List of works - Robert Ehehalt

Acyl-CoA synthetases: fatty acid uptake and metabolic channeling

scientific article

Alterations of phospholipid concentration and species composition of the intestinal mucus barrier in ulcerative colitis: a clue to pathogenesis

article

Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts

scientific article

Anti-inflammatory effects of phosphatidylcholine

scientific article published on 18 July 2007

Aquaporin-8 expression is reduced in ileum and induced in colon of patients with ulcerative colitis.

scientific article

Biliary phosphatidylcholine and lysophosphatidylcholine profiles in sclerosing cholangitis.

scientific article

CYP3A activity in severe liver cirrhosis correlates with Child-Pugh and model for end-stage liver disease (MELD) scores

scientific article published on January 2014

Cellular uptake of fatty acids driven by the ER-localized acyl-CoA synthetase FATP4

scientific article

Cholesterol, lipid rafts, and disease

scientific article

Copper-induced translocation of the Wilson disease protein ATP7B independent of Murr1/COMMD1 and Rab7.

scientific article

Delayed release phosphatidylcholine as new therapeutic drug for ulcerative colitis--a review of three clinical trials.

scientific article published on December 2010

Delayed release phosphatidylcholine in chronic-active ulcerative colitis: a randomized, double-blinded, dose finding study

scientific article published on 01 May 2010

Differential effect of Rhizoma coptidis and its main alkaloid compound berberine on TNF-alpha induced NFkappaB translocation in human keratinocytes

scientific article published on 14 July 2006

Differentially localized acyl-CoA synthetase 4 isoenzymes mediate the metabolic channeling of fatty acids towards phosphatidylinositol

scientific article

Evidence of luminal phosphatidylcholine secretion in rat ileum.

scientific article

FAT/CD36-mediated long-chain fatty acid uptake in adipocytes requires plasma membrane rafts

scientific article

FATP4 contributes as an enzyme to the basal and insulin-mediated fatty acid uptake of C₂C₁₂ muscle cells.

scientific article published on 12 July 2011

Fatty acid- and cholesterol transporter protein expression along the human intestinal tract

scientific article

Flotillin-2 expression in the human gut: from a cell model to human tissue in health and inflammatory bowel diseases

scientific article

Health-related quality of life correlates with clinical and endoscopic activity indexes but not with demographic features in patients with ulcerative colitis

scientific article published in November 2006

Hepcidin is an antibacterial, stress-inducible peptide of the biliary system

scientific article

Identification, sequencing, and cellular localization of hepcidin in guinea pig (Cavia porcellus).

scientific article

Increased basolateral sorting of carcinoembryonic antigen in a polarized colon carcinoma cell line after cholesterol depletion-Implications for treatment of inflammatory bowel disease

scientific article

Interdisciplinary Aspects of Chronic Inflammatory Bowel Diseases

scientific article published on 29 October 2019

Intestinal cytomegalovirus infection in patients hospitalized for exacerbation of inflammatory bowel disease: a 10-year tertiary referral center experience

scientific article published on June 2015

Knockdown of caveolin-1 decreases activity of breast cancer resistance protein (BCRP/ABCG2) and increases chemotherapeutic sensitivity

scientific article published on 10 October 2010

Lipid based therapy for ulcerative colitis-modulation of intestinal mucus membrane phospholipids as a tool to influence inflammation.

scientific article

Lipid droplets lighting up: insights from live microscopy

scientific article published on 30 March 2010

Lipids as modulators of proteolytic activity of BACE: involvement of cholesterol, glycosphingolipids, and anionic phospholipids in vitro

scientific article published on 22 August 2005

Localization of the human breast cancer resistance protein (BCRP/ABCG2) in lipid rafts/caveolae and modulation of its activity by cholesterol in vitro

scientific article

Long-chain fatty acid uptake into adipocytes depends on lipid raft function

scientific article published on April 2004

Loss of EpCAM expression in breast cancer derived serum exosomes: role of proteolytic cleavage

scientific article published on 20 May 2011

Morphologic patterns of autoimmune pancreatitis in CT and MRI.

scientific article published on 27 May 2011

Mucosal protection by phosphatidylcholine.

scientific article published on January 2012

New concepts of cellular fatty acid uptake: role of fatty acid transport proteins and of caveolae.

scientific article published in May 2004

Outlook: membrane junctions enable the metabolic trapping of fatty acids by intracellular acyl-CoA synthetases ⬇️

scientific article published on October 10, 2012

Overexpressed FATP1, ACSVL4/FATP4 and ACSL1 Increase the Cellular Fatty Acid Uptake of 3T3-L1 Adipocytes but Are Localized on Intracellular Membranes ⬇️

scientific article published on September 14, 2012

Overexpression of CD36 and acyl-CoA synthetases FATP2, FATP4 and ACSL1 increases fatty acid uptake in human hepatoma cells

scientific article

Perceived distress, personality characteristics, coping strategies and psychosocial impairments in a national German multicenter cohort of patients with Crohn's disease and ulcerative colitis

scientific article published on 09 April 2019

Phosphatidylcholine (lecithin) and the mucus layer: Evidence of therapeutic efficacy in ulcerative colitis?

scientific article published on 30 September 2010

Phosphatidylcholine as a constituent in the colonic mucosal barrier--physiological and clinical relevance

scientific article published on 04 June 2010

Phosphatidylcholine for steroid-refractory chronic ulcerative colitis: a randomized trial

scientific article published on 01 November 2007

Protein mediated fatty acid uptake: synergy between CD36/FAT-facilitated transport and acyl-CoA synthetase-driven metabolism

scientific article published on 04 February 2014

Real-life outcome of anti-tumor necrosis factor α in the ambulatory treatment of ulcerative colitis.

scientific article

Reduced hydrophobicity of the colonic mucosal surface in ulcerative colitis as a hint at a physicochemical barrier defect ⬇️

scientific article published on April 1, 2011

Regulation of hepcidin in HepG2 and RINm5F cells

scientific article published on 2 February 2007

Results of the 2nd scientific workshop of the ECCO (III): basic mechanisms of intestinal healing.

scientific article published on 11 December 2011

Rhizoma Coptidis inhibits LPS-induced MCP-1/CCL2 production in murine macrophages via an AP-1 and NFkappaB-dependent pathway

scientific article published on 21 June 2010

Risk of Confusion: Detection of a Circular Thickness of the Wall in the Lower Part of the Esophagus

scientific article published on 20 July 2011

Separate basolateral and apical phosphatidylcholine secretion routes in intestinally differentiated tumor cells.

scientific article

Splice variants of the beta-site APP-cleaving enzyme BACE1 in human brain and pancreas

scientific article

Stable isotope and high precision concentration measurements confirm that all humans produce and exhale methane

scientific article published on 29 January 2016

Sustained Clinical Remission With Vedolizumab in Patients With Moderate-to-Severe Ulcerative Colitis

scientific article published on 01 May 2019

TNF-alpha-induced up-regulation of pro-inflammatory cytokines is reduced by phosphatidylcholine in intestinal epithelial cells.

scientific article

The N-terminal region of acyl-CoA synthetase 3 is essential for both the localization on lipid droplets and the function in fatty acid uptake

scientific article

The metabolic capacity of lipid droplet localized acyl-CoA synthetase 3 is not sufficient to support local triglyceride synthesis independent of the endoplasmic reticulum in A431 cells

scientific article published on 09 March 2018

Transcript levels of different cytokines and chemokines correlate with clinical and endoscopic activity in ulcerative colitis

scientific article

Translocation of long chain fatty acids across the plasma membrane--lipid rafts and fatty acid transport proteins.

scientific article

Uptake of long chain fatty acids is regulated by dynamic interaction of FAT/CD36 with cholesterol/sphingolipid enriched microdomains (lipid rafts)

scientific article

List of works by Robert Ehehalt

Acyl-CoA synthetases: fatty acid uptake and metabolic channeling

Alterations of phospholipid concentration and species composition of the intestinal mucus barrier in ulcerative colitis: a clue to pathogenesis

Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts

Anti-inflammatory effects of phosphatidylcholine

Aquaporin-8 expression is reduced in ileum and induced in colon of patients with ulcerative colitis.

Biliary phosphatidylcholine and lysophosphatidylcholine profiles in sclerosing cholangitis.

CYP3A activity in severe liver cirrhosis correlates with Child-Pugh and model for end-stage liver disease (MELD) scores

Cellular uptake of fatty acids driven by the ER-localized acyl-CoA synthetase FATP4

Cholesterol, lipid rafts, and disease

Copper-induced translocation of the Wilson disease protein ATP7B independent of Murr1/COMMD1 and Rab7.

Delayed release phosphatidylcholine as new therapeutic drug for ulcerative colitis--a review of three clinical trials.

Delayed release phosphatidylcholine in chronic-active ulcerative colitis: a randomized, double-blinded, dose finding study

Differential effect of Rhizoma coptidis and its main alkaloid compound berberine on TNF-alpha induced NFkappaB translocation in human keratinocytes

Differentially localized acyl-CoA synthetase 4 isoenzymes mediate the metabolic channeling of fatty acids towards phosphatidylinositol

Evidence of luminal phosphatidylcholine secretion in rat ileum.

FAT/CD36-mediated long-chain fatty acid uptake in adipocytes requires plasma membrane rafts

FATP4 contributes as an enzyme to the basal and insulin-mediated fatty acid uptake of C₂C₁₂ muscle cells.

Fatty acid- and cholesterol transporter protein expression along the human intestinal tract

Flotillin-2 expression in the human gut: from a cell model to human tissue in health and inflammatory bowel diseases

Health-related quality of life correlates with clinical and endoscopic activity indexes but not with demographic features in patients with ulcerative colitis

Hepcidin is an antibacterial, stress-inducible peptide of the biliary system

Identification, sequencing, and cellular localization of hepcidin in guinea pig (Cavia porcellus).

Increased basolateral sorting of carcinoembryonic antigen in a polarized colon carcinoma cell line after cholesterol depletion-Implications for treatment of inflammatory bowel disease

Interdisciplinary Aspects of Chronic Inflammatory Bowel Diseases

Intestinal cytomegalovirus infection in patients hospitalized for exacerbation of inflammatory bowel disease: a 10-year tertiary referral center experience

Knockdown of caveolin-1 decreases activity of breast cancer resistance protein (BCRP/ABCG2) and increases chemotherapeutic sensitivity

Lipid based therapy for ulcerative colitis-modulation of intestinal mucus membrane phospholipids as a tool to influence inflammation.

Lipid droplets lighting up: insights from live microscopy

Lipids as modulators of proteolytic activity of BACE: involvement of cholesterol, glycosphingolipids, and anionic phospholipids in vitro

Localization of the human breast cancer resistance protein (BCRP/ABCG2) in lipid rafts/caveolae and modulation of its activity by cholesterol in vitro

Long-chain fatty acid uptake into adipocytes depends on lipid raft function

Loss of EpCAM expression in breast cancer derived serum exosomes: role of proteolytic cleavage

Morphologic patterns of autoimmune pancreatitis in CT and MRI.

Mucosal protection by phosphatidylcholine.

New concepts of cellular fatty acid uptake: role of fatty acid transport proteins and of caveolae.

Outlook: membrane junctions enable the metabolic trapping of fatty acids by intracellular acyl-CoA synthetases ⬇️

Overexpressed FATP1, ACSVL4/FATP4 and ACSL1 Increase the Cellular Fatty Acid Uptake of 3T3-L1 Adipocytes but Are Localized on Intracellular Membranes ⬇️

Overexpression of CD36 and acyl-CoA synthetases FATP2, FATP4 and ACSL1 increases fatty acid uptake in human hepatoma cells

Perceived distress, personality characteristics, coping strategies and psychosocial impairments in a national German multicenter cohort of patients with Crohn's disease and ulcerative colitis

Phosphatidylcholine (lecithin) and the mucus layer: Evidence of therapeutic efficacy in ulcerative colitis?

Phosphatidylcholine as a constituent in the colonic mucosal barrier--physiological and clinical relevance

Phosphatidylcholine for steroid-refractory chronic ulcerative colitis: a randomized trial

Protein mediated fatty acid uptake: synergy between CD36/FAT-facilitated transport and acyl-CoA synthetase-driven metabolism

Real-life outcome of anti-tumor necrosis factor α in the ambulatory treatment of ulcerative colitis.

Reduced hydrophobicity of the colonic mucosal surface in ulcerative colitis as a hint at a physicochemical barrier defect ⬇️

Regulation of hepcidin in HepG2 and RINm5F cells

Results of the 2nd scientific workshop of the ECCO (III): basic mechanisms of intestinal healing.

Rhizoma Coptidis inhibits LPS-induced MCP-1/CCL2 production in murine macrophages via an AP-1 and NFkappaB-dependent pathway

Risk of Confusion: Detection of a Circular Thickness of the Wall in the Lower Part of the Esophagus

Separate basolateral and apical phosphatidylcholine secretion routes in intestinally differentiated tumor cells.

Splice variants of the beta-site APP-cleaving enzyme BACE1 in human brain and pancreas

Stable isotope and high precision concentration measurements confirm that all humans produce and exhale methane

Sustained Clinical Remission With Vedolizumab in Patients With Moderate-to-Severe Ulcerative Colitis

TNF-alpha-induced up-regulation of pro-inflammatory cytokines is reduced by phosphatidylcholine in intestinal epithelial cells.

The N-terminal region of acyl-CoA synthetase 3 is essential for both the localization on lipid droplets and the function in fatty acid uptake

The metabolic capacity of lipid droplet localized acyl-CoA synthetase 3 is not sufficient to support local triglyceride synthesis independent of the endoplasmic reticulum in A431 cells

Transcript levels of different cytokines and chemokines correlate with clinical and endoscopic activity in ulcerative colitis

Translocation of long chain fatty acids across the plasma membrane--lipid rafts and fatty acid transport proteins.

Uptake of long chain fatty acids is regulated by dynamic interaction of FAT/CD36 with cholesterol/sphingolipid enriched microdomains (lipid rafts)