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List of works by Bert Schepens

A GFP expressing influenza A virus to report in vivo tropism and protection by a matrix protein 2 ectodomain-specific monoclonal antibody

scientific article published on 27 March 2015

A Respiratory Syncytial Virus vaccine based on the Small Hydrophobic protein ectodomain presented with a novel lipid-based formulation is highly immunogenic and safe in adults: a first-in-humans study

scientific article published on 30 March 2018

A two-amino acid mutation in murine IgA enables downstream processing and purification on staphylococcal superantigen-like protein 7

scientific article published on 13 February 2019

Antiserum against the conserved nine amino acid N-terminal peptide of influenza A virus matrix protein 2 is not immunoprotective ⬇️

scientific article published on October 21, 2010

Bispecific T cell engaging antibody constructs targeting a universally conserved part of the viral M2 ectodomain cure and prevent influenza A virus infection

scientific article published on 28 February 2017

CD8+ T cell immunity against human respiratory syncytial virus

scientific article published on 16 September 2014

Clinical Potential of Prefusion RSV F-specific Antibodies.

scientific article

Corrigendum: Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state

scientific article published on 29 November 2017

Crystal Structure of the Conserved Amino Terminus of the Extracellular Domain of Matrix Protein 2 of Influenza A Virus Gripped by an Antibody

scientific article

Developing 3D SEM in a broad biological context

scientific article published on 26 January 2015

Evaluation of the protective potential of antibody and T cell responses elicited by a novel preventative vaccine towards respiratory syncytial virus small hydrophobic protein

scientific article published on 12 June 2020

GM-CSF treatment prevents respiratory syncytial virus-induced pulmonary exacerbation responses in postallergic mice by stimulating alveolar macrophage maturation

scientific article

Hepatitis B core–based virus–like particles to present heterologous epitopes ⬇️

scientific article published on February 1, 2013

Hierarchical and Redundant Roles of Activating FcγRs in Protection against Influenza Disease by M2e-Specific IgG1 and IgG2a Antibodies

scientific article published on 11 January 2017

Identification of polymorphisms in the ovine Shadow of prion protein (SPRN) gene and assessment of their effect on promoter activity and susceptibility for classical scrapie

scientific article published on 16 November 2009

IgG3 Snitcher of RSV Infections in the Very Young

scientific article published on 30 January 2017

Influenza-binding sialylated polymer coated gold nanoparticles prepared via RAFT polymerization and reductive amination

scientific article published on 29 January 2016

Interferon-Inducible Protein Mx1 Inhibits Influenza Virus by Interfering with Functional Viral Ribonucleoprotein Complex Assembly ⬇️

scientific article published on September 26, 2012

Intranodal administration of mRNA encoding nucleoprotein provides cross-strain immunity against influenza in mice

scientific article published on 25 July 2019

Llama-derived single domain antibodies to build multivalent, superpotent and broadened neutralizing anti-viral molecules

scientific article (publication date: April 2011)

Long-Lasting Cross-Protection Against Influenza A by Neuraminidase and M2e-based immunization strategies

scientific article

M2-based influenza vaccines: recent advances and clinical potential

scientific article published on 22 September 2016

M2e-based universal influenza A vaccine

scientific article

M2e-displaying virus-like particles with associated RNA promote T helper 1 type adaptive immunity against influenza A.

scientific article

Nanobodies with in vitro neutralizing activity protect mice against H5N1 influenza virus infection

scientific article

Nanobodies® Specific for Respiratory Syncytial Virus Fusion Protein Protect Against Infection by Inhibition of Fusion ⬇️

scientific article published on October 12, 2011

Nanobodies®: New ammunition to battle viruses ⬇️

scientific article published on September 10, 2011

Natural and long-lasting cellular immune responses against influenza in the M2e-immune host

scientific article

Passively transferred M2e-specific monoclonal antibody reduces influenza A virus transmission in mice

scientific article published on 01 September 2018

Phosphoproteomics to Characterize Host Response During Influenza A Virus Infection of Human Macrophages

scientific article published on 2 August 2016

Potent anti-viral vaccine adjuvant based on pH-degradable nanogels with covalently linked small molecule imidazoquinoline TLR7/8 agonist

scientific article

Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state.

scientific article published on 13 February 2017

Protection and mechanism of action of a novel human respiratory syncytial virus vaccine candidate based on the extracellular domain of small hydrophobic protein

scientific article

Recombinant Influenza Virus Carrying the Respiratory Syncytial Virus (RSV) F 85-93 CTL Epitope Reduces RSV Replication in Mice ⬇️

scientific article published on January 9, 2013

Regulation of kynurenine biosynthesis during influenza virus infection.

scientific article published on 18 November 2016

Removal of the N-Glycosylation Sequon at Position N116 Located in p27 of the Respiratory Syncytial Virus Fusion Protein Elicits Enhanced Antibody Responses after DNA Immunization

article

Respiratory syncytial virus nonstructural proteins 1 and 2: Exceptional disrupters of innate immune responses

scientific article published on 17 October 2019

STAT2 signaling restricts viral dissemination but drives severe pneumonia in SARS-CoV-2 infected hamsters

scientific article published on 17 November 2020

Scop3D: three-dimensional visualization of sequence conservation

scientific article published on 3 March 2015

Selective Engagement of FcγRIV by a M2e-Specific Single Domain Antibody Construct Protects Against Influenza A Virus Infection

scientific article published on 12 December 2019

Single-Domain Antibodies and Their Formatting to Combat Viral Infections

scientific article published on 20 December 2018

Single-domain antibodies targeting neuraminidase protect against an H5N1 influenza virus challenge

scientific article published on 14 May 2014

Small hydrophobic protein of respiratory syncytial virus as a novel vaccine antigen

scientific article

Species Specificity of Type III Interferon Activity and Development of a Sensitive Luciferase-Based Bioassay for Quantitation of Mouse Interferon-λ

scientific article published on 18 October 2018

Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies

scientific article published on 29 April 2020

Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies

scientific article published on 01 June 2020

Structural Basis for Potent Neutralization of Betacoronaviruses by Single-domain Camelid Antibodies

scientific article (preprint)

Structure of the extracellular domain of matrix protein 2 of influenza A virus in complex with a protective monoclonal antibody

scientific article published on 21 January 2015

Super-resolution microscopy reveals significant impact of M2e-specific monoclonal antibodies on influenza A virus filament formation at the host cell surface

scientific article published on 14 March 2019

The C terminus of NS1 protein of influenza A/WSN/1933(H1N1) virus modulates antiviral responses in infected human macrophages and mice.

scientific article published on May 2015

Transiently Thermoresponsive Acetal Polymers for Safe and Effective Administration of Amphotericin B as a Vaccine Adjuvant.

scientific article published on 26 November 2017

Vaccination with influenza hemagglutinin-loaded ceramic nanoporous microneedle arrays induces protective immune responses

scientific article published on 05 February 2019

Vaccine options for influenza: thinking small

scientific article

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