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List of works by Christos Sotiriou

A fuzzy gene expression-based computational approach improves breast cancer prognostication

scientific article

A three-gene model to robustly identify breast cancer molecular subtypes

scientific article published on 18 January 2012

Adaptive immune signature in HER2-positive breast cancer in NCCTG (Alliance) N9831 and NeoALTTO trials

scientific article published on 24 May 2022

Alpha-smooth Muscle Actin Expression in the Stroma Predicts Resistance to Trastuzumab in Patients with Early-stage HER2-positive Breast Cancer

scientific article published on 31 August 2021

Amplification of LAPTM4B and YWHAZ contributes to chemotherapy resistance and recurrence of breast cancer

scientific article

Assessment of an RNA interference screen-derived mitotic and ceramide pathway metagene as a predictor of response to neoadjuvant paclitaxel for primary triple-negative breast cancer: a retrospective analysis of five clinical trials

scientific article

Author Correction: Landscape of somatic mutations in 560 breast cancer whole-genome sequences

scientific article published on 01 February 2019

Breast cancer classification and prognosis based on gene expression profiles from a population-based study

scientific article published on 13 August 2003

CD4⁺ follicular helper T cell infiltration predicts breast cancer survival

scientific article published on 17 June 2013

CD73 promotes resistance to HER2/ErbB2 antibody therapy

scientific article published on 30 August 2017

CDK4 phosphorylation status and a linked gene expression profile predict sensitivity to palbociclib

scientific article published on 31 May 2017

Characterization and clinical evaluation of CD10+ stroma cells in the breast cancer microenvironment

scientific article published on 10 January 2012

Comparison of prognostic gene expression signatures for breast cancer

scientific article

Consistent metagenes from cancer expression profiles yield agent specific predictors of chemotherapy response

scientific article

Constitutive phosphorylated STAT3-associated gene signature is predictive for trastuzumab resistance in primary HER2-positive breast cancer

scientific article published on 3 August 2015

DNA methylation profiling reveals a predominant immune component in breast cancers.

scientific article

DNA methylation-based immune response signature improves patient diagnosis in multiple cancers

scientific article published on 17 July 2017

Definition of clinically distinct molecular subtypes in estrogen receptor-positive breast carcinomas through genomic grade

scientific article

Gene modules and response to neoadjuvant chemotherapy in breast cancer subtypes: a pooled analysis.

scientific article

Genomic Evolution of Breast Cancer Metastasis and Relapse

scientific article published on August 2017

Genomic grade index is associated with response to chemotherapy in patients with breast cancer

scientific article published on 13 April 2009

HER2-Overexpressing Breast Cancers Amplify FGFR Signaling upon Acquisition of Resistance to Dual Therapeutic Blockade of HER2.

scientific article published on 5 April 2017

HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures

scientific article published on 13 March 2017

Improved Treatment of Breast Cancer with Anti-HER2 Therapy Requires Interleukin-21 Signaling in CD8+ T Cells

scientific article published on 7 January 2016

Improvement of the clinical applicability of the Genomic Grade Index through a qRT-PCR test performed on frozen and formalin-fixed paraffin-embedded tissues

scientific article

Inhibition of RANK signaling in breast cancer induces an anti-tumor immune response orchestrated by CD8+ T cells

scientific article published on 10 December 2020

Integrative proteomic and gene expression analysis identify potential biomarkers for adjuvant trastuzumab resistance: analysis from the Fin-her phase III randomized trial

scientific article published on 3 September 2015

International expert consensus on primary systemic therapy in the management of early breast cancer: highlights of the Fourth Symposium on Primary Systemic Therapy in the Management of Operable Breast Cancer, Cremona, Italy (2010).

scientific article published on January 2011

International network of cancer genome projects

scientific article

Landscape of somatic mutations in 560 breast cancer whole-genome sequences

scientific article

Loss of ARID1A Activates ANXA1, which Serves as a Predictive Biomarker for Trastuzumab Resistance.

scientific article

Low residual proliferation after short-term letrozole therapy is an early predictive marker of response in high proliferative ER-positive breast cancer.

scientific article published on 14 November 2011

Meta-analysis of gene expression profiles in breast cancer: toward a unified understanding of breast cancer subtyping and prognosis signatures

scientific article published on 28 July 2008

Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes

scientific article

Multifactorial approach to predicting resistance to anthracyclines

scientific article published on 21 March 2011

Multiple-input multiple-output causal strategies for gene selection

scientific article

Ontogeny and Vulnerabilities of Drug-Tolerant Persisters in HER2+ Breast Cancer

scientific article published in 2021

Predicting prognosis using molecular profiling in estrogen receptor-positive breast cancer treated with tamoxifen

scientific article

Somatic mutation profiling and associations with prognosis and trastuzumab benefit in early breast cancer

scientific article published on 05 June 2013

Somatic mutations reveal asymmetric cellular dynamics in the early human embryo

scientific article

Strong time dependence of the 76-gene prognostic signature for node-negative breast cancer patients in the TRANSBIG multicenter independent validation series

scientific article published in June 2007

Subclonal diversification of primary breast cancer revealed by multiregion sequencing

scientific article published on 22 June 2015

The Gene expression Grade Index: a potential predictor of relapse for endocrine-treated breast cancer patients in the BIG 1-98 trial

scientific article

The topography of mutational processes in breast cancer genomes

scientific article published on 02 May 2016

Time to move forward from “first-generation” prognostic gene signatures in early breast cancer

article

Transfer of clinically relevant gene expression signatures in breast cancer: from Affymetrix microarray to Illumina RNA-Sequencing technology

scientific article

Tumor PIK3CA Genotype and Prognosis in Early-Stage Breast Cancer: A Pooled Analysis of Individual Patient Data

scientific article published on 22 February 2018

Tumor-Infiltrating Lymphocytes and Prognosis: A Pooled Individual Patient Analysis of Early-Stage Triple-Negative Breast Cancers

scientific article published on 16 January 2019

Use of cancer-specific genomic rearrangements to quantify disease burden in plasma from patients with solid tumors

scientific article

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