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List of works by Jacobijn Gussekloo

A Structured Process Description of a Pragmatic Implementation Project: Improving Integrated Care for Older Persons in Residential Care Homes

scientific article

A postal screener for pain and need for treatment in older persons in primary care

scientific article published on 03 October 2014

Accuracy of the 15-item geriatric depression scale (GDS-15) in a community sample of the oldest old.

scientific article published in January 2003

An Internet-based Acceptance and Commitment Therapy intervention for older adults with anxiety complaints: study protocol for a cluster randomized controlled trial

scientific article published on 17 September 2018

An individual participant data analysis of prospective cohort studies on the association between subclinical thyroid dysfunction and depressive symptoms

scientific article published on 05 November 2020

Anaemia and physical and mental health in the very old: An individual participant data meta-analysis of four longitudinal studies of ageing

scientific article published on 16 September 2020

Assessment of appropriateness of screening community-dwelling older people to prevent functional decline

scientific article

Assistive devices and community-based services among 85-year-old community-dwelling elderly in The Netherlands: ownership, use, and need for intervention

scientific article published in June 2006

Association Between Glycosylated Hemoglobin and Cardiovascular Events and Mortality in Older Adults without Diabetes Mellitus in the General Population: The Leiden 85-Plus Study

scientific article published on June 2015

Association Between Levothyroxine Treatment and Thyroid-Related Symptoms Among Adults Aged 80 Years and Older With Subclinical Hypothyroidism

scientific article published on 30 October 2019

Association between chronic diseases and disability in elderly subjects with low and high income: the Leiden 85-plus Study

scientific article published on 13 July 2005

Association between high-density lipoprotein and cognitive impairment in the oldest old.

scientific article

Association of APOE epsilon2/epsilon3/epsilon4 and promoter gene variants with dementia but not cardiovascular mortality in old age.

scientific article published in January 2002

Association of Thyroid Hormone Therapy With Quality of Life and Thyroid-Related Symptoms in Patients With Subclinical Hypothyroidism: A Systematic Review and Meta-analysis

scientific article published in The Journal of the American Medical Association

Associations of Cytomegalovirus Infection With All-Cause and Cardiovascular Mortality in Multiple Observational Cohort Studies of Older Adults

scientific article published on 10 September 2020

Associations of Elevated Antithyroperoxidase Antibodies with Thyroid Function, Survival, Functioning, and Depressive Symptoms in the Oldest Old: The Leiden 85-plus Study

scientific article published on 01 September 2019

Associations of Various Health-Ratings with Geriatric Giants, Mortality and Life Satisfaction in Older People.

scientific article

Auditory rehabilitation of older people from the general population--the Leiden 85-plus study.

scientific article

Benefits of increasing the dose of influenza vaccine in residents of long-term care facilities: a randomized placebo-controlled trial.

scientific article published in May 2009

Benzodiazepine use and risk of mortality in individuals aged 85 years or older

scientific article

Biological correlates of blood pressure variability in elderly at high risk of cardiovascular disease

scientific article published on 8 October 2014

Biomarkers versus traditional risk factors to predict cardiovascular events in very old adults: cross-validated prospective cohort study

scientific article published on 28 June 2020

Blood pressure trends and mortality: the Leiden 85-plus Study.

scientific article published in January 2013

Blood pressure variability and cardiovascular risk in the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER).

scientific article

Bone geometry in older adults with subclinical hypothyroidism upon levothyroxine therapy: A nested study within a randomized placebo controlled trial

scientific article published in 2022

Burden of cardiovascular disease across 29 countries and GPs' decision to treat hypertension in oldest-old.

scientific article published on 25 January 2018

Changes in geriatric rehabilitation: a national programme to improve quality of care. The Synergy and Innovation in Geriatric Rehabilitation study

scientific article published on October 2015

Changes in patient satisfaction related to their perceived health state during implementation of improved integrated care for older persons.

scientific article published on 16 May 2019

Chronic kidney disease in patients with diabetes mellitus type 2 or hypertension in general practice

scientific article

Clinical determinants of low handgrip strength and its decline in the oldest old: the Leiden 85-plus Study

scientific article published on 30 June 2020

Clinical relevance of a raised plasma N-terminal pro-brain natriuretic peptide level in a population-based cohort of nonagenarians.

scientific article published in May 2009

Clinically diagnosed infections predict disability in activities of daily living among the oldest-old in the general population: the Leiden 85-plus Study

scientific article published on 12 March 2013

Co-occurrence of depression and anxiety in elderly subjects aged 90 years and its relationship with functional status, quality of life and mortality

scientific article published in June 2009

Cochrane corner: is integrated disease management for patients with COPD effective?

scientific article

Common chronic diseases and general impairments as determinants of walking disability in the oldest-old population

scientific article published on 01 August 2002

Comparison of quadriceps strength and handgrip strength in their association with health outcomes in older adults in primary care

scientific article

Consequences of interaction of functional, somatic, mental and social problems in community-dwelling older people.

scientific article published on 21 April 2015

Coping strategies of older people with low mood

scientific article published on 9 November 2016

Correction: Predictive Value of a Profile of Routine Blood Measurements on Mortality in Older Persons in the General Population: The Leiden 85-Plus Study

scientific article published on 9 June 2015

Cost-effectiveness of cranberry capsules to prevent urinary tract infection in long-term care facilities: economic evaluation with a randomized controlled trial

scientific article

Cost-effectiveness of integrated COPD care: the RECODE cluster randomised trial

scientific article

Cost-effectiveness research in elderly residents in long-term care: prevention is better than cure, but not always cheaper

scientific article published on January 2015

Cost-utility and cost-effectiveness analysis of a clinical medication review focused on personal goals in older persons with polypharmacy compared to usual care; economic evaluation of the DREAMeR study

scientific article published on 10 June 2020

Cryotherapy with liquid nitrogen versus topical salicylic acid application for cutaneous warts in primary care: randomized controlled trial

scientific article

Current choices in the treatment of cutaneous warts: a survey among Dutch GP.

scientific article published on 7 July 2010

Cutaneous wart-associated HPV types: prevalence and relation with patient characteristics.

scientific article published on 11 August 2012

Cytomegalovirus infection and responsiveness to influenza vaccination in elderly residents of long-term care facilities.

scientific article published on 15 April 2011

DREAMeR: Drug use Reconsidered in the Elderly using goal Attainment scales during Medication Review; study protocol of a randomised controlled trial

scientific article published on 24 August 2018

Determinants of absence of osteoarthritis in old age ⬇️

scientific article published on 05 October 2010

Diagnostic accuracy of plasma NT-proBNP levels for excluding cardiac abnormalities in the very elderly

scientific article

Disability transitions in the oldest old in the general population. The Leiden 85-plus study

scientific article published on 30 August 2013

Does depression in old age increase only cardiovascular mortality? The Leiden 85-plus Study

scientific article published in September 2004

Does depression specifically increase cardiovascular mortality?

scientific article published on 01 January 2005

Drug prescription rates in secondary cardiovascular prevention in old age: Do vulnerability and severity of the history of cardiovascular disease matter?

scientific article published on December 2015

Education within the Dutch National Care for the Elderly Programme

scientific article published on 14 November 2016

Effect of Discontinuation of Antihypertensive Treatment in Elderly People on Cognitive Functioning--the DANTE Study Leiden: A Randomized Clinical Trial

scientific article published on 24 August 2015

Effect of Thyroid Hormone Therapy on Fatigability in Older Adults With Subclinical Hypothyroidism: A Nested Study Within a Randomized Placebo-Controlled Trial

scientific article published on 06 June 2020

Effect of anemia and comorbidity on functional status and mortality in old age: results from the Leiden 85-plus Study.

scientific article published on 27 July 2009

Effect of erythropoietin levels on mortality in old age: the Leiden 85-plus Study

scientific article

Effectiveness and cost-effectiveness of a proactive, goal-oriented, integrated care model in general practice for older people. A cluster randomised controlled trial: Integrated Systematic Care for older People--the ISCOPE study.

scientific article

Effectiveness of cranberry capsules to prevent urinary tract infections in vulnerable older persons: a double-blind randomized placebo-controlled trial in long-term care facilities

scientific article

Effectiveness of integrated disease management for primary care chronic obstructive pulmonary disease patients: results of cluster randomised trial

scientific article

Effectiveness of intramuscular gluteal glucocorticoid injection versus intra-articular glucocorticoid injection in knee osteoarthritis: design of a multicenter randomized, 24 weeks comparative parallel-group trial

scientific article published on 11 April 2020

Effects of a clinical medication review focused on personal goals, quality of life, and health problems in older persons with polypharmacy: A randomised controlled trial (DREAMeR-study)

article

Effects of a stepped-care intervention programme among older subjects who screened positive for depressive symptoms in general practice: the PROMODE randomised controlled trial

scientific article published on 16 March 2012

Effects of medication review on drug-related problems in patients using automated drug-dispensing systems: a pragmatic randomized controlled study

scientific article published on April 2011

Evaluation of a novel broad-spectrum PCR-multiplex genotyping assay for identification of cutaneous wart-associated human papillomavirus types.

scientific article

Evaluation of continuous summary physical performance scores (CSPPS) in an elderly cohort

scientific article published on 01 June 2005

Exploring the variation in implementation of a COPD disease management programme and its impact on health outcomes: a post hoc analysis of the RECODE cluster randomised trial.

scientific article

Feasibility and acceptability of the 'Acutely Presenting Older Patient' screener in routine emergency department care

scientific article published on 18 May 2020

Framingham stroke risk score and cognitive impairment for predicting first-time stroke in the oldest old.

scientific article published on 16 May 2013

GPs' perspectives on preventive care for older people: a focus group study.

scientific article

GPs' perspectives on secondary cardiovascular prevention in older age: a focus group study in the Netherlands

scientific article

Gene dose of apolipoprotein E and age-related hearing loss

scientific article published on 28 April 2012

General practitioners' deprescribing decisions in older adults with polypharmacy: a case vignette study in 31 countries

scientific article published on 07 January 2021

Geriatric Screening, Triage Urgency, and 30-Day Mortality in Older Emergency Department Patients

scientific article published on 04 April 2020

HPV type in plantar warts influences natural course and treatment response: secondary analysis of a randomised controlled trial

scientific article published on 19 March 2013

Handgrip strength and mortality in the oldest old population: the Leiden 85-plus study

scientific article

Handgrip strength as a predictor of functional, psychological and social health. A prospective population-based study among the oldest old.

scientific article

High Sensitivity Cardiac Troponin T and Cognitive Function in the Oldest Old: The Leiden 85-Plus Study

scientific article published on 16 August 2017

High blood pressure and resilience to physical and cognitive decline in the oldest old: the Leiden 85-plus Study

scientific article published on 5 November 2012

High blood pressure, physical and cognitive function, and risk of stroke in the oldest old: the Leiden 85-plus Study

scientific article published on 6 November 2012

High innate production capacity of tumor necrosis factor-alpha and decline of handgrip strength in old age

scientific article published on 07 July 2007

High-density vs low-density lipoprotein cholesterol as the risk factor for coronary artery disease and stroke in old age.

scientific article

Homocysteine levels and treatment effect in the PROspective Study of Pravastatin in the Elderly at Risk

scientific article

Homocysteine, vitamin B-12, and folic acid and the risk of cognitive decline in old age: the Leiden 85-Plus study

scientific article published in October 2005

How do general practitioners identify inflammatory arthritis? A cohort analysis of Dutch general practitioner electronic medical records

scientific article published on 7 January 2016

How general practitioners would deprescribe in frail oldest-old with polypharmacy - the LESS study

scientific article

How usual is usual care in pragmatic intervention studies in primary care? An overview of recent trials.

scientific article

Impact of Thyroid Hormone Therapy on Atherosclerosis in the Elderly With Subclinical Hypothyroidism: A Randomized Trial

scientific article published on 01 August 2018

Impact of mild cognitive impairment on survival in very elderly people: cohort study ⬇️

scientific article published on October 25, 1997

Impact of valvular heart disease on activities of daily living of nonagenarians: the Leiden 85-plus study a population based study

scientific article

Impaired innate immunity predicts frailty in old age. The Leiden 85-plus study

scientific article published on 01 September 2004

In a population-based prospective study, no association between high blood pressure and mortality after age 85 years

scientific article published on 01 February 2006

In an observational study elderly patients had an increased risk of falling due to home hazards

scientific article published in January 2005

Increase in N-terminal pro-brain natriuretic peptide levels, renal function and cardiac disease in the oldest old.

scientific article

Inflammation and interleukin-1 signaling network contribute to depressive symptoms but not cognitive decline in old age.

scientific article published on 4 February 2007

Inflammation underlying cardiovascular mortality is a late consequence of evolutionary programming

scientific article

Integrated disease management interventions for patients with chronic obstructive pulmonary disease

scientific article

Integrated disease management interventions for patients with chronic obstructive pulmonary disease

scientific article (published 2011-11-09)

International variation in GP treatment strategies for subclinical hypothyroidism in older adults: a case-based survey ⬇️

scientific article

Is depression in old age fatal only when people feel lonely?

scientific article

Is education a demographic dividend? The role of cognitive reserve in dementia-related cognitive decline: a comparison of six longitudinal studies of ageing

scientific article published in The Lancet

L-Thyroxine Therapy for Older Adults With Subclinical Hypothyroidism and Hypothyroid Symptoms: Secondary Analysis of a Randomized Trial

scientific article published on 05 May 2020

Late-onset dementia: structural brain damage and total cerebral blood flow

scientific article published on 12 July 2005

Latent class analysis of the Apathy Scale does not identify subtypes of apathy in general population-based older persons

scientific article published on 25 January 2016

Leisure Activities and the Risk of Dementia ⬇️

scientific article published on September 25, 2003

Lesional HPV types of cutaneous warts can be reliably identified by surface swabs ⬇️

scientific article published on July 27, 2011

Level of satisfaction of older persons with their general practitioner and practice: role of complexity of health problems.

scientific article

Low blood pressure predicts increased mortality in very old age even without heart failure: the Leiden 85-plus Study.

scientific article published on 17 December 2012

Low production capacity of interleukin-10 associates with the metabolic syndrome and type 2 diabetes : the Leiden 85-Plus Study

scientific article published in April 2002

Low thyroid function and anemia in old age: the Leiden 85-plus study

scientific article published on 01 February 2015

Low thyroid function is not associated with an accelerated deterioration in renal function.

scientific article published on 18 April 2018

Lower Performance in Orientation to Time and Place Associates with Greater Risk of Cardiovascular Events and Mortality in the Oldest Old: Leiden 85-Plus Study

scientific article published on 27 September 2017

Lower blood pressure during antihypertensive treatment is associated with higher all-cause mortality and accelerated cognitive decline in the oldest-old. Data from the Leiden 85-plus Study

scientific article published on 01 July 2018

Majority of drug-related problems identified during medication review are not associated with STOPP/START criteria.

scientific article

Managing hypertension in frail oldest-old-The role of guideline use by general practitioners from 29 countries

scientific article published on 10 July 2020

Markers of autonomic tone on a standard ECG are predictive of mortality in old age

scientific article published on 01 February 2006

Measuring daily functioning in older persons using a frailty index: a cohort study based on routine primary care data

scientific article published on 02 November 2020

Medication adherence and knowledge of older patients with and without multidose drug dispensing.

scientific article published on 05 July 2013

Medication review in older people: identification of a new risk group

scientific article published in January 2015

Meta-analysis of nonsteroidal antiinflammatory drug use and risk of dementia

scientific article

Meta-analysis: Subclinical Thyroid Dysfunction and the Risk for Coronary Heart Disease and Mortality

scientific article

Monochloroacetic acid application is an effective alternative to cryotherapy for common and plantar warts in primary care: a randomized controlled trial

scientific article published on 05 February 2015

N-terminal pro-brain natriuretic peptide and cognitive decline in older adults at high cardiovascular risk

scientific article published on 9 July 2014

NT-proBNP best predictor of cardiovascular events and cardiovascular mortality in secondary prevention in very old age: the Leiden 85-plus Study

scientific article

NT-proBNP, blood pressure, and cognitive decline in the oldest old: The Leiden 85-plus Study

scientific article

Natural course of care dependency in residents of long-term care facilities: prospective follow-up study

scientific article

Natural course of cutaneous warts among primary schoolchildren: a prospective cohort study

scientific article published on September 2013

Natural history of depression in the oldest old: population-based prospective study

scientific article published in January 2006

No increased mortality risk in older persons with unexplained anaemia

scientific article published on 14 March 2012

Older individuals' views on their personal screening results for complex health problems: a qualitative study

scientific article published on 19 October 2020

Older people coping with low mood: a qualitative study

scientific article published on 17 December 2015

Outcomes of thyroid dysfunction in people aged 80 years and older: an individual patient data meta-analysis of four prospective studies (TULIPS consortium)

scientific article published on 3 October 2020

Patient Characteristics and General Practitioners' Advice to Stop Statins in Oldest-Old Patients: a Survey Study Across 30 Countries

scientific article published on 16 January 2019

Perceived doctor-patient relationship and satisfaction with general practitioner care in older persons in residential homes

scientific article published on 12 April 2018

Phenotypic and functional characterization of CD4 T cells expressing killer Ig-like receptors

scientific article published on 01 December 2004

Physician's Prescribing Preference as an Instrumental Variable: Exploring Assumptions Using Survey Data.

scientific article

Plasma NT-proBNP as predictor of change in functional status, cardiovascular morbidity and mortality in the oldest old: the Leiden 85-plus study

scientific article

Plasma hepcidin levels and anemia in old age. The Leiden 85-Plus Study

scientific article published on 12 October 2012

Potentially inappropriate medication and attitudes of older adults towards deprescribing

scientific article published on 26 October 2020

Predicting Risk of Cognitive Decline in Very Old Adults Using Three Models: The Framingham Stroke Risk Profile; the Cardiovascular Risk Factors, Aging, and Dementia Model; and Oxi-Inflammatory Biomarkers

scientific article published on 14 November 2016

Prediction of functional decline in community-dwelling older persons in general practice: a cohort study.

scientific article published on 11 June 2018

Prediction of mortality and functional decline by changes in eGFR in the very elderly: the Leiden 85-plus study

scientific article

Predictive factors of urinary tract infections among the oldest old in the general population. A population-based prospective follow-up study

scientific article

Predictive value of a profile of routine blood measurements on mortality in older persons in the general population: the Leiden 85-plus Study

scientific article

Predictive value of low ferritin in older persons with anemia with and without inflammation: the Leiden 85-plus Study

scientific article published on 01 August 2010

Prevalence of Carriers of Intermediate and Pathological Polyglutamine Disease-Associated Alleles Among Large Population-Based Cohorts

scientific article published on 01 June 2019

Prevalence of potentially inappropriate prescribing in a subpopulation of older European clinical trial participants: a cross-sectional study.

scientific article

Problems experienced by informal caregivers with older care recipients with and without cognitive impairment

scientific article published on 28 March 2016

Prognostic value of cardiovascular disease status: the Leiden 85-plus study

scientific article published on 04 July 2012

Prospective Study of the Effect of Blood Pressure on Renal Function in Old Age: The Leiden 85-Plus Study

scientific article published on 16 August 2006

Proximity to death is associated with frequency of GP contacts in the oldest old: the Leiden 85-plus study

scientific article published on 04 May 2012

Quality of life and paracetamol in advanced dementia (Q-PID): protocol of a randomised double-blind placebo-controlled crossover trial

scientific article published on 14 November 2018

Quality of life in community-dwelling older persons with apathy

scientific article published on 3 September 2013

RECODE: design and baseline results of a cluster randomized trial on cost-effectiveness of integrated COPD management in primary care

scientific article

Randomised controlled trial of unsolicited occupational therapy in community-dwelling elderly people: the LOTIS trial

scientific article

Recommendations for (Discontinuation of) Statin Treatment in Older Adults: Review of Guidelines

scientific article published on 30 October 2019

Relationship of patient volume and service concentration with outcome in geriatric rehabilitation.

scientific article

Repeat length variations in ATXN1 and AR modify disease expression in Alzheimer's disease

scientific article published on 15 September 2018

Response to David Nace and Paul Drinka

Response to an unsolicited intervention offer to persons aged ≥ 75 years after screening positive for depressive symptoms: a qualitative study.

scientific article published on 16 August 2011

Resting heart rate and incident heart failure and cardiovascular mortality in older adults: role of inflammation and endothelial dysfunction: the PROSPER study

scientific article published on 18 December 2012

Risk stratification and treatment effect of statins in secondary cardiovascular prevention in old age: Additive value of N-terminal pro-B-type natriuretic peptide

scientific article published on 24 November 2015

Satisfaction in Older Persons and General Practitioners during the Implementation of Integrated Care.

scientific article

Seasonal mood variation in the elderly: the Leiden 85-plus study

scientific article published in March 2005

Self-Reported Hindering Health Complaints of Community-Dwelling Older Persons: A Cross-Sectional Study

scientific article

Sensory impairment and cognitive functioning in oldest-old subjects: the Leiden 85+ Study

scientific article published in September 2005

Should subclinical hypothyroidism in older persons be treated?

scientific article published on 01 January 2012

Skeletal Effects of Levothyroxine for Subclinical Hypothyroidism in Older Adults: A TRUST Randomized Trial Nested Study

scientific article published on 01 January 2020

Statin Use and Self-Reported Hindering Muscle Complaints in Older Persons: A Population Based Study

scientific article

Statins and blood pressure

scientific article published in November 2008

Study protocol; Thyroid hormone Replacement for Untreated older adults with Subclinical hypothyroidism - a randomised placebo controlled Trial (TRUST).

scientific article

Subclinical Hypothyroidism and the Risk of Stroke Events and Fatal Stroke: An Individual Participant Data Analysis

scientific article

Subclinical Thyroid Dysfunction and the Risk of Cognitive Decline: a Meta-Analysis of Prospective Cohort Studies.

scientific article

Subclinical Thyroid Dysfunction and the Risk of Heart Failure in Older Persons at High Cardiovascular Risk

scholarly article by David Nanchen et al published March 2012 in The Journal of Clinical Endocrinology and Metabolism

Subclinical hyperthyroidism and the risk of coronary heart disease and mortality.

scientific article published on May 2012

Subclinical hypothyroidism and the risk of coronary heart disease and mortality

scientific article published on September 2010

Subclinical thyroid disorders

Subclinical thyroid dysfunction and cognitive decline in old age

scientific article

Subclinical thyroid dysfunction and depressive symptoms: protocol for a systematic review and individual participant data meta-analysis of prospective cohort studies

scientific article published on 26 July 2019

Subclinical thyroid dysfunction and fracture risk: a meta-analysis

scientific article

Subclinical thyroid dysfunction and functional capacity among elderly.

scientific article

Subclinical thyroid dysfunction and the risk of heart failure events: an individual participant data analysis from 6 prospective cohorts

scientific article

Subnormal vitamin B12 concentrations and anaemia in older people: a systematic review

scientific article

Successful Geriatric Rehabilitation: Effects on Patients' Outcome of a National Program to Improve Quality of Care, the SINGER Study

scientific article published on 6 December 2016

Systolic Blood Pressure and Cognitive Decline in Older Adults With Hypertension

scientific article published on 01 March 2019

THE BIDIRECTIONAL RELATIONSHIP BETWEEN VISION AND COGNITION: A SYSTEMATIC REVIEW AND META-ANALYSIS

scientific article published on 14 December 2020

Telomere length and anaemia in old age: results from the Newcastle 85-plus Study and the Leiden 85-plus Study.

scientific article

Telomere length in white blood cells is not associated with morbidity or mortality in the oldest old: a population-based study.

scientific article

Temporal Relationship Between Cognitive and Physical Performance in Middle-Aged to Oldest Old People

scientific article published on 31 July 2016

Temporal relation between depression and cognitive impairment in old age: prospective population based study

scientific article published on 02 September 2004

The 15-item Geriatric Depression Scale (GDS-15) detects changes in depressive symptoms after a major negative life event. The Leiden 85-plus Study

scientific article published in January 2004

The Dilemma of Treating Subclinical Hypothyroidism: Risk that Current Guidelines Do More Harm than Good.

scientific article

The Effect of Age on the Association Between Blood Pressure and Cognitive Function Later in Life

The Impact of Levothyroxine on Cardiac Function in Older Adults with Mild Subclinical Hypothyroidism: a Randomized Clinical Trial

scientific article published on 11 March 2020

The Relation Between Thyroid Function and Anemia: A Pooled Analysis of Individual Participant Data

article

The accuracy of plasma natriuretic peptide levels for diagnosis of cardiac dysfunction and chronic heart failure in community-dwelling elderly: a systematic review.

scientific article published on 27 August 2009

The additional value of routine electrocardiograms in cardiovascular risk management of older people

scientific article

The association of thyroid function and the risk of kidney function decline: a population-based cohort study

scientific article

The clinically meaningful change in physical performance scores in an elderly cohort.

scientific article published in December 2007

The effect of cognitive impairment on the predictive value of multimorbidity for the increase in disability in the oldest old: the Leiden 85-plus Study

scientific article

The effect of vitamin B12 and folic acid supplementation on routine haematological parameters in older people: an individual participant data meta-analysis

scientific article published on 08 March 2018

The effectiveness of functional task exercise and physical therapy as prevention of functional decline in community dwelling older people with complex health problems

scientific article published on 17 July 2018

The guideline 'Cardiovascular risk management' is too simplified for elderly care

scientific article published on January 1, 2012

The influence of the administration method on scores of the 15-item Geriatric Depression Scale in old age.

scientific article published on 20 February 2012

The relationship between the extent of collaboration of general practitioners and pharmacists and the implementation of recommendations arising from medication review: a systematic review.

scientific article published on February 2013

The routine electrocardiogram for cardiovascular risk stratification in old age: the Leiden 85-plus study.

scientific article published in June 2007

The use of goal attainment scaling during clinical medication review in older persons with polypharmacy

scientific article published on 07 November 2018

Thyroid Function Tests in the Reference Range and Fracture: Individual Participant Analysis of Prospective Cohorts.

scientific article published on 5 May 2017

Thyroid Function Within the Normal Range, Subclinical Hypothyroidism, and the Risk of Atrial Fibrillation

scientific article published on 23 October 2017

Thyroid Function Within the Reference Range and the Risk of Stroke: An Individual Participant Data Analysis

scientific article

Thyroid Function and Risk of Anemia: A Multivariable-Adjusted and Mendelian Randomization Analysis in the UK Biobank

scientific article published on 01 January 2022

Thyroid Hormone Therapy for Older Adults with Subclinical Hypothyroidism.

scientific article published on 3 April 2017

Thyroid antibody status, subclinical hypothyroidism, and the risk of coronary heart disease: an individual participant data analysis

scientific article

Thyroid function within the normal range and risk of coronary heart disease: an individual participant data analysis of 14 cohorts

scientific article

Thyroid status and mortality in nonagenarians from long-lived families and the general population

scientific article published on 25 October 2017

Thyroid status and renal function in older persons in the general population

scientific article published on 15 April 2014

Thyroid status, disability and cognitive function, and survival in old age.

scientific article published in December 2004

Time trends in preventive drug treatment after myocardial infarction in older patients

scientific article

Total joint replacement in the past does not relate to a deteriorated functional level and health status in the oldest old.

scientific article published on 8 May 2012

Unravelling complex primary care programmes to maintain independent living in older people: a systematic overview.

scientific article published on 28 December 2017

Use of Framingham risk score and new biomarkers to predict cardiovascular mortality in older people: population based observational cohort study.

scientific article published on 08 January 2009

Validity of the three apathy items of the Geriatric Depression Scale (GDS-3A) in measuring apathy in older persons

scientific article

Variability in vulnerability assessment of older people by individual general practitioners: a cross-sectional study.

scientific article

Variation in GP decisions on antihypertensive treatment in oldest-old and frail individuals across 29 countries

scientific article

Variation in treatment strategies of Swiss general practitioners for subclinical hypothyroidism in older adults

scientific article published on 28 July 2015

Vitamin B12 and folate and the risk of anemia in old age: the Leiden 85-Plus Study.

scientific article

Walking and Talking as Predictors of Falls in the General Population: The Leiden 85‐Plus Study ⬇️

scientific article published on 01 October 2003

Warts transmitted in families and schools: a prospective cohort.

scientific article published on 22 April 2013

What do older adults with multimorbidity and polypharmacy think about deprescribing? The LESS study - a primary care-based survey

scientific article published on 31 October 2020

Wishes and needs of community-dwelling older persons concerning general practice: A qualitative study.

scientific article

Yield and costs of direct and stepped screening for depressive symptoms in subjects aged 75 years and over in general practice

scientific article published in March 2011

[A treatment plan as method and compass].

scientific article published in January 2015

[Disciplinary proceedings on screening and preventive diagnostics]

scientific article published on 01 January 2009

[The complexity of medical care of frail older patients]

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