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List of works by Ronald M. Evans

2003 Keio Medical Science Prize commemorative lecture. PPARs and the complex journey to obesity

scientific article published in June 2004

30 YEARS OF THE MINERALOCORTICOID RECEPTOR: Short reflections on the discovery of the mineralocorticoid receptor

scientific article published in July 2017

4-Oxoretinol, a new natural ligand and transactivator of the retinoic acid receptors.

scientific article published on May 1996

9-cis retinoic acid is a high affinity ligand for the retinoid X receptor

scientific article published on January 24, 1992

A Gpr120-selective agonist improves insulin resistance and chronic inflammation in obese mice

scientific article published on 6 July 2014

A Nuclear Receptor Atlas: 3T3-L1 adipogenesis.

scientific article published on 28 July 2005

A Nuclear Receptor Atlas: macrophage activation

scientific article published on 28 July 2005

A PML–PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance

scientific article published in September 2012

A PPAR gamma-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis

scientific article (publication date: 2001)

A PPARγ-FGF1 axis is required for adaptive adipose remodelling and metabolic homeostasis

scientific article

A Stromal Lysolipid-Autotaxin Signaling Axis Promotes Pancreatic Tumor Progression

scientific article published on 05 March 2019

A Transcriptional Switch Mediated by Cofactor Methylation ⬇️

scientific article published on November 8, 2001

A Universal Gut-Microbiome-Derived Signature Predicts Cirrhosis

scientific article published on 24 June 2020

A c-erb-A binding site in rat growth hormone gene mediates trans-activation by thyroid hormone.

scientific article published on October 1987

A chemical, genetic, and structural analysis of the nuclear bile acid receptor FXR

scientific article (publication date: April 2003)

A direct repeat in the cellular retinol-binding protein type II gene confers differential regulation by RXR and RAR

scientific article

A dynamic role for HDAC7 in MEF2-mediated muscle differentiation.

scientific article published on 8 March 2001

A framework for advancing our understanding of cancer-associated fibroblasts

scientific article published on 24 January 2020

A gut microbiome signature for cirrhosis due to nonalcoholic fatty liver disease

scientific article published on 29 March 2019

A histone deacetylase corepressor complex regulates the Notch signal transduction pathway

scientific article

A methylation-mediator complex in hormone signaling

scientific article published on 16 January 2004

A mutated retinoic acid receptor-alpha exhibiting dominant-negative activity alters the lineage development of a multipotent hematopoietic cell line

scientific article published on December 1, 1992

A novel constitutive androstane receptor-mediated and CYP3A-independent pathway of bile acid detoxification

scientific article published in February 2004

A novel macromolecular structure is a target of the promyelocyte-retinoic acid receptor oncoprotein

scientific article (publication date: 28 January 1994)

A novel pregnane X receptor-mediated and sterol regulatory element-binding protein-independent lipogenic pathway

scientific article

A nuclear receptor-mediated xenobiotic response and its implication in drug metabolism and host protection.

scientific article

A nuclear strike against Listeria--the evolving life of LXR.

scientific article published in October 2004

A peroxisome proliferator-activated receptor-δ agonist provides neuroprotection in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson’s disease ⬇️

scientific article published on March 7, 2013

A retinoic acid-triggered cascade of HOXB1 gene activation

scientific journal article

A role for adult TLX-positive neural stem cells in learning and behaviour

scientific article

A single domain of the estrogen receptor confers deoxyribonucleic acid binding and transcriptional activation of the rat prolactin gene.

scientific article published in January 1988

A subcutaneous adipose tissue-liver signalling axis controls hepatic gluconeogenesis

scientific article

A super-enhancer-regulated RNA-binding protein cascade drives pancreatic cancer

scientific article published on 6 September 2023

A transcriptional basis for physiology

scientific article published in October 2004

A transcriptional co-repressor that interacts with nuclear hormone receptors

scientific article

A vitamin D receptor/SMAD genomic circuit gates hepatic fibrotic response

scientific article published on April 2013

AMPK and PPARdelta agonists are exercise mimetics

scientific article

AMPK and PPARδ Agonists Are Exercise Mimetics

AMPK regulates the circadian clock by cryptochrome phosphorylation and degradation

scientific journal article

Acquisition of oncogenic potential by RAR chimeras in acute promyelocytic leukemia through formation of homodimers.

scientific article published on May 2000

Activators of the nuclear receptor PPARγ enhance colon polyp formation ⬇️

scientific article published on September 1, 1998

Activin and Its Receptors during Gastrulation and the Later Phases of Mesoderm Development in the Chick Embryo ⬇️

scientific article published on November 1, 1995

Adenovirus replication is coupled with the dynamic properties of the PML nuclear structure.

scientific article published on January 1996

Adipose-specific peroxisome proliferator-activated receptor gamma knockout causes insulin resistance in fat and liver but not in muscle

scientific article

Alleviation of neuronal energy deficiency by mTOR inhibition as a treatment for mitochondria-related neurodegeneration

scientific article (publication date: 23 March 2016)

Alteration of a single amino acid in peroxisome proliferator-activated receptor-alpha (PPAR alpha) generates a PPAR delta phenotype

scientific article

Altered expression of the calcitonin gene associated with RNA polymorphism.

scientific article

Alternative RNA processing in calcitonin gene expression generates mRNAs encoding different polypeptide products

scientific article

An S116R Phosphorylation Site Mutation in Human Fibroblast Growth Factor-1 Differentially Affects Mitogenic and Glucose-Lowering Activities

scientific article

An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids.

scholarly article

An inhibitor of the protein kinases TBK1 and IKK-ɛ improves obesity-related metabolic dysfunctions in mice

scientific article

Anatomical profiling of nuclear receptor expression reveals a hierarchical transcriptional network

scientific article

Androstane metabolites bind to and deactivate the nuclear receptor CAR-beta

scientific article

Arsenic decreases RXRα-dependent transcription of CYP3A and suppresses immune regulators in hepatocytes

scientific article

Arsenite decreases CYP3A23 induction in cultured rat hepatocytes by transcriptional and translational mechanisms

scientific article published in December 2005

Arsenite decreases CYP3A4 and RXRalpha in primary human hepatocytes

scientific article published on 15 April 2005

Association of CBP/p300 acetylase and thymine DNA glycosylase links DNA repair and transcription

scientific article (publication date: February 2002)

Ataxin 1, a SCA1 neurodegenerative disorder protein, is functionally linked to the silencing mediator of retinoid and thyroid hormone receptors

scientific article

Atrial-like phenotype is associated with embryonic ventricular failure in retinoid X receptor alpha -/- mice.

scientific article

Author Correction: Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity

scientific article published in Nature

Autocrine FGF1 signaling promotes glucose uptake in adipocytes

scientific article published on 4 October 2022

BRD4 is a novel therapeutic target for liver fibrosis

scientific article

BRD9 regulates interferon-stimulated genes during macrophage activation via cooperation with BET protein BRD4

scientific article published on 30 December 2021

BXR, an embryonic orphan nuclear receptor activated by a novel class of endogenous benzoate metabolites.

scientific article

Barx2 and Pax7 Regulate Axin2 Expression in Myoblasts by Interaction with β-Catenin and Chromatin Remodelling

scientific article

Barx2 and Pax7 have antagonistic functions in regulation of wnt signaling and satellite cell differentiation

scientific article

Base Sequence Complexity of 35S Avian Myeloblastosis Virus RNA Determined by Molecular Hybridization Kinetics ⬇️

scientific article published on January 1, 1975

Bcl-6 and NF-kappaB cistromes mediate opposing regulation of the innate immune response.

scientific article published on 24 November 2010

Benefit of farnesoid X receptor inhibition in obstructive cholestasis

scholarly article

Bile Acid Analog Intercepts Liver Fibrosis

article published in 2016

Bone marrow NR4A expression is not a dominant factor in the development of atherosclerosis or macrophage polarization in mice

scientific article published on 3 January 2013

CRY1/2 Selectively Repress PPARδ and Limit Exercise Capacity.

scientific article

Calcipotriol Targets LRP6 to Inhibit Wnt Signaling in Pancreatic Cancer

scientific article

Calcitonin/calcitonin gene-related peptide transcription unit: tissue-specific expression involves selective use of alternative polyadenylation sites.

scientific article published on October 1984

Cardiac peroxisome proliferator-activated receptor γ is essential in protecting cardiomyocytes from oxidative damage

scientific article published on 04 July 2007

Cardiomyocyte-restricted peroxisome proliferator-activated receptor-delta deletion perturbs myocardial fatty acid oxidation and leads to cardiomyopathy

scientific article published on 10 October 2004

Catecholamines suppress fatty acid re-esterification and increase oxidation in white adipocytes via STAT3

scientific article published on 08 June 2020

Characterization of DNA binding and retinoic acid binding properties of retinoic acid receptor ⬇️

scientific article published on May 1, 1991

Characterization of distinct subpopulations of hepatic macrophages in HFD/obese mice

scientific article published on 14 October 2014

Chromosomal localization of the human retinoid X receptors

scientific journal article

Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML ⬇️

scientific article published on August 23, 1991

Chronicle of a discovery: the retinoic acid receptor

Chronicle of a discovery: the retinoic acid receptor

scientific article published in November 2022

Circadian Amplitude Regulation via FBXW7-Targeted REV-ERBα Degradation

scientific article published on 26 May 2016

Circadian clock cryptochrome proteins regulate autoimmunity

scientific article published on 6 November 2017

Circadian repressors CRY1 and CRY2 broadly interact with nuclear receptors and modulate transcriptional activity.

scientific article published on 27 July 2017

Cistromic and genetic evidence that the vitamin D receptor mediates susceptibility to latitude-dependent autoimmune diseases.

scientific article published on 17 March 2016

Class IIa histone deacetylases are hormone-activated regulators of FOXO and mammalian glucose homeostasis

scientific article published on May 2011

Co-repressor release but not ligand binding is a prerequisite for transcription activation by human retinoid acid receptor alpha ligand-binding domain

scientific article published on 4 December 2002

Coexpression of nuclear receptor partners increases their solubility and biological activities.

scientific article

Coincidence of the promoter and capped 5' terminus of RNA from the adenovirus 2 major late transcription unit.

scientific article

Colocalization of DNA-binding and transcriptional activation functions in the human glucocorticoid receptor

scientific article published on 01 April 1987

Colon cancer checks in when bile acids check out: the bile acid-nuclear receptor axis in colon cancer

scientific article published on 17 December 2021

Compound mutants for retinoic acid receptor (RAR) beta and RAR alpha 1 reveal developmental functions for multiple RAR beta isoforms.

scientific article published in March 1996

Construction and identification by positive hybridization-translation of a bacterial plasmid containing a rat growth hormone structural gene sequence ⬇️

scientific article published on June 1, 1978

Control of steroid, heme, and carcinogen metabolism by nuclear pregnane X receptor and constitutive androstane receptor

scientific article

Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors

scientific article

Corepressor SMRT binds the BTB/POZ repressing domain of the LAZ3/BCL6 oncoprotein

scientific article published on September 1997

Corepressor SMRT is required to maintain Hox transcriptional memory during somitogenesis

article published in the Proceedings of the National Academy of Sciences of the United States of America

Corepressor SMRT promotes oxidative phosphorylation in adipose tissue and protects against diet-induced obesity and insulin resistance

scientific article

Critical roles of the p160 transcriptional coactivators p/CIP and SRC-1 in energy balance

scientific article

Cross-coupling of signal transduction pathways: zinc finger meets leucine zipper.

scientific article

Cryptochromes mediate rhythmic repression of the glucocorticoid receptor

scientific article

Cyclic AMP regulation of eukaryotic gene transcription by two discrete molecular mechanisms.

scientific article published in July 1985

Cytoplasmic catalytic subunit of protein kinase A mediates cross-repression by NF-kappa B and the glucocorticoid receptor.

scientific article

DSF nuclear receptor acts as a repressor in culture and in vivo

scientific article

Daily running enhances molecular and physiological circadian rhythms in skeletal muscle

scientific article published in 2022

Deficiency of PPARbeta/delta in the epidermis results in defective cutaneous permeability barrier homeostasis and increased inflammation

scientific article published on 23 August 2007

Dependence of hippocampal function on ERRγ-regulated mitochondrial metabolism

scientific article

Depletion of fat-resident Treg cells prevents age-associated insulin resistance

scientific article

Determinants for selective RAR and TR recognition of direct repeat HREs.

scientific article

Development of ecdysone-regulated lentiviral vectors

scientific article

Differences between the integration of avian myeloblastosis virus DNA in leukemic cells and of endogenous viral DNA in normal chicken cells.

scientific article published on August 1974

Differential activation of adipogenesis by multiple PPAR isoforms.

scientific article published on April 1996

Differential expression and activation of a family of murine peroxisome proliferator-activated receptors

scientific journal article

Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors

scientific article (publication date: 28 June 1991)

Discovery and optimization of non-steroidal FXR agonists from natural product-like libraries

scientific article

Discrete cis-active genomic sequences dictate the pituitary cell type-specific expression of rat prolactin and growth hormone genes.

scientific article

Disease tolerance mediated by microbiome E. coli involves inflammasome and IGF-1 signaling

scientific article published in October 2015

Domain structure of human glucocorticoid receptor and its relationship to the v-erb-A oncogene product.

scientific article published in December 1985

Dramatic Pituitary Hyperplasia in Transgenic Mice Expressing a Human Growth Hormone-Releasing Factor Gene

article

Drosophila ultraspiracle modulates ecdysone receptor function via heterodimer formation

scientific article published on October 2, 1992

E47 modulates hepatic glucocorticoid action

scientific article published in Nature Communications

ERRgamma directs and maintains the transition to oxidative metabolism in the postnatal heart

scientific article published in July 2007

ERRgamma regulates cardiac, gastric, and renal potassium homeostasis

scientific article

ERRs Mediate a Metabolic Switch Required for Somatic Cell Reprogramming to Pluripotency

scientific article published on 9 April 2015

ERRγ Is Required for the Metabolic Maturation of Therapeutically Functional Glucose-Responsive β Cells

scientific article published on April 2016

ERRγ Preserves Brown Fat Innate Thermogenic Activity.

scientific article published in March 2018

ERRγ Promotes Angiogenesis, Mitochondrial Biogenesis, and Oxidative Remodeling in PGC1α/β-Deficient Muscle

Ecdysone-inducible gene expression in mammalian cells and transgenic mice.

scientific article published on April 1996

Editorial overview

Effective treatment of steatosis and steatohepatitis by fibroblast growth factor 1 in mouse models of nonalcoholic fatty liver disease

scientific article published on 8 February 2016

Effects of naturally occurring coumarins on hepatic drug-metabolizing enzymes in mice

scientific article published on 15 July 2008

Effects of peroxisome proliferator-activated receptor delta on placentation, adiposity, and colorectal cancer

scientific article

Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer

scientific article (publication date: 18 September 2014)

Energy deprivation and a deficiency in downstream metabolic target genes during the onset of embryonic heart failure in RXRα−/− embryos ⬇️

scientific article published on February 1, 1998

Epigenetic codes of PPARγ in metabolic disease

scientific article published on 19 May 2011

Erratum: Corrigendum: Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer

scientific article published in Nature

Erratum: Corrigendum: Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells

scientific article published in Nature

Erratum: Corrigendum: ROR-γ drives androgen receptor expression and represents a therapeutic target in castration-resistant prostate cancer

scholarly article published in Nature Medicine

Erratum: Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion

scientific article published on 05 October 2016

Erratum: Spatial and temporal expression of the retinoic acid receptor in the regenerating amphibian limb

scientific article published in Nature

Esrrg functions in early branch generation of the ureteric bud and is essential for normal development of the renal papilla

scientific article published on 6 December 2010

Estrogen-related receptor α (ERRα) and ERRγ are essential coordinators of cardiac metabolism and function

scientific article

Evidence for orphan nuclear receptor TR4 in the etiology of Cushing disease

scientific article published on 7 May 2013

Exercise Mimetics: Impact on Health and Performance

scientific article

Exercise and PGC-1α-independent synchronization of type I muscle metabolism and vasculature by ERRγ.

scientific article published on March 2011

Expression Cloning of Human EGF Receptor Complementary DNA: Gene Amplification and Three Related Messenger RNA Products in A431 Cells ⬇️

scientific article published on May 25, 1984

Expression and function of orphan nuclear receptor TLX in adult neural stem cells

scientific journal article

Expression of human growth hormone-releasing factor in transgenic mice results in increased somatic growth.

scientific article published in May 1985

Extrahepatic cancer suppresses nuclear receptor-regulated drug metabolism

scientific article

FGF1 - a new weapon to control type 2 diabetes mellitus

scientific article published on 30 June 2017

FXR Regulates Intestinal Cancer Stem Cell Proliferation

scientific article published on 01 February 2019

FXR mediates ILC-intrinsic responses to intestinal inflammation

scientific article published on 20 December 2022

Farnesoid X Receptor an Emerging Target to Combat Obesity

scientific article

Feeder-dependent and feeder-independent iPS cell derivation from human and mouse adipose stem cells

scientific article

Fibroblast Growth Factor Signaling in Metabolic Regulation

scientific article

Forced retinoic acid receptor alpha homodimers prime mice for APL-like leukemia

scientific article published on February 2006

Functional ecdysone receptor is the product of EcR and Ultraspiracle genes.

scientific article published on December 1993

Genetic analysis of the retinoid signal.

scientific article published on June 1996

Genetic deficiency in Pparg does not alter development of experimental prostate cancer

scientific article published on 7 September 2003

Genetic profiling defines the xenobiotic gene network controlled by the nuclear receptor pregnane X receptor

scientific article published on 27 March 2003

Genome-wide orchestration of cardiac functions by the orphan nuclear receptors ERRalpha and gamma

scientific article published in May 2007

Global chemical effects of the microbiome include new bile-acid conjugations

scientific article published on 26 February 2020

Glucocorticoid and thyroid hormones transcriptionally regulate growth hormone gene expression

scientific article

Glycogen metabolism links glucose homeostasis to thermogenesis in adipocytes

scientific article published on 27 October 2021

Growth differentiation factor 15 is a myomitokine governing systemic energy homeostasis.

scientific article published on 16 December 2016

Gut metagenome-derived signature predicts hepatic decompensation and mortality in NAFLD-related cirrhosis

scientific article published in November 2022

Hepatic Nuclear Receptor Expression Associates with Features of Histology in Pediatric Nonalcoholic Fatty Liver Disease

scientific article published on 27 September 2018

Hepatic actions of vitamin D receptor ligands: a sunshine option for chronic liver disease?

scientific article

Hepatic protein kinase C: Translocation stimulated by prolactin and partial hepatectomy

scientific article published on 01 December 1987

High-fat diet and FGF21 cooperatively promote aerobic thermogenesis in mtDNA mutator mice

scientific article published on 29 June 2015

Homogeneity and complexity of avian oncornavirus proviral DNA determined by molecular hybridization ⬇️

scientific article published on March 1, 1977

Hormonal regulation of the nuclear localization signals of the human glucocorticosteroid receptor

scientific article

Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells

scientific article

Human Daxx regulates Fas-induced apoptosis from nuclear PML oncogenic domains (PODs).

scientific article

Human and mouse adipose-derived cells support feeder-independent induction of pluripotent stem cells

scientific article

Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta

scientific article

Identification of a nuclear domain with deacetylase activity.

scientific article published on September 2000

Identification of a nuclear receptor that is activated by farnesol metabolites

scientific article

Identification of human glucocorticoid receptor complementary DNA clones by epitope selection

scholarly article

Identification of receptors for retinoids as members of the steroid and thyroid hormone receptor family.

scientific article

Identification of three novel natural product compounds that activate PXR and CAR and inhibit inflammation

scientific article published on 30 July 2013

Imaging Fibrosis and Separating Collagens using Second Harmonic Generation and Phasor Approach to Fluorescence Lifetime Imaging

scientific article published on 21 August 2015

Immune-evasive human islet-like organoids ameliorate diabetes

scientific article published on 19 August 2020

Inducible gene expression in mammalian cells and transgenic mice ⬇️

scientific article published on October 1, 1997

Infectious and Selectable Retrovirus Containing an Inducible Rat Growth Hormone Minigene ⬇️

scientific article published on September 7, 1984

Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity

scientific article

Inflammation-sensitive super enhancers form domains of coordinately regulated enhancer RNAs

scientific article

Inhibin A-subunit cDNAs from porcine ovary and human placenta

scientific article

Inhibition of IKKɛ and TBK1 Improves Glucose Control in a Subset of Patients with Type 2 Diabetes

scientific article published in July 2017

Insights into negative regulation by the glucocorticoid receptor from genome-wide profiling of inflammatory cistromes

scientific article published on 15 November 2012

Interaction of the Ubc9 human homologue with c-Jun and with the glucocorticoid receptor

scientific article

Interactions between hepatic Mrp4 and Sult2a as revealed by the constitutive androstane receptor and Mrp4 knockout mice

scientific article published on 05 March 2004

Interactions between the retinoid X receptor and a conserved region of the TATA-binding protein mediate hormone-dependent transactivation

scientific article

International Union of Pharmacology. LX. Retinoic acid receptors

scientific article

International Union of Pharmacology. LXIII. Retinoid X receptors

scientific article

Interorgan crosstalk in pancreatic islet function and pathology

scientific article published in March 2022

Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance

scientific article

Intestinal NCoR1, a regulator of epithelial cell maturation, controls neonatal hyperbilirubinemia

scientific article published on 6 February 2017

Intestinal PPARδ protects against diet-induced obesity, insulin resistance and dyslipidemia

scientific article published on 12 April 2017

Introduction of rat growth hormone gene into mouse fibroblasts via a retroviral DNA vector: expression and regulation ⬇️

scientific article published on April 1, 1982

Isolation and characterization of mammalian HDAC10, a novel histone deacetylase

scientific journal article

Journal of Molecular Endocrinology 25th anniversary special issue

scientific article published on 26 November 2013

Ketogenic diet and chemotherapy combine to disrupt pancreatic cancer metabolism and growth

scientific article published in February 2022

LXR, a nuclear receptor that defines a distinct retinoid response pathway

scientific article

Laser microbeam abalation of GFP-labeled nuclear organelles in a living cell.

Legacy: a tribute to Terri Grodzicker of Genes & Development

scientific article published in January 2023

Let's Raise a Glass to Sydney: In Memoriam (1927-2019)

scholarly article

Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet

scientific article published on 21 November 2011

Ligand-Dependent Corepressor (LCoR) Is A Rexinoid-Inhibited PPARγ-RXRα Coactivator

scientific article published on 20 February 2018

Ligation independent cloning irrespective of restriction site compatibility.

scientific article

Liver Cancer Checks in When Bile Acid Clocks Out.

scientific article

Localization of nascent RNA and CREB binding protein with the PML-containing nuclear body.

scientific article

Loss of Transcriptional Repression by BCL6 Confers Insulin Sensitivity in the Setting of Obesity

scientific article published on 01 December 2018

Lymphoma regression induced by ganciclovir in mice bearing a herpes thymidine kinase transgene.

scientific article published in January 1990

METABOLISM. The quest to burn fat, effortlessly and safely.

scientific article published in August 2016

Maternal PPAR gamma protects nursing neonates by suppressing the production of inflammatory milk

scientific article published on 24 July 2007

Mechanism of corepressor binding and release from nuclear hormone receptors.

scientific article

Mechanisms of vascular dysfunction in mice with endothelium-specific deletion of the PPAR-δ gene

scientific article published on 31 January 2014

Metabolic Messengers: fibroblast growth factor 1

scientific article published on 9 June 2022

Metabolic Regulation by Nuclear Receptors

Metabolic and Organelle Morphology Defects in Mice and Human Patients Define Spinocerebellar Ataxia Type 7 as a Mitochondrial Disease

Metabolic control of regulatory T cell (Treg) survival and function by Lkb1.

scientific article published on 6 November 2017

Metabolic crosstalk: molecular links between glycogen and lipid metabolism in obesity

scientific article

Metabolism and cancer in La Jolla

scientific article

Metabolism: Tick, tock, a beta-cell clock

scientific article published on July 2010

Metformin-mediated Bambi expression in hepatic stellate cells induces prosurvival Wnt/β-catenin signaling

scientific article published on 9 March 2012

Methylome, transcriptome, and PPAR(γ) cistrome analyses reveal two epigenetic transitions in fat cells

scientific article

Minireview: Evolution of NURSA, the Nuclear Receptor Signaling Atlas

scientific article published on 07 May 2009

Minireview: lipid metabolism, metabolic diseases, and peroxisome proliferator-activated receptors

scientific article

Modulation of the intestinal bile acid-FXR-FGF15 axis improves alcoholic liver disease in mice.

scientific article published on 21 November 2017

Molecular genetics of acute promyelocytic leukemia.

scientific article

Monomeric complex of human orphan estrogen related receptor-2 with DNA: a pseudo-dimer interface mediates extended half-site recognition

scientific article

Multiple retinoid-responsive receptors in a single cell: families of retinoid "X" receptors and retinoic acid receptors in the Xenopus egg ⬇️

scientific article (publication date: 15 March 1992)

Muscle-specific Pparg deletion causes insulin resistance

scientific journal article

Mutual synergistic folding in recruitment of CBP/p300 by p160 nuclear receptor coactivators

scientific article

NCoR1 is a conserved physiological modulator of muscle mass and oxidative function

scientific article

NCoR1 restrains thymic negative selection by repressing Bim expression to spare thymocytes undergoing positive selection.

scientific article published on 16 October 2017

NMR spectroscopic studies of the DNA-binding domain of the monomer-binding nuclear orphan receptor, human estrogen related receptor-2. The carboxyl-terminal extension to the zinc-finger region is unstructured in the free form of the protein.

scientific article published on July 1997

Neural basis of opioid-induced respiratory depression and its rescue

scientific article published on 8 June 2021

Neuron-specific alternative RNA processing in neuroendocrine gene expression

article

Neutralization of Oxidized Phospholipids Ameliorates Non-alcoholic Steatohepatitis

scientific article published on 21 November 2019

Niche-Specific Reprogramming of Epigenetic Landscapes Drives Myeloid Cell Diversity in Nonalcoholic Steatohepatitis

scientific article published on 28 April 2020

Normal development and growth of mice carrying a targeted disruption of the alpha 1 retinoic acid receptor gene

scientific article

Nuclear Receptors and AMPK: Resetting Metabolism ⬇️

scientific article published on January 1, 2011

Nuclear Receptors, RXR, and the Big Bang

scientific article

Nuclear hormone receptors activate direct, inverted, and everted repeats.

scientific article published on June 1995

Nuclear receptor ERR alpha and coactivator PGC-1 beta are effectors of IFN-gamma-induced host defense

scientific article published in August 2007

Nuclear receptor TLX prevents retinal dystrophy and recruits the corepressor atrophin1

scientific journal article

Nuclear receptor corepressor SMRT regulates mitochondrial oxidative metabolism and mediates aging-related metabolic deterioration

scientific article

Nuclear receptors and AMPK: can exercise mimetics cure diabetes?

scientific article

Nuclear receptors and metabolism: from feast to famine

scientific article published on 12 March 2014

Nuclear receptors as modulators of the tumor microenvironment

scientific article

Nuclear receptors constitutive androstane receptor and pregnane X receptor ameliorate cholestatic liver injury

scientific article

Nuclear receptors in Sicily: all in the famiglia.

scientific article published on August 1997

Nuclear receptors rock around the clock

scientific article

Nuclear receptors, metabolism, and the circadian clock.

scientific article published on January 2007

Nuclear receptors: decoding metabolic disease

scientific article

O-GlcNAc transferase is involved in glucocorticoid receptor-mediated transrepression

scientific article published on 27 February 2012

Oleic acid regulates hippocampal neurogenesis as a TLX ligand

scientific article published on 12 April 2022

Oligonucleotides in heterogeneous nuclear RNA: similarity of inverted repeats and RNA from repetitious DNA sites

scientific article published on 11 July 1978

Orphan nuclear receptor TLX activates Wnt/beta-catenin signalling to stimulate neural stem cell proliferation and self-renewal

scientific article

Orphan nuclear receptor TLX recruits histone deacetylases to repress transcription and regulate neural stem cell proliferation

scientific article

Orphan nuclear receptors--new ligands and new possibilities.

scientific article

Orphan nuclear receptors: the exotics of xenobiotics.

scientific article

Oxidized LDL Regulates Macrophage Gene Expression through Ligand Activation of PPARγ ⬇️

scientific article published on April 17, 1998

PARP-1 determines specificity in a retinoid signaling pathway via direct modulation of mediator

scientific article (publication date: April 2005)

PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3.

scientific article published on 25 April 2004

PGC-1beta controls mitochondrial metabolism to modulate circadian activity, adaptive thermogenesis, and hepatic steatosis

scholarly article

PGC1beta mediates PPARgamma activation of osteoclastogenesis and rosiglitazone-induced bone loss

scientific article

PGC1β Mediates PPARγ Activation of Osteoclastogenesis and Rosiglitazone-Induced Bone Loss

PHGDH preserves one-carbon cycle to confer metabolic plasticity in chemoresistant gastric cancer during nutrient stress

scientific article published on 23 May 2023

PIDDosome-SCAP crosstalk controls high-fructose-diet-dependent transition from simple steatosis to steatohepatitis

scientific article published in October 2022

PPAR delta: a dagger in the heart of the metabolic syndrome

scientific article

PPAR gamma is required for placental, cardiac, and adipose tissue development

scientific article (publication date: October 1999)

PPAR gamma signaling exacerbates mammary gland tumor development

scientific article published on March 2004

PPAR-gamma regulates osteoclastogenesis in mice

scientific article

PPARdelta is a very low-density lipoprotein sensor in macrophages

scientific article

PPARdelta regulates glucose metabolism and insulin sensitivity

scientific article

PPARdelta regulates multiple proinflammatory pathways to suppress atherosclerosis

scholarly article

PPARdelta-mediated antiinflammatory mechanisms inhibit angiotensin II-accelerated atherosclerosis

scientific article

PPARgamma activation in adipocytes is sufficient for systemic insulin sensitization

scientific article published on 16 December 2009

PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL

scientific article

PPARs and ERRs: molecular mediators of mitochondrial metabolism

scientific article published on 06 December 2014

PPARs and LXRs: atherosclerosis goes nuclear

scientific article published on May 2004

PPARs and the complex journey to obesity

scientific article (publication date: April 2004)

PPARγ signaling and metabolism: the good, the bad and the future

scientific article published on 07 May 2013

PPARδ Promotes Running Endurance by Preserving Glucose

scientific article (publication date: May 2017)

PPARδ activation by bexarotene promotes neuroprotection by restoring bioenergetic and quality control homeostasis

scientific article published in December 2017

PPARδ activation promotes stratum corneum formation and epidermal permeability barrier development during late gestation

scientific journal article

PPARδ preserves a high resistance to fatigue in the mouse medial gastrocnemius after spinal cord transection

scientific article

Packing, specificity, and mutability at the binding interface between the p160 coactivator and CREB-binding protein

scientific article

Paired microbiome and metabolome analyses associate bile acid changes with colorectal cancer progression

scientific article published on 29 August 2023

Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion.

scientific article published on 10 August 2016

Peroxisome proliferator-activated receptor delta promotes very low-density lipoprotein-derived fatty acid catabolism in the macrophage

scholarly article

Peroxisome proliferator-activated receptor gamma controls Muc1 transcription in trophoblasts

scientific article published on December 2004

Peroxisome proliferator-activated receptor-gamma in macrophage lipid homeostasis

scientific article

Peroxisome-Proliferator-Activated Receptor δ Activates Fat Metabolism to Prevent Obesity ⬇️

scientific article (publication date: 18 April 2003)

Pharmaceutical use of mouse models humanized for the xenobiotic receptor

scientific article

Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance

scientific article

Phosphorylation of CREB at Ser-133 induces complex formation with CREB-binding protein via a direct mechanism

scientific article

Phosphorylation of the nuclear receptor corepressor 1 by protein kinase B switches its corepressor targets in the liver in mice

scientific article

Pituitary hyperplasia induced by ectopic expression of nerve growth factor

scientific article published on April 1992

Pitx2 determines left-right asymmetry of internal organs in vertebrates.

scientific article

Polypeptide hormone regulation of gene transcription: specific 5' genomic sequences are required for epidermal growth factor and phorbol ester regulation of prolactin gene expression ⬇️

scientific article published on May 1, 1984

Positive Reinforcing Mechanisms between GPR120 and PPARγ Modulate Insulin Sensitivity

scientific article published on 10 May 2020

Preface

scientific article published on 07 October 2009

Pregnane X receptor prevents hepatorenal toxicity from cholesterol metabolites

scientific article

Pregnane-x-receptor controls hepatic glucuronidation during pregnancy and neonatal development in humanized UGT1 mice

scientific article

Premature termination during adenovirus transcription ⬇️

scientific article published on March 22, 1979

Primary structure and expression of a functional human glucocorticoid receptor cDNA

scientific article

Production of a novel neuropeptide encoded by the calcitonin gene via tissue-specific RNA processing

scientific article

Production of mRNA in Chinese hamster cells: relationship of the rate of synthesis to the cytoplasmic concentration of nine specific mRNA sequences

scientific article published on August 1, 1979

Protection from liver fibrosis by a peroxisome proliferator-activated receptor δ agonist

scientific article

Protein kinase C phosphorylation at Thr 654 of the unoccupied EGF receptor and EGF binding regulate functional receptor loss by independent mechanisms

scientific article published in March 1986

Quantitative and Qualitative Differences in DNA Complementary to Avian Myeloblastosis Virus between Normal and Leukemic Chicken Cells ⬇️

scientific article published on January 1, 1975

RANK ligand converts the NCoR/HDAC3 co-repressor to a PGC1β- and RNA-dependent co-activator of osteoclast gene expression

scientific article published in October 2023

RNA Processing Regulation of Neuroendorcrine Gene Expression ⬇️

scientific article published on January 1, 1982

ROR-γ drives androgen receptor expression and represents a therapeutic target in castration-resistant prostate cancer

scientific article published on 28 March 2016

RORγ is a targetable master regulator of cholesterol biosynthesis in a cancer subtype

scientific article published on 11 October 2019

RXR alpha deficiency confers genetic susceptibility for aortic sac, conotruncal, atrioventricular cushion, and ventricular muscle defects in mice.

scientific article published on September 1996

RXR alpha mutant mice establish a genetic basis for vitamin A signaling in heart morphogenesis.

scientific article published in May 1994

Rat growth hormone gene: intervening sequences separate the mRNA regions ⬇️

scientific article published on June 11, 1979

Rational application of macrophage-specific LXR agonists avoids the pitfalls of SREBP-induced lipogenesis

scientific article published on 30 April 2018

Re-engineering the Pancreas Tumor Microenvironment: A "Regenerative Program" Hacked

scientific article published on April 2017

Regulation of MEF2 by histone deacetylase 4- and SIRT1 deacetylase-mediated lysine modifications

scientific article

Regulation of a xenobiotic sulfonation cascade by nuclear pregnane X receptor (PXR).

scientific article

Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β

scientific article by H. Cho et al., published in March 2012

Regulation of hormone-induced histone hyperacetylation and gene activation via acetylation of an acetylase

scientific article (publication date: 3 September 1999)

Regulation of muscle fiber type and running endurance by PPARdelta

scientific article

Relationship between Drosophila gap gene tailless and a vertebrate nuclear receptor Tlx.

scientific article

Relationship between production of epidermal growth factor receptors, gene amplification, and chromosome 7 translocation in variant A431 cells

article

Reply to "PPAR-γ regulates pharmacological but not physiological or pathological osteoclast formation".

scientific article published in November 2016

Repression of retinoic acid-induced transactivation by embryonal LTR binding protein.

scientific article published on December 1994

Reprogramming pancreatic stellate cells via p53 activation: A putative target for pancreatic cancer therapy

scientific article published on 6 December 2017

Rescue of a primary myelofibrosis model by retinoid-antagonist therapy

scientific article

Research resource: Comparative nuclear receptor atlas: basal and activated peritoneal B-1 and B-2 cells

scientific article

Retinoic acid is a negative regulator of AP-1-responsive genes.

scientific article published on July 1991

Retinoic acid is required early during adult neurogenesis in the dentate gyrus

scholarly article

Retinoic acid receptors initiate induction of the cytomegalovirus enhancer in embryonal cells ⬇️

scientific article published on August 15, 1992

Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signalling ⬇️

scientific article (publication date: 30 January 1992)

Retinoid X receptor-COUP-TF interactions modulate retinoic acid signaling ⬇️

scientific article published on February 15, 1992

Retinoid receptors in development and disease

scientific article published on April 1, 1997

Retinoid-dependent pathways suppress myocardial cell hypertrophy.

scientific article

Retrofitting fat metabolism

scientific article

Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription.

scientific article published on 02 June 2013

Revascularization of ischemic skeletal muscle by estrogen-related receptor-γ.

scientific article

Reverse transcription polymerase chain reaction for the rearranged retinoic acid receptor alpha clarifies diagnosis and detects minimal residual disease in acute promyelocytic leukemia ⬇️

scientific article published on April 1, 1992

Road to exercise mimetics: targeting nuclear receptors in skeletal muscle

scientific article

Roger Guillemin (1924 to 2024): Discoverer of brain hormones that control physiology

scientific article published on 2 May 2024

Role of the histone deacetylase complex in acute promyelocytic leukaemia ⬇️

scientific article published on February 19, 1998

Role of the nuclear receptor pregnane X receptor in acetaminophen hepatotoxicity

scientific article

Rosiglitazone activation of PPARgamma suppresses fractalkine signaling

scientific article published on 22 October 2009

SMRT isoforms mediate repression and anti-repression of nuclear receptor heterodimers

scientific article published on July 1996

SMRT repression of nuclear receptors controls the adipogenic set point and metabolic homeostasis

scientific article

SMRTER, a Drosophila nuclear receptor coregulator, reveals that EcR-mediated repression is critical for development.

scientific article published on August 1999

SRF'ing around the clock

scientific article published in January 2013

SRY-box-containing gene 2 regulation of nuclear receptor tailless (Tlx) transcription in adult neural stem cells

scientific article published on 22 December 2011

STAT6 transcription factor is a facilitator of the nuclear receptor PPARγ-regulated gene expression in macrophages and dendritic cells

scientific article

SXR, a novel steroid and xenobiotic-sensing nuclear receptor

scientific article

Seven-up inhibits ultraspiracle-based signaling pathways in vitro and in vivo.

scientific article published on December 1995

Shared Mechanisms between Cardiovascular Disease and NAFLD ⬇️

scientific article published on 25 August 2022

Sharp, an inducible cofactor that integrates nuclear receptor repression and activation

scientific article

Shining Light on the COVID-19 Pandemic: A Vitamin D Receptor Checkpoint in Defense of Unregulated Wound Healing

scientific article published on 11 September 2020

Signals and Receptors

scientific article published on April 2016

Silver electroceutical technology to treat sarcopenia

scientific article published on 15 August 2023

Skeletal muscle Nur77 expression enhances oxidative metabolism and substrate utilization

scientific article

Splice commitment dictates neuron-specific alternative RNA processing in calcitonin/CGRP gene expression.

scientific article published in February 1987

Staying the Distance: Avoiding the Proteasomal Trap

Stromal cues regulate the pancreatic cancer epigenome and metabolome

scientific article published on 17 January 2017

Structural basis for specific ligation of the peroxisome proliferator-activated receptor δ.

scientific article published on 20 March 2017

Structural determinants of nuclear receptor assembly on DNA direct repeats

scientific article

Studies on Characterization of the Integration Sites of Avian RNA Tumor Virus-specific DNA ⬇️

scientific article published on January 1, 1975

Synthetic ERRα/β/γ Agonist Induces an ERRα-Dependent Acute Aerobic Exercise Response and Enhances Exercise Capacity

scientific article published on 29 March 2023

TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism

scientific article

Target acquisition and acute promyelocytic leukemia.

scientific article

Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring

scientific article published on 17 April 2019

Targeting Transcriptional and Epigenetic Reprogramming in Stromal Cells in Fibrosis and Cancer

scientific article

Targeting the pregnane X receptor in liver injury

scientific article

Terminal Differentiation of Human Breast Cancer through PPARγ ⬇️

scientific article published on February 1, 1998

Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator-activated receptor gamma and the retinoid X receptor.

scientific article

The Bcl6-SMRT/NCoR cistrome represses inflammation to attenuate atherosclerosis

scientific article published on 29 March 2012

The Definition of Transcription Units for mRNA ⬇️

scientific article published on January 1, 1978

The Drosophila retinoid X receptor homolog ultraspiracle functions in both female reproduction and eye morphogenesis ⬇️

scientific article published on June 1, 1992

The LAZ3(BCL-6) oncoprotein recruits a SMRT/mSIN3A/histone deacetylase containing complex to mediate transcriptional repression.

scientific article published on October 1998

The Nuclear Receptor Signaling Atlas: development of a functional atlas of nuclear receptors

scientific article

The PML domain of PML-RARα blocks senescence to promote leukemia

scientific article

The RXR heterodimers and orphan receptors

scientific article (publication date: 15 December 1995)

The Spt6 SH2 domain binds Ser2-P RNAPII to direct Iws1-dependent mRNA splicing and export

scientific article

The commonly used antimicrobial additive triclosan is a liver tumor promoter

scientific article

The constitutive androstane receptor and pregnane X receptor function coordinately to prevent bile acid-induced hepatotoxicity

scientific article published on 8 September 2004

The effect of neuronal conditional knock-out of peroxisome proliferator-activated receptors in the MPTP mouse model of Parkinson's disease

scientific article published on 29 May 2015

The expression of GPIHBP1, an endothelial cell binding site for lipoprotein lipase and chylomicrons, is induced by peroxisome proliferator-activated receptor-gamma

scientific article published on 11 September 2008

The germ cell nuclear factor mGCNF is expressed in the developing nervous system.

scientific article published on January 1997

The ginsenoside metabolite compound K, a novel agonist of glucocorticoid receptor, induces tolerance to endotoxin-induced lethal shock

scientific article published on 05 December 2007

The histone acetylase PCAF is a nuclear receptor coactivator.

scientific article

The initiation sites for RNA transcription in Ad2 DNA

scientific article published on November 1, 1977

The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming

scientific article published on 8 November 2011

The nuclear receptor REV-ERBα modulates Th17 cell-mediated autoimmune disease

scientific article published on 27 August 2019

The nuclear receptor superfamily: a rosetta stone for physiology

scientific article

The nuclear receptor superfamily: the second decade

scientific article (publication date: 15 December 1995)

The orphan nuclear receptor LXRalpha is positively and negatively regulated by distinct products of mevalonate metabolism

scientific article

The orphan nuclear receptor Tlx regulates Pax2 and is essential for vision

scientific journal article

The peroxisome proliferator-activated receptor delta, an integrator of transcriptional repression and nuclear receptor signaling

scientific article

The starvation hormone, fibroblast growth factor-21, extends lifespan in mice.

scientific article

The steroid and thyroid hormone receptor superfamily

scientific article

The structural basis for the specificity of retinoid-X receptor-selective agonists: new insights into the role of helix H12

scientific article

The synthesis and processing of a nuclear RNA precursor to rat pregrowth hormone messenger RNA.

scientific article

The v-erbA oncogene is a thyroid hormone receptor antagonist

scientific article published on 01 January 1989

Thyroid hormone receptor repression is linked to type I pneumocyte-associated respiratory distress syndrome

scientific journal article

Tick, tock, a high-fat clock

Timed use of cardiac glycoside protects the heart

scientific article published on 3 November 2022

Tissue damage drives co-localization of NF-κB, Smad3, and Nrf2 to direct Rev-erb sensitive wound repair in mouse macrophages

scientific article published on 27 July 2016

Tlx and Pax6 co-operate genetically to establish the pallio-subpallial boundary in the embryonic mouse telencephalon

scientific article published in March 2003

Trans-activation by thyroid hormone receptors: functional parallels with steroid hormone receptors.

scientific article

Transactivation and synergistic properties of the mineralocorticoid receptor: relationship to the glucocorticoid receptor

scientific article published on 01 April 1993

Transcriptional regulation in acute promyelocytic leukemia.

scientific article

Transcriptional regulation of the c-jun gene by retinoic acid and E1A during differentiation of F9 cells ⬇️

scientific article published on January 1, 1992

Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a.

scientific article

Transcriptional repression of atherogenic inflammation: modulation by PPARdelta

scientific article

Transgenic mice: applications to the study of the nervous system.

scientific article published on January 1988

Triclocarban mediates induction of xenobiotic metabolism through activation of the constitutive androstane receptor and the estrogen receptor alpha

scientific article published in 2012

Triptolide targets super-enhancer networks in pancreatic cancer cells and cancer-associated fibroblasts

scientific article published on 09 November 2020

Tumor suppressor protein (p)53, is a regulator of NF-kappaB repression by the glucocorticoid receptor

scientific article

Turning Up the Heat on Membrane Fluidity

article published in 2015

Two different cis-active elements transfer the transcriptional effects of both EGF and phorbol esters

scientific article

Unified neural pathways that gate affective pain and multisensory innate threat signals to the amygdala

scientific article published on 16 January 2021

Unique forms of human and mouse nuclear receptor corepressor SMRT

scientific article

Unique response pathways are established by allosteric interactions among nuclear hormone receptors

scientific article

Use of Angiotensin System Inhibitors Is Associated with Immune Activation and Longer Survival in Nonmetastatic Pancreatic Ductal Adenocarcinoma

scientific article published on 9 June 2017

Visible light reduces C. elegans longevity

scientific article published on 2 March 2018

Vitamin A deprivation results in reversible loss of hippocampal long-term synaptic plasticity

scientific article

Vitamin D Switches BAF Complexes to Protect β Cells.

scientific article published on 7 May 2018

Vitamin D receptor as an intestinal bile acid sensor

scientific article

Vitamin D receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy

scientific article

Wealth management in the gut

scientific article published in Nature

Wylie Walker Vale Jr (1941–2012) ⬇️

scientific article published on March 28, 2012

YIPF6 controls sorting of FGF21 into COPII vesicles and promotes obesity

scientific article published on 09 July 2019

Zinc accumulation in Atriplex lentiformis is driven by plant genes and the soil microbiome

scientific article published on 15 November 2023

β-Catenin is essential for differentiation of primary myoblasts via cooperation with MyoD and α-catenin

scientific article published on 19 March 2019

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