List of works - Per M Humpert

A 63bp deletion in the promoter of rage correlates with a decreased risk for nephropathy in patients with type 2 diabetes

scientific article

A M55V polymorphism in the SUMO4 gene is associated with a reduced prevalence of diabetic retinopathy in patients with Type 1 diabetes.

scientific article

A mechanism converting psychosocial stress into mononuclear cell activation

scholarly article

A novel nutritional supplement containing amino acids and chromium decreases postprandial glucose response in a randomized, double-blind, placebo-controlled study

scientific article published on 24 June 2020

AGE-modified albumin containing infusion solutions boosts septicaemia and inflammation in experimental peritonitis.

scientific article published on 28 April 2009

Acute hyperglycemia causes intracellular formation of CML and activation of ras, p42/44 MAPK, and nuclear factor kappaB in PBMCs

scientific article published in March 2003

Adult vascular progenitor cells and tissue regeneration in metabolic syndrome

scientific article

Advanced glycation end product receptor-mediated cellular dysfunction

scientific article

Alanine-aminotransferase levels predict impaired glucose tolerance in a worksite population

scientific article published on 24 October 2009

Aryl hydrocarbon receptor interacting protein gene (AIP) mutations are rare in patients with hormone secreting or non-secreting pituitary adenomas

scientific article published on 16 May 2008

Asp299Gly and Thr399Ile genotypes of the TLR4 gene are associated with a reduced prevalence of diabetic neuropathy in patients with type 2 diabetes

scientific article published in January 2004

Association of homozygous SDF-1 3'A genotype with proliferative diabetic retinopathy

scientific article

Association of stromal cell-derived factor 1 genotype with diabetic foot syndrome and macrovascular disease in patients with type 2 diabetes

scientific article published on 01 June 2006

Associations of fetuin-A levels with vascular disease in type 2 diabetes patients with early diabetic nephropathy.

scientific article

C. elegans as model for the study of high glucose- mediated life span reduction

scientific article published on 12 August 2009

Changes in adiponectin multimer distribution in response to atorvastatin treatment in patients with type 2 diabetes

scientific article

Clinical benefit of a short term dietary oatmeal intervention in patients with type 2 diabetes and severe insulin resistance: a pilot study

scientific article

Decreased plasma lipoprotein lipase in hypoadiponectinemia: an association independent of systemic inflammation and insulin resistance

scientific article published in December 2004

Determinants of troponin release in patients with stable coronary artery disease: insights from CT angiography characteristics of atherosclerotic plaque.

scientific article published on 30 September 2010

Diabetes-associated sustained activation of the transcription factor nuclear factor-kappaB

scientific article (publication date: December 2001)

Dietary Intervention with Oatmeal in Patients with uncontrolled Type 2 Diabetes Mellitus - A Crossover Study

scientific article published on 29 August 2018

Echocardiographic phase imaging to predict reverse remodeling after cardiac resynchronization therapy.

scientific article

Effects of stress reduction on cardiovascular risk factors in type 2 diabetes patients with early kidney disease - results of a randomized controlled trial (HEIDIS).

scientific article published on 05 May 2014

Electric muscle stimulation: electric pulses for diabetic polyneuropathy (interview by Dr. Thomas Meissner)

scientific article published in May 2009

Erratum: Corrigendum: Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy

scholarly article published in Nature Medicine

Evaluation of myocardial perfusion and deformation in patients with acute myocardial infarction treated with primary angioplasty and stent placement

scientific article

Evidence of left ventricular contractile asynchrony by echocardiographic phase imaging in patients with type 2 diabetes mellitus and without clinically evident heart disease

scientific article published on 16 October 2006

External electric muscle stimulation improves burning sensations and sleeping disturbances in patients with type 2 diabetes and symptomatic neuropathy

scientific article published on 16 January 2009

Functional polymorphisms of UCP2 and UCP3 are associated with a reduced prevalence of diabetic neuropathy in patients with type 1 diabetes.

scientific article

Glyoxalase-1 prevents mitochondrial protein modification and enhances lifespan in Caenorhabditis elegans

scientific article published on 21 January 2008

Have we understood diabetes? New tasks for diagnosis and therapy

scientific article published in January 2010

High-Mobility Group Box-1 in Ischemia-Reperfusion Injury of the Heart

article

High-molecular weight adiponectin is independently associated with the extent of coronary artery disease in men.

scientific article published on 19 November 2007

Hochfrequente Muskelstimulation zur Behandlung schmerzhafter Neuropathie bei Typ 2 Diabetikern verbessert die mikrovaskuläre Endothelzellfunktion

Impact of autonomic neuropathy on left ventricular function in normotensive type 1 diabetic patients: a tissue Doppler echocardiographic study: response to Karamitsos et al

scientific article published on 01 May 2008

Impaired dexamethasone resorption in two patients with pseudo-Cushing after bariatric surgery: Implications for immunosuppressive treatment

scientific article published on 12 June 2020

Improved vascular function upon pioglitazone treatment in type 2 diabetes is not associated with changes in mononuclear NF-kappaB binding activity

scientific article published on 01 September 2007

Influence of insulin and glargine on outgrowth and number of circulating endothelial progenitor cells in type 2 diabetes patients: a partially double-blind, randomized, three-arm unicenter study

scientific article

Insulin stimulates the clonogenic potential of angiogenic endothelial progenitor cells by IGF-1 receptor-dependent signaling

scientific article

Is diabetes an acquired disorder of reactive glucose metabolites and their intermediates? ⬇️

scientific article published on January 22, 2012

Kidney injury molecule-1 and the loss of kidney function in diabetic nephropathy: a likely causal link in patients with type 1 diabetes

scientific article

Lack of association between polymorphisms of the toll-like receptor 4 gene and cerebral ischemia

scientific article published on 01 July 2004

Left ventricular diastolic function in type 2 diabetes mellitus is associated with myocardial triglyceride content but not with impaired myocardial perfusion reserve ⬇️

scientific article published on November 8, 2011

Levels of three distinct p75 neurotrophin receptor forms found in human plasma are altered in type 2 diabetic patients

scientific article published on 11 May 2007

Linking stress to inflammation

scientific article published on June 2006

Locally applied mononuclear bone marrow cells restore angiogenesis and promote wound healing in a type 2 diabetic patient

scientific article published on 01 October 2005

Long-term treatment of central Cushing's syndrome with rosiglitazone

scientific article published on 01 May 2007

Loss of pain perception in diabetes is dependent on a receptor of the immunoglobulin superfamily

scientific article

Metabolic syndrome in a large chemical company: prevalence in a screened worksite sample

scientific article published on 20 September 2007

Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy

scientific article

NF-kappaB as a molecular link between psychosocial stress and organ dysfunction

scientific article published on 20 August 2004

Neuroprotection and antioxidative effects of Sijunzi Tang Decoction in the nematode Caenorhabditis elegans

New treatments for diabetic neuropathy: Pathogenetically oriented treatment ⬇️

scientific article published on December 1, 2003

Non-invasive diagnostic imaging techniques as a window into the diabetic heart: a review of experimental and clinical data

scientific article

Oxidative stress and glucose metabolism--is there a need to revisit effects of insulin treatment?

scientific article published on 6 January 2010

Plasma sRAGE is independently associated with urinary albumin excretion in type 2 diabetes

scientific article published on 01 May 2006

Posttranslationally modified proteins as mediators of sustained intestinal inflammation

scientific article published on October 2006

Promoter polymorphisms of UCP1, UCP2, and UCP3 are not associated with diabetic microvascular complications in type 2 diabetes

scientific article published on 01 April 2007

Protective Effects of Liraglutide and Linagliptin in C. elegans as a New Model for Glucose-Induced Neurodegeneration

scientific article published on 7 May 2015

Proximal neuropathic lesions in distal symmetric diabetic polyneuropathy: findings of high-resolution magnetic resonance neurography

scientific article

Reactive metabolites and AGE/RAGE-mediated cellular dysfunction affect the aging process: a mini-review

scientific article published on 21 October 2010

Reduction of postprandial hyperglycemia in patients with type 2 diabetes reduces NF-kappaB activation in PBMCs

scientific article

Retinol-binding protein 4 & atherosclerosis: risk factor or innocent bystander?

scientific article

Retinol-binding protein 4 is associated with components of the metabolic syndrome, but not with insulin resistance, in men with type 2 diabetes or coronary artery disease

scientific article published on 18 July 2007

Retinol-binding protein-4 in experimental and clinical metabolic disease

scientific article published on May 2008

Rosiglitazone reduces angiotensin II and advanced glycation end product-dependent sustained nuclear factor-kappaB activation in cultured human proximal tubular epithelial cells

scientific article published on 18 August 2008

SDF-1 genotype influences insulin-dependent mobilization of adult progenitor cells in type 2 diabetes

scientific article published in April 2005

Serum adiponectin levels are an independent predictor of the extent of coronary artery disease in men

scientific article published on 24 April 2006

Soluble RAGE but not endogenous secretory RAGE is associated with albuminuria in patients with type 2 diabetes

scientific article published on 7 March 2007

Strain-encoded cardiac MR during high-dose dobutamine stress testing: comparison to cine imaging and to myocardial tagging.

scientific article published in May 2009

Sustained effects of a mindfulness-based stress-reduction intervention in type 2 diabetic patients: design and first results of a randomized controlled trial (the Heidelberger Diabetes and Stress-study).

scientific article published on 14 February 2012

The -174G>C IL-6 gene promoter polymorphism and diabetic microvascular complications

scientific article published on 12 January 2009

The 20210 G to A prothrombin polymorphism and late complications in type 1 diabetes mellitus

scientific article published on 01 January 1999

The DG10S478 variant in the TCF7L2 gene is not associated with microvascular complications in type 2 diabetes

scientific article published on 10 December 2007

The RAGE pathway: activation and perpetuation in the pathogenesis of diabetic neuropathy

scientific article published on 01 April 2008

Tissue factor as a link between wounding and tissue repair.

scientific article

Toll-like receptor polymorphisms and carotid artery intima-media thickness

scientific article published on 17 May 2007

Total and high-molecular weight adiponectin in relation to metabolic variables at baseline and in response to an exercise treatment program: comparative evaluation of three assays: response to Bluher et al.

scientific article published in July 2007

Understanding RAGE, the receptor for advanced glycation end products

scientific article

Urinary Adiponectin Is an Independent Predictor of Progression to End-Stage Renal Disease in Patients With Type 1 Diabetes and Diabetic Nephropathy

Urinary L-FABP and anaemia: distinct roles of urinary markers in type 2 diabetes

scientific article published on 11 November 2009

Urinary adiponectin excretion: a novel marker for vascular damage in type 2 diabetes

scientific article published on 09 June 2009

Urinary excretion of high molecular weight adiponectin is an independent predictor of decline of renal function in type 2 diabetes

scientific article published on 24 December 2013

Urinary liver-type fatty acid binding protein is an independent predictor of stroke and mortality in individuals with type 1 diabetes

scientific article published on 10 June 2017

Urinary liver-type fatty acid-binding protein and progression of diabetic nephropathy in type 1 diabetes

scientific article published on February 2013

Urinary n-acetyl-beta-d-glucosaminidase excretion: an indicator of neuropathy in type 2 diabetes

scientific article published on 20 September 2013

[AGE-RAGE: a hypothesis or a mechanism?]

scientific article published on 01 August 2004

[Acceptance- and mindfulness-based group intervention in advanced type 2 diabetes patients: therapeutic concept and practical experiences]

scientific article published on 17 May 2010

[The unsolved problem of diabetes mellitus type 2 and associated complications].

scientific article published in May 2009

sRAGE and esRAGE are not associated with peripheral or autonomic neuropathy in type 2 diabetes

scientific article published on 28 November 2007

List of works by Per M Humpert

A 63bp deletion in the promoter of rage correlates with a decreased risk for nephropathy in patients with type 2 diabetes

A M55V polymorphism in the SUMO4 gene is associated with a reduced prevalence of diabetic retinopathy in patients with Type 1 diabetes.

A mechanism converting psychosocial stress into mononuclear cell activation

A novel nutritional supplement containing amino acids and chromium decreases postprandial glucose response in a randomized, double-blind, placebo-controlled study

AGE-modified albumin containing infusion solutions boosts septicaemia and inflammation in experimental peritonitis.

Acute hyperglycemia causes intracellular formation of CML and activation of ras, p42/44 MAPK, and nuclear factor kappaB in PBMCs

Adult vascular progenitor cells and tissue regeneration in metabolic syndrome

Advanced glycation end product receptor-mediated cellular dysfunction

Alanine-aminotransferase levels predict impaired glucose tolerance in a worksite population

Aryl hydrocarbon receptor interacting protein gene (AIP) mutations are rare in patients with hormone secreting or non-secreting pituitary adenomas

Asp299Gly and Thr399Ile genotypes of the TLR4 gene are associated with a reduced prevalence of diabetic neuropathy in patients with type 2 diabetes

Association of homozygous SDF-1 3'A genotype with proliferative diabetic retinopathy

Association of stromal cell-derived factor 1 genotype with diabetic foot syndrome and macrovascular disease in patients with type 2 diabetes

Associations of fetuin-A levels with vascular disease in type 2 diabetes patients with early diabetic nephropathy.

C. elegans as model for the study of high glucose- mediated life span reduction

Changes in adiponectin multimer distribution in response to atorvastatin treatment in patients with type 2 diabetes

Clinical benefit of a short term dietary oatmeal intervention in patients with type 2 diabetes and severe insulin resistance: a pilot study

Decreased plasma lipoprotein lipase in hypoadiponectinemia: an association independent of systemic inflammation and insulin resistance

Determinants of troponin release in patients with stable coronary artery disease: insights from CT angiography characteristics of atherosclerotic plaque.

Diabetes-associated sustained activation of the transcription factor nuclear factor-kappaB

Dietary Intervention with Oatmeal in Patients with uncontrolled Type 2 Diabetes Mellitus - A Crossover Study

Echocardiographic phase imaging to predict reverse remodeling after cardiac resynchronization therapy.

Effects of stress reduction on cardiovascular risk factors in type 2 diabetes patients with early kidney disease - results of a randomized controlled trial (HEIDIS).

Electric muscle stimulation: electric pulses for diabetic polyneuropathy (interview by Dr. Thomas Meissner)

Erratum: Corrigendum: Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy

Evaluation of myocardial perfusion and deformation in patients with acute myocardial infarction treated with primary angioplasty and stent placement

Evidence of left ventricular contractile asynchrony by echocardiographic phase imaging in patients with type 2 diabetes mellitus and without clinically evident heart disease

External electric muscle stimulation improves burning sensations and sleeping disturbances in patients with type 2 diabetes and symptomatic neuropathy

Functional polymorphisms of UCP2 and UCP3 are associated with a reduced prevalence of diabetic neuropathy in patients with type 1 diabetes.

Glyoxalase-1 prevents mitochondrial protein modification and enhances lifespan in Caenorhabditis elegans

Have we understood diabetes? New tasks for diagnosis and therapy

High-Mobility Group Box-1 in Ischemia-Reperfusion Injury of the Heart

High-molecular weight adiponectin is independently associated with the extent of coronary artery disease in men.

Hochfrequente Muskelstimulation zur Behandlung schmerzhafter Neuropathie bei Typ 2 Diabetikern verbessert die mikrovaskuläre Endothelzellfunktion

Impact of autonomic neuropathy on left ventricular function in normotensive type 1 diabetic patients: a tissue Doppler echocardiographic study: response to Karamitsos et al

Impaired dexamethasone resorption in two patients with pseudo-Cushing after bariatric surgery: Implications for immunosuppressive treatment

Improved vascular function upon pioglitazone treatment in type 2 diabetes is not associated with changes in mononuclear NF-kappaB binding activity

Influence of insulin and glargine on outgrowth and number of circulating endothelial progenitor cells in type 2 diabetes patients: a partially double-blind, randomized, three-arm unicenter study

Insulin stimulates the clonogenic potential of angiogenic endothelial progenitor cells by IGF-1 receptor-dependent signaling

Is diabetes an acquired disorder of reactive glucose metabolites and their intermediates? ⬇️

Kidney injury molecule-1 and the loss of kidney function in diabetic nephropathy: a likely causal link in patients with type 1 diabetes

Lack of association between polymorphisms of the toll-like receptor 4 gene and cerebral ischemia

Left ventricular diastolic function in type 2 diabetes mellitus is associated with myocardial triglyceride content but not with impaired myocardial perfusion reserve ⬇️

Levels of three distinct p75 neurotrophin receptor forms found in human plasma are altered in type 2 diabetic patients

Linking stress to inflammation

Locally applied mononuclear bone marrow cells restore angiogenesis and promote wound healing in a type 2 diabetic patient

Long-term treatment of central Cushing's syndrome with rosiglitazone

Loss of pain perception in diabetes is dependent on a receptor of the immunoglobulin superfamily

Metabolic syndrome in a large chemical company: prevalence in a screened worksite sample

Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy

NF-kappaB as a molecular link between psychosocial stress and organ dysfunction

Neuroprotection and antioxidative effects of Sijunzi Tang Decoction in the nematode Caenorhabditis elegans

New treatments for diabetic neuropathy: Pathogenetically oriented treatment ⬇️

Non-invasive diagnostic imaging techniques as a window into the diabetic heart: a review of experimental and clinical data

Oxidative stress and glucose metabolism--is there a need to revisit effects of insulin treatment?

Plasma sRAGE is independently associated with urinary albumin excretion in type 2 diabetes

Posttranslationally modified proteins as mediators of sustained intestinal inflammation

Promoter polymorphisms of UCP1, UCP2, and UCP3 are not associated with diabetic microvascular complications in type 2 diabetes

Protective Effects of Liraglutide and Linagliptin in C. elegans as a New Model for Glucose-Induced Neurodegeneration

Proximal neuropathic lesions in distal symmetric diabetic polyneuropathy: findings of high-resolution magnetic resonance neurography

Reactive metabolites and AGE/RAGE-mediated cellular dysfunction affect the aging process: a mini-review

Reduction of postprandial hyperglycemia in patients with type 2 diabetes reduces NF-kappaB activation in PBMCs

Retinol-binding protein 4 & atherosclerosis: risk factor or innocent bystander?

Retinol-binding protein 4 is associated with components of the metabolic syndrome, but not with insulin resistance, in men with type 2 diabetes or coronary artery disease

Retinol-binding protein-4 in experimental and clinical metabolic disease

Rosiglitazone reduces angiotensin II and advanced glycation end product-dependent sustained nuclear factor-kappaB activation in cultured human proximal tubular epithelial cells

SDF-1 genotype influences insulin-dependent mobilization of adult progenitor cells in type 2 diabetes

Serum adiponectin levels are an independent predictor of the extent of coronary artery disease in men

Soluble RAGE but not endogenous secretory RAGE is associated with albuminuria in patients with type 2 diabetes

Strain-encoded cardiac MR during high-dose dobutamine stress testing: comparison to cine imaging and to myocardial tagging.

Sustained effects of a mindfulness-based stress-reduction intervention in type 2 diabetic patients: design and first results of a randomized controlled trial (the Heidelberger Diabetes and Stress-study).

The -174G>C IL-6 gene promoter polymorphism and diabetic microvascular complications

The 20210 G to A prothrombin polymorphism and late complications in type 1 diabetes mellitus

The DG10S478 variant in the TCF7L2 gene is not associated with microvascular complications in type 2 diabetes

The RAGE pathway: activation and perpetuation in the pathogenesis of diabetic neuropathy

Tissue factor as a link between wounding and tissue repair.

Toll-like receptor polymorphisms and carotid artery intima-media thickness

Total and high-molecular weight adiponectin in relation to metabolic variables at baseline and in response to an exercise treatment program: comparative evaluation of three assays: response to Bluher et al.

Understanding RAGE, the receptor for advanced glycation end products