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List of works by Dhananjay Pal

A comprehensive insight on ocular pharmacokinetics

scientific article published on 31 October 2016

Activity of a sodium-dependent vitamin C transporter (SVCT) in MDCK-MDR1 cells and mechanism of ascorbate uptake

scientific article

Amino Acid Prodrugs: An Approach to Improve the Absorption of HIV-1 Protease Inhibitor, Lopinavir

scientific article

Amino acid prodrug of quinidine: an approach to circumvent P-glycoprotein mediated cellular efflux

scientific article published on 17 January 2014

Binary and ternary combinations of anti-HIV protease inhibitors: effect on gene expression and functional activity of CYP3A4 and efflux transporters

scientific article published on January 2014

Biotin uptake and cellular translocation in human derived retinoblastoma cell line (Y-79): a role of hSMVT system

scientific article published on 3 February 2006

Biotin uptake by T47D breast cancer cells: functional and molecular evidence of sodium-dependent multivitamin transporter (SMVT).

scientific article

Biotin uptake by rabbit corneal epithelial cells: role of sodium-dependent multivitamin transporter (SMVT).

scientific article

Both P-gp and MRP2 mediate transport of Lopinavir, a protease inhibitor

scientific article

Carrier mediated uptake of L-tyrosine and its competitive inhibition by model tyrosine linked compounds in a rabbit corneal cell line (SIRC)--strategy for the design of transporter/receptor targeted prodrugs

scientific article published on October 2002

Circumventing P-glycoprotein-mediated cellular efflux of quinidine by prodrug derivatization

scientific article published on July 2004

Circumvention of P-gp and MRP2 mediated efflux of lopinavir by a histidine based dipeptide prodrug

scientific article published on 16 August 2016

Clinically relevant drug-drug interactions between antiretrovirals and antifungals

scientific article published on 12 February 2014

Co-administration strategy to enhance brain accumulation of vandetanib by modulating P-glycoprotein (P-gp/Abcb1) and breast cancer resistance protein (Bcrp1/Abcg2) mediated efflux with m-TOR inhibitors.

scientific article published on 23 May 2012

Controlled delivery of ganciclovir to the retina with drug-loaded Poly(d,L-lactide-co-glycolide) (PLGA) microspheres dispersed in PLGA-PEG-PLGA Gel: a novel intravitreal delivery system for the treatment of cytomegalovirus retinitis

scientific article published in June 2007

Cotransport of macrolide and fluoroquinolones, a beneficial interaction reversing P-glycoprotein efflux

scientific article

Differential Expression of Folate Receptor-Alpha, Sodium-Dependent Multivitamin Transporter, and Amino Acid Transporter (B(0, +)) in Human Retinoblastoma (Y-79) and Retinal Pigment Epithelial (ARPE-19) Cell Lines ⬇️

scientific article published on February 3, 2012

Differential effect of P-gp and MRP2 on cellular translocation of gemifloxacin

scientific article

Dipeptide prodrug approach to evade efflux pumps and CYP3A4 metabolism of lopinavir

scientific article published on 26 September 2014

Discovery of novel inhibitors for the treatment of glaucoma

scientific article

Effect of HEPES buffer on the uptake and transport of P-glycoprotein substrates and large neutral amino acids

scientific article

Effect of short term and chronic administration of Sutherlandia frutescens on pharmacokinetics of nevirapine in rats.

scientific article

Efflux transporters- and cytochrome P-450-mediated interactions between drugs of abuse and antiretrovirals ⬇️

scientific article published on May 23, 2011

Enhanced brain accumulation of pazopanib by modulating P-gp and Bcrp1 mediated efflux with canertinib or erlotinib.

scientific article published on 9 June 2012

Enhanced corneal absorption of erythromycin by modulating P-glycoprotein and MRP mediated efflux with corticosteroids

scientific article

Enhanced transport of a novel anti-HIV agent--cosalane and its congeners across human intestinal epithelial (Caco-2) cell monolayers

scientific article published in January 2003

Evasion of P-gp mediated cellular efflux and permeability enhancement of HIV-protease inhibitor saquinavir by prodrug modification

scientific article published on October 2005

Functional activity of a monocarboxylate transporter, MCT1, in the human retinal pigmented epithelium cell line, ARPE-19.

scientific article

Functional and molecular aspects of biotin uptake via SMVT in human corneal epithelial (HCEC) and retinal pigment epithelial (D407) cells

scientific article

Functional characterization and molecular expression of large neutral amino acid transporter (LAT1) in human prostate cancer cells ⬇️

scientific article published on December 24, 2012

Functional characterization and molecular identification of vitamin C transporter (SVCT2) in human corneal epithelial (HCEC) and retinal pigment epithelial (D407) cells

scientific article

Functional characterization of peptide transporters in MDCKII-MDR1 cell line as a model for oral absorption studies

scientific article

Functional characterization of sodium-dependent multivitamin transporter in MDCK-MDR1 cells and its utilization as a target for drug delivery

scientific article

Functional differences in nucleoside and nucleobase transporters expressed on the rabbit corneal epithelial cell line (SIRC) and isolated rabbit cornea

scientific article published on January 2003

Honokiol inhibits HIF pathway and hypoxia-induced expression of histone lysine demethylases ⬇️

scientific article published on May 3, 2012

How are we improving the delivery to back of the eye? Advances and challenges of novel therapeutic approaches

scientific article published on 14 December 2016

Hypoxia induced expression of histone lysine demethylases: Implications in oxygen-dependent retinal neovascular diseases ⬇️

scientific article published on October 20, 2011

Identification and characterization of a Na+-dependent neutral amino acid transporter, ASCT1, in rabbit corneal epithelial cell culture and rabbit cornea

scientific article

Identification and functional characterization of a Na(+)-independent large neutral amino acid transporter (LAT2) on ARPE-19 cells

scientific article published on May 2004

Identification and functional characterization of a Na+-independent large neutral amino acid transporter, LAT1, in human and rabbit cornea

scientific article

Identification and functional characterization of breast cancer resistance protein in human bronchial epithelial cells (Calu-3).

scientific article published on 25 September 2009

Identification and functional characterization of riboflavin transporter in human-derived retinoblastoma cell line (Y-79): mechanisms of cellular uptake and translocation

scientific article published on August 2005

Identification and functional expression of a carrier-mediated riboflavin transport system on rabbit corneal epithelium.

scientific article published in October 2006

Identification of a Na+-dependent cationic and neutral amino acid transporter, B(0,+), in human and rabbit cornea

scientific article published in September 2004

In vitro interaction of the HIV protease inhibitor ritonavir with herbal constituents: changes in P-gp and CYP3A4 activity

scientific article

In vitro moxifloxacin drug interaction with chemotherapeutics: implications for retinoblastoma management

scientific article published on 22 October 2013

Influence of overexpression of efflux proteins on the function and gene expression of endogenous peptide transporters in MDR-transfected MDCKII cell lines ⬇️

scientific article published on December 20, 2012

Inhibition of OATP-1B1 and OATP-1B3 by tyrosine kinase inhibitors

scientific article (publication date: 2014)

Interaction Studies of Resolvin E1 Analog (RX-10045) with Efflux Transporters

scientific article

Interaction of gatifloxacin with efflux transporters: a possible mechanism for drug resistance

scientific article

Interaction of ocular hypotensive agents (PGF2 alpha analogs-bimatoprost, latanoprost, and travoprost) with MDR efflux pumps on the rabbit cornea

scientific article

Long-term delivery of protein and peptide therapeutics for cancer therapies

scientific article published on 16 September 2019

Mechanism of L-ascorbic acid uptake by rabbit corneal epithelial cells: evidence for the involvement of sodium-dependent vitamin C transporter 2.

scientific article published on June 2006

Mechanism of ganciclovir uptake by rabbit retina and human retinal pigmented epithelium cell line ARPE-19.

scientific article

Mechanisms of drug resistance in cancer chemotherapy: coordinated role and regulation of efflux transporters and metabolizing enzymes

scientific article published on January 2013

Mitochondrial localization of P-glycoprotein and peptide transporters in corneal epithelial cells – Novel strategies for intracellular drug targeting ⬇️

scientific article published on October 29, 2012

Molecular and functional characterization of riboflavin specific transport system in rat brain capillary endothelial cells ⬇️

scientific article published on June 7, 2012

Molecular evidence and functional expression of P-glycoprotein (MDR1) in human and rabbit cornea and corneal epithelial cell lines

scientific article

Molecular evidence and functional expression of a novel drug efflux pump (ABCC2) in human corneal epithelium and rabbit cornea and its role in ocular drug efflux

scientific article

Molecular expression and functional activity of efflux and influx transporters in hypoxia induced retinal pigment epithelial cells

scientific article published on July 2013

Molecular expression and functional activity of vitamin C specific transport system (SVCT2) in human breast cancer cells.

scientific article

Molecular expression and functional evidence of a drug efflux pump (BCRP) in human corneal epithelial cells

scientific article published on January 2009

Monocarboxylate transporter mediated uptake of moxifloxacin on human retinal pigmented epithelium cells

scientific article published on September 2013

Multi-Layered Nanomicelles as Self-Assembled Nanocarrier Systems for Ocular Peptide Delivery

scientific article published on 09 January 2019

Nanomicellar Topical Aqueous Drop Formulation of Rapamycin for Back-of-the-Eye Delivery

scientific article published on 26 November 2014

Nanoparticle-Based Topical Ophthalmic Gel Formulation for Sustained Release of Hydrocortisone Butyrate

scientific article

Nanoparticle-based topical ophthalmic formulation for sustained release of stereoisomeric dipeptide prodrugs of ganciclovir

scientific article published on 7 January 2015

Novel Biotinylated Lipid Prodrugs of Acyclovir for the Treatment of Herpetic Keratitis (HK): Transporter Recognition, Tissue Stability and Antiviral Activity ⬇️

scientific article published on 09 May 2013

Novel L-Dopa and dopamine prodrugs containing a 2-phenyl-imidazopyridine moiety.

scientific article published on 3 April 2007

Novel Random Triblock Copolymers for Sustained Delivery of Macromolecules for the Treatment of Ocular Diseases

scientific article published on 10 October 2018

Novel delivery approaches for cancer therapeutics.

scientific article

Novel nanoparticulate gel formulations of steroids for the treatment of macular edema

scientific article

Novel pentablock copolymer-based nanoparticulate systems for sustained protein delivery

scientific article published on 16 October 2014

Novel thermosensitive pentablock copolymers for sustained delivery of proteins in the treatment of posterior segment diseases

scientific article published on January 2014

Ocular Drug Delivery: Present Innovations and Future Challenges

scientific article published on 09 May 2019

Ocular Pharmacokinetics of a Topical Ophthalmic Nanomicellar Solution of Cyclosporine (Cequa®) for Dry Eye Disease

scientific article published on 07 January 2019

Ocular Sustained Release Nanoparticles Containing Stereoisomeric Dipeptide Prodrugs of Acyclovir ⬇️

scientific article published on April 1, 2011

Ocular delivery of proteins and peptides: challenges and novel formulation approaches

scientific article published on 12 January 2018

Optimization of novel pentablock copolymer based composite formulation for sustained delivery of peptide/protein in the treatment of ocular diseases

scientific article published on 11 March 2016

PSMA Antibody-Conjugated Pentablock Copolymer Nanomicellar Formulation for Targeted Delivery to Prostate Cancer

scientific article published on 27 August 2018

Peptide prodrugs: improved oral absorption of lopinavir, a HIV protease inhibitor

scientific article

Preparation and characterization of lutein loaded folate conjugated polymeric nanoparticles

scientific article published on 26 August 2020

Prodrug approach to improve absorption of prednisolone

scientific article

Prodrugs and nanomicelles to overcome ocular barriers for drug penetration

scientific article published on 30 July 2020

Recent perspectives on the delivery of biologics to back of the eye.

scientific article

Role of OATP-1B1 and/or OATP-1B3 in hepatic disposition of tyrosine kinase inhibitors

scientific article (publication date: 2014)

Role of membrane transporters and metabolizing enzymes in ocular drug delivery

scientific article published on January 2014

Self-Assembling Tacrolimus Nanomicelles for Retinal Drug Delivery

scientific article published on 10 November 2020

Self-Assembling Topical Nanomicellar Formulation to Improve Curcumin Absorption Across Ocular Tissues

scientific article published on 17 July 2019

Statistical design for formulation optimization of hydrocortisone butyrate-loaded PLGA nanoparticles

scientific article

Stereoselective Evasion of P-glycoprotein, Cytochrome P450 3A, and Hydrolases by Peptide Prodrug Modification of Saquinavir ⬇️

scientific article published on May 18, 2012

Strategic Pentablock Copolymer Nanomicellar Formulation for Paclitaxel Delivery System

scientific article published on 15 August 2018

Study of the extent of ocular absorption of acetazolamide from a developed niosomal formulation, by microdialysis sampling of aqueous humor

scientific article published on 19 January 2007

Synthesis, physicochemical properties and antiviral activities of ester prodrugs of ganciclovir

scientific article published on 19 October 2005

Tailor-made pentablock copolymer based formulation for sustained ocular delivery of protein therapeutics

scientific article published on 22 June 2014

Targeted lipid based drug conjugates: a novel strategy for drug delivery.

scientific article

Targeting SVCT for enhanced drug absorption: synthesis and in vitro evaluation of a novel vitamin C conjugated prodrug of saquinavir.

scientific article published on 7 May 2011

Topical Formulation of Self-Assembled Antiviral Prodrug Nanomicelles for Targeted Retinal Delivery.

scientific article

Transfected MDCK cell line with enhanced expression of CYP3A4 and P-glycoprotein as a model to study their role in drug transport and metabolism.

scientific article

Transport of HIV-protease inhibitors across 1 alpha,25di-hydroxy vitamin D3-treated Calu-3 cell monolayers: modulation of P-glycoprotein activity

scientific article published on November 2002

Transporter effects on cell permeability in drug delivery

scientific article published on 22 July 2016

Uptake and Permeability Studies to Delineate the Role of Efflux Transporters.

scientific article published in January 2016

Uptake and bioconversion of stereoisomeric dipeptide prodrugs of ganciclovir by nanoparticulate carriers in corneal epithelial cells

scientific article published on 16 March 2015

Vitreal pharmacokinetics of biotinylated ganciclovir: role of sodium-dependent multivitamin transporter expressed on retina

scientific article

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