Advanced search

Authors whose works are in public domain in at least one jurisdiction

List of works by Francis J Castellino

51-100 of 165 results

View this query on the Wikidata Query Service
Generation of genetically-altered mice producing very low levels of coagulation factorVII

scientific article published on 01 September 2005
N-methyl-D-aspartate receptor inhibition by an apolipoprotein E-derived peptide relies on low-density lipoprotein receptor-associated protein

scientific article
The molecular basis of conantokin antagonism of NMDA receptor function

scientific article published on May 2007
Complement-mediated Opsonization of Invasive Group A Streptococcus pyogenes Strain AP53 Is Regulated by the Bacterial Two-component Cluster of Virulence Responder/Sensor (CovRS) System

scientific article published on 08 August 2013
Pharmacology of triheteromeric N-Methyl-d-Aspartate Receptors

scientific article published on February 23, 2016
Unique Genomic Arrangements in an Invasive Serotype M23 Strain of Streptococcus pyogenes Identify Genes That Induce Hypervirulence

scientific article published on September 15, 2014
Sulindac treatment alters collagen and matrilysin expression in adenomas of ApcMin/+ mice

scientific article
Factor VII deficiency impairs cutaneous wound healing in mice

scientific article published on 11 February 2010
Profibrinolytic effects of metalloproteinases during skin wound healing in the absence of plasminogen.

scientific article published on 13 March 2008
Coagulation factor XI improves host defence during murine pneumonia-derived sepsis independent of factor XII activation

scientific article published on 11 May 2017
The fibrinolytic system in dissemination and matrix protein deposition during a mycobacterium infection

scientific article published on August 2003
Functional dissection of Streptococcus pyogenes M5 protein: the hypervariable region is essential for virulence

scientific article
Conantokins and variants derived from cone snail venom inhibit naloxone-induced withdrawal jumping in morphine-dependent mice

scientific article
A CCR2 macrophage endocytic pathway mediates extravascular fibrin clearance in vivo.

scientific article published on 8 December 2015
A missense mutation in the sodium phosphate co-transporter Slc34a1 impairs phosphate homeostasis

scientific article published on 11 June 2008
A single amino acid replacement results in the Ca2+-induced self-assembly of a helical conantokin-based peptide

scientific article published in October 2004
Gene targeting of components of the fibrinolytic system

scientific article published on 01 January 2002
Early platelet dysfunction in a rodent model of blunt traumatic brain injury reflects the acute traumatic coagulopathy found in humans

scientific article
Functional differences between Streptococcus pyogenes cluster 1 and cluster 2b streptokinases are determined by their β‐domains

scientific article published on 07 March 2013
X-ray crystallographic structure of the angiogenesis inhibitor, angiostatin, bound to a peptide from the group A streptococcal surface protein PAM.

scientific article
NR2B-selective conantokin peptide inhibitors of the NMDA receptor display enhanced antinociceptive properties compared to non-selective conantokins

scientific article published on October 2008
Lack of plasminogen leads to milk stasis and premature mammary gland involution during lactation

scientific article published on 27 July 2006
Helix-helix interactions between homo- and heterodimeric gamma-carboxyglutamate-containing conantokin peptides and their derivatives.

scientific article
Structure-function analysis of the streptokinase amino terminus (residues 1-59).

scientific article
The lack of binding of VEK-30, an internal peptide from the group A streptococcal M-like protein, PAM, to murine plasminogen is due to two amino acid replacements in the plasminogen kringle-2 domain.

scientific article published on 26 November 2007
A fast-acting, modular-structured staphylokinase fusion with Kringle-1 from human plasminogen as the fibrin-targeting domain offers improved clot lysis efficacy

scientific article published on 19 March 2003
A severe deficiency of coagulation factor VIIa results in attenuation of the asthmatic response in mice

scientific article published on 13 March 2009
A new mechanism for metal ion-assisted interchain helix assembly in a naturally occurring peptide mediated by optimally spaced gamma-carboxyglutamic acid residues.

scientific article published in February 2004
Plasminogen activator inhibitor-1 stimulates macrophage activation through Toll-like Receptor-4.

scientific article published on 14 June 2016
A key role for the urokinase plasminogen activator (uPA) in invasive Group A streptococcal infection

scientific article
alpha Domain deletion converts streptokinase into a fibrin-dependent plasminogen activator through mechanisms akin to staphylokinase and tissue plasminogen activator

scientific article
Direct Host Plasminogen Binding to Bacterial Surface M-protein in Pattern D Strains of Streptococcus pyogenes Is Required for Activation by Its Natural Coinherited SK2b Protein

scientific article published on June 12, 2015
Characterization of a reduced form of plasma plasminogen as the precursor for angiostatin formation

scientific article published on 12 December 2013
CovRS-Regulated Transcriptome Analysis of a Hypervirulent M23 Strain of Group A Streptococcus pyogenes Provides New Insights into Virulence Determinants

scientific article published on July 27, 2015
Genomic Characterization of a Pattern D Streptococcus pyogenes emm53 Isolate Reveals a Genetic Rationale for Invasive Skin Tropicity

scientific article published on 04 April 2016
Fibrinolysis in Trauma: "Myth," "Reality," or "Something in Between".

scientific article published on 20 February 2017
The β-domain of cluster 2b streptokinase is a major determinant for the regulation of its plasminogen activation activity by cellular plasminogen receptors

scientific article published on January 31, 2014
Solution structure of the complex of VEK-30 and plasminogen kringle 2

scientific article
A deficiency of uPAR alters endothelial angiogenic function and cell morphology

scientific article
Conantokins inhibit NMDAR-dependent calcium influx in developing rat hippocampal neurons in primary culture with resulting effects on CREB phosphorylation

scientific article
Early coagulation events induce acute lung injury in a rat model of blunt traumatic brain injury.

scientific article published on 17 May 2016
Fibrinogen has chaperone-like activity

scientific article published on 04 December 2008
The selectivity of conantokin-G for ion channel inhibition of NR2B subunit-containing NMDA receptors is regulated by amino acid residues in the S2 region of NR2B.

scientific article
Blood component therapy in trauma guided with the utilization of the perfusionist and thromboelastography

scientific article published on September 1, 2011
Monoclonal antibodies detect receptor-induced binding sites in Glu-plasminogen

scientific article published on June 16, 2011
Dimerization is not a determining factor for functional high affinity human plasminogen binding by the group A streptococcal virulence factor PAM and is mediated by specific residues within the PAM a1a2 domain.

scientific article
Systemic platelet dysfunction is the result of local dysregulated coagulation and platelet activation in the brain in a rat model of isolated traumatic brain injury

scientific article published on 21 May 2014
Factor XI deficiency enhances the pulmonary allergic response to house dust mite in mice independent of factor XII.

scientific article
Streptococcus pyogenes Employs Strain-dependent Mechanisms of C3b Inactivation to Inhibit Phagocytosis and Killing of Bacteria

scientific article published on March 4, 2016
Variable region in streptococcal M-proteins provides stable binding with host fibrinogen for plasminogen-mediated bacterial invasion

scientific article published on 9 March 2017

Paulina is supported by:

About Paulina

Help