List of works - Volker Gerdts

A Porcine Model of Zika Virus Infection to Profile the In Utero Interferon Alpha Response

scientific article published on 01 January 2020

A comparison between isolated blood dendritic cells and monocyte-derived dendritic cells in pigs

scientific article published on 16 November 2009

A lipidic delivery system of a triple vaccine adjuvant enhances mucosal immunity following nasal administration in mice

scientific article published on 07 February 2019

A lumpy skin disease virus deficient of an IL-10 gene homologue provides protective immunity against virulent capripoxvirus challenge in sheep and goats

scientific article

A novel combination adjuvant platform for human and animal vaccines.

scientific article published on 06 June 2017

A novel vaccine adjuvant comprised of a synthetic innate defence regulator peptide and CpG oligonucleotide links innate and adaptive immunity

scientific article published on 17 June 2009

Adjuvants for veterinary vaccines--types and modes of action

scientific article

Administration of Poly[di(sodium carboxylatoethylphenoxy)phosphazene] (PCEP) and Avian Beta Defensin as Adjuvants in Inactivated Inclusion Body Hepatitis Virus and its Hexon Protein-Based Experimental Vaccine Formulations in Chickens

scientific article published on December 2015

Administration of poly[di(sodium carboxylatoethylphenoxy)]phosphazene (PCEP) as adjuvant activated mixed Th1/Th2 immune responses in pigs

scientific article

All three classes of CpG ODNs up-regulate IP-10 gene in pigs

scientific article published on 5 November 2009

Analysis of immune responses to recombinant proteins from strains of Mycoplasma mycoides subsp. mycoides, the causative agent of contagious bovine pleuropneumonia

scientific article published on 9 September 2015

Animal models for neonatal diseases in humans

scientific article published on 10 December 2012

Antibody and Cytokine Responses of Koalas (Phascolarctos cinereus) Vaccinated with Recombinant Chlamydial Major Outer Membrane Protein (MOMP) with Two Different Adjuvants

scientific article

Antibody response specific to the capsular polysaccharide is impaired in Streptococcus suis serotype 2-infected animals

scientific article

Antibody responses in adult and neonatal BALB/c mice to immunization with novel Bordetella pertussis vaccine formulations

scientific article published on 05 January 2011

Biological roles of host defense peptides: lessons from transgenic animals and bioengineered tissues

scientific article

CD71+ erythroid suppressor cells impair adaptive immunity against Bordetella pertussis.

scientific article published on 10 August 2017

Canadian Adjuvant Initiative Workshop, March 26-27, 2013--Ottawa, Canada

scientific article

Capripoxvirus-vectored vaccines against livestock diseases in Africa.

scientific article published on 07 March 2013

Capsular polysaccharide from Mycoplasma mycoides subsp. mycoides shows potential for protection against contagious bovine pleuropneumonia

scientific article published on 4 July 2016

Carrier molecules for use in veterinary vaccines

scientific article published on 07 December 2012

Caspase-1 Dependent IL-1β Secretion and Antigen-Specific T-Cell Activation by the Novel Adjuvant, PCEP.

scientific article published on 26 June 2014

Combination adjuvants: the next generation of adjuvants?

scientific article published on January 2011

Commensal bacteria and expression of two major intestinal chemokines, TECK/CCL25 and MEC/CCL28, and their receptors

scientific article

Contribution of the swine model in the study of human sexually transmitted infections

scientific article published on 23 November 2017

Corrigendum to "Zika Virus Causes Persistent Infection in Porcine Conceptuses and May Impair Health in Offspring".

scientific article published on 21 October 2017

CpG oligodeoxynucleotides activate innate immune response that suppresses infectious bronchitis virus replication in chicken embryos

scientific article

CpG-ODNs induced changes in cytokine/chemokines genes expression associated with suppression of infectious bronchitis virus replication in chicken lungs

scientific article published on 21 May 2014

CpG-Recoding in Zika Virus Genome Causes Host-Age-Dependent Attenuation of Infection With Protection Against Lethal Heterologous Challenge in Mice

scholarly article by Ivan Trus et al published 2019 in Frontiers in Immunology

DNA vaccination in utero: a new approach to induce protective immunity in the newborn

scientific article published on April 2004

Differential activation and maturation of two porcine DC populations following TLR ligand stimulation

scientific article published on 11 May 2010

Does adjuvanticity depend on the ability to recruit specific immune cells?

scientific article published in April 2011

Early immune response following Salmonella enterica subspecies enterica serovar Typhimurium infection in porcine jejunal gut loops

scientific article published on 16 October 2008

Enzymatic modification of lipid A by ArnT protects Bordetella bronchiseptica against cationic peptides and is required for transmission.

scientific article published on 14 October 2013

Experimental evaluation of inactivated and live attenuated vaccines against Mycoplasma mycoides subsp. mycoides

scientific article published on 17 December 2015

Expression of TECK/CCL25 and MEC/CCL28 chemokines and their respective receptors CCR9 and CCR10 in porcine mucosal tissues.

scientific article

Expression of mucosal chemokines TECK/CCL25 and MEC/CCL28 during fetal development of the ovine mucosal immune system.

scientific article published on 22 January 2007

Failure of a VapA/CpG oligodeoxynucleotide vaccine to protect foals against experimental Rhocococcus equi pneumonia despite induction of VapA-specific antibody and interferon-γ response

scientific article published on July 2013

Future vaccines for a globalized world

scientific article published on July 2012

High dosage of zinc modulates T-cells in a time-dependent manner within porcine gut-associated lymphatic tissue

scientific article published on 02 November 2018

Humoral and cellular factors of maternal immunity in swine.

scientific article published on 28 August 2008

Immune responses to in ovo vaccine formulations containing inactivated fowl adenovirus 8b with poly[di(sodium carboxylatoethylphenoxy)]phosphazene (PCEP) and avian beta defensin as adjuvants in chickens

scientific article published on 10 January 2017

Immunization of a wild koala population with a recombinant Chlamydia pecorum Major Outer Membrane Protein (MOMP) or Polymorphic Membrane Protein (PMP) based vaccine: New insights into immune response, protection and clearance

scientific article

Immunization with PCEP microparticles containing pertussis toxoid, CpG ODN and a synthetic innate defense regulator peptide induces protective immunity against pertussis

scientific article published on 21 July 2011

In Ovo Administration of Innate Immune Stimulants and Protection from Early Chick Mortalities due to Yolk Sac Infection

scientific article published on 01 September 2018

Induction, regulation and physiological role of IL-17 secreting helper T-cells isolated from PBMC, thymus, and lung lymphocytes of young pigs

scientific article published on 10 September 2011

Infection with Bordetella parapertussis but not Bordetella pertussis causes pertussis-like disease in older pigs

scientific article

Influence of maternal antibodies on active pertussis toxoid immunization of neonatal mice and piglets

scientific article published on 19 August 2011

Innate immunemodulator containing adjuvant formulated HA based vaccine protects mice from lethal infection of highly pathogenic avian influenza H5N1 virus

scientific article published on 31 January 2020

Intradermal immunization with inactivated swine influenza virus and adjuvant polydi(sodium carboxylatoethylphenoxy)phosphazene (PCEP) induced humoral and cell-mediated immunity and reduced lung viral titres in pigs

scientific article published on 14 February 2018

Intranasal vaccination with an adjuvanted polyphosphazenes nanoparticle-based vaccine formulation stimulates protective immune responses in mice

scientific article published on June 2017

Large animal models for vaccine development and testing.

scientific article published on January 2015

Maternal immunity provides protection against pertussis in newborn piglets

scientific article

Molecular cloning and functional characterization of porcine CCL28: possible involvement in homing of IgA antibody secreting cells into the mammary gland.

scientific article published on 11 June 2007

Mouse and pig models for studies of natural and vaccine-induced immunity to Bordetella pertussis.

scientific article published on April 2014

Mucosal delivery of vaccines in domestic animals

scientific article

Multistage vaccines containing outer membrane, type III secretion system and inclusion membrane proteins protects against a Chlamydia genital tract infection and pathology

scientific article published on 08 June 2017

Neonatal pigs are susceptible to experimental Zika virus infection

scientific article published on 15 February 2017

New insights into the dual recruitment of IgA+ B cells in the developing mammary gland.

scientific article published on 3 June 2008

Novel vaccine formulations against pertussis offer earlier onset of immunity and provide protection in the presence of maternal antibodies

scientific article published on 15 May 2013

Oral DNA vaccination in utero induces mucosal immunity and immune memory in the neonate

scientific article published on February 2002

Oral antigen exposure in newborn piglets circumvents induction of oral tolerance in response to intraperitoneal vaccination in later life.

scientific article

PCEP enhances IgA mucosal immune responses in mice following different immunization routes with influenza virus antigens ⬇️

scientific article published on August 24, 2010

PCPP (poly[di(carboxylatophenoxy)-phosphazene]) microparticles co-encapsulating ovalbumin and CpG oligo-deoxynucleotides are potent enhancers of antigen specific Th1 immune responses in mice

scientific article published on 29 October 2010

Pathotypic and molecular characterization of a fowl adenovirus associated with inclusion body hepatitis in Saskatchewan chickens

scientific article published in March 2012

Persistent Zika virus infection in porcine conceptuses is associated with elevated in utero cortisol levels

scientific article published on 01 January 2018

Peste des petits ruminants virus tissue tropism and pathogenesis in sheep and goats following experimental infection

scientific article published on 30 January 2014

Porcine neonatal blood dendritic cells, but not monocytes, are more responsive to TLRs stimulation than their adult counterparts

scientific article

Protection of neonates and infants by maternal immunization

scientific article published on June 2016

Protective Role of Passively Transferred Maternal Cytokines against Bordetella pertussis Infection in Newborn Piglets

scientific article published on 6 February 2017

Protein chimeras containing the Mycoplasma bovis GAPDH protein and bovine host-defence peptides retain the properties of the individual components

scientific article published on 3 February 2011

Recombinant Mycoplasma mycoides proteins elicit protective immune responses against contagious bovine pleuropneumonia

scientific article

Regional Dichotomy in Enteric Mucosal Immune Responses to a Persistent Mycobacterium avium ssp. paratuberculosis Infection

scientific article published on 29 May 2020

S1 domain of the porcine epidemic diarrhea virus spike protein as a vaccine antigen

scientific article published on April 2016

Safety and immunogenicity of a prototype anti-Chlamydia pecorum recombinant protein vaccine in lambs and pregnant ewes.

scientific article published on 18 May 2017

Stability of expression of reference genes in porcine peripheral blood mononuclear and dendritic cells

scientific article published on 13 January 2011

Strategies to Stimulate Innate Immunity for Designing Effective Vaccine Adjuvants

Strategies to link innate and adaptive immunity when designing vaccine adjuvants

scientific article

Subclinical in utero Zika virus infection is associated with interferon alpha sequelae and sex-specific molecular brain pathology in asymptomatic porcine offspring.

scientific article published on 14 November 2019

Susceptibility of Chicken Embryos, Sheep, Cattle, Pigs, and Chickens to Zika Virus Infection

scientific article published on 05 February 2020

Synthetic Cationic Peptide IDR-1002 and Human Cathelicidin LL37 Modulate the Cell Innate Response but Differentially Impact PRRSV Replication in vitro

scientific article published on 12 July 2019

The African strain of Zika virus causes more severe in utero infection than Asian strain in a porcine fetal transmission model

scientific article published on 01 January 2019

The benefits of using diverse animal models for studying pertussis.

scientific article published on 24 October 2007

The host defense peptide beta-defensin 1 confers protection against Bordetella pertussis in newborn piglets

scientific article

The pig: a model for human infectious diseases

scientific article published on 05 December 2011

The potential of polyphosphazenes for delivery of vaccine antigens and immunotherapeutic agents

scientific article published on January 2010

Toll-like receptor 4 variants reduce airway response in human subjects at high endotoxin levels in a swine facility.

scientific article published on 14 April 2009

Use of animal models in the development of human vaccines

scientific article published on December 2007

Vaccination of koalas (Phascolarctos cinereus) against Chlamydia pecorum using synthetic peptides derived from the major outer membrane protein.

scientific article published on 28 June 2018

Vaccination of koalas (Phascolarctos cinereus) with a recombinant chlamydial major outer membrane protein adjuvanted with poly I:C, a host defense peptide and polyphosphazine, elicits strong and long lasting cellular and humoral immune responses.

scientific article published on 04 September 2014

Vaccine Potentiation by Combination Adjuvants ⬇️

scientific article published on 14 April 2014

Vaccines for porcine epidemic diarrhea virus and other swine coronaviruses

scientific article published on 02 December 2016

Veterinary vaccines: alternatives to antibiotics?

scientific article published on December 2008

Zika Virus Causes Persistent Infection in Porcine Conceptuses and may Impair Health in Offspring

scientific article published on 21 September 2017

Zika Virus with Increased CpG Dinucleotide Frequencies Shows Oncolytic Activity in Glioblastoma Stem Cells

scientific article published on 25 May 2020

c-di-GMP enhances protective innate immunity in a murine model of pertussis

scientific article

List of works by Volker Gerdts

A Porcine Model of Zika Virus Infection to Profile the In Utero Interferon Alpha Response

A comparison between isolated blood dendritic cells and monocyte-derived dendritic cells in pigs

A lipidic delivery system of a triple vaccine adjuvant enhances mucosal immunity following nasal administration in mice

A lumpy skin disease virus deficient of an IL-10 gene homologue provides protective immunity against virulent capripoxvirus challenge in sheep and goats

A novel combination adjuvant platform for human and animal vaccines.

A novel vaccine adjuvant comprised of a synthetic innate defence regulator peptide and CpG oligonucleotide links innate and adaptive immunity

Adjuvants for veterinary vaccines--types and modes of action

Administration of Poly[di(sodium carboxylatoethylphenoxy)phosphazene] (PCEP) and Avian Beta Defensin as Adjuvants in Inactivated Inclusion Body Hepatitis Virus and its Hexon Protein-Based Experimental Vaccine Formulations in Chickens

Administration of poly[di(sodium carboxylatoethylphenoxy)]phosphazene (PCEP) as adjuvant activated mixed Th1/Th2 immune responses in pigs

All three classes of CpG ODNs up-regulate IP-10 gene in pigs

Analysis of immune responses to recombinant proteins from strains of Mycoplasma mycoides subsp. mycoides, the causative agent of contagious bovine pleuropneumonia

Animal models for neonatal diseases in humans

Antibody and Cytokine Responses of Koalas (Phascolarctos cinereus) Vaccinated with Recombinant Chlamydial Major Outer Membrane Protein (MOMP) with Two Different Adjuvants

Antibody response specific to the capsular polysaccharide is impaired in Streptococcus suis serotype 2-infected animals

Antibody responses in adult and neonatal BALB/c mice to immunization with novel Bordetella pertussis vaccine formulations

Biological roles of host defense peptides: lessons from transgenic animals and bioengineered tissues

CD71+ erythroid suppressor cells impair adaptive immunity against Bordetella pertussis.

Canadian Adjuvant Initiative Workshop, March 26-27, 2013--Ottawa, Canada

Capripoxvirus-vectored vaccines against livestock diseases in Africa.

Capsular polysaccharide from Mycoplasma mycoides subsp. mycoides shows potential for protection against contagious bovine pleuropneumonia

Carrier molecules for use in veterinary vaccines

Caspase-1 Dependent IL-1β Secretion and Antigen-Specific T-Cell Activation by the Novel Adjuvant, PCEP.

Combination adjuvants: the next generation of adjuvants?

Commensal bacteria and expression of two major intestinal chemokines, TECK/CCL25 and MEC/CCL28, and their receptors

Contribution of the swine model in the study of human sexually transmitted infections

Corrigendum to "Zika Virus Causes Persistent Infection in Porcine Conceptuses and May Impair Health in Offspring".

CpG oligodeoxynucleotides activate innate immune response that suppresses infectious bronchitis virus replication in chicken embryos

CpG-ODNs induced changes in cytokine/chemokines genes expression associated with suppression of infectious bronchitis virus replication in chicken lungs

CpG-Recoding in Zika Virus Genome Causes Host-Age-Dependent Attenuation of Infection With Protection Against Lethal Heterologous Challenge in Mice

DNA vaccination in utero: a new approach to induce protective immunity in the newborn

Differential activation and maturation of two porcine DC populations following TLR ligand stimulation

Does adjuvanticity depend on the ability to recruit specific immune cells?

Early immune response following Salmonella enterica subspecies enterica serovar Typhimurium infection in porcine jejunal gut loops

Enzymatic modification of lipid A by ArnT protects Bordetella bronchiseptica against cationic peptides and is required for transmission.

Experimental evaluation of inactivated and live attenuated vaccines against Mycoplasma mycoides subsp. mycoides

Expression of TECK/CCL25 and MEC/CCL28 chemokines and their respective receptors CCR9 and CCR10 in porcine mucosal tissues.

Expression of mucosal chemokines TECK/CCL25 and MEC/CCL28 during fetal development of the ovine mucosal immune system.

Failure of a VapA/CpG oligodeoxynucleotide vaccine to protect foals against experimental Rhocococcus equi pneumonia despite induction of VapA-specific antibody and interferon-γ response

Future vaccines for a globalized world

High dosage of zinc modulates T-cells in a time-dependent manner within porcine gut-associated lymphatic tissue

Humoral and cellular factors of maternal immunity in swine.

Immune responses to in ovo vaccine formulations containing inactivated fowl adenovirus 8b with poly[di(sodium carboxylatoethylphenoxy)]phosphazene (PCEP) and avian beta defensin as adjuvants in chickens

Immunization of a wild koala population with a recombinant Chlamydia pecorum Major Outer Membrane Protein (MOMP) or Polymorphic Membrane Protein (PMP) based vaccine: New insights into immune response, protection and clearance

Immunization with PCEP microparticles containing pertussis toxoid, CpG ODN and a synthetic innate defense regulator peptide induces protective immunity against pertussis

In Ovo Administration of Innate Immune Stimulants and Protection from Early Chick Mortalities due to Yolk Sac Infection

Induction, regulation and physiological role of IL-17 secreting helper T-cells isolated from PBMC, thymus, and lung lymphocytes of young pigs

Infection with Bordetella parapertussis but not Bordetella pertussis causes pertussis-like disease in older pigs

Influence of maternal antibodies on active pertussis toxoid immunization of neonatal mice and piglets

Innate immunemodulator containing adjuvant formulated HA based vaccine protects mice from lethal infection of highly pathogenic avian influenza H5N1 virus

Intradermal immunization with inactivated swine influenza virus and adjuvant polydi(sodium carboxylatoethylphenoxy)phosphazene (PCEP) induced humoral and cell-mediated immunity and reduced lung viral titres in pigs

Intranasal vaccination with an adjuvanted polyphosphazenes nanoparticle-based vaccine formulation stimulates protective immune responses in mice

Large animal models for vaccine development and testing.

Maternal immunity provides protection against pertussis in newborn piglets

Molecular cloning and functional characterization of porcine CCL28: possible involvement in homing of IgA antibody secreting cells into the mammary gland.

Mouse and pig models for studies of natural and vaccine-induced immunity to Bordetella pertussis.

Mucosal delivery of vaccines in domestic animals

Multistage vaccines containing outer membrane, type III secretion system and inclusion membrane proteins protects against a Chlamydia genital tract infection and pathology

Neonatal pigs are susceptible to experimental Zika virus infection

New insights into the dual recruitment of IgA+ B cells in the developing mammary gland.

Novel vaccine formulations against pertussis offer earlier onset of immunity and provide protection in the presence of maternal antibodies

Oral DNA vaccination in utero induces mucosal immunity and immune memory in the neonate

Oral antigen exposure in newborn piglets circumvents induction of oral tolerance in response to intraperitoneal vaccination in later life.

PCEP enhances IgA mucosal immune responses in mice following different immunization routes with influenza virus antigens ⬇️

PCPP (poly[di(carboxylatophenoxy)-phosphazene]) microparticles co-encapsulating ovalbumin and CpG oligo-deoxynucleotides are potent enhancers of antigen specific Th1 immune responses in mice

Pathotypic and molecular characterization of a fowl adenovirus associated with inclusion body hepatitis in Saskatchewan chickens

Persistent Zika virus infection in porcine conceptuses is associated with elevated in utero cortisol levels

Peste des petits ruminants virus tissue tropism and pathogenesis in sheep and goats following experimental infection

Porcine neonatal blood dendritic cells, but not monocytes, are more responsive to TLRs stimulation than their adult counterparts

Protection of neonates and infants by maternal immunization

Protective Role of Passively Transferred Maternal Cytokines against Bordetella pertussis Infection in Newborn Piglets

Protein chimeras containing the Mycoplasma bovis GAPDH protein and bovine host-defence peptides retain the properties of the individual components

Recombinant Mycoplasma mycoides proteins elicit protective immune responses against contagious bovine pleuropneumonia

Regional Dichotomy in Enteric Mucosal Immune Responses to a Persistent Mycobacterium avium ssp. paratuberculosis Infection

S1 domain of the porcine epidemic diarrhea virus spike protein as a vaccine antigen

Safety and immunogenicity of a prototype anti-Chlamydia pecorum recombinant protein vaccine in lambs and pregnant ewes.

Stability of expression of reference genes in porcine peripheral blood mononuclear and dendritic cells

Strategies to Stimulate Innate Immunity for Designing Effective Vaccine Adjuvants

Strategies to link innate and adaptive immunity when designing vaccine adjuvants

Subclinical in utero Zika virus infection is associated with interferon alpha sequelae and sex-specific molecular brain pathology in asymptomatic porcine offspring.