus

Challenge and polymorphism analysis of the novel A (H1N1) influenza virus to normal animals

Characterization of Two Human Monoclonal Antibodies Neutralizing Influenza A H7N9 Viruses

Characterization of an H9N2 avian influenza virus from a Fringilla montifringilla brambling in northern China

Clinical and Biological Character in Mouse Models for Middle East Respiratory Syndrome Generated by Transduction with Different Doses of DPP4 Molecule

Combinations of oseltamivir and fibrates prolong the mean survival time of mice infected with the lethal H7N9 influenza virus

Comparative pathology of rhesus macaque and common marmoset animal models with Middle East respiratory syndrome coronavirus

Correction to: The mouse and ferret models for studying the novel avian-origin human influenza A (H7N9) virus

Correction: Genomic Polymorphism of the Pandemic A (H1N1) Influenza Viruses Correlates with Viral Replication, Virulence, and Pathogenicity In Vitro and In Vivo

Determination of Influenza Virus H5N1 and H7N9 Using MASA Technology

Development of an Inactivated Vaccine Candidate, BBIBP-CorV, with Potent Protection against SARS-CoV-2

Distribution of enterovirus 71 RNA in inflammatory cells infiltrating different tissues in fatal cases of hand, foot, and mouth disease

Diverse biological characteristics and varied virulence of H7N9 from Wave 5

Enhanced protection in mice induced by immunization with inactivated whole viruses compare to spike protein of middle east respiratory syndrome coronavirus.

From SARS to MERS, Thrusting Coronaviruses into the Spotlight

Genomic Polymorphism of the Pandemic A (H1N1) Influenza Viruses Correlates with Viral Replication, Virulence, and Pathogenicity In Vitro and In Vivo ⬇️

Hemagglutinin amino acids related to receptor specificity could affect the protection efficacy of H5N1 and H7N9 avian influenza virus vaccines in mice.

Higher Immunological Protection of Pandemic 2009 H1N1 Influenza Live Virus Infection than Split Vaccine Against the Homologous Virus for Long Term Immunization in Ferret.

Highly pathogenic avian influenza H5N1 virus could partly be evacuated by pregnant BALB/c mouse during abortion or preterm delivery ⬇️

Histopathological features and distribution of EV71 antigens and SCARB2 in human fatal cases and a mouse model of enterovirus 71 infection

Human Neutralizing Monoclonal Antibody Inhibition of Middle East Respiratory Syndrome Coronavirus Replication in the Common Marmoset.

Human monoclonal antibodies targeting the haemagglutinin glycoprotein can neutralize H7N9 influenza virus.

Human-Derived A/Guangdong/Th005/2017 (H7N9) Exhibits Extremely High Replication in the Lungs of Ferrets and Is Highly Pathogenic in Chickens

Induction of alarmin S100A8/A9 mediates activation of aberrant neutrophils in the pathogenesis of COVID-19

Induction of neutralizing antibodies to influenza A virus H7N9 by inactivated whole virus in mice and nonhuman primates

Infection of SARS-CoV on juvenile and adult Brandt's voleMicrotus brandtii

Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion

Inhibition of SARS-CoV-2 infection (previously 2019-nCoV) by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion

Interleukin-37 Ameliorates Influenza Pneumonia by Attenuating Macrophage Cytokine Production in a MAPK-Dependent Manner

Intranasal immunization of mice with inactivated virus and mast cell activator C48/80 elicits protective immunity against influenza H1 but not H5.

Intranasal immunization with recombinant HA and mast cell activator C48/80 elicits protective immunity against 2009 pandemic H1N1 influenza in mice

Molecular epidemiological tracing of HIV-1 outbreaks in Hainan island of southern China

Molecular tracing of sexual HIV Type 1 transmission in the southwest border of China

Neurotropism In Vitro and Mouse Models of Severe and Mild Infection with Clinical Strains of Enterovirus 71.

Novel avian-origin human influenza A(H7N9) can be transmitted between ferrets via respiratory droplets.

Potent neutralizing antibodies against SARS-CoV-2 identified by high-throughput single-cell sequencing of convalescent patients' B cells

Primary exposure to SARS-CoV-2 protects against reinfection in rhesus macaques

Protection of Rhesus Macaque from SARS-Coronavirus challenge by recombinant adenovirus vaccine

Rapid adaptation of avian H7N9 virus in pigs

Rapid development of an inactivated vaccine candidate for SARS-CoV-2

Rapid development of an inactivated vaccine for SARS-CoV-2

Real-time PCR Detection Method for the Reston Subtype of the Ebola Virus

Recombinant Receptor Binding Domain Protein Induces Partial Protective Immunity in Rhesus Macaques Against Middle East Respiratory Syndrome Coronavirus Challenge

Reinfection could not occur in SARS-CoV-2 infected rhesus macaques

Rhesus macaques can be effectively infected with SARS-CoV-2 via ocular conjunctival route

The Ablation of Envelope Protein Glycosylation Enhances the Neurovirulence of ZIKV and Cell Apoptosis in Newborn Mice

The Pathogenicity of SARS-CoV-2 in hACE2 Transgenic Mice

The mouse and ferret models for studying the novel avian-origin human influenza A (H7N9) virus ⬇️

Transmission of H7N9 influenza virus in mice by different infective routes

Transmission of SARS-CoV-2 via close contact and respiratory droplets among hACE2 mice

Treatment With Lopinavir/Ritonavir or Interferon-β1b Improves Outcome of MERS-CoV Infection in a Nonhuman Primate Model of Common Marmoset

[Histopathological changes in EV71-infected mouse model:a transmission electron microscopic study]