List of works - Nichole R Klatt

A summary of the second annual HIV Microbiome workshop.

scientific article published on 13 September 2017

Analysis of the In Vivo Turnover of CD4+ T-Cell Subsets in Chronically SIV-Infected Sooty Mangabeys

scientific article

Availability of activated CD4+ T cells dictates the level of viremia in naturally SIV-infected sooty mangabeys

scientific article published on June 2008

Bone marrow-based homeostatic proliferation of mature T cells in nonhuman primates: implications for AIDS pathogenesis

scientific article published on October 2008

CD127 and CD25 expression defines CD4+ T cell subsets that are differentially depleted during HIV infection

scientific article published on April 2008

CD4 + T Cells and HIV: A Paradoxical Pas de Deux ⬇️

scientific article published on February 29, 2012

CD4 downregulation by memory CD4+ T cells in vivo renders African green monkeys resistant to progressive SIVagm infection

scientific article published on 14 June 2009

CD4-like immunological function by CD4- T cells in multiple natural hosts of simian immunodeficiency virus

scientific article

CD8+ lymphocytes control viral replication in SIVmac239-infected rhesus macaques without decreasing the lifespan of productively infected cells

scientific article

Damaged intestinal epithelial integrity linked to microbial translocation in pathogenic simian immunodeficiency virus infections

scientific article

Depletion of CD4⁺ T cells abrogates post-peak decline of viremia in SIV-infected rhesus macaques

scientific article

Downregulation of robust acute type I interferon responses distinguishes nonpathogenic simian immunodeficiency virus (SIV) infection of natural hosts from pathogenic SIV infection of rhesus macaques

scientific article

Dynamics of simian immunodeficiency virus SIVmac239 infection in pigtail macaques

scientific article published on 16 November 2011

Effects of Fecal Microbial Transplantation on Microbiome and Immunity in Simian Immunodeficiency Virus-Infected Macaques

scientific article

Effects of persistent modulation of intestinal microbiota on SIV/HIV vaccination in rhesus macaques

scientific article published on 11 March 2021

Enhancement of Microbiota in Healthy Macaques Results in Beneficial Modulation of Mucosal and Systemic Immune Function

scientific article published on 29 January 2016

Experimental colitis in SIV-uninfected rhesus macaques recapitulates important features of pathogenic SIV infection

scientific article

Global genomic analysis reveals rapid control of a robust innate response in SIV-infected sooty mangabeys

scientific article published on December 2009

Gut-Resident Lactobacillus Abundance Associates with IDO1 Inhibition and Th17 Dynamics in SIV-Infected Macaques

scientific article published on 11 November 2015

HIV and mucosal barrier interactions: consequences for transmission and pathogenesis

scientific article published on 4 July 2015

HIV transmission. Selection bias at the heterosexual HIV-1 transmission bottleneck

scientific article

HIV vaccine trial exploits a dual and central role for innate immunity.

scientific article

High production rates sustain in vivo levels of PD-1high simian immunodeficiency virus-specific CD8 T cells in the face of rapid clearance

scientific article published on 03 July 2013

Homeostatic cytokines induce CD4 downregulation in African green monkeys independently of antigen exposure to generate simian immunodeficiency virus-resistant CD8αα T cells

scientific article

Hypercytotoxicity and rapid loss of NKp44+ innate lymphoid cells during acute SIV infection

scientific article (publication date: December 2014)

Immune activation and HIV persistence: implications for curative approaches to HIV infection

scientific article

Laparoscopic Technique for Serial Collection of Liver and Mesenteric Lymph Nodes in Macaques

scientific article published on 2 May 2017

Limited HIV infection of central memory and stem cell memory CD4+ T cells is associated with lack of progression in viremic individuals

scientific article

Lineage-specific T-cell reconstitution following in vivo CD4+ and CD8+ lymphocyte depletion in nonhuman primates

scientific article

Liver macrophage-associated inflammation correlates with SIV burden and is substantially reduced following cART.

scientific article published on 21 February 2018

Loss of immune homeostasis dictates SHIV rebound after stem-cell transplantation

scientific article published on 23 February 2017

Mechanisms underlying γδ T-cell subset perturbations in SIV-infected Asian rhesus macaques

scientific article

Microbial translocation and microbiome dysbiosis in HIV-associated immune activation

scientific article published on 16 December 2015

Microbial translocation, immune activation, and HIV disease

scientific article published on 11 October 2012

Microbiome Composition and Function Drives Wound-Healing Impairment in the Female Genital Tract

scientific article

Probiotic/prebiotic supplementation of antiretrovirals improves gastrointestinal immunity in SIV-infected macaques.

scientific article published on 16 January 2013

Quantitative modeling predicts mechanistic links between pre-treatment microbiome composition and metronidazole efficacy in bacterial vaginosis

scientific article published on 01 December 2020

Rate of AIDS progression is associated with gastrointestinal dysfunction in simian immunodeficiency virus-infected pigtail macaques

scientific article published on 11 February 2013

Reconstitution of CD4 T cells in bronchoalveolar lavage fluid after initiation of highly active antiretroviral therapy

scientific article

Residual immune dysregulation syndrome in treated HIV infection

scientific article

SIV infection of rhesus macaques results in dysfunctional T- and B-cell responses to neo and recall Leishmania major vaccination.

scientific article published on 29 September 2011

SIV-induced Translocation of Bacterial Products in the Liver Mobilizes Myeloid Dendritic and Natural Killer Cells Associated With Liver Damage

scientific article

Severe depletion of mucosal CD4+ T cells in AIDS-free simian immunodeficiency virus-infected sooty mangabeys

scientific article published on September 2007

Short-lived infected cells support virus replication in sooty mangabeys naturally infected with simian immunodeficiency virus: implications for AIDS pathogenesis

scientific article

Superior T memory stem cell persistence supports long-lived T cell memory

scientific article published on 2 January 2013

Th17 cell dynamics in HIV infection

scientific article published on March 2010

Transcriptional Profiling of Experimental CD8+Lymphocyte Depletion in Rhesus Macaques Infected with Simian Immunodeficiency Virus SIVmac239 ⬇️

scientific article published on October 24, 2012

Vaginal bacteria modify HIV tenofovir microbicide efficacy in African women

scientific article

Viral CTL Escape Mutants Are Generated in Lymph Nodes and Subsequently Become Fixed in Plasma and Rectal Mucosa during Acute SIV Infection of Macaques ⬇️

scientific article (publication date: May 2011)

Why don't CD8+ T cells reduce the lifespan of SIV-infected cells in vivo?

scientific article published on 29 September 2011

List of works by Nichole R Klatt

A summary of the second annual HIV Microbiome workshop.

Analysis of the In Vivo Turnover of CD4+ T-Cell Subsets in Chronically SIV-Infected Sooty Mangabeys

Availability of activated CD4+ T cells dictates the level of viremia in naturally SIV-infected sooty mangabeys

Bone marrow-based homeostatic proliferation of mature T cells in nonhuman primates: implications for AIDS pathogenesis

CD127 and CD25 expression defines CD4+ T cell subsets that are differentially depleted during HIV infection

CD4 + T Cells and HIV: A Paradoxical Pas de Deux ⬇️

CD4 downregulation by memory CD4+ T cells in vivo renders African green monkeys resistant to progressive SIVagm infection

CD4-like immunological function by CD4- T cells in multiple natural hosts of simian immunodeficiency virus

CD8+ lymphocytes control viral replication in SIVmac239-infected rhesus macaques without decreasing the lifespan of productively infected cells

Damaged intestinal epithelial integrity linked to microbial translocation in pathogenic simian immunodeficiency virus infections

Depletion of CD4⁺ T cells abrogates post-peak decline of viremia in SIV-infected rhesus macaques

Downregulation of robust acute type I interferon responses distinguishes nonpathogenic simian immunodeficiency virus (SIV) infection of natural hosts from pathogenic SIV infection of rhesus macaques

Dynamics of simian immunodeficiency virus SIVmac239 infection in pigtail macaques

Effects of Fecal Microbial Transplantation on Microbiome and Immunity in Simian Immunodeficiency Virus-Infected Macaques

Effects of persistent modulation of intestinal microbiota on SIV/HIV vaccination in rhesus macaques

Enhancement of Microbiota in Healthy Macaques Results in Beneficial Modulation of Mucosal and Systemic Immune Function

Experimental colitis in SIV-uninfected rhesus macaques recapitulates important features of pathogenic SIV infection

Global genomic analysis reveals rapid control of a robust innate response in SIV-infected sooty mangabeys

Gut-Resident Lactobacillus Abundance Associates with IDO1 Inhibition and Th17 Dynamics in SIV-Infected Macaques

HIV and mucosal barrier interactions: consequences for transmission and pathogenesis

HIV transmission. Selection bias at the heterosexual HIV-1 transmission bottleneck

HIV vaccine trial exploits a dual and central role for innate immunity.

High production rates sustain in vivo levels of PD-1high simian immunodeficiency virus-specific CD8 T cells in the face of rapid clearance

Homeostatic cytokines induce CD4 downregulation in African green monkeys independently of antigen exposure to generate simian immunodeficiency virus-resistant CD8αα T cells

Hypercytotoxicity and rapid loss of NKp44+ innate lymphoid cells during acute SIV infection

Immune activation and HIV persistence: implications for curative approaches to HIV infection

Laparoscopic Technique for Serial Collection of Liver and Mesenteric Lymph Nodes in Macaques

Limited HIV infection of central memory and stem cell memory CD4+ T cells is associated with lack of progression in viremic individuals

Lineage-specific T-cell reconstitution following in vivo CD4+ and CD8+ lymphocyte depletion in nonhuman primates

Liver macrophage-associated inflammation correlates with SIV burden and is substantially reduced following cART.

Loss of immune homeostasis dictates SHIV rebound after stem-cell transplantation

Mechanisms underlying γδ T-cell subset perturbations in SIV-infected Asian rhesus macaques

Microbial translocation and microbiome dysbiosis in HIV-associated immune activation

Microbial translocation, immune activation, and HIV disease

Microbiome Composition and Function Drives Wound-Healing Impairment in the Female Genital Tract

Probiotic/prebiotic supplementation of antiretrovirals improves gastrointestinal immunity in SIV-infected macaques.

Quantitative modeling predicts mechanistic links between pre-treatment microbiome composition and metronidazole efficacy in bacterial vaginosis

Rate of AIDS progression is associated with gastrointestinal dysfunction in simian immunodeficiency virus-infected pigtail macaques

Reconstitution of CD4 T cells in bronchoalveolar lavage fluid after initiation of highly active antiretroviral therapy

Residual immune dysregulation syndrome in treated HIV infection

SIV infection of rhesus macaques results in dysfunctional T- and B-cell responses to neo and recall Leishmania major vaccination.

SIV-induced Translocation of Bacterial Products in the Liver Mobilizes Myeloid Dendritic and Natural Killer Cells Associated With Liver Damage

Severe depletion of mucosal CD4+ T cells in AIDS-free simian immunodeficiency virus-infected sooty mangabeys

Short-lived infected cells support virus replication in sooty mangabeys naturally infected with simian immunodeficiency virus: implications for AIDS pathogenesis

Superior T memory stem cell persistence supports long-lived T cell memory

Th17 cell dynamics in HIV infection

Transcriptional Profiling of Experimental CD8+Lymphocyte Depletion in Rhesus Macaques Infected with Simian Immunodeficiency Virus SIVmac239 ⬇️

Vaginal bacteria modify HIV tenofovir microbicide efficacy in African women

Viral CTL Escape Mutants Are Generated in Lymph Nodes and Subsequently Become Fixed in Plasma and Rectal Mucosa during Acute SIV Infection of Macaques ⬇️

Why don't CD8+ T cells reduce the lifespan of SIV-infected cells in vivo?