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List of works by Walter J Schulz-Schaeffer

A First Tetraplex Assay for the Simultaneous Quantification of Total α-Synuclein, Tau, β-Amyloid42 and DJ-1 in Human Cerebrospinal Fluid

scientific article

A human brain vascular atlas reveals diverse mediators of Alzheimer’s risk

scientific article

Accumulation of pathological prion protein PrPSc in the skin of animals with experimental and natural scrapie

scientific article

Acid Sphingomyelinase Deficiency Ameliorates Farber Disease ⬇️

scientific article published on 11 December 2019

Agent strain variation in human prion disease: insights from a molecular and pathological review of the National Institutes of Health series of experimentally transmitted disease

scientific article

Alpha-synuclein is associated with the synaptic vesicle apparatus in the human and rat enteric nervous system

scientific article

Alpha-synuclein seeds of Parkinson´s disease show high prion-exceeding resistance to steam sterilization

scientific article published on 30 October 2020

Analysis of the vasculature by immunohistochemistry in paraffin-embedded brains

scientific article published on 19 December 2017

Antitumor effects of a combined 5-aza-2'deoxycytidine and valproic acid treatment on rhabdomyosarcoma and medulloblastoma in Ptch mutant mice

scientific article published on 20 January 2009

Antitumoral effects of calcitriol in basal cell carcinomas involve inhibition of hedgehog signaling and induction of vitamin D receptor signaling and differentiation

scientific article

Application of an in vitro-amplification assay as a novel pre-screening test for compounds inhibiting the aggregation of prion protein scrapie

scientific article published on 07 July 2016

Assessment of beta-amyloid deposits in human brain: a study of the BrainNet Europe Consortium

scientific article

Asynchronous onset of clinical disease in BSE-infected macaques

scientific article published on July 2013

BSE and variant CJD: about the difficulties to establish a new pathogenetic principle

scientific article published in February 2002

BSE-associated prion-amyloid cardiomyopathy in primates

scientific article

Biological confounders for the values of cerebrospinal fluid proteins in Parkinson's disease and related disorders

scientific article published on 10 October 2015

Bov-tA short interspersed nucleotide element sequences in circulating nucleic acids from sera of cattle with bovine spongiform encephalopathy (BSE) and sera of cattle exposed to BSE.

scientific article published on July 2005

Brain biopsy in patients with suspected Creutzfeldt-Jakob disease

scientific article published in October 2008

Brain-derived proteins in the CSF: do they correlate with brain pathology in CJD?

scientific article

Broad transcriptional dysregulation of brain and choroid plexus cell types with COVID-19 ⬇️

journal article from 'bioRxiv' published in 2020

Burial of the Polymorphic Residue 129 in Amyloid Fibrils of Prion Stop Mutants ⬇️

scientific article published on December 3, 2012

CSF amyloid-β peptides in neuropathologically diagnosed dementia with Lewy bodies and Alzheimer's disease

scientific article published in January 2011

Calcitriol Inhibits Hedgehog Signaling and Induces Vitamin D Receptor Signaling and Differentiation in thePatchedMouse Model of Embryonal Rhabdomyosarcoma ⬇️

scientific article published on February 21, 2012

Camptocormia and myopathy

scientific article published on 01 November 2010

Camptocormia in Parkinson's Disease: A Muscle Disease Due to Dysregulated Proprioceptive Polysynaptic Reflex Arch

scientific article published on 21 June 2016

Camptocormia in idiopathic Parkinson's disease: a focal myopathy of the paravertebral muscles

scientific article published on 01 April 2010

Cathodal transcranial direct current stimulation induces regional, long-lasting reductions of cortical blood flow in rats

scientific article

Cellular prion protein directly interacts with and enhances lactate dehydrogenase expression under hypoxic conditions.

scientific article published on 27 May 2015

Cellular prion protein mediates early apoptotic proteome alternation and phospho-modification in human neuroblastoma cells

scientific article published on 19 January 2017

Cerebellar Amyloid-β Plaques: How Frequent Are They, and Do They Influence 18F-Florbetaben SUV Ratios?

scientific article published on 30 June 2016

Chiropractic treatment of temporomandibular disorders using the activator adjusting instrument: a prospective case series.

scientific article published in September 2003

Chloroquine activates the p53 pathway and induces apoptosis in human glioma cells

scientific article

Cholesterol depletion reduces aggregation of amyloid-beta peptide in hippocampal neurons

scientific article published on 14 June 2006

Circulating endothelial cells as potential diagnostic biomarkers in primary central nervous system vasculitis

scientific article

Classification of sporadic Creutzfeldt-Jakob disease based on molecular and phenotypic analysis of 300 subjects

Clinical Definition of Camptocormia in Parkinson's Disease

scientific article published on 11 October 2016

Clinical and magnetic resonance imaging monitoring in progressive multifocal leukoencephalopathy treated with pembrolizumab: a case report

scientific article published on 22 July 2020

Clinical course in young patients with sporadic Creutzfeldt-Jakob disease

scientific article

Clinical features and diagnosis of the MM2 cortical subtype of sporadic Creutzfeldt-Jakob disease

scientific article published in June 2006

Clinical findings and diagnosis in genetic prion diseases in Germany

scientific article published on 16 June 2015

Clinical findings and diagnostic tests in the MV2 subtype of sporadic CJD.

scientific article published on 23 May 2006

Clinical findings in sporadic Creutzfeldt-Jakob disease correlate with thalamic pathology

scientific article published in November 2002

Codon 129 polymorphism specific cerebrospinal fluid proteome pattern in sporadic Creutzfeldt-Jakob disease and the implication of glycolytic enzymes in prion-induced pathology.

scientific article published on 13 October 2010

Correction to: Unexpected high frequency of neurofibroma in the celiac ganglion of German cattle

scientific article published on 15 October 2020

Current clinical diagnosis in Creutzfeldt-Jakob disease: Identification of uncommon variants

scientific article published on 01 September 2000

DMBA/TPA treatment is necessary for BCC formation from patched deficient epidermal cells in Ptch(flox/flox)CD4Cre(+/-) mice

scientific article published on 24 March 2014

Decontamination of medical devices from pathological amyloid-β-, tau- and α-synuclein aggregates

scientific article published on 25 October 2014

Deletion of cellular prion protein results in reduced Akt activation, enhanced postischemic caspase-3 activation, and exacerbation of ischemic brain injury

scientific article

Depletion of cutaneous macrophages and dendritic cells promotes growth of basal cell carcinoma in mice

scientific article

Detection of Mycobacterium avium ssp. paratuberculosis in ileocaecal lymph nodes collected from elderly slaughter cows using a semi-nested IS900 polymerase chain reaction ⬇️

scientific article published on July 2, 2011

Detergents modify proteinase K resistance of PrPSc in different transmissible spongiform encephalopathies (TSEs) ⬇️

scientific article published on December 14, 2011

Development of electrochemiluminescence-based singleplex and multiplex assays for the quantification of α-synuclein and other proteins in cerebrospinal fluid ⬇️

scientific article published on March 23, 2012

Diagnostic problems during late course in Creutzfeldt-Jakob disease

scientific article published on 01 May 2003

Diagnostic value of periodic complexes in Creutzfeldt-Jakob disease

scientific article published on 01 November 2004

Different CSF β-amyloid processing in Alzheimer’s and Creutzfeldt–Jakob disease

scientific article published on 06 January 2011

Direct quantification of CSF alpha-synuclein by ELISA and first cross-sectional study in patients with neurodegeneration

scientific article

Diversity of Clinically Relevant Outcomes Resulting from Hypofractionated Radiation in Human Glioma Stem Cells Mirrors Distinct Patterns of Transcriptomic Changes

scientific article published on 01 March 2020

Doxycycline in early CJD: a double-blinded randomised phase II and observational study.

scientific article

Dysregulation of brain and choroid plexus cell types in severe COVID-19

scientific article

Effect of neurostimulation on camptocormia in Parkinson's disease depends on symptom duration

scientific article published on 12 February 2015

Erratum to: Different CSF β-amyloid processing in Alzheimer’s and Creutzfeldt–Jakob disease

scholarly article published in Journal of Neural Transmission

Erythropoietin augments survival of glioma cells after radiation and temozolomide

scientific article

Evaluation of efficacy and biocompatibility of a novel semisynthetic collagen matrix as a dural onlay graft in a large animal model ⬇️

scientific article published on July 9, 2011

Fatal familial insomnia: Clinical features and early identification

scientific article published in May 2008

Filtration of protein aggregates increases the accuracy for diagnosing prion diseases in brain biopsies

scientific article published in August 2013

Florbetaben PET imaging to detect amyloid beta plaques in Alzheimer's disease: phase 3 study

scientific article published on 27 March 2015

Fluorescence-guided operation in recurrent glioblastoma multiforme treated with bevacizumab-fluorescence of the noncontrast enhancing tumor tissue?

scientific article published on 9 July 2012

Follow-up investigations of tau protein and S-100B levels in cerebrospinal fluid of patients with Creutzfeldt-Jakob disease.

scientific article

Foodborne transmission of bovine spongiform encephalopathy to nonhuman primates

scientific article

Foodborne-Transmitted Prions From the Brain of Cows With Bovine Spongiform Encephalopathy Ascend in Afferent Neurons to the Simian Central Nervous System and Spread to Tonsils and Spleen at a Late Stage of the Incubation Period

scientific article

Hereditary Human Prion Diseases: an Update

scientific article published on 20 June 2016

Histopathology and Florbetaben PET in Patients Incorrectly Diagnosed with Alzheimer's Disease

scientific article published on 9 December 2016

Human glioma-initiating cells show a distinct immature phenotype resembling but not identical to NG2 glia

scientific article published on April 2013

Immunolocalisation of PrPSc in scrapie-infected N2a mouse neuroblastoma cells by light and electron microscopy

scientific article published on October 2008

Impact of Training Method on the Robustness of the Visual Assessment of 18F-Florbetaben PET Scans: Results from a Phase-3 Study

scientific article published on 28 January 2016

Impact of the cellular prion protein on amyloid-β and 3PO-tau processing

scientific article

Inactivation of Patched1 in mice leads to development of gastrointestinal stromal-like tumors that express Pdgfrα but not kit.

scientific article

Increase in CD230 (cellular prion protein) fluorescence on blood lymphocytes in bovine spongiform encephalopathy-infected nonhuman primates

scientific article published on 15 October 2009

Increased frequency of positive family history of dementia in sporadic CJD

scientific article published on 05 September 2007

Intravenous injection of beta-amyloid seeds promotes cerebral amyloid angiopathy (CAA).

scientific article published on 5 March 2018

Is Cell Death Primary or Secondary in the Pathophysiology of Idiopathic Parkinson's Disease?

scientific article

Is there a risk of prion-like disease transmission by Alzheimer- or Parkinson-associated protein particles?

scientific article

LPS receptor (CD14): a receptor for phagocytosis of Alzheimer's amyloid peptide.

scientific article published on 27 April 2005

Loss of prion protein leads to age-dependent behavioral abnormalities and changes in cytoskeletal protein expression.

scientific article published on 7 March 2014

Mild expression differences of MECP2 influencing aggressive social behavior

scientific article

Monocyte Subsets and Related Chemokines in Carotid Artery Stenosis and Ischemic Stroke

scientific article published on 23 March 2016

Monocyte/macrophage differentiation in dermatomyositis and polymyositis

scientific article published on 01 August 2004

Morgagnian cataract resulting from a naturally occurring nonsense mutation elucidates a role of CPAMD8 in mammalian lens development

scientific article

Movement disturbances in the differential diagnosis of Creutzfeldt-Jakob disease

scientific article published on 01 February 2009

Myofibrillar disorganization characterizes myopathy of camptocormia in Parkinson's disease

scientific article published on 11 December 2011

Neurodegeneration in Parkinson disease: moving Lewy bodies out of focus

scientific article

Neuroprotective effects of the cellular prion protein in autoimmune optic neuritis

scientific article

Neuropsychological Symptoms in Sporadic Creutzfeldt-Jakob Disease Patients in Germany

scientific article published on 08 June 2017

Occupation-Associated Fatal Limbic Encephalitis Caused by Variegated Squirrel Bornavirus 1, Germany, 2013.

scientific article published in June 2018

Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19

scientific article published on 30 November 2020

Olfactory transmucosal SARS-CoV-2 invasion as port of Central Nervous System entry in COVID-19 patients

scholarly article by Christian Drosten published in 2020

Optimized high-resolution mapping of magnetization transfer (MT) at 3 Tesla for direct visualization of substructures of the human thalamus in clinically feasible measurement time

scientific article published in June 2009

Over-expression of alpha-synuclein in the nervous system enhances axonal degeneration after peripheral nerve lesion in a transgenic mouse strain

scientific article published on 26 May 2010

Overexpression of cellular prion protein alters postischemic Erk1/2 phosphorylation but not Akt phosphorylation and protects against focal cerebral ischemia

scientific article published on 01 January 2008

Partial-Volume Effect Correction Improves Quantitative Analysis of 18F-Florbetaben β-Amyloid PET Scans

scientific article published on 5 November 2015

Patched Knockout Mouse Models of Basal Cell Carcinoma ⬇️

scientific article published on September 13, 2012

Pathological manifestations of Farber disease in a new mouse model

scientific article published on 01 September 2018

Physiological role of the cellular prion protein (PrPc): protein profiling study in two cell culture systems

scientific article

PrPSc spreading patterns in the brain of sheep linked to different prion types ⬇️

scientific article published on February 15, 2011

PrPTSE in muscle-associated lymphatic tissue during the preclinical stage of mice infected orally with bovine spongiform encephalopathy

scientific article published on 17 June 2009

Preclinical deposition of pathological prion protein PrPSc in muscles of hamsters orally exposed to scrapie

scientific article

Preclinical deposition of pathological prion protein in muscle of experimentally infected primates

scientific article

Presence and seeding activity of pathological prion protein (PrP(TSE)) in skeletal muscles of white-tailed deer infected with chronic wasting disease

scientific article

Presynaptic alpha-synuclein aggregates, not Lewy bodies, cause neurodegeneration in dementia with Lewy bodies.

scientific article published in February 2007

Primary Intracranial Manifestation of a Carcinosarcoma

Primary intraspinal primitive neuroectodermal tumor: report of two cases and review of the literature

scientific article published in January 2003

Prion protein helix1 promotes aggregation but is not converted into beta-sheet

scientific article published on 01 October 2006

Progressive loss of a glial potassium channel (KCNJ10) in the spinal cord of the SOD1 (G93A) transgenic mouse model of amyotrophic lateral sclerosis

scientific article published on 21 August 2006

Proteomics Approach to Identify the Interacting Partners of Cellular Prion Protein and Characterization of Rab7a Interaction in Neuronal Cells ⬇️

scientific article published on June 7, 2011

Sall1, sall2, and sall4 are required for neural tube closure in mice

scientific journal article

Screening of innate immune receptors in neurodegenerative diseases: a similar pattern.

scientific article published in October 2007

Selective detection, quantification, and subcellular location of alpha-synuclein aggregates with a protein aggregate filtration assay

scientific article

Serial positron emission tomographic findings in an atypical presentation of fatal familial insomnia

scientific article published in November 2002

Similarities between forms of sheep scrapie and Creutzfeldt-Jakob disease are encoded by distinct prion types

scientific article published on 22 October 2009

Specific visualization of glioma cells in living low-grade tumor tissue

scientific article

Spongiform encephalopathy in siblings with no evidence of protease-resistant prion protein or a mutation in the prion protein gene

scientific article published on 2 April 2013

Sporadic Creutzfeldt-Jakob disease subtype-specific alterations of the brain proteome: impact on Rab3a recycling

scientific article published on 12 December 2012

Sporadic Creutzfeldt-Jakob disease with mesiotemporal hypermetabolism

scientific article published in August 2014

Substantial early, but nonprogressive neuronal loss in multiple sclerosis (MS) spinal cord.

scientific article published in November 2009

Subtype-specific synaptic proteome alterations in sporadic Creutzfeldt-Jakob disease

scientific article published in January 2013

TSPY-LTA transgenic mice develop endocrine tumors of the pituitary and adrenal gland

scientific article published in February 2003

Targeting Chemokine Receptor CXCR4 and Translocator Protein for Characterization of High-Risk Plaque in Carotid Stenosis Ex Vivo

scientific article published on 01 August 2018

Tau protein, Abeta42 and S-100B protein in cerebrospinal fluid of patients with dementia with Lewy bodies

scientific article published on 5 January 2005

The Hedgehog receptor Patched controls lymphoid lineage commitment

scientific article published on 29 May 2007

The Importance of the Hedgehog Signaling Pathway in Tumorigenesis of Spinal and Cranial Chordoma

The Influence of Distinct Regulatory miRNAs of the p15/p16/RB1/E2F Pathway on the Clinical Progression of Glioblastoma Multiforme

scientific article published on 24 July 2019

The cellular prion protein binds copper in vivo

scientific article published in Nature

The real-time quaking-induced conversion assay for detection of human prion disease and study of other protein misfolding diseases

scientific article

The synaptic pathology of alpha-synuclein aggregation in dementia with Lewy bodies, Parkinson's disease and Parkinson's disease dementia

scientific article

Time-point and dosage of gene inactivation determine the tumor spectrum in conditional Ptch knockouts

scientific article published on 25 March 2009

Transcranial direct current stimulation induces polarity-specific changes of cortical blood perfusion in the rat ⬇️

scientific article published on December 11, 2010

Tumor localization of an anti-TGF-β antibody and its effects on gliomas

scientific article published on January 1, 2011

Tumor stroma-derived Wnt5a induces differentiation of basal cell carcinoma of Ptch-mutant mice via CaMKII.

scientific article

Types and Strains: Their Essential Role in Understanding Protein Aggregation in Neurodegenerative Diseases

scientific article

Unexpected high frequency of neurofibroma in the celiac ganglion of German cattle

scientific article published on 17 June 2020

Upregulation of cellular prion protein (PrPc) after focal cerebral ischemia and influence of lesion severity

scientific article published in November 2004

Upregulation of miRNA hsa-miR-342-3p in experimental and idiopathic prion disease

scientific article published on 27 August 2009

Validation and utilization of amended diagnostic criteria in Creutzfeldt-Jakob disease surveillance

scientific article published on 22 June 2018

Widespread expression of erythropoietin receptor in brain and its induction by injury

scientific article published on September 2015

α-Synuclein and tau concentrations in cerebrospinal fluid of patients presenting with parkinsonism: a cohort study

scientific article published on March 2011

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